Citations for
1RXFP1
Investigation of Interactions at the Extracellular Loops of the Relaxin Family Peptide Receptor 1 (RXFP1).
Diepenhorst NA, Petrie EJ, Chen CZ, Wang A, Hossain MA, Bathgate RA, Gooley PR.
J Biol Chem Biol Chem. 2014 Oct 28. pii: jbc.M114.600882. [Epub ahead of print] 2014
2RXFP1
Identification of small-molecule agonists of human relaxin family receptor 1 (RXFP1) by using a homogenous cell-based cAMP assay.
Chen CZ, Southall N, Xiao J, Marugan JJ, Ferrer M, Hu X, Jones RE, Feng S, Agoulnik IU, Zheng W, Agoulnik AI.
J Biomol Screen 18(6):670-7. doi: 10.1177/1087057112469406. Epub 2012 Dec 4. 2013
3RLN2, RLN3, RXFP1, RXFP2
The relaxin receptor (RXFP1) utilizes hydrophobic moieties on a signaling surface of its N-terminal low density lipoprotein class A module to mediate receptor activation.
Kong RC, Petrie EJ, Mohanty B, Ling J, Lee JC, Gooley PR, Bathgate RA.
J Biol Chem 288(39):28138-51. doi: 10.1074/jbc.M113.499640. Epub 2013 Aug 7. 2013
4RXFP1
Expression of RXFP1 in skin of scleroderma patients and control subjects.
Giordano N, Volpi N, Franci D, Corallo C, Fioravanti A, Papakostas P, Montella A, Biagioli M, Fimiani M, Grasso G, Muscettola MM, Guerranti R, Vannoni D, Galeazzi M, Nuti R.
Scand J Rheumatol 41(5):391-5. doi: 10.3109/03009742.2012.669496. 2012
5RLN1, RLN3, RXFP1, RXFP2
The different ligand-binding modes of relaxin family peptide receptors RXFP1 and RXFP2.
Scott DJ, Rosengren KJ, Bathgate RA.
Mol Endocrinol 26(11):1896-906. doi: 10.1210/me.2012-1188. Epub 2012 Sep 12. 2012
6RLN2, RXFP1, RXFP2
Relaxin 2 is functional at the ocular surface and promotes corneal wound healing.
Hampel U, Klonisch T, Makrantonaki E, Sel S, Schulze U, Garreis F, Seltmann H, Zouboulis CC, Paulsen FP.
Invest Ophthalmol Vis Sci 53(12):7780-90. doi: 10.1167/iovs.12-10714. Erratum in: Invest Ophthalmol Vis Sci. 2014;55(6):3998. Makrantonaki, Eugenia [added 2012
7RXFP1
Endometrial LGR7 expression during menstrual cycle.
Campitiello MR, De Franciscis P, Mele D, Izzo G, Sinisi A, Delrio G, Colacurci N.
Fertil Steril 95(8):2511-4. doi: 10.1016/j.fertnstert.2011.01.124. Epub 2011 Feb 16. 2011
8RLN3, RXFP1
H3 relaxin demonstrates antifibrotic properties via the RXFP1 receptor.
Hossain MA, Man BC, Zhao C, Xu Q, Du XJ, Wade JD, Samuel CS.
Biochemistry 50(8):1368-75. doi: 10.1021/bi1013968. Epub 2011 Jan 31. 2011
9RLN3, RXFP1, RXFP2, RXFP3, RXFP4
Relaxin family peptides in the male reproductive system--a critical appraisal.
Ivell R, Kotula-Balak M, Glynn D, Heng K, Anand-Ivell R.
Mol Hum Reprod 17(2):71-84. doi: 10.1093/molehr/gaq086. Epub 2010 Oct 14. Review. 2011
10RLN1, RXFP1
Relaxin stimulates osteoclast differentiation and activation.
Ferlin A, Pepe A, Facciolli A, Gianesello L, Foresta C.
Bone 46(2):504-13. Epub 2009 Oct 13.PMID: 19833242 2010
11RLN1, RXFP1
Relaxin signaling activates peroxisome proliferator-activated receptor gamma.
Singh S, Bennett RG.
Mol Cell Endocrinol 315(1-2):239-45. Epub 2009 Aug 25.PMID: 19712722 2010
12RXFP1
Characterization of relaxin receptor (RXFP1) desensitization and internalization in primary human decidual cells and RXFP1-transfected HEK293 cells.
Kern A, Bryant-Greenwood GD.
Endocrinology 150(5):2419-28. Epub 2008 Dec 30.PMID: 19116340 2009
13RXFP1
RXFP1-inactive relaxin activates human glucocorticoid receptor: further investigations into the relaxin-GR pathway.
Dschietzig T, Bartsch C, Baumann G, Stangl K.
Regul Pept 154(1-3):77-84. Epub 2008 Dec 7.PMID: 19101597 2009
14RXFP1
Cloning, expression, and functional characterization of relaxin receptor (leucine-rich repeat-containing g protein-coupled receptor 7) splice variants from human fetal membranes.
Kern A, Hubbard D, Amano A, Bryant-Greenwood GD.
Endocrinology 149(3):1277-94. Epub 2007 Dec 13.PMID: 18079195 2008
15RXFP1
Identification of the N-linked glycosylation sites of the human relaxin receptor and effect of glycosylation on receptor function.
Yan Y, Scott DJ, Wilkinson TN, Ji J, Tregear GW, Bathgate RA.
Biochemistry 47(26):6953-68. Epub 2008 Jun 6.PMID: 18533687 2008
16RXFP1, RXFP2
The low-density lipoprotein class A module of the relaxin receptor (leucine-rich repeat containing G-protein coupled receptor 7): its role in signaling and trafficking to the cell membrane.
Kern A, Agoulnik AI, Bryant-Greenwood GD.
Endocrinology 148(3):1181-94. Epub 2006 Dec 7. 2007
17RXFP1, RXFP2
Relaxin family peptide receptors Rxfp1 and Rxfp2: mapping of the mRNA and protein distribution in the reproductive tract of the male rat.
Filonzi M, Cardoso LC, Pimenta MT, Queiróz DB, Avellar MC, Porto CS, Lazari MF.
Reprod Biol Endocrinol 5:29.PMID: 17623071 2007
18RXFP1, RXFP2
Characterization of novel splice variants of LGR7 and LGR8 reveals that receptor signaling is mediated by their unique low density lipoprotein class A modules.
Scott DJ, Layfield S, Yan Y, Sudo S, Hsueh AJ, Tregear GW, Bathgate RA.
J Biol Chem 281(46):34942-54. Epub 2006 Sep 8. 2006
19RXFP1, RXFP2
Characterization of novel splice variants of LGR7 and LGR8 reveals that receptor signaling is mediated by their unique low density lipoprotein class A modules.
Scott DJ, Layfield S, Yan Y, Sudo S, Hsueh AJ, Tregear GW, Bathgate RA.
J Biol Chem 281(46):34942-54. Epub 2006 Sep 8. 2006
20RXFP1, RXFP2
Splice variants of the relaxin and INSL3 receptors reveal unanticipated molecular complexity.
Muda M, He C, Martini PG, Ferraro T, Layfield S, Taylor D, Chevrier C, Schweickhardt R, Kelton C, Ryan PL, Bathgate RA.
Mol Hum Reprod 11(8):591-600. Epub 2005 Jul 28. 2005
21RLN1, RLN2, RXFP1
Increased expression of the relaxin receptor (LGR7) in human endometrium during the secretory phase of the menstrual cycle.
Bond CP, Parry LJ, Samuel CS, Gehring HM, Lederman FL, Rogers PA, Summers RJ.
J Clin Endocrinol Metab 89(7):3477-85. 2004
22LGR6, RXFP1
The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7.
Hsu SY, Kudo M, Chen T, Nakabayashi K, Bhalla A, van der Spek PJ, vanDuin M, Hsueh AJ.
Mol Endocrinol 14(8):1257-71. 2000