| 1 | CFTR, RNF5
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| Genetic Inhibition Of The Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated To F508del Cystic Fibrosis Mutation.
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| Tomati V, Sondo E, Armirotti A, Caci E, Pesce E, Marini M, Gianotti A, Jeon YJ, Cilli M, Pistorio A, Mastracci L, Ravazzolo R, Scholte B, Ronai Z, Galietta LJ, Pedemonte N.
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| Sci Rep 5:12138. doi: 10.1038/srep12138.
2015
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| 2 | ABCG5, ABCG8, RNF5, SYVN1
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| Inhibition of post-translational N-glycosylation by HRD1 that controls the fate of ABCG5/8 transporter.
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| Suzuki S, Shuto T, Sato T, Kaneko M, Takada T, Suico MA, Cyr DM, Suzuki H, Kai H.
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| Sci Rep 4:4258. doi: 10.1038/srep04258.
2014
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| 3 | CFTR, RNF185, RNF5
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| RNF185 is a novel E3 ligase of endoplasmic reticulum-associated degradation (ERAD) that targets cystic fibrosis transmembrane conductance regulator (CFTR).
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| El Khouri E, Le Pavec G, Toledano MB, Delaunay-Moisan A.
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| J Biol Chem 288(43):31177-91. doi: 10.1074/jbc.M113.470500. Epub 2013 Sep 9.
2013
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| 4 | JKAMP, RNF5
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| Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability.
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| Roy SJ, Glazkova I, Fréchette L, Iorio-Morin C, Binda C, Pétrin D, Trieu P, Robitaille M, Angers S, Hébert TE, Parent JL.
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| Mol Endocrinol 27(8):1245-66. doi: 10.1210/me.2013-1091. Epub 2013 Jun 24.
2013
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| 5 | ATG4B, RNF5
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| Regulation of ATG4B stability by RNF5 limits basal levels of autophagy and influences susceptibility to bacterial infection.
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| Kuang E, Okumura CY, Sheffy-Levin S, Varsano T, Shu VC, Qi J, Niesman IR, Yang HJ, López-Otín C, Yang WY, Reed JC, Broday L, Nizet V, Ronai ZA.
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| PLoS Genet 8(10):e1003007. doi: 10.1371/journal.pgen.1003007. Epub 2012 Oct 18.
2012
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| 6 | RNF5, SLC26A4
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| Roles of 17-AAG-induced molecular chaperones and Rma1 E3 ubiquitin ligase in folding and degradation of Pendrin.
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| Lee K, Hong TJ, Hahn JS.
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| FEBS Lett 586(16):2535-41. doi: 10.1016/j.febslet.2012.06.023. Epub 2012 Jun 27.
2012
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| 7 | CFTR, RNF5
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| The endoplasmic reticulum-associated Hsp40 DNAJB12 and Hsc70 cooperate to facilitate RMA1 E3-dependent degradation of nascent CFTRDeltaF508.
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| Grove DE, Fan CY, Ren HY, Cyr DM.
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| Mol Biol Cell 22(3):301-14. doi: 10.1091/mbc.E10-09-0760. Epub 2010 Dec 9.
2011
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| 8 | MAVS, RNF5
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| The E3 ubiquitin ligase RNF5 targets virus-induced signaling adaptor for ubiquitination and degradation.
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| Zhong B, Zhang Y, Tan B, Liu TT, Wang YY, Shu HB.
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| J Immunol 184(11):6249-55. doi: 10.4049/jimmunol.0903748. Epub 2010 May 5.
2010
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| 9 | JKAMP, RNF5
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| Regulation of endoplasmic reticulum-associated degradation by RNF5-dependent ubiquitination of JNK-associated membrane protein (JAMP).
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| Tcherpakov M, Delaunay A, Toth J, Kadoya T, Petroski MD, Ronai ZA.
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| J Biol Chem 284(18):12099-109. doi: 10.1074/jbc.M808222200. Epub 2009 Mar 6.
2009
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| 10 | RNF5, STING1
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| The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA.
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| Zhong B, Zhang L, Lei C, Li Y, Mao AP, Yang Y, Wang YY, Zhang XL, Shu HB.
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| Immunity 30(3):397-407. doi: 10.1016/j.immuni.2009.01.008. Epub 2009 Mar 12. 2009
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| 11 | AMFR, CFTR, RNF5
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| Gp78 cooperates with RMA1 in endoplasmic reticulum-associated degradation of CFTRDeltaF508.
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| Morito D, Hirao K, Oda Y, Hosokawa N, Tokunaga F, Cyr DM, Tanaka K, Iwai K, Nagata K.
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| Mol Biol Cell 19(4):1328-36. Epub 2008 Jan 23.PMID: 18216283 2008
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| 12 | RNF5
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| The ER-bound RING finger protein 5 (RNF5/RMA1) causes degenerative myopathy in transgenic mice and is deregulated in inclusion body myositis.
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| Delaunay A, Bromberg KD, Hayashi Y, Mirabella M, Burch D, Kirkwood B, Serra C, Malicdan MC, Mizisin AP, Morosetti R, Broccolini A, Guo LT, Jones SN, Lira SA, Puri PL, Shelton GD, Ronai Z.
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| PLoS One 3(2):e1609. doi: 10.1371/journal.pone.0001609.
2008
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| 13 | RNF5
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| Increased expression of the E3 ubiquitin ligase RNF5 is associated with decreased survival in breast cancer.
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| Bromberg KD, Kluger HM, Delaunay A, Abbas S, DiVito KA, Krajewski S, Ronai Z.
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| Cancer Res 67(17):8172-9. 2007
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| 14 | RNF5
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| G16-mediated activation of nuclear factor kappaB by the adenosine A1 receptor involves c-Src, protein kinase C, and ERK signaling.
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| Liu AM, Wong YH.
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| J Biol Chem 279(51):53196-204. Epub 2004 Oct 12. 2004
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| 15 | RNF5
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| NG2 immunoreactivity on human brain endothelial cells.
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| Pouly S, Prat A, Blain M, Olivier A, Antel J.
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| Acta Neuropathol (Berl) 102(4):313-20. 2001
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| 16 | RNF5
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| Cloning, expression and mapping of a novel RING-finger gene (RNF5), a human homologue of a putative zinc-finger gene from Caenorhabditis elegans.
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| Kyushiki H, Kuga Y, Suzuki M, Takahashi E, Horie M.
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| Cytogenet Cell Genet 79(1-2):114-7. 1997
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