1 | RIC8A, RIC8B
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| Molecular chaperoning function of Ric-8 is to fold nascent heterotrimeric G protein α subunits.
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| Chan P, Thomas CJ, Sprang SR, Tall GG.
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| Proc Natl Acad Sci U S A 110(10):3794-9. doi: 10.1073/pnas.1220943110. Epub 2013 Feb 19.
2013
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2 | RIC8A
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| Ablation of RIC8A function in mouse neurons leads to a severe neuromuscular phenotype and postnatal death.
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| Ruisu K, Kask K, Meier R, Saare M, Raid R, Veraksitš A, Karis A, Tõnissoo T, Pooga M.
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| PLoS One 8(8):e74031. doi: 10.1371/journal.pone.0074031. eCollection 2013.
2013
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3 | RIC8A
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| Ric-8A, a guanine nucleotide exchange factor for heterotrimeric G proteins, is critical for cranial neural crest cell migration.
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| Fuentealba J, Toro-Tapia G, Arriagada C, Riquelme L, Beyer A, Henriquez JP, Caprile T, Mayor R, Marcellini S, Hinrichs MV, Olate J, Torrejón M.
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| Dev Biol 378(2):74-82. doi: 10.1016/j.ydbio.2013.04.005. Epub 2013 Apr 12.
2013
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4 | RIC8A, RIC8B
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| Ric-8 regulation of heterotrimeric G proteins.
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| Tall GG.
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| J Recept Signal Transduct Res 33(3):139-43. doi: 10.3109/10799893.2013.763828. Epub 2013 Feb 6. Review.
2013
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5 | NCAM1, RIC8A
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| NCAM180 regulates Ric8A membrane localization and potentiates β-adrenergic response.
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| Amoureux MC, Nicolas S, Rougon G.
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| PLoS One 7(2):e32216. doi: 10.1371/journal.pone.0032216. Epub 2012 Feb 22.
2012
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6 | RGS14, RIC8A
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| Activation of the Regulator of G Protein Signaling 14-Gαi1-GDP Signaling Complex Is Regulated by Resistance to Inhibitors of Cholinesterase-8A.
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| Vellano CP, Shu FJ, Ramineni S, Yates CK, Tall GG, Hepler JR.
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| Biochemistry 50(5):752-62. Epub 2011 Jan 11.PMID: 21158412 2011
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7 | RIC8A, RIC8B
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| Ric-8 proteins are molecular chaperones that direct nascent G protein α subunit membrane association.
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| Gabay M, Pinter ME, Wright FA, Chan P, Murphy AJ, Valenzuela DM, Yancopoulos GD, Tall GG.
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| Sci Signal 4(200):ra79. doi: 10.1126/scisignal.2002223.
2011
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8 | RIC8A, RIC8B
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| Ric-8B is a GTP-dependent G protein alphas guanine nucleotide exchange factor.
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| Chan P, Gabay M, Wright FA, Tall GG.
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| J Biol Chem 286(22):19932-42. doi: 10.1074/jbc.M110.163675. Epub 2011 Apr 5.
2011
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9 | RIC8A
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| Ric-8A and Gi alpha recruit LGN, NuMA, and dynein to the cell cortex to help orient the mitotic spindle.
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| Woodard GE, Huang NN, Cho H, Miki T, Tall GG, Kehrl JH.
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| Mol Cell Biol 30(14):3519-30. Epub 2010 May 17.PMID: 20479129 2010
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10 | RIC8A
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| Ric-8A catalyzes guanine nucleotide exchange on G alphai1 bound to the GPR/GoLoco exchange inhibitor AGS3.
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| Thomas CJ, Tall GG, Adhikari A, Sprang SR.
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| J Biol Chem 283(34):23150-60. Epub 2008 Jun 9.PMID: 18541531 2008
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11 | ADCY5, RIC8A
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| Regulation of type V adenylate cyclase by Ric8a, a guanine nucleotide exchange factor.
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| Wang SC, Lai HL, Chiu YT, Ou R, Huang CL, Chern Y.
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| Biochem J 406(3):383-8.PMID: 17593019 2007
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12 | RIC8A
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| Ric-8 controls Drosophila neural progenitor asymmetric division by regulating heterotrimeric G proteins.
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| Wang H, Ng KH, Qian H, Siderovski DP, Chia W, Yu F.
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| Nat Cell Biol 7(11):1091-8.PMID: 16228012 2005
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13 | RIC8A
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| Drosophila Ric-8 is essential for plasma-membrane localization of heterotrimeric G proteins.
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| Hampoelz B, Hoeller O, Bowman SK, Dunican D, Knoblich JA.
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| Nat Cell Biol 7(11):1099-105.PMID: 16228011 2005
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14 | RIC8A
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| Human brain synembryn interacts with Gsalpha and Gqalpha and is translocated to the plasma membrane in response to isoproterenol and carbachol.
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| Klattenhoff C, Montecino M, Soto X, Guzman L, Romo X, De Los Angeles Garcia M, Mellstrom B, Naranjo JR, Hinrichs MV, Olate J.
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| J Cell Physiol 195(2):151-7. 2003
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15 | CHAMP1, CYP2E1, DIP2C, DOC2B, FOXD4, FRG1, GAS8, RIC8A, SDHA, TRIM7, ZMYND11
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| Telomere length and the expression of natural telomeric genes in human fibroblasts.
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| Ning Y, Xu JF, Li Y, Chavez L, Riethman HC, Lansdorp PM, Weng NP.
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| Hum Mol Genet 12(11):1329-36. 2003
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16 | RIC8A
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| Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor.
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| Tall GG, Krumins AM, Gilman AG.
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| J Biol Chem 278(10):8356-62. Epub 2002 Dec 30.PMID: 12509430 2003
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17 | RIC8A, RIC8B
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| Human brain synembryn interacts with Gsalpha and Gqalpha and is translocated to the plasma membrane in response to isoproterenol and carbachol.
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| Klattenhoff C, Montecino M, Soto X, Guzmán L, Romo X, García MA, Mellstrom B, Naranjo JR, Hinrichs MV, Olate J.
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| J Cell Physiol 195(2):151-7.
2003
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