Citations for
1BCR, EZR, RICTOR
Rictor positively regulates B cell receptor signaling by modulating actin reorganization via ezrin.
Huang L, Zhang Y, Xu C, Gu X, Niu L, Wang J, Sun X, Bai X, Xuan X, Li Q, Shi C, Yu B, Miller H, Yang G, Westerberg LS, Liu W, Song W, Zhao X, Liu C.
PLoS Biol 15(8):e2001750. doi: 10.1371/journal.pbio.2001750. eCollection 2017 Aug. 2017
2MAPKAP1, MTOR, NBN, RICTOR
Interaction between NBS1 and the mTOR/Rictor/SIN1 complex through specific domains.
Wang JQ, Chen JH, Chen YC, Chen MY, Hsieh CY, Teng SC, Wu KJ.
PLoS One 8(6):e65586. doi: 10.1371/journal.pone.0065586. Print 2013. 2013
3CHUK, IKBKB, RICTOR
IKK interacts with rictor and regulates mTORC2.
Xu Y, Lai E, Liu J, Lin J, Yang C, Jia C, Li Y, Bai X, Li M.
Cell Signal 25(11):2239-45. doi: 10.1016/j.cellsig.2013.07.008. Epub 2013 Jul 17. 2013
4RICTOR
From PTEN loss of expression to RICTOR role in smooth muscle differentiation: complex involvement of the mTOR pathway in leiomyosarcomas and pleomorphic sarcomas.
Gibault L, Ferreira C, Pérot G, Audebourg A, Chibon F, Bonnin S, Lagarde P, Vacher-Lavenu MC, Terrier P, Coindre JM, Aurias A.
Mod Pathol 25(2):197-211. doi: 10.1038/modpathol.2011.163. Epub 2011 Nov 11. 2012
5RICTOR
A critical role for rictor in T lymphopoiesis.
Tang F, Wu Q, Ikenoue T, Guan KL, Liu Y, Zheng P.
J Immunol 189(4):1850-7. Epub 2012 Jul 18. 2012
6RICTOR
Rictor regulates cell migration by suppressing RhoGDI2.
Agarwal NK, Chen CH, Cho H, Boulbès DR, Spooner E, Sarbassov DD.
Oncogene ncogene. 2012 Jul 9. doi: 10.1038/onc.2012.287. [Epub ahead of print] 2012
7RICTOR
Multiple site acetylation of Rictor stimulates mammalian target of rapamycin complex 2 (mTORC2)-dependent phosphorylation of Akt protein.
Glidden EJ, Gray LG, Vemuru S, Li D, Harris TE, Mayo MW.
J Biol Chem 287(1):581-8. Epub 2011 Nov 14. 2012
8FBXW7, RICTOR
Rictor regulates FBXW7-dependent c-Myc and cyclin E degradation in colorectal cancer cells.
Guo Z, Zhou Y, Evers BM, Wang Q.
Biochem Biophys Res Commun 418(2):426-32. doi: 10.1016/j.bbrc.2012.01.054. Epub 2012 Jan 20. 2012
9CRTC2, PINK1, RICTOR
A new cytosolic pathway from a Parkinson disease-associated kinase, BRPK/PINK1: activation of AKT via mTORC2.
Murata H, Sakaguchi M, Jin Y, Sakaguchi Y, Futami J, Yamada H, Kataoka K, Huh NH.
J Biol Chem 286(9):7182-9. Epub 2010 Dec 21. 2011
10CRTC2, RICTOR
Endoplasmic reticulum is a main localization site of mTORC2.
Boulbés DR, Shaiken T, Sarbassov dos D.
Biochem Biophys Res Commun 413(1):46-52. Epub 2011 Aug 16. 2011
11RICTOR
Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size.
Gu Y, Lindner J, Kumar A, Yuan W, Magnuson MA.
Diabetes 60(3):827-37. Epub 2011 Jan 24. 2011
12CRTC2, MTOR, RICTOR, RPL23A
mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide.
Oh WJ, Wu CC, Kim SJ, Facchinetti V, Julien LA, Finlan M, Roux PP, Su B, Jacinto E.
EMBO J 29(23):3939-51. Epub 2010 Nov 2. 2010
13RICTOR
mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis.
Zhang F, Zhang X, Li M, Chen P, Zhang B, Guo H, Cao W, Wei X, Cao X, Hao X, Zhang N.
Cancer Res 70(22):9360-70. Epub 2010 Oct 26. 2010
14RICTOR, SGK1
Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction.
Gao D, Wan L, Inuzuka H, Berg AH, Tseng A, Zhai B, Shaik S, Bennett E, Tron AE, Gasser JA, Lau A, Gygi SP, Harper JW, DeCaprio JA, Toker A, Wei W.
Mol Cell 39(5):797-808. 2010
15RICTOR, RPS6KB1
Rictor is a novel target of p70 S6 kinase-1.
Treins C, Warne PH, Magnuson MA, Pende M, Downward J.
Oncogene 29(7):1003-16. Epub 2009 Nov 23. 2010
16RICTOR, RPS6KB1
Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1.
Dibble CC, Asara JM, Manning BD.
Mol Cell Biol 29(21):5657-70. Epub 2009 Aug 31. 2009
17HSPA4, RICTOR
Hsp70 associates with Rictor and is required for mTORC2 formation and activity.
Martin J, Masri J, Bernath A, Nishimura RN, Gera J.
Biochem Biophys Res Commun 372(4):578-83. Epub 2008 May 27. 2008
18RICTOR, ILK
Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival.
McDonald PC, Oloumi A, Mills J, Dobreva I, Maidan M, Gray V, Wederell ED, Bally MB, Foster LJ, Dedhar S.
Cancer Res 68(6):1618-24. 2008
19HSPA4, RICTOR
Hsp70 associates with Rictor and is required for mTORC2 formation and activity.
Martin J, Masri J, Bernath A, Nishimura RN, Gera J.
Biochem Biophys Res Commun 372(4):578-83. Epub 2008 May 27. 2008
20PRR5, RICTOR
Identification of Protor as a novel Rictor-binding component of mTOR complex-2.
Pearce LR, Huang X, Boudeau J, Paw?owski R, Wullschleger S, Deak M, Ibrahim AF, Gourlay R, Magnuson MA, Alessi DR.
Biochem J 405(3):513-22. 2007
21CRTC2, RICTOR, MAPKAP1
Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity.
Yang Q, Inoki K, Ikenoue T, Guan KL.
Genes Dev 20(20):2820-32. 2006