| 1 | ADM, AGTRAP, ALOX5, ENTPD1, IRAK3, MMP9, S100A8
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| Identification of key pathogenic genes of sepsis based on the Gene Expression Omnibus database.
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| Lu X, Xue L, Sun W, Ye J, Zhu Z, Mei H.
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| Mol Med Rep. Feb;17(2):3042-3054. doi: 10.3892/mmr.2017.8258. Epub 2017 Dec 12 2018
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| 2 | S100A8, S100A9
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| Proteins S100A8 and S100A9 are potential biomarkers for renal cell carcinoma in the early stages: Results from a proteomic study integrated with bioinformatics analysis.
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| Zhang L, Jiang H, Xu G, Wen H, Gu B, Liu J, Mao S, Na R, Jing Y, Ding Q, Zhang Y.
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| Mol Med Rep ol Med Rep. 2015 Feb 9. doi: 10.3892/mmr.2015.3321. [Epub ahead of print]
2015
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| 3 | S100A8, S100A9
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| Autocrine pathways involving S100A8 and/or S100A9 that are postulated to regulate the immunological functions of macrophages in rats.
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| Okada K, Arai S, Nakase H, Kohno H, Nakamura F, Takeda M, Toda Y, Itoh H, Adachi S, Ikemoto M.
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| Biochem Biophys Res Commun 456(1):415-20. doi: 10.1016/j.bbrc.2014.11.099. Epub 2014 Dec 6.
2015
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| 4 | S100A12, S100A8, S100A9
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| Secretion of S100A8, S100A9, and S100A12 by Neutrophils Involves Reactive Oxygen Species and Potassium Efflux.
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| Tardif MR, Chapeton-Montes JA, Posvandzic A, Pagé N, Gilbert C, Tessier PA.
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| J Immunol Res 2015:296149. doi: 10.1155/2015/296149. Epub 2015 Dec 30.
2015
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| 5 | S100A8, S100A9
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| S-calprotectin (S100A8/S100A9): a potential marker of inflammation in patients with psoriatic arthritis.
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| Hansson C, Eriksson C, Alenius GM.
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| J Immunol Res 2014:696415. doi: 10.1155/2014/696415. Epub 2014 May 14.
2014
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| 6 | S100A8
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| Impact of S100A8 expression on kidney cancer progression and molecular docking studies for kidney cancer therapeutics.
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| Mirza Z, Schulten HJ, Farsi HM, Al-Maghrabi JA, Gari MA, Chaudhary AG, Abuzenadah AM, Al-Qahtani MH, Karim S.
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| Anticancer Res 34(4):1873-84.
2014
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| 7 | S100A8, S100A9
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| Potential prognostic biomarkers of pancreatic cancer.
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| Chen KT, Kim PD, Jones KA, Devarajan K, Patel BB, Hoffman JP, Ehya H, Huang M, Watson JC, Tokar JL, Yeung AT.
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| Pancreas 43(1):22-7. doi: 10.1097/MPA.0b013e3182a6867e.
2014
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| 8 | ABCG1, IL22, S100A12, S100A8, S100A9
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| IL-22 is induced by S100/calgranulin and impairs cholesterol efflux in macrophages by downregulating ABCG1.
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| Chellan B, Yan L, Sontag TJ, Reardon CA, Hofmann Bowman MA.
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| J Lipid Res 55(3):443-54. doi: 10.1194/jlr.M044305. Epub 2013 Dec 23.
2014
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| 9 | S100A8, S100A9
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| S100A8 and S100A9 induce cytokine expression and regulate the NLRP3 inflammasome via ROS-dependent activation of NF-κB(1.).
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| Simard JC, Cesaro A, Chapeton-Montes J, Tardif M, Antoine F, Girard D, Tessier PA.
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| PLoS One 8(8):e72138. doi: 10.1371/journal.pone.0072138. eCollection 2013.
2013
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| 10 | S100A8, S100A9
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| S100A8/A9 (calprotectin) negatively regulates G2/M cell cycle progression and growth of squamous cell carcinoma.
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| Khammanivong A, Wang C, Sorenson BS, Ross KF, Herzberg MC.
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| PLoS One 8(7):e69395. doi: 10.1371/journal.pone.0069395. Print 2013.
2013
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| 11 | S100A8, S100A9
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| Human S100A9 protein is stabilized by inflammatory stimuli via the formation of proteolytically-resistant homodimers.
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| Riva M, He Z, Källberg E, Ivars F, Leanderson T.
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| PLoS One 8(4):e61832. doi: 10.1371/journal.pone.0061832. Print 2013.
2013
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| 12 | S100A8, S100A9
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| S100A8 and S100A9 are messengers in the crosstalk between epidermis and dermis modulating a psoriatic milieu in human skin.
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| Lee Y, Jang S, Min JK, Lee K, Sohn KC, Lim JS, Im M, Lee HE, Seo YJ, Kim CD, Lee JH.
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| Biochem Biophys Res Commun 423(4):647-53. doi: 10.1016/j.bbrc.2012.05.162. Epub 2012 Jun 7.
2012
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| 13 | S100A8, S100A9
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| Molecular interface of S100A8 with cytochrome b558 and NADPH oxidase activation.
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| Berthier S, Nguyen MV, Baillet A, Hograindleur MA, Paclet MH, Polack B, Morel F.
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| PLoS One 7(7):e40277. doi: 10.1371/journal.pone.0040277. Epub 2012 Jul 10.
2012
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| 14 | S100A8, S100A9
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| Oncogenic Kras expression in postmitotic neurons leads to S100A8-S100A9 protein overexpression and gliosis.
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| Ryu MJ, Liu Y, Zhong X, Du J, Peterson N, Kong G, Li H, Wang J, Salamat S, Chang Q, Zhang J.
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| J Biol Chem 287(27):22948-58. doi: 10.1074/jbc.M112.357772. Epub 2012 May 10. Erratum in: J Biol Chem. 2013 Dec 27;288(52):37367.
2012
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| 15 | S100A8, S100A9
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| Distinct roles for S100a8 in early embryo development and in the maternal deciduum.
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| Baker JR, Jeffery R, May RD, Mathies M, Spencer-Dene B, Poulsom R, Hogg N.
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| Dev Dyn 240(9):2194-203. doi: 10.1002/dvdy.22709.
2011
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| 16 | S100A8, S100A9
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| RAGE-dependent regulation of calcium-binding proteins S100A8 and S100A9 in human THP-1.
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| Eggers K, Sikora K, Lorenz M, Taubert T, Moobed M, Baumann G, Stangl K, Stangl V.
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| Exp Clin Endocrinol Diabetes 119(6):353-7. doi: 10.1055/s-0030-1268426. Epub 2011 Apr 6.
2011
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| 17 | RAB30, S100A8, S100A9
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| Elevation and characteristics of Rab30 and S100a8/S100a9 expression in an early phase of liver regeneration in the mouse.
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| Chiba M, Murata S, Myronovych A, Kohno K, Hiraiwa N, Nishibori M, Yasue H, Ohkohchi N.
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| Int J Mol Med 27(4):567-74. doi: 10.3892/ijmm.2011.614. Epub 2011 Feb 9.
2011
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| 18 | S100A8, S100A9
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| The antimicrobial heterodimer S100A8/S100A9 (calprotectin) is upregulated by bacterial flagellin in human epidermal keratinocytes.
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| Abtin A, Eckhart L, Gläser R, Gmeiner R, Mildner M, Tschachler E.
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| J Invest Dermatol 130(10):2423-30. doi: 10.1038/jid.2010.158. Epub 2010 Jun 17.
2010
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| 19 | S100A8, S100A9
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| IL-10-dependent S100A8 gene induction in monocytes/macrophages by double-stranded RNA.
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| Endoh Y, Chung YM, Clark IA, Geczy CL, Hsu K.
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| J Immunol 182(4):2258-68. doi: 10.4049/jimmunol.0802683.
2009
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| 20 | DIABLO, HTRA2, S100A8, S100A9
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| S100A8/9 induces cell death via a novel, RAGE-independent pathway that involves selective release of Smac/DIABLO and Omi/HtrA2.
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| Ghavami S, Kerkhoff C, Chazin WJ, Kadkhoda K, Xiao W, Zuse A, Hashemi M, Eshraghi M, Schulze-Osthoff K, Klonisch T, Los M.
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| Biochim Biophys Acta 1783(2):297-311. Epub 2007 Nov 7. 2008
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| 21 | CTNNAL1, FLT1, GSTP1, LEP, PAPPA2, S100A8, WWTR1
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| Seven placental transcripts characterize HELLP-syndrome.
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| Buimer M, Keijser R, Jebbink JM, Wehkamp D, van Kampen AH, Boer K, van der Post JA, Ris-Stalpers C.
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| Placenta 29(5):444-53.
2008
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| 22 | S100A8, S100A9
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| Biophysical characterization of S100A8 and S100A9 in the absence and presence of bivalent cations.
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| Vogl T, Leukert N, Barczyk K, Strupat K, Roth J.
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| Biochim Biophys Acta 1763(11):1298-306. Epub 2006 Aug 25. 2006
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| 23 | S100A8, S100A9
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| Molecular basis of the complex formation between the two calcium-binding proteins S100A8 (MRP8) and S100A9 (MRP14).
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| Leukert N, Sorg C, Roth J.
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| Biol Chem 386(5):429-34. 2005
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| 24 | S100A10, S100A11, S100A8, SLPI
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| A search for candidate genes for lipodystrophy, obesity and diabetes via gene expression analysis of A-ZIP/F-1 mice.
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| Mir AA, Myakishev MV, Polesskaya OO, Moitra J, Petersen D, Miller L, Orosz A, Vinson C.
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| Genomics 81(4):378-90. 2003
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| 25 | S100A8, S100A9
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| Blockade of S100A8 and S100A9 suppresses neutrophil migration in response to lipopolysaccharide.
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| Vandal K, Rouleau P, Boivin A, Ryckman C, Talbot M, Tessier PA.
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| J Immunol 171(5):2602-9. 2003
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| 26 | PSORS4, S100A8, S100A9
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| Evidence for differential S100 gene over-expression in psoriatic patients from genetically heterogeneous pedigrees.
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| Semprini S, Capon F, Tacconelli A, Giardina E, Orecchia A, Mingarelli R, Gobello T, Zambruno G, Botta A, Fabrizi G, Novelli G.
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| Hum Genet 111(4-5):310-3. 2002
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| 27 | S100A8, S100A9
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| Calgranulins S100A8 and S100A9 are negatively regulated by glucocorticoids in a c-Fos-dependent manner and overexpressed throughout skin carcinogenesis.
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| Gebhardt C, Breitenbach U, Tuckermann JP, Dittrich BT, Richter KH, Angel P.
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| Oncogene 21(27):4266-76. 2002
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| 28 | S100A8, S100A9
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| The S100A8/A9 protein as a partner for the cytosolic factors of NADPH oxidase activation in neutrophils.
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| Doussiere J, Bouzidi F, Vignais PV.
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| Eur J Biochem 269(13):3246-55. 2002
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| 29 | S100A8, S100A9
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| Selective expression of calcium-binding proteins S100a8 and S100a9 at distinct sites of hair follicles.
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| Schmidt M, Gillitzer R, Toksoy A, Brocker EB, Rapp UR, Paus R, Roth J, Ludwig S, Goebeler M.
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| J Invest Dermatol 117(3):748-50. No abstract available. 2001
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| 30 | S100A12, S100A8, S100A9
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| S100A12 is expressed exclusively by granulocytes and acts independently from MRP8 and MRP14.
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| Vogl T, Propper C, Hartmann M, Strey A, Strupat K, van den Bos C, Sorg C, Roth J.
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| J Biol Chem 274(36):25291-6 1999
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| 31 | FLG, IVL, LOR, S100A10, S100A6, S100A8, S100A9, SPRR1B, SPRR2A, SPRR3, TCHH
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| Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex (epidermal differentiation complex) on human chromosome 1q21.
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| Mischke D, Korge BP, Marenholz I, Volz A, Ziegler A.
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| J Invest Dermatol 106 : 989-992. 1996
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| 32 | S100A1, S100A2, S100A3, S100A4, S100A5, S100A6, S100A7, S100A8, S100A9, S100P
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| Six S100 genes are clustered on human chromosome 1q21 : identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E.
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| Engelkamp D, et al.
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| Proc Natl Acad Sci U S A 90 : 6547-6551. 1993
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| 33 | S100A8
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| The granulocyte protein cystic fibrosis antigen (CFAG) is a calcium binding protein mapping to chromosome 1q12-q21.
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| Dorin J, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 608. 1987
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| 34 | S100A8
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| A clue to the basic defect in cystic fibrosis from cloning the CF antigen gene.
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| Dorin JR, et al.
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| Nature 326 : 614-617. 1987
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| 35 | S100A8, S100A9
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| Tissue localization and chromosomal assignment of a serum protein thattracks the cystic fibrosis gene.
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| Van Heyningen V, et al.
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| Nature 315 : 513-515. 1985
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| 36 | S100A8, S100A9
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| Vogl T, Tenbrock K, Ludwig S, Leukert N, Ehrhardt C, van Zoelen MA, Nacken W, Foell D, van der Poll T, Sorg C, Roth J.
|
|
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| Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock rp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock. 0
|