1 | ERBIN, LRRC1, SCRIB
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| LAP proteins are localized at the post-synaptic membrane of neuromuscular junctions and appear to modulate synaptic morphology and transmission.
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| Kravic B, Huraskin D, Frick AD, Jung J, Redai V, Palmisano R, Marchetto S, Borg JP, Mei L, Hashemolhosseini S.
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| J Neurochem 139(3):381-395. doi: 10.1111/jnc.13710.
2016
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2 | SCRIB, ZDHHC7
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| ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity
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| Chen B, Zheng B, DeRan M, Jarugumilli GK, Fu J, Brooks YS, Wu X.
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| Nat Chem Biol. Sep;12(9):686-93. doi: 10.1038/nchembio.2119. Epub 2016 Jul 4. 2016
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3 | CD74, SCRIB
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| CD74-dependent deregulation of the tumor suppressor scribble in human epithelial and breast cancer cells.
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| Metodieva G, Nogueira-de-Souza NC, Greenwood C, Al-Janabi K, Leng L, Bucala R, Metodiev MV.
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| Neoplasia 15(6):660-8.
2013
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4 | CELSR1, SCRIB
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| Mutations in the planar cell polarity genes CELSR1 and SCRIB are associated with the severe neural tube defect craniorachischisis.
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| Robinson A, Escuin S, Doudney K, Vekemans M, Stevenson RE, Greene ND, Copp AJ, Stanier P.
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| Hum Mutat 33(2):440-7. doi: 10.1002/humu.21662. Epub 2011 Dec 20.
2012
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5 | NOS1AP, SCRIB, VANGL1
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| A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression.
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| Anastas JN, Biechele TL, Robitaille M, Muster J, Allison KH, Angers S, Moon RT.
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| Oncogene 31(32):3696-708. doi: 10.1038/onc.2011.528. Epub 2011 Dec 19.
2012
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6 | SCRIB
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| SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia.
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| Pearson HB, Perez-Mancera PA, Dow LE, Ryan A, Tennstedt P, Bogani D, Elsum I, Greenfield A, Tuveson DA, Simon R, Humbert PO.
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| J Clin Invest 121(11):4257-67. doi: 10.1172/JCI58509. Epub 2011 Oct 3.
2011
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7 | SCRIB
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| Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling.
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| Doggett K, Grusche FA, Richardson HE, Brumby AM.
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| BMC Dev Biol 11:57.
2011
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8 | PHLPP1, SCRIB
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| Scribble-mediated membrane targeting of PHLPP1 is required for its negative regulation of Akt.
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| Li X, Yang H, Liu J, Schmidt MD, Gao T.
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| EMBO Rep 12(8):818-24. doi: 10.1038/embor.2011.106.
2011
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9 | SCRIB
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| Aberrant overexpression of the cell polarity module scribble in human cancer.
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| Vaira V, Faversani A, Dohi T, Maggioni M, Nosotti M, Tosi D, Altieri DC, Bosari S.
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| Am J Pathol 178(6):2478-83. Epub 2011 May 6.
2011
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10 | SCRIB
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| Immature T-cell clustering and efficient differentiation require the polarity protein Scribble.
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| Pike KA, Kulkarni S, Pawson T.
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| Proc Natl Acad Sci U S A 108(3):1116-21. Epub 2010 Dec 28.
2011
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11 | SCRIB, WWTR1
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| The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells.
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| Cordenonsi M, Zanconato F, Azzolin L, Forcato M, Rosato A, Frasson C, Inui M, Montagner M, Parenti AR, Poletti A, Daidone MG, Dupont S, Basso G, Bicciato S, Piccolo S.
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| Cell 147(4):759-72. doi: 10.1016/j.cell.2011.09.048.
2011
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12 | ARHGEF7, CTNNB1, SCRIB
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| β-Pix modulates actin-mediated recruitment of synaptic vesicles to synapses.
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| Sun Y, Bamji SX.
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| J Neurosci 31(47):17123-33. doi: 10.1523/JNEUROSCI.2359-11.2011.
2011
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13 | SCRIB
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| hScrib, a human homolog of Drosophila neoplastic tumor suppressor, is involved in the progress of endometrial cancer.
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| Ouyang Z, Zhan W, Dan L.
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| Oncol Res 18(11-12):593-9.
2010
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14 | SCRIB
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| The planar polarity protein Scribble1 is essential for neuronal plasticity and brain function.
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| Moreau MM, Piguel N, Papouin T, Koehl M, Durand CM, Rubio ME, Loll F, Richard EM, Mazzocco C, Racca C, Oliet SH, Abrous DN, Montcouquiol M, Sans N.
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| J Neurosci 30(29):9738-52.
2010
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15 | NOS1AP, SCRIB
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| NOS1AP associates with Scribble and regulates dendritic spine development.
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| Richier L, Williton K, Clattenburg L, Colwill K, O'Brien M, Tsang C, Kolar A, Zinck N, Metalnikov P, Trimble WS, Krueger SR, Pawson T, Fawcett JP.
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| J Neurosci 30(13):4796-805.
2010
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16 | MCC, SCRIB, SLC9A3R1, SLC9A3R2
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| MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells.
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| Arnaud C, Sebbagh M, Nola S, Audebert S, Bidaut G, Hermant A, Gayet O, Dusetti NJ, Ollendorff V, Santoni MJ, Borg JP, Lécine P.
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| FEBS Lett 583(14):2326-32. Epub 2009 Jun 24.
2009
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17 | RPS6KA3, PLD1, SCRIB
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| The Coffin-Lowry syndrome-associated protein RSK2 is implicated in calcium-regulated exocytosis through the regulation of PLD1.
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| Zeniou-Meyer M, Liu Y, Bgl A, Olanish M, Hanauer A, Becherer U, Rettig J, Bader MF, Vitale N.
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| Proc Natl Acad Sci U S A 105(24):8434-9. Epub 2008 Jun 11. 2008
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18 | ARHGEF7, GIT1, PAK1, PAK2, SCRIB
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| Scrib regulates PAK activity during the cell migration process.
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| Nola S, Sebbagh M, Marchetto S, Osmani N, Nourry C, Audebert S, Navarro C, Rachel R, Montcouquiol M, Sans N, Etienne-Manneville S, Borg JP, Santoni MJ.
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| Hum Mol Genet 17(22):3552-65. Epub 2008 Aug 20. 2008
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19 | DLG1, LLGL1, SCRIB
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| Regulation of the hDlg/hScrib/Hugl-1 tumour suppressor complex.
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| Massimi P, Narayan N, Thomas M, Gammoh N, Strand S, Strand D, Banks L.
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| Exp Cell Res 314(18):3306-17. Epub 2008 Sep 3.PMID: 18793635 2008
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20 | SCRIB, DLG1
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| The PDZ domain-binding motif of the human T cell leukemia virus type 1 tax protein induces mislocalization of the tumor suppressor hScrib in T cells.
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| Arpin-Andr C, Mesnard JM.
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| J Biol Chem 282(45):33132-41. Epub 2007 Sep 11. 2007
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21 | SCRIB, DLG1
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| Human discs large and scrib are localized at the same regions in colon mucosa and changes in their expression patterns are correlated with loss of tissue architecture during malignant progression.
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| Gardiol D, Zacchi A, Petrera F, Stanta G, Banks L.
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| Int J Cancer 119(6):1285-90. 2006
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22 | SCRIB, UBE3A
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| Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli.
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| Takizawa S, Nagasaka K, Nakagawa S, Yano T, Nakagawa K, Yasugi T, Takeuchi T, Kanda T, Huibregtse JM, Akiyama T, Taketani Y.
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| Genes Cells 11(4):453-64. 2006
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23 | LIN7C, SCRIB, SH3BP5, SYNJ2BP, MAPK12
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| Outer membrane protein 25-a mitochondrial anchor and inhibitor of stress-activated protein kinase-3.
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| Court NW, Ingley E, Klinken SP, Bogoyevitch MA.
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| Biochim Biophys Acta 1744(1):68-75. Epub 2004 Dec 31. 2005
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24 | SCRIB, TRIP6
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| The tumor suppressor Scrib selectively interacts with specific members of the zyxin family of proteins.
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| Petit MM, Crombez KR, Vervenne HB, Weyns N, Van de Ven WJ.
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| FEBS Lett 579(22):5061-8. 2005
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25 | DLG1, LLGL1, SCRIB
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| The human protein Hugl-1 substitutes for Drosophila lethal giant larvae tumour suppressor function in vivo.
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| Grifoni D, Garoia F, Schimanski CC, Schmitz G, Laurenti E, Galle PR, Pession A, Cavicchi S, Strand D.
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| Oncogene 23(53):8688-94.PMID: 15467749 2004
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26 | SCRIB, VANGL2
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| Identification of Vangl2 and Scrb1 as planar polarity genes in mammals.
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| Montcouquiol M, Rachel RA, Lanford PJ, Copeland NG, Jenkins NA, Kelley MW.
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| Nature 423(6936):173-7. 2003
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27 | SCRIB
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| Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase.
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| Nakagawa S, Huibregtse JM.
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| Mol Cell Biol 20(21):8244-53. 2000
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28 | ARID4B, BOP1, CACNA2D2, CCT5, CKAP5, CTR9, DCLRE1A, DELE1, DGKD, DHX34, EIF3A, EIF4A3, EMC1, EMC2, EXOSC7, FAM175B, FAM53B, GANAB, GGA3, GIT2, GPD1L, INPP5E, KEAP1, KIAA0082, KIAA0087, KIAA0114, KIAA0125, MAD2L1BP, MBTPS1, METAP1, MORC3, NCAPD2, NUP93, OEATC1, PASK, PMPCA, PRDX6, PSMD6, PUM1, RBM10, SAFB2, SART3, SCRIB, SERTAD2, SNRK, SPCS2, TAGLN2, THRAP4, TRIM14, TTLL12, UBAP2L, UBE4A, URB2, ZC3H3
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| Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1.
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| Nagase T, Miyajima N, Tanaka A, Sazuka T, Seki N, Sato S, Tabata S,Ishikawa K, Kawarabayasi Y, Kotani H, et al.
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| DNA Res 2(1):37-43. 1995
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