1 | BLM, RMI1, RMI2, TOP3A
|
| Mutations in TOP3A Cause a Bloom Syndrome-like Disorder.
|
| Martin CA, Sarlós K, Logan CV, Thakur RS, Parry DA, Bizard AH, Leitch A, Cleal L, Ali NS, Al-Owain MA, Allen W, Altmüller J, Aza-Carmona M, Barakat BAY, Barraza-García J, Begtrup A, Bogliolo M, Cho MT, Cruz-Rojo J, Dhahrabi HAM, Elcioglu NH; GOSgene, Gorman GS, Jobling R, Kesterton I, Kishita Y, Kohda M, Le Quesne Stabej P, Malallah AJ, Nürnberg P, Ohtake A, Okazaki Y, Pujol R, Ramirez MJ, Revah-Politi A, Shimura M, Stevens P, Taylor RW, Turner L, Williams H, Wilson C, Yigit G, Zahavich L, Alkuraya FS, Surralles J, Iglesais A, Murayama K, Wollnik B, Dattani M, Heath KE, Hickson ID, Jackson AP.
|
| Am J Hum Genet 103(2):221-231. doi: 10.1016/j.ajhg.2018.07.001. Epub 2018 Jul 26. Erratum in: Am J Hum Genet. 2018 Sep 6;103(3):456.
2018
|
2 | BLM, RMI1, RMI2, TOP3A
|
| Knockdown of RMI1 impairs DNA repair under DNA replication stress.
|
| Xu C, Fang L, Kong Y, Xiao C, Yang M, Du LQ, Liu Q.
|
| Biochem Biophys Res Commun 494(1-2):158-164. doi: 10.1016/j.bbrc.2017.10.062. Epub 2017 Oct 14.
2017
|
3 | RMI1, RMI2, TOP3A
|
| Accumulation and Phosphorylation of RecQ-Mediated Genome Instability Protein 1 (RMI1) at Serine 284 and Serine 292 during Mitosis.
|
| Xu C, Wang Y, Wang L, Wang Q, Du LQ, Fan S, Liu Q, Li L.
|
| Int J Mol Sci 16(11):26395-405. doi: 10.3390/ijms161125965.
2015
|
4 | BLM, RMI1, RMI2, TOP3A
|
| Multifaceted role of the Topo IIIα-RMI1-RMI2 complex and DNA2 in the BLM-dependent pathway of DNA break end resection.
|
| Daley JM, Chiba T, Xue X, Niu H, Sung P.
|
| Nucleic Acids Res 42(17):11083-91. doi: 10.1093/nar/gku803. Epub 2014 Sep 8.
2014
|
5 | BLM, DNA2, RMI1, RMI2, WRN
|
| DNA2 cooperates with the WRN and BLM RecQ helicases to mediate long-range DNA end resection in human cells.
|
| Sturzenegger A, Burdova K, Kanagaraj R, Levikova M, Pinto C, Cejka P, Janscak P.
|
| J Biol Chem 289(39):27314-26. doi: 10.1074/jbc.M114.578823. Epub 2014 Aug 13.
2014
|
6 | RMI1, TOP3A
|
| Structural and mechanistic insight into Holliday-junction dissolution by topoisomerase IIIα and RMI1.
|
| Bocquet N, Bizard AH, Abdulrahman W, Larsen NB, Faty M, Cavadini S, Bunker RD, Kowalczykowski SC, Cejka P, Hickson ID, Thomä NH.
|
| Nat Struct Mol Biol 21(3):261-8. doi: 10.1038/nsmb.2775. Epub 2014 Feb 9.
2014
|
7 | RMI1
|
| Genome instability and embryonic developmental defects in RMI1 deficient mice.
|
| Guiraldelli MF, Eyster C, Pezza RJ.
|
| DNA Repair (Amst) 12(10):835-43. doi: 10.1016/j.dnarep.2013.07.004. Epub 2013 Jul 27.
2013
|
8 | BLM, RMI1, RMI2, TOP3A
|
| Monopolar spindle 1 (MPS1) protein-dependent phosphorylation of RecQ-mediated genome instability protein 2 (RMI2) at serine 112 is essential for BLM-Topo III α-RMI1-RMI2 (BTR) protein complex function upon spindle assembly checkpoint (SAC) activation during mitosis.
|
| Pradhan A, Singh TR, Ali AM, Wahengbam K, Meetei AR.
|
| J Biol Chem 288(47):33500-8. doi: 10.1074/jbc.M113.470823. Epub 2013 Oct 9.
2013
|
9 | BLM, RMI1, RMI2, TOP3A
|
| RMI1 promotes DNA replication fork progression and recovery from replication fork stress.
|
| Yang J, O'Donnell L, Durocher D, Brown GW.
|
| Mol Cell Biol 32(15):3054-64. doi: 10.1128/MCB.00255-12. Epub 2012 May 29.
2012
|
10 | RMI1
|
| Glucose regulates RMI1 expression through the E2F pathways in adipose cells.
|
| Suwa A, Yoshino M, Kurama T, Shimokawa T, Aramori I.
|
| Endocrine 40(1):56-61. doi: 10.1007/s12020-011-9455-4. Epub 2011 Mar 24.
2011
|
11 | RMI1
|
| RMI1 attenuates tumor development and is essential for early embryonic survival.
|
| Chen H, You MJ, Jiang Y, Wang W, Li L.
|
| Mol Carcinog 50(2):80-8. doi: 10.1002/mc.20694. Epub 2010 Nov 23.
2011
|
12 | BLM, RMI1, TOP3A
|
| Human topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1.
|
| Yang J, Bachrati CZ, Ou J, Hickson ID, Brown GW.
|
| J Biol Chem 285(28):21426-36. doi: 10.1074/jbc.M110.123216. Epub 2010 May 5. 2010
|
13 | RMI1
|
| RMI1 deficiency in mice protects from diet and genetic-induced obesity.
|
| Suwa A, Yoshino M, Yamazaki C, Naitou M, Fujikawa R, Matsumoto S, Kurama T, Shimokawa T, Aramori I.
|
| FEBS J 277(3):677-86. doi: 10.1111/j.1742-4658.2009.07513.x. Epub 2009 Dec 29.
2010
|
14 | RMI1, RMI2
|
| Crystal structures of RMI1 and RMI2, two OB-fold regulatory subunits of the BLM complex.
|
| Wang F, Yang Y, Singh TR, Busygina V, Guo R, Wan K, Wang W, Sung P, Meetei AR, Lei M.
|
| Structure 18(9):1159-70. doi: 10.1016/j.str.2010.06.008. 2010
|
15 | BLM, RMI1, RMI2, TOP3A
|
| Developing T lymphocytes are uniquely sensitive to a lack of topoisomerase III alpha.
|
| Mönnich M, Hess I, Wiest W, Bachrati C, Hickson ID, Schorpp M, Boehm T.
|
| Eur J Immunol 40(9):2379-84. doi: 10.1002/eji.201040634.
2010
|
16 | BLM, RMI1, TOP3A
|
| Association between polymorphisms in RMI1, TOP3A, and BLM and risk of cancer, a case-control study.
|
| Broberg K, Huynh E, Schläwicke Engström K, Björk J, Albin M, Ingvar C, Olsson H, Höglund M.
|
| BMC Cancer 9:140. doi: 10.1186/1471-2407-9-140.
2009
|
17 | RMI1
|
| Functional role of BLAP75 in BLM-topoisomerase IIIalpha-dependent holliday junction processing.
|
| Raynard S, Zhao W, Bussen W, Lu L, Ding YY, Busygina V, Meetei AR, Sung P.
|
| J Biol Chem 283(23):15701-8. Epub 2008 Apr 4.
2008
|
18 | BLM, RMI1, RMI2, TOP3A
|
| RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability.
|
| Xu D, Guo R, Sobeck A, Bachrati CZ, Yang J, Enomoto T, Brown GW, Hoatlin ME, Hickson ID, Wang W.
|
| Genes Dev 22(20):2843-55.
2008
|
19 | BLM, RMI1, RMI2, TOP3A
|
| BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome.
|
| Singh TR, Ali AM, Busygina V, Raynard S, Fan Q, Du CH, Andreassen PR, Sung P, Meetei AR.
|
| Genes Dev 22(20):2856-68. 2008
|
20 | BLM, RMI1, TOP3A
|
| Holliday junction processing activity of the BLM-Topo IIIalpha-BLAP75 complex.
|
| Bussen W, Raynard S, Busygina V, Singh AK, Sung P.
|
| J Biol Chem 282(43):31484-92. Epub 2007 Aug 28.
2007
|
21 | RMI1, TOP3A, BLM
|
| A double Holliday junction dissolvasome comprising BLM, topoisomerase IIIalpha, and BLAP75.
|
| Raynard S, Bussen W, Sung P.
|
| J Biol Chem 281(20):13861-4. Epub 2006 Apr 4. 2006
|
22 | RMI1, TOP3A, BLM
|
| BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity.
|
| Yin J, Sobeck A, Xu C, Meetei AR, Hoatlin M, Li L, Wang W.
|
| EMBO J 24(7):1465-76. Epub 2005 Mar 17. 2005
|