Citations for
1CGAS, RNASEH2B
Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response.
Mackenzie KJ, Carroll P, Lettice L, Tarnauskaitė , Reddy K, Dix F, Revuelta A, Abbondati E, Rigby RE, Rabe B, Kilanowski F, Grimes G, Fluteau A, Devenney PS, Hill RE, Reijns MA, Jackson AP.
EMBO J 35(8):831-44. doi: 10.15252/embj.201593339. Epub 2016 Feb 22. 2016
2RNASEH2A, RNASEH2B, RNASEH2C
The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease.
Reijns MA, Bubeck D, Gibson LC, Graham SC, Baillie GS, Jones EY, Jackson AP.
J Biol Chem 286(12):10530-9. Epub 2010 Dec 22. 2011
3RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, TREX1
Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase.
Powell RD, Holland PJ, Hollis T, Perrino FW.
J Biol Chem 286(51):43596-600. doi: 10.1074/jbc.C111.317628. Epub 2011 Nov 7. 2011
4AGS2, AGS3, AGS4, RNASEH2A, RNASEH2B, RNASEH2C
The structure of the mammalian RNase H2 complex provides insight into RNA.NA hybrid processing to prevent immune dysfunction.
Shaban NM, Harvey S, Perrino FW, Hollis T.
J Biol Chem 285(6):3617-24. Epub 2009 Nov 18. 2010
5RNASEH2B, RNASEH2C
Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex.
Chon H, Vassilev A, DePamphilis ML, Zhao Y, Zhang J, Burgers PM, Crouch RJ, Cerritelli SM.
Nucleic Acids Res 37(1):96-110. Epub 2008 Nov 16. 2009
6RNASEH2A, RNASEH2B, RNASEH2C
Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex.
Chon H, Vassilev A, DePamphilis ML, Zhao Y, Zhang J, Burgers PM, Crouch RJ, Cerritelli SM.
Nucleic Acids Res 37(1):96-110. Epub 2008 Nov 16. 2009
7AGS1, AGS2, AGS3, AGS4, TREX1, RNASEH2A, RNASEH2B, RNASEH2C
Clinical and molecular phenotype of aicardi-goutieres syndrome.
Rice G, Patrick T, Parmar R, Taylor CF, Aeby A, Aicardi J, Artuch R, Montalto SA, Bacino CA, Barroso B, Baxter P, Benko WS, Bergmann C, Bertini E, Biancheri R, Blair EM, Blau N, Bonthron DT, Briggs T, Brueton LA, Brunner HG, Burke CJ, Carr IM, Carvalho DR, Chandler KE, Christen HJ, Corry PC, Cowan FM, Cox H, D'Arrigo S, Dean J, De Laet C, De Praeter C, Dery C, Ferrie CD, Flintoff K, Frints SG, Garcia-Cazorla A, Gener B, Goizet C, Goutieres F, Green AJ, Guet A, Hamel BC, Hayward BE, Heiberg A, Hennekam RC, Husson M, Jackson AP, Jayatunga R, Jiang YH, Kant SG, Kao A, King MD, Kingston HM, Klepper J, van der Knaap MS, Kornberg AJ, Kotzot D, Kratzer W, Lacombe D, Lagae L, Landrieu PG, Lanzi G, Leitch A, Lim MJ, Livingston JH, Lourenco CM, Lyall EG, Lynch SA, Lyons MJ, Marom D, McClure JP, McWilliam R, Melancon SB, Mewasingh LD, Moutard ML, Nischal KK, Ostergaard JR, Prendiville J, Rasmussen M, Rogers RC, Roland D, Rosser EM, Rostasy K, Roubertie A, Sanchis A, Schiffmann R, Scholl-Burgi S, Seal S, Shalev SA, Corcoles CS, Sinha GP, Soler D, Spiegel R, Stephenson JB, Tacke U, Tan TY, Till M, Tolmie JL, Tomlin P, Vagnarelli F, Valente EM, Van Coster RN, Van der Aa N, Vanderver A, Vles JS, Voit T, Wassmer E, Weschke B, Whiteford ML, Willemsen MA, Zankl A, Zuberi SM, Orcesi S, Fazzi E, Lebon P, Crow YJ.
Am J Hum Genet 81(4):713-25. Epub 2007 Sep 4. 2007
8AGS2, RNASEH2B, AGS3, RNASEH2A, RNASEH2C, AGS4
Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutieres syndrome and mimic congenital viral brain infection.
Crow YJ, Leitch A, Hayward BE, Garner A, Parmar R, Griffith E, Ali M, Semple C, Aicardi J, Babul-Hirji R, Baumann C, Baxter P, Bertini E, Chandler KE, Chitayat D, Cau D, Dery C, Fazzi E, Goizet C, King MD, Klepper J, Lacombe D, Lanzi G, Lyall H, Martinez-Frias ML, Mathieu M, McKeown C, Monier A, Oade Y, Quarrell OW, Rittey CD, Rogers RC, Sanchis A, Stephenson JB, Tacke U, Till M, Tolmie JL, Tomlin P, Voit T, Weschke B, Woods CG, Lebon P, Bonthron DT, Ponting CP, Jackson AP.
Nat Genet 38(8):910-6. Epub 2006 Jul 16. 2006
9C13orf1, DLEU7, RCBTB1, RNASEH2B, SETDB2
DLEU2 encodes an antisense RNA for the putative bicistronic RFP2/LEU5 gene in humans and mouse.
Corcoran MM, Hammarsund M, Zhu C, Lerner M, Kapanadze B, Wilson B, Larsson C, Forsberg L, Ibbotson RE, Einhorn S, Oscier DG, Grander D, Sangfelt O.
Genes Chromosomes Cancer 40(4):285-97. 2004