1 | RXFP1
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| Investigation of Interactions at the Extracellular Loops of the Relaxin Family Peptide Receptor 1 (RXFP1).
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| Diepenhorst NA, Petrie EJ, Chen CZ, Wang A, Hossain MA, Bathgate RA, Gooley PR.
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| J Biol Chem Biol Chem. 2014 Oct 28. pii: jbc.M114.600882. [Epub ahead of print]
2014
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2 | RXFP1
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| Identification of small-molecule agonists of human relaxin family receptor 1 (RXFP1) by using a homogenous cell-based cAMP assay.
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| Chen CZ, Southall N, Xiao J, Marugan JJ, Ferrer M, Hu X, Jones RE, Feng S, Agoulnik IU, Zheng W, Agoulnik AI.
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| J Biomol Screen 18(6):670-7. doi: 10.1177/1087057112469406. Epub 2012 Dec 4.
2013
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3 | RLN2, RLN3, RXFP1, RXFP2
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| The relaxin receptor (RXFP1) utilizes hydrophobic moieties on a signaling surface of its N-terminal low density lipoprotein class A module to mediate receptor activation.
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| Kong RC, Petrie EJ, Mohanty B, Ling J, Lee JC, Gooley PR, Bathgate RA.
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| J Biol Chem 288(39):28138-51. doi: 10.1074/jbc.M113.499640. Epub 2013 Aug 7.
2013
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4 | RXFP1
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| Expression of RXFP1 in skin of scleroderma patients and control subjects.
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| Giordano N, Volpi N, Franci D, Corallo C, Fioravanti A, Papakostas P, Montella A, Biagioli M, Fimiani M, Grasso G, Muscettola MM, Guerranti R, Vannoni D, Galeazzi M, Nuti R.
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| Scand J Rheumatol 41(5):391-5. doi: 10.3109/03009742.2012.669496.
2012
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5 | RLN1, RLN3, RXFP1, RXFP2
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| The different ligand-binding modes of relaxin family peptide receptors RXFP1 and RXFP2.
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| Scott DJ, Rosengren KJ, Bathgate RA.
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| Mol Endocrinol 26(11):1896-906. doi: 10.1210/me.2012-1188. Epub 2012 Sep 12.
2012
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6 | RLN2, RXFP1, RXFP2
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| Relaxin 2 is functional at the ocular surface and promotes corneal wound healing.
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| Hampel U, Klonisch T, Makrantonaki E, Sel S, Schulze U, Garreis F, Seltmann H, Zouboulis CC, Paulsen FP.
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| Invest Ophthalmol Vis Sci 53(12):7780-90. doi: 10.1167/iovs.12-10714. Erratum in: Invest Ophthalmol Vis Sci. 2014;55(6):3998. Makrantonaki, Eugenia [added 2012
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7 | RXFP1
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| Endometrial LGR7 expression during menstrual cycle.
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| Campitiello MR, De Franciscis P, Mele D, Izzo G, Sinisi A, Delrio G, Colacurci N.
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| Fertil Steril 95(8):2511-4. doi: 10.1016/j.fertnstert.2011.01.124. Epub 2011 Feb 16.
2011
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8 | RLN3, RXFP1
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| H3 relaxin demonstrates antifibrotic properties via the RXFP1 receptor.
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| Hossain MA, Man BC, Zhao C, Xu Q, Du XJ, Wade JD, Samuel CS.
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| Biochemistry 50(8):1368-75. doi: 10.1021/bi1013968. Epub 2011 Jan 31.
2011
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9 | RLN3, RXFP1, RXFP2, RXFP3, RXFP4
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| Relaxin family peptides in the male reproductive system--a critical appraisal.
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| Ivell R, Kotula-Balak M, Glynn D, Heng K, Anand-Ivell R.
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| Mol Hum Reprod 17(2):71-84. doi: 10.1093/molehr/gaq086. Epub 2010 Oct 14. Review.
2011
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10 | RLN1, RXFP1
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| Relaxin stimulates osteoclast differentiation and activation.
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| Ferlin A, Pepe A, Facciolli A, Gianesello L, Foresta C.
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| Bone 46(2):504-13. Epub 2009 Oct 13.PMID: 19833242 2010
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11 | RLN1, RXFP1
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| Relaxin signaling activates peroxisome proliferator-activated receptor gamma.
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| Singh S, Bennett RG.
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| Mol Cell Endocrinol 315(1-2):239-45. Epub 2009 Aug 25.PMID: 19712722 2010
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12 | RXFP1
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| Characterization of relaxin receptor (RXFP1) desensitization and internalization in primary human decidual cells and RXFP1-transfected HEK293 cells.
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| Kern A, Bryant-Greenwood GD.
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| Endocrinology 150(5):2419-28. Epub 2008 Dec 30.PMID: 19116340 2009
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13 | RXFP1
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| RXFP1-inactive relaxin activates human glucocorticoid receptor: further investigations into the relaxin-GR pathway.
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| Dschietzig T, Bartsch C, Baumann G, Stangl K.
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| Regul Pept 154(1-3):77-84. Epub 2008 Dec 7.PMID: 19101597 2009
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14 | RXFP1
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| Cloning, expression, and functional characterization of relaxin receptor (leucine-rich repeat-containing g protein-coupled receptor 7) splice variants from human fetal membranes.
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| Kern A, Hubbard D, Amano A, Bryant-Greenwood GD.
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| Endocrinology 149(3):1277-94. Epub 2007 Dec 13.PMID: 18079195 2008
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15 | RXFP1
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| Identification of the N-linked glycosylation sites of the human relaxin receptor and effect of glycosylation on receptor function.
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| Yan Y, Scott DJ, Wilkinson TN, Ji J, Tregear GW, Bathgate RA.
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| Biochemistry 47(26):6953-68. Epub 2008 Jun 6.PMID: 18533687 2008
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16 | RXFP1, RXFP2
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| The low-density lipoprotein class A module of the relaxin receptor (leucine-rich repeat containing G-protein coupled receptor 7): its role in signaling and trafficking to the cell membrane.
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| Kern A, Agoulnik AI, Bryant-Greenwood GD.
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| Endocrinology 148(3):1181-94. Epub 2006 Dec 7. 2007
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17 | RXFP1, RXFP2
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| Relaxin family peptide receptors Rxfp1 and Rxfp2: mapping of the mRNA and protein distribution in the reproductive tract of the male rat.
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| Filonzi M, Cardoso LC, Pimenta MT, Queiróz DB, Avellar MC, Porto CS, Lazari MF.
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| Reprod Biol Endocrinol 5:29.PMID: 17623071 2007
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18 | RXFP1, RXFP2
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| Characterization of novel splice variants of LGR7 and LGR8 reveals that receptor signaling is mediated by their unique low density lipoprotein class A modules.
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| Scott DJ, Layfield S, Yan Y, Sudo S, Hsueh AJ, Tregear GW, Bathgate RA.
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| J Biol Chem 281(46):34942-54. Epub 2006 Sep 8. 2006
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19 | RXFP1, RXFP2
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| Characterization of novel splice variants of LGR7 and LGR8 reveals that receptor signaling is mediated by their unique low density lipoprotein class A modules.
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| Scott DJ, Layfield S, Yan Y, Sudo S, Hsueh AJ, Tregear GW, Bathgate RA.
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| J Biol Chem 281(46):34942-54. Epub 2006 Sep 8.
2006
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20 | RXFP1, RXFP2
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| Splice variants of the relaxin and INSL3 receptors reveal unanticipated molecular complexity.
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| Muda M, He C, Martini PG, Ferraro T, Layfield S, Taylor D, Chevrier C, Schweickhardt R, Kelton C, Ryan PL, Bathgate RA.
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| Mol Hum Reprod 11(8):591-600. Epub 2005 Jul 28. 2005
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21 | RLN1, RLN2, RXFP1
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| Increased expression of the relaxin receptor (LGR7) in human endometrium during the secretory phase of the menstrual cycle.
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| Bond CP, Parry LJ, Samuel CS, Gehring HM, Lederman FL, Rogers PA, Summers RJ.
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| J Clin Endocrinol Metab 89(7):3477-85. 2004
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22 | LGR6, RXFP1
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| The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7.
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| Hsu SY, Kudo M, Chen T, Nakabayashi K, Bhalla A, van der Spek PJ, vanDuin M, Hsueh AJ.
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| Mol Endocrinol 14(8):1257-71. 2000
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