1 | RLN1, RLN3, RXFP1, RXFP2
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| The different ligand-binding modes of relaxin family peptide receptors RXFP1 and RXFP2.
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| Scott DJ, Rosengren KJ, Bathgate RA.
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| Mol Endocrinol 26(11):1896-906. doi: 10.1210/me.2012-1188. Epub 2012 Sep 12.
2012
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2 | RLN1, RXFP1
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| Relaxin stimulates osteoclast differentiation and activation.
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| Ferlin A, Pepe A, Facciolli A, Gianesello L, Foresta C.
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| Bone 46(2):504-13. Epub 2009 Oct 13.PMID: 19833242 2010
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3 | RLN1, RXFP1
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| Relaxin signaling activates peroxisome proliferator-activated receptor gamma.
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| Singh S, Bennett RG.
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| Mol Cell Endocrinol 315(1-2):239-45. Epub 2009 Aug 25.PMID: 19712722 2010
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4 | RLN1
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| Relaxin stimulates interleukin-6 and interleukin-8 secretion from the extraplacental chorionic cytotrophoblast.
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| Bryant-Greenwood GD, Yamamoto SY, Sadowsky DW, Gravett MG, Novy MJ.
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| Placenta 30(7):599-606. Epub 2009 May 20.
2009
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5 | RLN1
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| Relaxin plays an important role in the regulation of airway structure and function.
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| Samuel CS, Royce SG, Burton MD, Zhao C, Tregear GW, Tang ML.
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| Endocrinology 148(9):4259-66. Epub 2007 Jun 21.
2007
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6 | RLN1
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| Relaxin signalling in THP-1 cells uses a novel phosphotyrosine-dependent pathway.
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| Anand-Ivell R, Heng K, Bartsch O, Ivell R.
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| Mol Cell Endocrinol 272(1-2):1-13. Epub 2007 Apr 6.
2007
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7 | RLN1
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| Relaxin promotes prostate cancer progression.
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| Feng S, Agoulnik IU, Bogatcheva NV, Kamat AA, Kwabi-Addo B, Li R, Ayala G, Ittmann MM, Agoulnik AI.
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| Clin Cancer Res 13(6):1695-702.
2007
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8 | RLN1, RLN2, RLN3
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| Regulation of the human relaxin genes H1 and H2 by steroid hormones.
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| Garibay-Tupas JL, Okazaki KJ, Tashima LS, Yamamoto S, Bryant-Greenwood GD.
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| Mol Cell Endocrinol 219(1-2):115-25. 2004
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9 | RLN1, RLN2, RXFP1
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| Increased expression of the relaxin receptor (LGR7) in human endometrium during the secretory phase of the menstrual cycle.
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| Bond CP, Parry LJ, Samuel CS, Gehring HM, Lederman FL, Rogers PA, Summers RJ.
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| J Clin Endocrinol Metab 89(7):3477-85. 2004
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10 | EDN1, RLN1
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| Relaxin, a pregnancy hormone, is a functional endothelin-1 antagonist: attenuation of endothelin-1-mediated vasoconstriction by stimulation of endothelin type-B receptor expression via ERK-1/2 and nuclear factor-kappaB.
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| Dschietzig T, Bartsch C, Richter C, Laule M, Baumann G, Stangl K.
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| Circ Res 92(1):32-40. 2003
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11 | RLN1, RLN2
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| Isolation and analysis of the 3'-untranslated regions of the human relaxin H1 and H2 genes.
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| Garibay-Tupas JL, Bao S, Kim MT, Tashima LS, Bryant-Greenwood GD.
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| J Mol Endocrinol 24(2):241-52. 2000
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12 | RLN1, RLN2
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| Two human relaxin genes are on chromosome 9.
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| Crawford RJ, et al.
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| EMBO J 3 : 2341-2345. 1984
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