| 1 | PCSK1N, SCG5
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| Blockade of islet amyloid polypeptide fibrillation and cytotoxicity by the secretory chaperones 7B2 and proSAAS.
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| Peinado JR, Sami F, Rajpurohit N, Lindberg I.
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| FEBS Lett 587(21):3406-11. doi: 10.1016/j.febslet.2013.09.006. Epub 2013 Sep 13.
2013
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| 2 | SCG5
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| The neuroendocrine protein 7B2 suppresses the aggregation of neurodegenerative disease-related proteins.
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| Helwig M, Hoshino A, Berridge C, Lee SN, Lorenzen N, Otzen DE, Eriksen JL, Lindberg I.
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| J Biol Chem 288(2):1114-24. doi: 10.1074/jbc.M112.417071. Epub 2012 Nov 21.
2013
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| 3 | SCG5
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| The neuroendocrine protein 7B2 is intrinsically disordered.
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| Dasgupta I, Sanglas L, Enghild JJ, Lindberg I.
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| Biochemistry 51(38):7456-64. doi: 10.1021/bi300871k. Epub 2012 Sep 14.
2012
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| 4 | SCG5
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| Frequent epigenetic inactivation of the chaperone SGNE1/7B2 in human gliomas.
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| Waha A, Felsberg J, Hartmann W, Hammes J, von dem Knesebeck A, Endl E, Pietsch T, Waha A.
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| Int J Cancer 131(3):612-22. doi: 10.1002/ijc.26416. Epub 2011 Oct 5.
2012
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| 5 | SCG5
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| Regulation of 7B2 mRNA translation: dissecting the role of its 5'-untranslated region.
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| Tadros H, Schmidt G, Sirois F, Mbikay M.
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| Methods Mol Biol 768:217-30. doi: 10.1007/978-1-61779-204-5_11.
2011
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| 6 | PCSK2, SCG5
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| Dynamic modulation of prohormone convertase 2 (PC2)-mediated precursor processing by 7B2 protein: preferential effect on glucagon synthesis.
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| Helwig M, Lee SN, Hwang JR, Ozawa A, Medrano JF, Lindberg I.
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| J Biol Chem 286(49):42504-13. doi: 10.1074/jbc.M111.281980. Epub 2011 Oct 19.
2011
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| 7 | PCSK2, SCG5
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| PCSK2-null mice exhibit delayed intestinal motility, reduced refeeding response and altered plasma levels of several regulatory peptides.
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| Gagnon J, Mayne J, Chen A, Raymond A, Woulfe J, Mbikay M, Chrétien M.
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| Life Sci 88(5-6):212-7. doi: 10.1016/j.lfs.2010.11.010. Epub 2010 Nov 16.
2011
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| 8 | CRAC1, GREM1, SCG5
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| Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk.
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| Jaeger E, Webb E, Howarth K, Carvajal-Carmona L, Rowan A, Broderick P, Walther A, Spain S, Pittman A, Kemp Z, Sullivan K, Heinimann K, Lubbe S, Domingo E, Barclay E, Martin L, Gorman M, Chandler I, Vijayakrishnan J, Wood W, Papaemmanuil E, Penegar S, Qureshi M; CORGI Consortium, Farrington S, Tenesa A, Cazier JB, Kerr D, Gray R, Peto J, Dunlop M, Campbell H, Thomas H, Houlston R, Tomlinson I.
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| Nat Genet 40(1):26-8. Epub 2007 Dec 16.
2008
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| 9 | SCG5
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| Overexpression of Scg5 increases enzymatic activity of PCSK2 and is inversely correlated with body weight in congenic mice.
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| Farber CR, Chitwood J, Lee SN, Verdugo RA, Islas-Trejo A, Rincon G, Lindberg I, Medrano JF.
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| BMC Genet 9:34. doi: 10.1186/1471-2156-9-34.
2008
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| 10 | PCSK2, SCG5
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| 7B2 prevents unfolding and aggregation of prohormone convertase 2.
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| Lee SN, Lindberg I.
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| Endocrinology 149(8):4116-27. doi: 10.1210/en.2008-0064. Epub 2008 May 8.
2008
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| 11 | SCG5
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| SGNE1/7B2 is epigenetically altered and transcriptionally downregulated in human medulloblastomas.
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| Waha A, Koch A, Hartmann W, Milde U, Felsberg J, Hübner A, Mikeska T, Goodyer CG, Sörensen N, Lindberg I, Wiestler OD, Pietsch T, Waha A.
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| Oncogene 26(38):5662-8. Epub 2007 Mar 5.
2007
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| 12 | SCG5
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| Secretory granule neuroendocrine protein 1 (SGNE1) genetic variation and glucose intolerance in severe childhood and adult obesity.
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| Bouatia-Naji N, Vatin V, Lecoeur C, Heude B, Proença C, Veslot J, Jouret B, Tichet J, Charpentier G, Marre M, Balkau B, Froguel P, Meyre D.
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| BMC Med Genet 8:44.
2007
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| 13 | SCG5
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| A fully functional proopiomelanocortin/melanocortin-1 receptor system regulates the differentiation of human scalp hair follicle melanocytes.
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| Kauser S, Thody AJ, Schallreuter KU, Gummer CL, Tobin DJ.
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| Endocrinology 146(2):532-43. Epub 2004 Oct 21.
2005
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| 14 | PCSK1N, SCG5
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| Functional characterization of ProSAAS: similarities and differences with 7B2.
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| Fortenberry Y, Hwang JR, Apletalina EV, Lindberg I.
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| J Biol Chem 277(7):5175-86. 2002
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| 15 | SCG5
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| Neuroendocrine secretory protein 7B2: structure, expression and functions.
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| Mbikay M, Seidah NG, Chrétien M.
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| Biochem J 357(Pt 2):329-42. Review.
2001
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| 16 | SCG5
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| Assignment of the gene for neuroendocrine protein 7B2 (SGNE1 locus) to mouse chromosome region 2[E3-F3] and to human chromosome region 15q11-q15.
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| Mattei MG, et al.
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| Genomics 6 : 436-440. 1990
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| 17 | SCG5
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| Regional mapping of the human gene encoding the novel pituitary polypeptide 7B2 to chromosome 15q13-q14 by in situ hybridization.
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| Roebroek AJM, et al.
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| Cytogenet Cell Genet 50 : 158-160. 1989
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