| 1 | ADAM17, SEMA4D, STING1
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| Activation of stimulator of interferon genes (STING) induces ADAM17-mediated shedding of the immune semaphorin SEMA4D.
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| Motani K, Kosako H.
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| J Biol Chem 293(20):7717-7726. doi: 10.1074/jbc.RA118.002175. Epub 2018 Apr 4.
2018
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| 2 | PLXNB1, SEMA4D
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| The Semaphorin 4D-Plexin-B1-RhoA signaling axis recruits pericytes and regulates vascular permeability through endothelial production of PDGF-B and ANGPTL4.
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| Zhou H, Yang YH, Basile JR.
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| Angiogenesis 17(1):261-74. doi: 10.1007/s10456-013-9395-0. Epub 2013 Oct 10.
2014
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| 3 | PLXNB1, SEMA4D
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| Does plexin-B1, a semaphorin 4D receptor, play a role in thrombosis?
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| Bird E, Smith PL, Seiffert D, Psaltis GC, Huang J, Schumacher WA.
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| Thromb Res 131(6):564-5. doi: 10.1016/j.thromres.2013.03.018. Epub 2013 Apr 30. No abstract available. 2013
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| 4 | MRAS, PLXNB1, RAPH1, SEMA4D
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| Semaphorin 4D/Plexin-B1-mediated M-Ras GAP activity regulates actin-based dendrite remodeling through Lamellipodin.
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| Tasaka G, Negishi M, Oinuma I.
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| J Neurosci 32(24):8293-305. doi: 10.1523/JNEUROSCI.0799-12.2012.
2012
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| 5 | PLXNB1, SEMA4D
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| Plexin-B1 and semaphorin 4D cooperate to promote perineural invasion in a RhoA/ROK-dependent manner.
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| Binmadi NO, Yang YH, Zhou H, Proia P, Lin YL, De Paula AM, Guimarães AL, Poswar FO, Sundararajan D, Basile JR.
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| Am J Pathol 180(3):1232-42. doi: 10.1016/j.ajpath.2011.12.009. Epub 2012 Jan 15.
2012
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| 6 | MET, PLXNB1, SEMA4D
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| Sema4D, the ligand for Plexin B1, suppresses c-Met activation and migration and promotes melanocyte survival and growth.
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| Soong J, Chen Y, Shustef EM, Scott GA.
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| J Invest Dermatol 132(4):1230-8. doi: 10.1038/jid.2011.414. Epub 2011 Dec 22.
2012
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| 7 | PLXNB1, SEMA4D
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| Plexin-B1 activates NF-κB and IL-8 to promote a pro-angiogenic response in endothelial cells.
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| Yang YH, Zhou H, Binmadi NO, Proia P, Basile JR.
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| PLoS One 6(10):e25826. doi: 10.1371/journal.pone.0025826. Epub 2011 Oct 18.
2011
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| 8 | PLXNB1, SEMA4D
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| Semaphorin 4D, a lymphocyte semaphorin, enhances tumor cell motility through binding its receptor, plexinB1, in pancreatic cancer.
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| Kato S, Kubota K, Shimamura T, Shinohara Y, Kobayashi N, Watanabe S, Yoneda M, Inamori M, Nakamura F, Ishiguro H, Nakaigawa N, Nagashima Y, Taguri M, Kubota Y, Goshima Y, Morita S, Endo I, Maeda S, Nakajima A, Nakagama H.
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| Cancer Sci 102(11):2029-37. doi: 10.1111/j.1349-7006.2011.02053.x. Epub 2011 Sep 13.
2011
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| 9 | PLXNB1, SEMA4D
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| Roles of Sema4D and Plexin-B1 in tumor progression.
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| Ch'ng ES, Kumanogoh A.
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| Mol Cancer 9:251. doi: 10.1186/1476-4598-9-251. Review.
2010
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| 10 | PLXNB1, PTEN, SEMA4D
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| Semaphorin 4D/Plexin-B1 stimulates PTEN activity through R-Ras GTPase-activating protein activity, inducing growth cone collapse in hippocampal neurons.
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| Oinuma I, Ito Y, Katoh H, Negishi M.
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| J Biol Chem 285(36):28200-9. doi: 10.1074/jbc.M110.147546. Epub 2010 Jul 7.
2010
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| 11 | PLXNB1, SEMA4D
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| Roles of Sema4D-plexin-B1 interactions in the central nervous system for pathogenesis of experimental autoimmune encephalomyelitis.
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| Okuno T, Nakatsuji Y, Moriya M, Takamatsu H, Nojima S, Takegahara N, Toyofuku T, Nakagawa Y, Kang S, Friedel RH, Sakoda S, Kikutani H, Kumanogoh A.
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| J Immunol 184(3):1499-506. doi: 10.4049/jimmunol.0903302. Epub 2009 Dec 28.
2010
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| 12 | PTPN11, SEMA4D
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| Protein tyrosine phosphatase SHP2 is involved in Semaphorin 4D-induced axon repulsion.
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| Fuchikawa T, Nakamura F, Fukuda N, Takei K, Goshima Y.
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| Biochem Biophys Res Commun 385(1):6-10. Epub 2009 May 9.
2009
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| 13 | PLCG1, PLCG2, PLXNB1, SEMA4D
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| Semaphorin 4D signaling requires the recruitment of phospholipase C gamma into the plexin-B1 receptor complex.
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| Swiercz JM, Worzfeld T, Offermanns S.
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| Mol Cell Biol 29(23):6321-34. Epub 2009 Oct 5. 2009
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| 14 | SEMA4D
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| Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury.
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| Zhu L, Bergmeier W, Wu J, Jiang H, Stalker TJ, Cieslak M, Fan R, Boumsell L, Kumanogoh A, Kikutani H, Tamagnone L, Wagner DD, Milla ME, Brass LF.
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| Proc Natl Acad Sci U S A 104(5):1621-6. Epub 2007 Jan 23. 2007
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| 15 | SEMA4D
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| Prognostic significance of CD100 expression in soft tissue sarcoma.
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| Ch'ng E, Tomita Y, Zhang B, He J, Hoshida Y, Qiu Y, Morii E, Nakamichi I, Hamada K, Ueda T, Aozasa K.
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| Cancer 110(1):164-72.
2007
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| 16 | SEMA4D, PLXNB1
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| Sema4D/plexin-B1 activates GSK-3beta through R-Ras GAP activity, inducing growth cone collapse.
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| Ito Y, Oinuma I, Katoh H, Kaibuchi K, Negishi M.
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| EMBO Rep 7(7):704-9. Epub 2006 Jun 16. 2006
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| 17 | SEMA4D, PLXNB1
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| Sema4D induces angiogenesis through Met recruitment by Plexin B1.
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| Conrotto P, Valdembri D, Corso S, Serini G, Tamagnone L, Comoglio PM, Bussolino F, Giordano S.
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| Blood 105(11):4321-9. Epub 2005 Jan 4. 2005
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| 18 | SEMA4D
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| Sema4D stimulates axonal outgrowth of embryonic DRG sensory neurones.
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| Masuda K, Furuyama T, Takahara M, Fujioka S, Kurinami H, Inagaki S.
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| Genes Cells 9(9):821-9. 2004
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| 19 | PLXNB1, PLXNB2, PLXNB3, SEMA4D
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| Plexin-B family members demonstrate non-redundant expression patterns in the developing mouse nervous system: an anatomical basis for morphogenetic effects of Sema4D during development.
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| Worzfeld T, Püschel AW, Offermanns S, Kuner R.
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| Eur J Neurosci 19(10):2622-32.
2004
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| 20 | SEMA4A, SEMA4D
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| Semaphorins in interactions between T cells and antigen-presenting cells.
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| Kikutani H, Kumanogoh A.
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| Nat Rev Immunol 3(2):159-67. Review.
2003
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| 21 | PLXNB1, RAC1, SEMA4D
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| The semaphorin receptor plexin-B1 specifically interacts with active rac in a ligand-dependent manner.
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| Vikis HG, Li W, He Z, Guan KL.
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| Proc Natl Acad Sci U S A 97(23):12457-62. 2000
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| 22 | SEMA3A, SEMA3B, SEMA3C, SEMA3F, SEMA4D, SEMA4F, SEMA5A, SEMA7A
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| Unified nomenclature of the semaphorins/collapsins
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| Semaphorin Nomenclature Committee
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| Cell (97) 551-2 1999
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| 23 | SEMA4D
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| Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation.
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| Hall KT, et al.
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| Proc Natl Acad Sci U S A 93(21):11780-5 1996
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