1 | MTOR, RRAGA, RRAGB, RRAGC, WDR35
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| RagA, an mTORC1 activator, interacts with a hedgehog signaling protein, WDR35/IFT121.
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| Sekiguchi T, Furuno N, Ishii T, Hirose E, Sekiguchi F, Wang Y, Kobayashi H.
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| Genes Cells. Feb;24(2):151-161. doi: 10.1111/gtc.12663. Epub 2019 Jan 15. 2019
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2 | MTOR, RRAGA
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| Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival.
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| Efeyan A, Zoncu R, Chang S, Gumper I, Snitkin H, Wolfson RL, Kirak O, Sabatini DD, Sabatini DM.
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| Nature Jan 31;493(7434):679-83. doi: 10.1038/nature11745. Epub 2012 Dec 23 2013
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3 | RRAGA, RRAGB, RRAGC, RRAGD, SH3BP4
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| dRAGging amino acid-mTORC1 signaling by SH3BP4.
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| Kim YM, Kim DH.
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| Mol Cells 35(1):1-6. doi: 10.1007/s10059-013-2249-1. Epub 2012 Dec 26. Review. 2013
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4 | LAMTOR1, LAMTOR3, RRAGA, RRAGC
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| Crystal structure of the Gtr1p-Gtr2p complex reveals new insights into the amino acid-induced TORC1 activation.
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| Gong R, Li L, Liu Y, Wang P, Yang H, Wang L, Cheng J, Guan KL, Xu Y.
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| Genes Dev 25(16):1668-73. Epub 2011 Aug 4.
2011
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5 | LAMTOR1, LAMTOR2, LAMTOR3, MTOR, RRAGA, RRAGB, RRAGC, RRAGD
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| Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.
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| Sancak Y, Bar-Peled L, Zoncu R, Markhard AL, Nada S, Sabatini DM.
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| Cell 141(2):290-303. Epub 2010 Apr 8. 2010
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6 | RRAGA, RRAGB, RRAGC, RRAGD
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| The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.
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| Sancak Y, Peterson TR, Shaul YD, Lindquist RA, Thoreen CC, Bar-Peled L, Sabatini DM.
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| Science 320(5882):1496-501. Epub 2008 May 22.
2008
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7 | RRAGA, RRAGC, RRAGD
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| A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D.
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| Sekiguchi T, Todaka Y, Wang Y, Hirose E, Nakashima N, Nishimoto T.
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| J Biol Chem 279(9):8343-50. Epub 2003 Dec 4.
2004
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8 | RRAGA
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| Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B.
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| Sekiguchi T, Hirose E, Nakashima N, Ii M, Nishimoto T.
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| J Biol Chem 276(10):7246-57. Epub 2000 Nov 9.
2001
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9 | RRAGA, RRAGB
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| RagA is a functional homologue of S. cerevisiae Gtr1p involved in the Ran/Gsp1-GTPase pathway.
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| Hirose E, Nakashima N, Sekiguchi T, Nishimoto T.
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| J Cell Sci 111 ( Pt 1):11-21.
1998
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10 | RRAGA
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| Interaction of an adenovirus 14.7-kilodalton protein inhibitor of tumor necrosis factor alpha cytolysis with a new member of the GTPase superfamily of signal transducers.
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| Li Y, Kang J, Horwitz MS.
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| J Virol 71(2):1576-82. 1997
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11 | RRAGA, RRAGB
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| Cloning of a novel family of mammalian GTP-binding proteins (RagA, RagBs, RagB1) with remote similarity to the Ras-related GTPases.
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| Schurmann A, Brauers A, Massmann S, Becker W, Joost HG.
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| J Biol Chem 270(48):28982-8. 1995
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