| 1 | ATF4, RUNX2, SP7
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| Regulation and Role of Transcription Factors in Osteogenesis.
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| Chan WCW, Tan Z, To MKT, Chan D.
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| Int J Mol Sci. May 21;22(11):5445. doi: 10.3390/ijms22115445. 2021
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| 2 | CBFB, IHH, RUNX2, SP7
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| Molecular Mechanism of Runx2-Dependent Bone Development.
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| Komori T.
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| Mol Cells. Feb 29;43(2):168-175. doi: 10.14348/molcells.2019.0244 2020
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| 3 | LEF1, RUNX2, WNT3, WWTR1
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| Interaction of LEF1 with TAZ is necessary for the osteoblastogenic activity of Wnt3a.
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| Kida J, Hata K, Nakamura E, Yagi H, Takahata Y, Murakami T, Maeda Y, Nishimura R.
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| Sci Rep 8(1):10375. doi: 10.1038/s41598-018-28711-4.
2018
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| 4 | NFIC, RUNX2, SP7
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| The Nfic-osterix pathway regulates ameloblast differentiation and enamel formation
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| Lee DS, Roh SY, Park JC.
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| Cell Tissue Res. Dec;374(3):531-540. doi: 10.1007/s00441-018-2901-3. Epub 2018 Aug 9 2018
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| 5 | CAMK2N1, RUNX2
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| RUNX3 and CAMK2N1 hypermethylation as prognostic marker for epithelial ovarian cancer.
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| Häfner N, Steinbach D, Jansen L, Diebolder H, Dürst M, Runnebaum IB.
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| Int J Cancer 138(1):217-28. doi: 10.1002/ijc.29690.
2016
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| 6 | IPO8, RUNX2
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| RUNX2 controls human IPO8 basal transcription in Saos-2 cells
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| Xiong J, Hu Z, Wang T, Xu X, Liu J, Wu P, Che X, Li W.
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| Mol Med Rep. Aug;14(2):1418-24. doi: 10.3892/mmr.2016.5356. Epub 2016 Jun 1 2016
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| 7 | RUNX2, SOX6
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| Functional analyses reveal the essential role of SOX6 and RUNX2 in the communication of chondrocyte and osteoblast.
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| Zhang Y, Yang TL, Li X, Guo Y.
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| Osteoporos Int 26(2):553-61. doi: 10.1007/s00198-014-2882-3. Epub 2014 Sep 12.
2015
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| 8 | KDM6B, RUNX2
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| JMJD3 promotes chondrocyte proliferation and hypertrophy during endochondral bone formation in mice.
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| Zhang F, Xu L, Xu L, Xu Q, Li D, Yang Y, Karsenty G, Chen CD.
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| J Mol Cell Biol 7(1):23-34. doi: 10.1093/jmcb/mjv003. Epub 2015 Jan 13.
2015
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| 9 | CTNNB1, HDAC7, RUNX2
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| Histone deacetylase 7 (Hdac7) suppresses chondrocyte proliferation and β-catenin activity during endochondral ossification.
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| Bradley EW, Carpio LR, Olson EN, Westendorf JJ.
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| J Biol Chem 290(1):118-26. doi: 10.1074/jbc.M114.596247. Epub 2014 Nov 11. 2015
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| 10 | RUNX2, WNT1
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| Crucial roles of canonical Runx2-dependent pathway on Wnt1-induced osteoblastic differentiation of human periodontal ligament fibroblasts.
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| Kook SH, Heo JS, Lee JC.
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| Mol Cell Biochem 402(1-2):213-23. doi: 10.1007/s11010-015-2329-y.
2015
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| 11 | RUNX2, SP7
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| Sp7 and Runx2 molecular complex synergistically regulate expression of target genes.
|
| Rashid H, Ma C, Chen H, Wang H, Hassan MQ, Sinha K, de Crombrugghe B, Javed A.
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| Connect Tissue Res 55 Suppl 1:83-7. doi: 10.3109/03008207.2014.923872.
2014
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| 12 | RUNX2, SMURF1
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| A feedback loop between RUNX2 and the E3 ligase SMURF1 in regulation of differentiation of human dental pulp stem cells.
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| Yang F, Xu N, Li D, Guan L, He Y, Zhang Y, Lu Q, Zhang X.
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| J Endod 40(10):1579-86. doi: 10.1016/j.joen.2014.04.010. Epub 2014 Jun 11.
2014
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| 13 | RUNX2, SMURF1
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| A feedback loop between RUNX2 and the E3 ligase SMURF1 in regulation of differentiation of human dental pulp stem cells.
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| Yang F, Xu N, Li D, Guan L, He Y, Zhang Y, Lu Q, Zhang X.
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| J Endod 40(10):1579-86. doi: 10.1016/j.joen.2014.04.010. Epub 2014 Jun 11.
2014
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| 14 | NAA10, RUNX2
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| NAA10 controls osteoblast differentiation and bone formation as a feedback regulator of Runx2.
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| Yoon H, Kim HL, Chun YS, Shin DH, Lee KH, Shin CS, Lee DY, Kim HH, Lee ZH, Ryoo HM, Lee MN, Oh GT, Park JW.
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| Nat Commun 5:5176. doi: 10.1038/ncomms6176.
2014
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| 15 | MAP2K5, MAPK7, RUNX2
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| The MEK5/ERK5 pathway mediates fluid shear stress promoted osteoblast differentiation.
|
| Zhao LG, Chen SL, Teng YJ, An LP, Wang J, Ma JL, Xia YY.
|
| Connect Tissue Res 55(2):96-102. doi: 10.3109/03008207.2013.853755. Epub 2014 Jan 10.
2014
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| 16 | DUP6PM, RUNX2
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| Pure de novo partial trisomy 6p in a girl with craniosynostosis.
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| Varvagiannis K, Stefanidou A, Gyftodimou Y, Lord H, Williams L, Sarri C, Pandelia E, Bazopoulou-Kyrkanidou E, Noakes C, Lester T, Wilkie AO, Petersen MB.
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| Am J Med Genet A m J Med Genet A. 2013 Jan 10. doi: 10.1002/ajmg.a.35727. [Epub ahead of print]
2013
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| 17 | KAT2B, RUNX2
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| PCAF acetylates Runx2 and promotes osteoblast differentiation.
|
| Wang CY, Yang SF, Wang Z, Tan JM, Xing SM, Chen DC, Xu SM, Yuan W.
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| J Bone Miner Metab Bone Miner Metab. 2013 Mar 7. [Epub ahead of print]
2013
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| 18 | DLX5, GATA4, RUNX2
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| GATA4 negatively regulates osteoblast differentiation by downregulation of Runx2.
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| Song I, Kim K, Kim JH, Lee YK, Jung HJ, Byun HO, Yoon G, Kim N.
|
| BMB Rep MB Rep. 2013 Dec 22. pii: 2539. [Epub ahead of print]
2013
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| 19 | BGLAP, IBSP, KDM6B, RUNX2, SP7
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| Histone demethylase Jmjd3 regulates osteoblast differentiation via transcription factors Runx2 and osterix.
|
| Yang D, Okamura H, Nakashima Y, Haneji T.
|
| J Biol Chem 288(47):33530-41. doi: 10.1074/jbc.M113.497040. Epub 2013 Oct 8.
2013
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| 20 | RUNX2, TSSC1
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| Runx2 induces bone osteolysis by transcriptional suppression of TSSC1.
|
| Wang DC, Wang HF, Yuan ZN.
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| Biochem Biophys Res Commun 438(4):635-9. doi: 10.1016/j.bbrc.2013.07.131. Epub 2013 Aug 8.
2013
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| 21 | CBL, RUNX2, STAT5A
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| Promotion of osteoblast differentiation in mesenchymal cells through Cbl-mediated control of STAT5 activity.
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| Dieudonne FX, Sévère N, Biosse-Duplan M, Weng JJ, Su Y, Marie PJ.
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| Stem Cells 31(7):1340-9. doi: 10.1002/stem.1380.
2013
|
| 22 | AXIN2, HDAC3, RUNX2
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| Runx2 protein represses Axin2 expression in osteoblasts and is required for craniosynostosis in Axin2-deficient mice.
|
| McGee-Lawrence ME, Li X, Bledsoe KL, Wu H, Hawse JR, Subramaniam M, Razidlo DF, Stensgard BA, Stein GS, van Wijnen AJ, Lian JB, Hsu W, Westendorf JJ.
|
| J Biol Chem 288(8):5291-302. doi: 10.1074/jbc.M112.414995. Epub 2013 Jan 7.
2013
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| 23 | ALCAM, RUNX2
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| Hierarchical organization of osteoblasts reveals the significant role of CD166 in hematopoietic stem cell maintenance and function.
|
| Chitteti BR, Cheng YH, Kacena MA, Srour EF.
|
| Bone 54(1):58-67. doi: 10.1016/j.bone.2013.01.038. Epub 2013 Jan 28.
2013
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| 24 | DCLK1, RUNX2
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| The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2.
|
| Zou W, Greenblatt MB, Brady N, Lotinun S, Zhai B, de Rivera H, Singh A, Sun J, Gygi SP, Baron R, Glimcher LH, Jones DC.
|
| J Exp Med 210(9):1793-806. doi: 10.1084/jem.20111790. Epub 2013 Aug 5.
2013
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| 25 | RUNX2, RUNX3
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| Functional role of Runx3 in the regulation of aggrecan expression during cartilage development.
|
| Wigner NA, Soung do Y, Einhorn TA, Drissi H, Gerstenfeld LC.
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| J Cell Physiol 228(11):2232-42. doi: 10.1002/jcp.24396.
2013
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| 26 | RUNX2, S100A16
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| S100A16 inhibits osteogenesis but stimulates adipogenesis.
|
| Li D, Zhang R, Zhu W, Xue Y, Zhang Y, Huang Q, Liu M, Liu Y.
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| Mol Biol Rep 40(5):3465-73. doi: 10.1007/s11033-012-2413-2. Epub 2013 Mar 25.
2013
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| 27 | ATF6, RUNX2, XBP1
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| XBP1S associates with RUNX2 and regulates chondrocyte hypertrophy.
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| Liu Y, Zhou J, Zhao W, Li X, Jiang R, Liu C, Guo FJ.
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| J Biol Chem 287(41):34500-13. doi: 10.1074/jbc.M112.385922. Epub 2012 Aug 3. Retraction in: J Biol Chem. 2015 Apr 24;290(17):10643.
2012
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| 28 | CEBPB, EPAS1, MMP13, RUNX2
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| C/EBPB and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2á as the inducer in chondrocytes.
|
| Hirata M, Kugimiya F, Fukai A, Saito T, Yano F, Ikeda T, Mabuchi A, Sapkota BR, Akune T, Nishida N, Yoshimura N, Nakagawa T, Tokunaga K, Nakamura K, Chung UI, Kawaguchi H.
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| Hum Mol Genet 21(5):1111-23. doi: 10.1093/hmg/ddr540. Epub 2011 Nov 17. 2012
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| 29 | MMP13, RUNX2, SP7
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| Osterix regulates calcification and degradation of chondrogenic matrices through matrix metalloproteinase 13 (MMP13) expression in association with transcription factor Runx2 during endochondral ossification.
|
| Nishimura R, Wakabayashi M, Hata K, Matsubara T, Honma S, Wakisaka S, Kiyonari H, Shioi G, Yamaguchi A, Tsumaki N, Akiyama H, Yoneda T.
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| J Biol Chem 287(40):33179-90. Epub 2012 Aug 6.
2012
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| 30 | RUNX2, SRF
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| Serum response factor regulates bone formation via IGF-1 and Runx2 signals.
|
| Chen J, Yuan K, Mao X, Miano JM, Wu H, Chen Y.
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| J Bone Miner Res 27(8):1659-68. doi: 10.1002/jbmr.1607.
2012
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| 31 | EHMT2, RUNX2
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| Recruitment of coregulator G9a by Runx2 for selective enhancement or suppression of transcription.
|
| Purcell DJ, Khalid O, Ou CY, Little GH, Frenkel B, Baniwal SK, Stallcup MR.
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| J Cell Biochem 113(7):2406-14. doi: 10.1002/jcb.24114.
2012
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| 32 | HIF1A, RUNX2, VEGFA
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| Runx2 protein stabilizes hypoxia-inducible factor-1α through competition with von Hippel-Lindau protein (pVHL) and stimulates angiogenesis in growth plate hypertrophic chondrocytes.
|
| Lee SH, Che X, Jeong JH, Choi JY, Lee YJ, Lee YH, Bae SC, Lee YM.
|
| J Biol Chem 287(18):14760-71. doi: 10.1074/jbc.M112.340232. Epub 2012 Feb 20.
2012
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| 33 | RUNX2
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| Biomechanical stimulation of osteoblast gene expression requires phosphorylation of the RUNX2 transcription factor.
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| Li Y, Ge C, Long JP, Begun DL, Rodriguez JA, Goldstein SA, Franceschi RT.
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| J Bone Miner Res 27(6):1263-74. doi: 10.1002/jbmr.1574.
2012
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| 34 | RUNX2
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| Targeting Runx2 expression in hypertrophic chondrocytes impairs endochondral ossification during early skeletal development.
|
| Ding M, Lu Y, Abbassi S, Li F, Li X, Song Y, Geoffroy V, Im HJ, Zheng Q.
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| J Cell Physiol 227(10):3446-56. doi: 10.1002/jcp.24045.
2012
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| 35 | RUNX2
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| Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility.
|
| van der Deen M, Akech J, Lapointe D, Gupta S, Young DW, Montecino MA, Galindo M, Lian JB, Stein JL, Stein GS, van Wijnen AJ.
|
| J Biol Chem 287(7):4503-17. doi: 10.1074/jbc.M111.287771. Epub 2011 Dec 9.
2012
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| 36 | HTR2A, HTR2B, HTR2C, PTHLH, RUNX2
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| Mammary gland serotonin regulates parathyroid hormone-related protein and other bone-related signals.
|
| Hernandez LL, Gregerson KA, Horseman ND.
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| Am J Physiol Endocrinol Metab 302(8):E1009-15. doi: 10.1152/ajpendo.00666.2011. Epub 2012 Feb 7.
2012
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| 37 | ATF6, BGLAP, BMP2, RUNX2
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| BMP2 protein regulates osteocalcin expression via Runx2-mediated Atf6 gene transcription.
|
| Jang WG, Kim EJ, Kim DK, Ryoo HM, Lee KB, Kim SH, Choi HS, Koh JT.
|
| J Biol Chem 287(2):905-15. doi: 10.1074/jbc.M111.253187. Epub 2011 Nov 18.
2012
|
| 38 | NELL1, RUNX2, SOX9
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| Calvarial cleidocraniodysplasia-like defects with ENU-induced Nell-1 deficiency.
|
| Zhang X, Ting K, Pathmanathan D, Ko T, Chen W, Chen F, Lee H, James AW, Siu RK, Shen J, Culiat CT, Soo C.
|
| J Craniofac Surg 23(1):61-6. doi: 10.1097/SCS.0b013e318240c8c4.
2012
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| 39 | PIP, RUNX2
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| Runx2 controls a feed-forward loop between androgen and prolactin-induced protein (PIP) in stimulating T47D cell proliferation.
|
| Baniwal SK, Little GH, Chimge NO, Frenkel B.
|
| J Cell Physiol 227(5):2276-82. doi: 10.1002/jcp.22966.
2012
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| 40 | FOXO1, RUNX2
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| FOXO1 inhibits Runx2 transcriptional activity and prostate cancer cell migration and invasion.
|
| Zhang H, Pan Y, Zheng L, Choe C, Lindgren B, Jensen ED, Westendorf JJ, Cheng L, Huang H.
|
| Cancer Res 71(9):3257-67. Epub 2011 Apr 19.
2011
|
| 41 | RUNX2
|
| The role of runt-related transcription factor 2 (Runx2) in the late stage of odontoblast differentiation and dentin formation.
|
| Li S, Kong H, Yao N, Yu Q, Wang P, Lin Y, Wang J, Kuang R, Zhao X, Xu J, Zhu Q, Ni L.
|
| Biochem Biophys Res Commun 410(3):698-704. Epub 2011 Jun 15.
2011
|
| 42 | BMP2, RUNX2
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| Bone morphogenetic protein-2 activates NADPH oxidase to increase endoplasmic reticulum stress and human coronary artery smooth muscle cell calcification.
|
| Liberman M, Johnson RC, Handy DE, Loscalzo J, Leopold JA.
|
| Biochem Biophys Res Commun 413(3):436-41. Epub 2011 Aug 30.
2011
|
| 43 | PANX3, RUNX2
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| Pannexin 3 is a novel target for Runx2, expressed by osteoblasts and mature growth plate chondrocytes.
|
| Bond SR, Lau A, Penuela S, Sampaio AV, Underhill TM, Laird DW, Naus CC.
|
| J Bone Miner Res 26(12):2911-22. doi: 10.1002/jbmr.509.
2011
|
| 44 | COL10A1, RUNX2
|
| Runx2 contributes to murine Col10a1 gene regulation through direct interaction with its cis-enhancer.
|
| Li F, Lu Y, Ding M, Napierala D, Abbassi S, Chen Y, Duan X, Wang S, Lee B, Zheng Q.
|
| J Bone Miner Res 26(12):2899-910. doi: 10.1002/jbmr.504.
2011
|
| 45 | RUNX2
|
| Early onset of Runx2 expression caused craniosynostosis, ectopic bone formation, and limb defects.
|
| Maeno T, Moriishi T, Yoshida CA, Komori H, Kanatani N, Izumi S, Takaoka K, Komori T.
|
| Bone 49(4):673-82. doi: 10.1016/j.bone.2011.07.023. Epub 2011 Jul 23.
2011
|
| 46 | HMGB2, LEF1, RUNX2
|
| Expression patterns and function of chromatin protein HMGB2 during mesenchymal stem cell differentiation.
|
| Taniguchi N, Caramés B, Hsu E, Cherqui S, Kawakami Y, Lotz M.
|
| J Biol Chem 286(48):41489-98. doi: 10.1074/jbc.M111.236984. Epub 2011 Sep 2.
2011
|
| 47 | NKX3-2, RUNX2
|
| Nkx3.2-induced suppression of Runx2 is a crucial mediator of hypoxia-dependent maintenance of chondrocyte phenotypes.
|
| Kawato Y, Hirao M, Ebina K, Tamai N, Shi K, Hashimoto J, Yoshikawa H, Myoui A.
|
| Biochem Biophys Res Commun 416(1-2):205-10. doi: 10.1016/j.bbrc.2011.11.026. Epub 2011 Nov 10.
2011
|
| 48 | NKX2-1, RUNX2
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| Thyroid-specific gene expression in chondrocytes.
|
| Endo T, Kobayashi T.
|
| Biochem Biophys Res Commun 416(3-4):227-31. doi: 10.1016/j.bbrc.2011.08.122. Epub 2011 Sep 16.
2011
|
| 49 | FGF2, RUNX2
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| Fibroblast growth factor-2 induces osteogenic differentiation through a Runx2 activation in vascular smooth muscle cells.
|
| Nakahara T, Sato H, Shimizu T, Tanaka T, Matsui H, Kawai-Kowase K, Sato M, Iso T, Arai M, Kurabayashi M.
|
| Biochem Biophys Res Commun 394(2):243-8. Epub 2009 Nov 10.
2010
|
| 50 | RUNX2, TLE1, UBTF
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| Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes.
|
| Ali SA, Zaidi SK, Dobson JR, Shakoori AR, Lian JB, Stein JL, van Wijnen AJ, Stein GS.
|
| Proc Natl Acad Sci U S A 107(9):4165-9. Epub 2010 Feb 16. 2010
|
| 51 | RUNX2
|
| Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions.
|
| Akech J, Wixted JJ, Bedard K, van der Deen M, Hussain S, Guise TA, van Wijnen AJ, Stein JL, Languino LR, Altieri DC, Pratap J, Keller E, Stein GS, Lian JB.
|
| Oncogene 29(6):811-21. Epub 2009 Nov 16.
2010
|
| 52 | RUNX2
|
| FGF2-activated ERK mitogen-activated protein kinase enhances Runx2 acetylation and stabilization.
|
| Park OJ, Kim HJ, Woo KM, Baek JH, Ryoo HM.
|
| J Biol Chem 285(6):3568-74. Epub 2009 Dec 10.
2010
|
| 53 | RUNX2
|
| Runx2 regulates survivin expression in prostate cancer cells.
|
| Lim M, Zhong C, Yang S, Bell AM, Cohen MB, Roy-Burman P.
|
| Lab Invest 90(2):222-33. Epub 2009 Nov 30.
2010
|
| 54 | RUNX2
|
| Regulation of bone development and extracellular matrix protein genes by RUNX2.
|
| Komori T.
|
| Cell Tissue Res 339(1):189-95. Epub 2009 Aug 1. Review.
2010
|
| 55 | CCD, RUNX2
|
| Severe cleidocranial dysplasia and hypophosphatasia in a child with microdeletion of the C-terminal region of RUNX2.
|
| El-Gharbawy AH, Peeden JN Jr, Lachman RS, Graham JM Jr, Moore SR, Rimoin DL.
|
| Am J Med Genet A 152A(1):169-74.PMID: 20014132 2010
|
| 56 | RUNX2
|
| Copy number variation analysis in single-suture craniosynostosis: Multiple rare variants including RUNX2 duplication in two cousins with metopic craniosynostosis.
|
| Mefford HC, Shafer N, Antonacci F, Tsai JM, Park SS, Hing AV, Rieder MJ, Smyth MD, Speltz ML, Eichler EE, Cunningham ML.
|
| Am J Med Genet A 152A(9):2203-10.PMID: 20683987 2010
|
| 57 | HES1, HES2, ID4, RUNX2
|
| Id4, a new candidate gene for senile osteoporosis, acts as a molecular switch promoting osteoblast differentiation.
|
| Tokuzawa Y, Yagi K, Yamashita Y, Nakachi Y, Nikaido I, Bono H, Ninomiya Y, Kanesaki-Yatsuka Y, Akita M, Motegi H, Wakana S, Noda T, Sablitzky F, Arai S, Kurokawa R, Fukuda T, Katagiri T, Schönbach C, Suda T, Mizuno Y, Okazaki Y.
|
| PLoS Genet 6(7):e1001019.PMID: 20628571 2010
|
| 58 | ARID4A, RUNX2
|
| Retinoblastoma binding protein-1 (RBP1) is a Runx2 coactivator and promotes osteoblastic differentiation.
|
| Monroe DG, Hawse JR, Subramaniam M, Spelsberg TC.
|
| BMC Musculoskelet Disord 11:104.PMID: 20509905 2010
|
| 59 | MMP20, ODAM, RUNX2
|
| The odontogenic ameloblast-associated protein (ODAM) cooperates with RUNX2 and modulates enamel mineralization via regulation of MMP-20.
|
| Lee HK, Lee DS, Ryoo HM, Park JT, Park SJ, Bae HS, Cho MI, Park JC.
|
| J Cell Biochem 111(3):755-67.
2010
|
| 60 | FOXO1, RUNX2
|
| Foxo1, a novel regulator of osteoblast differentiation and skeletogenesis.
|
| Teixeira CC, Liu Y, Thant LM, Pang J, Palmer G, Alikhani M.
|
| J Biol Chem 285(40):31055-65. Epub 2010 Jul 22.
2010
|
| 61 | RUNX2, ZNF521
|
| Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity.
|
| Hesse E, Saito H, Kiviranta R, Correa D, Yamana K, Neff L, Toben D, Duda G, Atfi A, Geoffroy V, Horne WC, Baron R.
|
| J Cell Biol 191(7):1271-83. Epub 2010 Dec 20.
2010
|
| 62 | HDAC7, RUNX2
|
| Bone morphogenic protein 2 activates protein kinase D to regulate histone deacetylase 7 localization and repression of Runx2.
|
| Jensen ED, Gopalakrishnan R, Westendorf JJ.
|
| J Biol Chem 284(4):2225-34. Epub 2008 Nov 21. 2009
|
| 63 | RUNX2, SNAI1
|
| Snail1 controls bone mass by regulating Runx2 and VDR expression during osteoblast differentiation.
|
| de Frutos CA, Dacquin R, Vega S, Jurdic P, Machuca-Gayet I, Nieto MA.
|
| EMBO J 28(6):686-96. Epub 2009 Feb 5.
2009
|
| 64 | CCD, RUNX2
|
| A Runx2 threshold for the cleidocranial dysplasia phenotype.
|
| Lou Y, Javed A, Hussain S, Colby J, Frederick D, Pratap J, Xie R, Gaur T, van Wijnen AJ, Jones SN, Stein GS, Lian JB, Stein JL.
|
| Hum Mol Genet 18(3):556-68. Epub 2008 Nov 20.
2009
|
| 65 | MMP13, PTH, RUNX2
|
| Identification and characterization of Runx2 phosphorylation sites involved in matrix metalloproteinase-13 promoter activation.
|
| Selvamurugan N, Shimizu E, Lee M, Liu T, Li H, Partridge NC.
|
| FEBS Lett 583(7):1141-6. Epub 2009 Mar 3.
2009
|
| 66 | HDAC4, RUNX2, VEGFA
|
| HDAC4 represses vascular endothelial growth factor expression in chondrosarcoma by modulating RUNX2 activity.
|
| Sun X, Wei L, Chen Q, Terek RM.
|
| J Biol Chem 284(33):21881-90. Epub 2009 Jun 9.PMID: 19509297 2009
|
| 67 | FGF8, RUNX2
|
| FGF8 regulates myogenesis and induces Runx2 expression and osteoblast differentiation in cultured cells.
|
| Omoteyama K, Takagi M.
|
| J Cell Biochem 106(4):546-52.PMID: 19170063 2009
|
| 68 | DSPP, RUNX2, SP7
|
| Runx2, osx, and dspp in tooth development.
|
| Chen S, Gluhak-Heinrich J, Wang YH, Wu YM, Chuang HH, Chen L, Yuan GH, Dong J, Gay I, MacDougall M.
|
| J Dent Res 88(10):904-9.
2009
|
| 69 | CCD, RUNX2
|
| De novo three-way chromosome translocation 46,XY,t(4;6;21)(p16;p21.1;q21) in a male with cleidocranial dysplasia.
|
| Purandare SM, Mendoza-Londono R, Yatsenko SA, Napierala D, Scott DA, Sibai T, Casas K, Wilson P, Lee J, Muneer R, Leonard JC, Ramji FG, Lachman R, Li S, Stankiewicz P, Lee B, Mulvihill JJ.
|
| Am J Med Genet A 146(4):453-8. 2008
|
| 70 | RUNX2, SP7
|
| Upregulation of Runx2 and Osterix during in vitro chondrogenesis of human adipose-derived stromal cells.
|
| Rich JT, Rosov‡ I, Nolta JA, Myckatyn TM, Sandell LJ, McAlinden A.
|
| Biochem Biophys Res Commun 372(1):230-5. Epub 2008 May 13. 2008
|
| 71 | RUNX2, TRPS1
|
| Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome.
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| Napierala D, Sam K, Morello R, Zheng Q, Munivez E, Shivdasani RA, Lee B.
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| Hum Mol Genet 17(14):2244-54. Epub 2008 Apr 17.
2008
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| 72 | AIRE, ATR, BCOR, CCD, COL1A1, COL1A2, CRDAI, CYP27B1, DLX", FTC1, GALNT3, HPC3, NHS, OFCD, OI1A, OI1B, PCNT, PDDR, PGA1, RUNX2, SCKL, SCKL1, SCKL2, SCKL3, SHH, SIOD, SMARCAL1, TDOS, VDDR2, VDR, WHS
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| The genetic basis of inherited anomalies of the teeth. Part 2: syndromes with significant dental involvement.
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| Bailleul-Forestier I, Berdal A, Vinckier F, de Ravel T, Fryns JP, Verloes A.
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| Eur J Med Genet 51(5):383-408. Epub 2008 May 23. Review. 2008
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| 73 | GPER1, RGS2, RUNX2
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| Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors.
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| Teplyuk NM, Galindo M, Teplyuk VI, Pratap J, Young DW, Lapointe D, Javed A, Stein JL, Lian JB, Stein GS, van Wijnen AJ.
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| J Biol Chem 283(41):27585-97. Epub 2008 Jul 14. 2008
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| 74 | RUNX2, SP7
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| BMP2 regulates Osterix through Msx2 and Runx2 during osteoblast differentiation.
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| Matsubara T, Kida K, Yamaguchi A, Hata K, Ichida F, Meguro H, Aburatani H, Nishimura R, Yoneda T.
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| J Biol Chem 283(43):29119-25. Epub 2008 Aug 14.
2008
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| 75 | NELL1, RUNX2
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| Involvement of MAPK signaling molecules and Runx2 in the NELL1-induced osteoblastic differentiation.
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| Bokui N, Otani T, Igarashi K, Kaku J, Oda M, Nagaoka T, Seno M, Tatematsu K, Okajima T, Matsuzaki T, Ting K, Tanizawa K, Kuroda S.
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| FEBS Lett 582(2):365-71. Epub 2007 Dec 17.PMID: 18082140 2008
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| 76 | RUNX2
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| Runx2 represses myocardin-mediated differentiation and facilitates osteogenic conversion of vascular smooth muscle cells.
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| Tanaka T, Sato H, Doi H, Yoshida CA, Shimizu T, Matsui H, Yamazaki M, Akiyama H, Kawai-Kowase K, Iso T, Komori T, Arai M, Kurabayashi M.
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| Mol Cell Biol 28(3):1147-60. Epub 2007 Nov 26.PMID: 18039851 2008
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| 77 | RUNX1, RUNX2, RUNX3, STAT5B
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| Physical and functional interactions between STAT5 and Runx transcription factors.
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| Ogawa S, Satake M, Ikuta K.
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| J Biochem 143(5):695-709. Epub 2008 Feb 22.PMID: 18296717 2008
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| 78 | RUNX1, RUNX2, CCD, FPDAML
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| Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles.
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| Matheny CJ, Speck ME, Cushing PR, Zhou Y, Corpora T, Regan M, Newman M, Roudaia L, Speck CL, Gu TL, Griffey SM, Bushweller JH, Speck NA.
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| EMBO J 26(4):1163-75. Epub 2007 Feb 8. 2007
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| 79 | NELL1, RUNX2
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| Craniosynostosis-associated gene nell-1 is regulated by runx2.
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| Truong T, Zhang X, Pathmanathan D, Soo C, Ting K.
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| J Bone Miner Res 22(1):7-18. 2007
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| 80 | NFATC2, RUNX2
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| Regulation of NFATc2 gene expression by the transcription factor Runx2.
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| Thirunavukkarasu K, Pei Y, Moore TL, Wei T, Wang H, Chandrasekhar S.
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| Mol Biol Rep 34(1):1-10. Epub 2006 Nov 11.
2007
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| 81 | RUNX2
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| Mitotic control of RUNX2 phosphorylation by both CDK1/cyclin B kinase and PP1/PP2A phosphatase in osteoblastic cells.
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| Rajgopal A, Young DW, Mujeeb KA, Stein JL, Lian JB, van Wijnen AJ, Stein GS.
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| J Cell Biochem 100(6):1509-17. 2007
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| 82 | CCD, RUNX2
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| A novel mutation of gene CBFA1/RUNX2 in cleidocranial dysplasia.
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| Lo Muzio L, Tetè S, Mastrangelo F, Cazzolla AP, Lacaita MG, Margaglione M, Campisi G.
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| Ann Clin Lab Sci 37(2):115-20.
2007
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| 83 | RUNX1, RUNX2, RUNX3
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| Runx3/AML2/Cbfa3 regulates early and late chondrocyte differentiation.
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| Soung do Y, Dong Y, Wang Y, Zuscik MJ, Schwarz EM, O'Keefe RJ, Drissi H.
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| J Bone Miner Res 22(8):1260-70.
2007
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| 84 | FLNB, RUNX2
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| Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner.
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| Zheng L, Baek HJ, Karsenty G, Justice MJ.
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| J Cell Biol 178(1):121-8.
2007
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| 85 | RUNX2, TRAM2
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| Identification of novel Runx2 targets in osteoblasts: cell type-specific BMP-dependent regulation of Tram2.
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| Pregizer S, Barski A, Gersbach CA, García AJ, Frenkel B.
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| J Cell Biochem 102(6):1458-71.PMID: 17486635 2007
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| 86 | RUNX2
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| Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential.
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| Zaidi SK, Pande S, Pratap J, Gaur T, Grigoriu S, Ali SA, Stein JL, Lian JB, van Wijnen AJ, Stein GS.
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| Proc Natl Acad Sci U S A 104(50):19861-6. Epub 2007 Dec 5.
2007
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| 87 | FGF18, RUNX2
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| Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium.
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| Hinoi E, Bialek P, Chen YT, Rached MT, Groner Y, Behringer RR, Ornitz DM, Karsenty G.
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| Genes Dev 20(21):2937-42. Epub 2006 Oct 18.
2006
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| 88 | CMPD1, RUNX2, SOX9
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| Dominance of SOX9 function over RUNX2 during skeletogenesis.
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| Zhou G, Zheng Q, Engin F, Munivez E, Chen Y, Sebald E, Krakow D, Lee B.
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| Proc Natl Acad Sci U S A 103(50):19004-9. Epub 2006 Dec 1. 2006
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| 89 | RUNX2
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| Cbfa-1 (Runx-2) and osteocalcin expression by human osteoblasts in heparin osteoporosis in vitro.
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| Handschin AE, Egermann M, Trentz O, Wanner GA, Kock HJ, Zund G, Trentz OA.
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| Clin Appl Thromb Hemost 12(4):465-72. 2006
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| 90 | TGFB1, TGFBR1, RUNX2
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| Repetitive exposure to TGF-beta suppresses TGF-beta type I receptor expression by differentiated osteoblasts.
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| Kim KK, Ji C, Chang W, Wells RG, Gundberg CM, McCarthy TL, Centrella M.
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| Gene 379:175-84. Epub 2006 May 19. 2006
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| 91 | RUNX2
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| Four novel RUNX2 mutations including a splice donor site result in the cleidocranial dysplasia phenotype.
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| Kim HJ, Nam SH, Kim HJ, Park HS, Ryoo HM, Kim SY, Cho TJ, Kim SG, Bae SC, Kim IS, Stein JL, van Wijnen AJ, Stein GS, Lian JB, Choi JY.
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| J Cell Physiol 207(1):114-22. 2006
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| 92 | BMP4, RUNX2
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| Different roles of Runx2 during early neural crest-derived bone and tooth development.
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| James MJ, JŠrvinen E, Wang XP, Thesleff I.
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| J Bone Miner Res 21(7):1034-44. 2006
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| 93 | RUNX2, SMAD6, SMURF1
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| Smad6 interacts with Runx2 and mediates Smad ubiquitin regulatory factor 1-induced Runx2 degradation.
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| Shen R, Chen M, Wang YJ, Kaneki H, Xing L, O'keefe RJ, Chen D.
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| J Biol Chem 281(6):3569-76. Epub 2005 Nov 18.
2006
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| 94 | RUNX2
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| Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.
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| Javed A, Barnes GL, Pratap J, Antkowiak T, Gerstenfeld LC, van Wijnen AJ, Stein JL, Lian JB, Stein GS.
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| Proc Natl Acad Sci U S A 102(5):1454-9. Epub 2005 Jan 21. 2005
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| 95 | TWIST1, FGFR2, ACS3, RUNX2
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| A role for fibroblast growth factor receptor-2 in the altered osteoblast phenotype induced by Twist haploinsufficiency in the Saethre-Chotzen syndrome.
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| Guenou H, Kaabeche K, Mee SL, Marie PJ.
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| Hum Mol Genet 14(11):1429-39. Epub 2005 Apr 13. 2005
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| 96 | CCD, RUNX2
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| Dysregulation of chondrogenesis in human cleidocranial dysplasia.
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| Zheng Q, Sebald E, Zhou G, Chen Y, Wilcox W, Lee B, Krakow D.
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| Am J Hum Genet 77(2):305-12. Epub 2005 Jun 10. 2005
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| 97 | CCD, HPE3, SHH, RUNX2
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| Holoprosencephaly and cleidocranial dysplasia in a patient due to two position-effect mutations: case report and review of the literature.
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| Fernandez BA, Siegel-Bartelt J, Herbrick JA, Teshima I, Scherer SW.
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| Clin Genet 68(4):349-59. 2005
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| 98 | IBSP, RUNX2
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| Cooperative interactions between RUNX2 and homeodomain protein-binding sites are critical for the osteoblast-specific expression of the bone sialoprotein gene.
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| Roca H, Phimphilai M, Gopalakrishnan R, Xiao G, Franceschi RT.
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| J Biol Chem 280(35):30845-55. Epub 2005 Jul 5. 2005
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| 99 | CCD, RUNX2
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| Functional analysis of a novel RUNX2 missense mutation found in a family with cleidocranial dysplasia.
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| Puppin C, Pellizzari L, Fabbro D, Fogolari F, Tell G, Tessa A, Santorelli FM, Damante G.
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| J Hum Genet 50(12):679-83. Epub 2005 Oct 22. 2005
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| 100 | CBFB, MYH11, RUNX2
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| Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia.
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| Castilla LH, Perrat P, Martinez NJ, Landrette SF, Keys R, Oikemus S, Flanegan J, Heilman S, Garrett L, Dutra A, Anderson S, Pihan GA, Wolff L, Liu PP.
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| Proc Natl Acad Sci U S A 101(14):4924-9. Epub 2004 Mar 24. 2004
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| 101 | HDAC4, RUNX2
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| HDAC4: a corepressor controlling bone development.
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| Hug BA.
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| Cell 119(4):448-9. 2004
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| 102 | HDAC4, RUNX2
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| Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis.
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| Vega RB, Matsuda K, Oh J, Barbosa AC, Yang X, Meadows E, McAnally J, Pomajzl C, Shelton JM, Richardson JA, Karsenty G, Olson EN.
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| Cell 119(4):555-66. 2004
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| 103 | RUNX2
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| Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway.
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| Qiao M, Shapiro P, Kumar R, Passaniti A.
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| J Biol Chem 279(41):42709-18. Epub 2004 Aug 09. 2004
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| 104 | SMURF1, RUNX2
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| Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo.
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| Zhao M, Qiao M, Harris SE, Oyajobi BO, Mundy GR, Chen D.
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| J Biol Chem 279(13):12854-9. Epub 2003 Dec 29. 2004
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| 105 | RUNX2, SOST
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| Cbfa1/RUNX2 directs specific expression of the sclerosteosis gene (SOST).
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| Sevetson B, Taylor S, Pan Y.
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| J Biol Chem 279(14):13849-58. Epub 2004 Jan 22. 2004
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| 106 | ALX1, GATA1, MSX2, RUNX2
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| Identification of genes responsible for osteoblast differentiation from human mesodermal progenitor cells.
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| Qi H, Aguiar DJ, Williams SM, La Pean A, Pan W, Verfaillie CM.
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| Proc Natl Acad Sci U S A 100(6):3305-10. 2003
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| 107 | RUNX2, SP7
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| Transcriptional mechanisms in osteoblast differentiation and bone formation.
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| Nakashima K, de Crombrugghe B.
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| Trends Genet 19(8):458-66. 2003
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| 108 | LGALS3, RUNX1, RUNX2, RUNX3
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| Expression of galectin-3 in skeletal tissues is controlled by Runx2.
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| Stock M, Schafer H, Stricker S, Gross G, Mundlos S, Otto F.
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| J Biol Chem 278(19):17360-7. Epub 2003 Feb 25. 2003
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| 109 | CCD, RUNX2
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| Functional analysis of RUNX2 mutations in cleidocranial dysplasia: novel insights into genotype-phenotype correlations.
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| Yoshida T, Kanegane H, Osato M, Yanagida M, Miyawaki T, Ito Y, Shigesada K.
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| Blood Cells Mol Dis 30(2):184-93. 2003
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| 110 | PPARG, RUNX2
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| Activation of peroxisome proliferator-activated receptor-gamma inhibits the Runx2-mediated transcription of osteocalcin in osteoblasts.
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| Jeon MJ, Kim JA, Kwon SH, Kim SW, Park KS, Park SW, Kim SY, Shin CS.
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| J Biol Chem 278(26):23270-7. Epub 2003 Apr 18. 2003
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| 111 | RUNX2, BMP7
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| Transcriptional regulation of the human Runx2/Cbfa1 gene promoter by bone morphogenetic protein-7.
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| Tou L, Quibria N, Alexander JM.
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| Mol Cell Endocrinol 205(1-2):121-9. 2003
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| 112 | CCD, RUNX2
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| Mutations in the RUNX2 gene in patients with cleidocranial dysplasia.
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| Otto F, Kanegane H, Mundlos S.
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| Hum Mutat 19(3):209-16. Review. 2002
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| 113 | RUNX2, CCD
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| New mutations in the CBFA1 gene in two Mexican patients with cleidocranial dysplasia.
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| Machuca-Tzili L, Monroy-Jaramillo N, Gonzalez-Del Angel A, Kofman-Alfaro S.
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| Clin Genet 61(5):349-53. 2002
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| 114 | RUNX2
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| Functional analysis of RUNX2 mutations in Japanese patients with cleidocranial dysplasia demonstrates novel genotype-phenotype correlations.
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| Yoshida T, Kanegane H, Osato M, Yanagida M, Miyawaki T, Ito Y, Shigesada K.
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| Am J Hum Genet 71(4):724-38. 2002
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| 115 | CBFB, RUNX2
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| Cbfbeta interacts with Runx2 and has a critical role in bone development.
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| Kundu M, Javed A, Jeon JP, Horner A, Shum L, Eckhaus M, Muenke M, Lian JB, Yang Y, Nuckolls GH, Stein GS, Liu PP.
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| Nat Genet 32(4):639-44. 2002
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| 116 | CBFB, RUNX2
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| The core-binding factor beta subunit is required for bone formation and hematopoietic maturation.
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| Miller J, Horner A, Stacy T, Lowrey C, Lian JB, Stein G, Nuckolls GH, Speck NA.
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| Nat Genet 32(4):645-9. 2002
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| 117 | RUNX2
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| Alleles of RUNX2/CBFA1 gene are associated with differences in bone mineral density and risk of fracture.
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| Vaughan T, Pasco JA, Kotowicz MA, Nicholson GC, Morrison NA.
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| J Bone Miner Res 17(8):1527-34. 2002
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| 118 | RUNX2
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| Runx2, a multifunctional transcription factor in skeletal development.
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| Komori T.
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| J Cell Biochem 87(1):1-8. Review. 2002
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| 119 | DMP1, RUNX2
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| Dentin matrix protein 1, a target molecule for Cbfa1 in bone, is a unique bone marker gene.
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| Fen JQ, Zhang J, Dallas SL, Lu Y, Chen S, Tan X, Owen M, Harris SE, MacDougall M.
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| J Bone Miner Res 17(10):1822-31. 2002
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| 120 | FGFR2, RUNX2
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| Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2.
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| Xiao G, Jiang D, Gopalakrishnan R, Franceschi RT.
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| J Biol Chem 277(39):36181-7. Epub 2002 Aug 28. 2002
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| 121 | RUNX2
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| Characterization of an osteoblast-specific enhancer element in the CBFA1 gene.
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| Zambotti A, Makhluf H, Shen J, Ducy P.
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| J Biol Chem 277(44):41497-506. Epub 2002 Aug 16. 2002
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| 122 | CCD, RUNX2
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| Cleidocranial dysplasia with decreased bone density and biochemical findings of hypophosphatasia.
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| Morava E, Karteszi J, Weisenbach J, Caliebe A, Mundlos S, Mehes K.
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| Eur J Pediatr 161(11):619-22. Epub 2002 Oct 09. 2002
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| 123 | SMAD3, RUNX2, TGFB1
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| TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation.
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| Alliston T, Choy L, Ducy P, Karsenty G, Derynck R.
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| EMBO J 20(9):2254-72. 2001
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| 124 | RUNX2
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| Runx2: a novel oncogenic effector revealed by in vivo complementation and retroviral tagging.
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| Blyth K, Terry A, Mackay N, Vaillant F, Bell M, Cameron ER, Neil JC, Stewart M.
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| Oncogene 20(3):295-302. 2001
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| 125 | RUNX2
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| Analysis of type-I and type-II RUNX2 protein expression in osteoblasts.
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| Sudhakar S, Katz MS, Elango N.
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| Biochem Biophys Res Commun 286(1):74-9. 2001
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| 126 | RUNX2, TGFB1, TNFRSF11B
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| Stimulation of osteoprotegerin (OPG) gene expression by transforming growth factor-beta (TGF-beta). Mapping of the OPG promoter region that mediates TGF-beta effects.
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| Thirunavukkarasu K, Miles RR, Halladay DL, Yang X, Galvin RJ, Chandrasekhar S, Martin TJ, Onyia JE.
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| J Biol Chem 276(39):36241-50. 2001
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| 127 | CBFB, RUNX2
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| Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta.
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| Warren AJ, Bravo J, Williams RL, Rabbitts TH.
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| EMBO J 19(12):3004-15. 2000
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| 128 | CCD, RUNX2
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| PEBP2alphaA/CBFA1 mutations in Japanese cleidocranial dysplasia patients.
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| Zhang YW, Yasui N, Kakazu N, Abe T, Takada K, Imai S, Sato M, Nomura S, Ochi T, Okuzumi S, Nogami H, Nagai T, Ohashi H, Ito Y.
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| Gene 244(1-2):21-8. 2000
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| 129 | RUNX2
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| A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia.
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| Zhang YW, Yasui N, Ito K, Huang G, Fujii M, Hanai J, Nogami H, Ochi T, Miyazono K, Ito Y.
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| Proc Natl Acad Sci U S A 97(19):10549-54. 2000
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| 130 | RUNX2
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| Cbfa1 is a positive regulatory factor in chondrocyte maturation.
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| Enomoto H, Enomoto-Iwamoto M, Iwamoto M, Nomura S, Himeno M, Kitamura Y, Kishimoto T, Komori T.
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| 131 | CCD, RUNX2
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| A novel missense mutation of the CBFA1 gene in a family with cleidocranial dysplasia (CCD) and variable expressivity.
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| Golan I, Preising M, Wagener H, Baumert U, Niederdellmann H, Lorenz B, Mussig D.
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| 132 | CCD, RUNX2
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| 133 | RUNX2, CCD
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| Hum Mol Genet 8(12):2311-2316 1999
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| 134 | RUNX1, RUNX2, RUNX3
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| Runt domains take the lead in hematopoiesis and osteogenesis.
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| Werner MH, Shigesada K, Ito Y.
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| Nat Med 5(12):1356-7. No abstract available 1999
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| 135 | RUNX2
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| Genomic organization, expression of the human CBFA1 gene, and evidence for an alternative splicing event affecting protein function.
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| Mamm Genome 9 : 54-57. 1998
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| 136 | RUNX2
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| Genomic structure and isoform expression of the mouse, rat and human Cbfa1/Osf2 transcription factor.
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| Gene 214 : 187-197. 1998
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| 137 | RUNX2, ETS1, SPP1
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| Transcriptional regulation of osteopontin gene in vivo by PEBP2alphaA/CBFA1 and ETS1 in the skeletal tissues.
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| Oncogene 17 : 1517-1525. 1998
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| 138 | RUNX2, CCD
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| Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development.
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| Cell 89(5):765-71. 1997
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| 139 | RUNX2
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| Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts.
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| Komori T, Yagi H, Nomura S, Yamaguchi A, Sasaki K, Deguchi K, Shimizu Y, Bronson RT, Gao YH, Inada M, Sato M, Okamoto R, Kitamura Y, Yoshiki S, Kishimoto T.
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| Cell 89(5):755-64. 1997
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| 140 | RUNX2, CCD
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| Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia.
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| Mundlos S, Otto F, Mundlos C, Mulliken JB, Aylsworth AS, Albright S, Lindhout D, Cole WG, Henn W, Knoll JH, Owen MJ, Mertelsmann R, Zabel BU, Olsen BR.
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| Cell 89(5):773-9. 1997
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| 141 | RUNX2, CCD
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| Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation.
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| Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G.
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| Cell 89(5):747-54. 1997
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| 142 | RUNX2, CCD
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| Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia.
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| Nat Genet 16(3):307-10. 1997
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| 143 | RUNX2
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| The cDNA cloning of the transcripts of human PEBP2alphaA/CBFA1 mapped to 6p12.3-p21.1, the locus for cleidocranial dysplasia.
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| Zhang YW, Bae SC, Takahashi E, Ito Y.
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| Oncogene 15(3):367-71. 1997
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| 144 | RUNX2
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| Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex.
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| Banerjee C, McCabe LR, Choi JY, Hiebert SW, Stein JL, Stein GS, Lian JB.
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| J Cell Biochem 66(1):1-8. 1997
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| 145 | CCD,RUNX2
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| 146 | AML1, AMLT2, AMLT3, RUNX2, RUNX1, RUNX3
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