| 1 | RRAS, RRAS2
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| ERK1/2-induced phosphorylation of R-Ras GTPases stimulates their oncogenic potential.
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| Frémin C, Guégan JP, Plutoni C, Mahaffey J, Philips MR, Emery G, Meloche S.
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| Oncogene 35(43):5692-5698. doi: 10.1038/onc.2016.122. Epub 2016 Apr 18.
2016
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| 2 | CCDC88A, CDH5, RRAS
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| Girdin/GIV regulates transendothelial permeability by controlling VE-cadherin trafficking through the small GTPase, R-Ras.
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| Ichimiya H, Maeda K, Enomoto A, Weng L, Takahashi M, Murohara T.
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| Biochem Biophys Res Commun 461(2):260-7. doi: 10.1016/j.bbrc.2015.04.012. Epub 2015 Apr 11.
2015
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| 3 | ARF6, CYTH2, RALBP1, RRAS
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| RLIP76 regulates Arf6-dependent cell spreading and migration by linking ARNO with activated R-Ras at recycling endosomes.
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| Wurtzel JG, Lee S, Singhal SS, Awasthi S, Ginsberg MH, Goldfinger LE.
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| Biochem Biophys Res Commun 467(4):785-91. doi: 10.1016/j.bbrc.2015.10.064. Epub 2015 Oct 20.
2015
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| 4 | MRAS, RRAS, RRAS2
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| R-RAS2 overexpression in tumors of the human central nervous system.
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| Gutierrez-Erlandsson S, Herrero-Vidal P, Fernandez-Alfara M, Hernandez-Garcia S, Gonzalo-Flores S, Mudarra-Rubio A, Fresno M, Cubelos B.
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| Mol Cancer 12(1):127. doi: 10.1186/1476-4598-12-127.
2013
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| 5 | RAB5A, RAC1, RIN2, RRAS
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| A tale of three GTPases and a RIN in endothelial cell adhesion.
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| Fernandez-Borja M.
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| Cell Res 22(10):1426-8. doi: 10.1038/cr.2012.118. Epub 2012 Aug 14.
2012
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| 6 | RAB5A, RIN2, RRAS
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| The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling.
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| Sandri C, Caccavari F, Valdembri D, Camillo C, Veltel S, Santambrogio M, Lanzetti L, Bussolino F, Ivaska J, Serini G.
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| Cell Res 22(10):1479-501. doi: 10.1038/cr.2012.110. Epub 2012 Jul 24.
2012
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| 7 | RRAS
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| R-Ras is required for murine dendritic cell maturation and CD4+ T-cell priming.
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| Singh G, Hashimoto D, Yan X, Helft J, Park PJ, Ma G, Qiao RF, Kennedy CR, Chen SH, Merad M, Chan AM.
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| Blood 119(7):1693-701. doi: 10.1182/blood-2011-05-357319. Epub 2011 Dec 14.
2012
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| 8 | AFDN, RRAS
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| R-Ras controls axon branching through afadin in cortical neurons.
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| Iwasawa N, Negishi M, Oinuma I.
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| Mol Biol Cell 23(14):2793-804. doi: 10.1091/mbc.E12-02-0103. Epub 2012 May 16. 2012
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| 9 | FLNA, RRAS
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| R-Ras interacts with filamin a to maintain endothelial barrier function.
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| Griffiths GS, Grundl M, Allen JS 3rd, Matter ML.
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| J Cell Physiol 226(9):2287-96. doi: 10.1002/jcp.22565.
2011
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| 10 | RAC1, RRAS
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| R-Ras and Rac GTPase cross-talk regulates hematopoietic progenitor cell migration, homing, and mobilization.
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| Shang X, Cancelas JA, Li L, Guo F, Liu W, Johnson JF, Ficker A, Daria D, Geiger H, Ratner N, Zheng Y.
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| J Biol Chem 286(27):24068-78. doi: 10.1074/jbc.M111.226951. Epub 2011 May 13.
2011
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| 11 | RRAS
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| RRAS: A key regulator and an important prognostic biomarker in biliary atresia.
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| Zhao R, Li H, Shen C, Zheng S.
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| World J Gastroenterol 17(6):796-803. doi: 10.3748/wjg.v17.i6.796.
2011
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| 12 | FAM38A, PIEOZ1, RRAS
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| Integrin activation by Fam38A uses a novel mechanism of R-Ras targeting to the endoplasmic reticulum.
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| McHugh BJ, Buttery R, Lad Y, Banks S, Haslett C, Sethi T.
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| J Cell Sci 123(Pt 1):51-61. 2010
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| 13 | FLNA, RRAS
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| R-Ras regulates migration through an interaction with filamin A in melanoma cells.
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| Gawecka JE, Griffiths GS, Ek-Rylander B, Ramos JW, Matter ML.
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| PLoS One 5(6):e11269. doi: 10.1371/journal.pone.0011269.
2010
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| 14 | RRAS, ZDHHC19
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| Palmitoylation of R-Ras by human DHHC19, a palmitoyl transferase with a CaaX box.
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| Baumgart F, Corral-Escariz M, Pérez-Gil J, Rodríguez-Crespo I.
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| Biochim Biophys Acta. Mar;1798(3):592-604. doi: 10.1016/j.bbamem.2010.01.002. Epub 2010 Jan 13 2010
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| 15 | RRAS
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| Promoter cloning and characterization of the anti-vascular proliferation gene, R-ras: role of Ets- and Sp-binding motifs.
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| Xu L, Komatsu M.
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| J Biol Chem 284(5):2706-18. Epub 2008 Nov 14.
2009
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| 16 | RRAS, ZEB1
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| Transcription factor 8 activates R-Ras to regulate angiogenesis.
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| Inuzuka T, Tsuda M, Kawaguchi H, Ohba Y.
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| Biochem Biophys Res Commun 379(2):510-3. Epub 2008 Dec 29. 2009
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| 17 | MRAS, RRAS
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| M-Ras evolved independently of R-Ras and its neural function is conserved between mammalian and ascidian, which lacks classical Ras.
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| Keduka E, Kaiho A, Hamada M, Watanabe-Takano H, Takano K, Ogasawara M, Satou Y, Satoh N, Endo T.
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| Gene 429(1-2):49-58. doi: 10.1016/j.gene.2008.10.001. Epub 2008 Oct 11.
2009
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| 18 | RRAS
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| R-Ras controls axon specification upstream of glycogen synthase kinase-3beta through integrin-linked kinase.
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| Oinuma I, Katoh H, Negishi M.
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| J Biol Chem 282(1):303-18. Epub 2006 Nov 15.
2007
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| 19 | RRAS
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| R-Ras is a global regulator of vascular regeneration that suppresses intimal hyperplasia and tumor angiogenesis.
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| Komatsu M, Ruoslahti E.
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| Nat Med 11(12):1346-1350. Epub 2005 Nov 13. 2005
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| 20 | RRAS
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| R-Ras controls membrane protrusion and cell migration through the spatial regulation of Rac and Rho.
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| Wozniak MA, Kwong L, Chodniewicz D, Klemke RL, Keely PJ.
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| Mol Biol Cell 16(1):84-96. Epub 2004 Nov 3.
2005
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| 21 | RRAS
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| The C-terminal end of R-Ras contains a focal adhesion targeting signal.
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| Furuhjelm J, Peränen J.
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| J Cell Sci 116(Pt 18):3729-38. Epub 2003 Jul 30.
2003
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| 22 | RRAS
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| R-Ras promotes tumor growth of cervical epithelial cells.
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| Rincón-Arano H, Rosales R, Mora N, Rodriguez-Castañeda A, Rosales C.
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| Cancer 97(3):575-85.
2003
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| 23 | RRAS
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| R-Ras promotes focal adhesion formation through focal adhesion kinase and p130(Cas) by a novel mechanism that differs from integrins.
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| Kwong L, Wozniak MA, Collins AS, Wilson SD, Keely PJ.
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| Mol Cell Biol 23(3):933-49.
2003
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| 24 | EPHB2, RRAS
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| An Eph receptor regulates integrin activity through R-Ras.
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| Zou JX, Wang B, Kalo MS, Zisch AH, Pasquale EB, Ruoslahti E.
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| Proc Natl Acad Sci U S A 96(24):13813-8 1999
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| 25 | CYP2B, CYP2B6, CYP2B7P1, CYP2F1, EPOR, HERVK10T, JAK3, RRAS, ZNF134, ZNF14, ZNF44, ZNF91, ZNF97
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| Positioning of 72 potentially full size LTRs of human endogenous retroviruses HERV-K on the human chromosome 19 map. Occurrences of the LTRs in human gene sites.
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| Vinogradova T, Volik S, Lebedev Y, Shevchenko Y, Lavrentyeva I, Khil P, Grzeschik KH, Ashworth LK, Sverdlov E.
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| Gene 199(1-2):255-64. 1997
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| 26 | DBP, FPR1, IL11, MZF1, NGFG, RTN2, RRAS, SULT2A1, SYT3, TGFB1, ZFP40
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| Detailed comparative map of human chromosome 19q and related regions of the mouse genome.
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| Stubbs L, et al.
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| Genomics 35 : 499-508. 1996
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| 27 | RRAS
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| Structure of the human murine R-ras genes, novel genes closely related to ras proto-oncogenes.
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| Lowe DG, et al.
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| Cell 48 : 137-146. 1987
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