Citations for
Molecular chaperoning function of Ric-8 is to fold nascent heterotrimeric G protein α subunits.
Chan P, Thomas CJ, Sprang SR, Tall GG.
Proc Natl Acad Sci U S A 110(10):3794-9. doi: 10.1073/pnas.1220943110. Epub 2013 Feb 19. 2013
Ric-8 regulation of heterotrimeric G proteins.
Tall GG.
J Recept Signal Transduct Res 33(3):139-43. doi: 10.3109/10799893.2013.763828. Epub 2013 Feb 6. Review. 2013
Ric-8 proteins are molecular chaperones that direct nascent G protein α subunit membrane association.
Gabay M, Pinter ME, Wright FA, Chan P, Murphy AJ, Valenzuela DM, Yancopoulos GD, Tall GG.
Sci Signal 4(200):ra79. doi: 10.1126/scisignal.2002223. 2011
The Ric-8B gene is highly expressed in proliferating preosteoblastic cells and downregulated during osteoblast differentiation in a SWI/SNF- and C/EBPbeta-mediated manner.
Grandy R, Sepulveda H, Aguilar R, Pihan P, Henriquez B, Olate J, Montecino M.
Mol Cell Biol 31(14):2997-3008. doi: 10.1128/MCB.05096-11. Epub 2011 May 23. 2011
Ric-8B is a GTP-dependent G protein alphas guanine nucleotide exchange factor.
Chan P, Gabay M, Wright FA, Tall GG.
J Biol Chem 286(22):19932-42. doi: 10.1074/jbc.M110.163675. Epub 2011 Apr 5. 2011
Ric-8B stabilizes the alpha subunit of stimulatory G protein by inhibiting its ubiquitination.
Nagai Y, Nishimura A, Tago K, Mizuno N, Itoh H.
J Biol Chem 285(15):11114-20. doi: 10.1074/jbc.M109.063313. Epub 2010 Feb 4. 2010
Ric-8B promotes functional expression of odorant receptors.
Von Dannecker LE, Mercadante AF, Malnic B.
Proc Natl Acad Sci U S A 103(24):9310-4. Epub 2006 Jun 5. 2006
Human brain synembryn interacts with Gsalpha and Gqalpha and is translocated to the plasma membrane in response to isoproterenol and carbachol.
Klattenhoff C, Montecino M, Soto X, Guzmán L, Romo X, García MA, Mellstrom B, Naranjo JR, Hinrichs MV, Olate J.
J Cell Physiol 195(2):151-7. 2003