Citations for
1CELSR1, SCRIB
Mutations in the planar cell polarity genes CELSR1 and SCRIB are associated with the severe neural tube defect craniorachischisis.
Robinson A, Escuin S, Doudney K, Vekemans M, Stevenson RE, Greene ND, Copp AJ, Stanier P.
Hum Mutat 33(2):440-7. doi: 10.1002/humu.21662. Epub 2011 Dec 20. 2012
2SCRIB
SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia.
Pearson HB, Perez-Mancera PA, Dow LE, Ryan A, Tennstedt P, Bogani D, Elsum I, Greenfield A, Tuveson DA, Simon R, Humbert PO.
J Clin Invest 121(11):4257-67. doi: 10.1172/JCI58509. Epub 2011 Oct 3. 2011
3SCRIB
Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling.
Doggett K, Grusche FA, Richardson HE, Brumby AM.
BMC Dev Biol 11:57. 2011
4PHLPP1, SCRIB
Scribble-mediated membrane targeting of PHLPP1 is required for its negative regulation of Akt.
Li X, Yang H, Liu J, Schmidt MD, Gao T.
EMBO Rep 12(8):818-24. doi: 10.1038/embor.2011.106. 2011
5SCRIB
Aberrant overexpression of the cell polarity module scribble in human cancer.
Vaira V, Faversani A, Dohi T, Maggioni M, Nosotti M, Tosi D, Altieri DC, Bosari S.
Am J Pathol 178(6):2478-83. Epub 2011 May 6. 2011
6SCRIB
Immature T-cell clustering and efficient differentiation require the polarity protein Scribble.
Pike KA, Kulkarni S, Pawson T.
Proc Natl Acad Sci U S A 108(3):1116-21. Epub 2010 Dec 28. 2011
7SCRIB, WWTR1
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells.
Cordenonsi M, Zanconato F, Azzolin L, Forcato M, Rosato A, Frasson C, Inui M, Montagner M, Parenti AR, Poletti A, Daidone MG, Dupont S, Basso G, Bicciato S, Piccolo S.
Cell 147(4):759-72. doi: 10.1016/j.cell.2011.09.048. 2011
8ARHGEF7, CTNNB1, SCRIB
β-Pix modulates actin-mediated recruitment of synaptic vesicles to synapses.
Sun Y, Bamji SX.
J Neurosci 31(47):17123-33. doi: 10.1523/JNEUROSCI.2359-11.2011. 2011
9SCRIB
hScrib, a human homolog of Drosophila neoplastic tumor suppressor, is involved in the progress of endometrial cancer.
Ouyang Z, Zhan W, Dan L.
Oncol Res 18(11-12):593-9. 2010
10SCRIB
The planar polarity protein Scribble1 is essential for neuronal plasticity and brain function.
Moreau MM, Piguel N, Papouin T, Koehl M, Durand CM, Rubio ME, Loll F, Richard EM, Mazzocco C, Racca C, Oliet SH, Abrous DN, Montcouquiol M, Sans N.
J Neurosci 30(29):9738-52. 2010
11NOS1AP, SCRIB
NOS1AP associates with Scribble and regulates dendritic spine development.
Richier L, Williton K, Clattenburg L, Colwill K, O'Brien M, Tsang C, Kolar A, Zinck N, Metalnikov P, Trimble WS, Krueger SR, Pawson T, Fawcett JP.
J Neurosci 30(13):4796-805. 2010
12MCC, SCRIB, SLC9A3R1, SLC9A3R2
MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells.
Arnaud C, Sebbagh M, Nola S, Audebert S, Bidaut G, Hermant A, Gayet O, Dusetti NJ, Ollendorff V, Santoni MJ, Borg JP, Lécine P.
FEBS Lett 583(14):2326-32. Epub 2009 Jun 24. 2009
13RPS6KA3, PLD1, SCRIB
The Coffin-Lowry syndrome-associated protein RSK2 is implicated in calcium-regulated exocytosis through the regulation of PLD1.
Zeniou-Meyer M, Liu Y, BŽglŽ A, Olanish M, Hanauer A, Becherer U, Rettig J, Bader MF, Vitale N.
Proc Natl Acad Sci U S A 105(24):8434-9. Epub 2008 Jun 11. 2008
14ARHGEF7, GIT1, PAK1, PAK2, SCRIB
Scrib regulates PAK activity during the cell migration process.
Nola S, Sebbagh M, Marchetto S, Osmani N, Nourry C, Audebert S, Navarro C, Rachel R, Montcouquiol M, Sans N, Etienne-Manneville S, Borg JP, Santoni MJ.
Hum Mol Genet 17(22):3552-65. Epub 2008 Aug 20. 2008
15DLG1, LLGL1, SCRIB
Regulation of the hDlg/hScrib/Hugl-1 tumour suppressor complex.
Massimi P, Narayan N, Thomas M, Gammoh N, Strand S, Strand D, Banks L.
Exp Cell Res 314(18):3306-17. Epub 2008 Sep 3.PMID: 18793635 2008
16SCRIB, DLG1
The PDZ domain-binding motif of the human T cell leukemia virus type 1 tax protein induces mislocalization of the tumor suppressor hScrib in T cells.
Arpin-AndrŽ C, Mesnard JM.
J Biol Chem 282(45):33132-41. Epub 2007 Sep 11. 2007
17SCRIB, DLG1
Human discs large and scrib are localized at the same regions in colon mucosa and changes in their expression patterns are correlated with loss of tissue architecture during malignant progression.
Gardiol D, Zacchi A, Petrera F, Stanta G, Banks L.
Int J Cancer 119(6):1285-90. 2006
18SCRIB, UBE3A
Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli.
Takizawa S, Nagasaka K, Nakagawa S, Yano T, Nakagawa K, Yasugi T, Takeuchi T, Kanda T, Huibregtse JM, Akiyama T, Taketani Y.
Genes Cells 11(4):453-64. 2006
19LIN7C, SCRIB, SH3BP5, SYNJ2BP, MAPK12
Outer membrane protein 25-a mitochondrial anchor and inhibitor of stress-activated protein kinase-3.
Court NW, Ingley E, Klinken SP, Bogoyevitch MA.
Biochim Biophys Acta 1744(1):68-75. Epub 2004 Dec 31. 2005
20SCRIB, TRIP6
The tumor suppressor Scrib selectively interacts with specific members of the zyxin family of proteins.
Petit MM, Crombez KR, Vervenne HB, Weyns N, Van de Ven WJ.
FEBS Lett 579(22):5061-8. 2005
21DLG1, LLGL1, SCRIB
The human protein Hugl-1 substitutes for Drosophila lethal giant larvae tumour suppressor function in vivo.
Grifoni D, Garoia F, Schimanski CC, Schmitz G, Laurenti E, Galle PR, Pession A, Cavicchi S, Strand D.
Oncogene 23(53):8688-94.PMID: 15467749 2004
22SCRIB, VANGL2
Identification of Vangl2 and Scrb1 as planar polarity genes in mammals.
Montcouquiol M, Rachel RA, Lanford PJ, Copeland NG, Jenkins NA, Kelley MW.
Nature 423(6936):173-7. 2003
23SCRIB
Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase.
Nakagawa S, Huibregtse JM.
Mol Cell Biol 20(21):8244-53. 2000
24ARID4B, BOP1, CACNA2D2, CCT5, CKAP5, CTR9, DCLRE1A, DGKD, DHX34, EIF3A, EIF4A3, EXOSC7, FAM175B, FAM53B, GANAB, GGA3, GIT2, GPD1L, INPP5E, KEAP1, KIAA0082, KIAA0087, KIAA0090, KIAA0114, KIAA0125, KIAA0141, MAD2L1BP, MBTPS1, METAP1, MORC3, NCAPD2, NUP93, OEATC1, PASK, PMPCA, PRDX6, PSMD6, PUM1, RBM10, SAFB2, SART3, SCRIB, SERTAD2, SNRK, SPCS2, TAGLN2, THRAP4, TRIM14, TTC35, TTLL12, UBAP2L, UBE4A, URB2, ZC3H3
Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1.
Nagase T, Miyajima N, Tanaka A, Sazuka T, Seki N, Sato S, Tabata S,Ishikawa K, Kawarabayasi Y, Kotani H, et al.
DNA Res 2(1):37-43. 1995