Citations for
1RIC8A, RIC8B
Molecular chaperoning function of Ric-8 is to fold nascent heterotrimeric G protein α subunits.
Chan P, Thomas CJ, Sprang SR, Tall GG.
Proc Natl Acad Sci U S A 110(10):3794-9. doi: 10.1073/pnas.1220943110. Epub 2013 Feb 19. 2013
2RIC8A
Ablation of RIC8A function in mouse neurons leads to a severe neuromuscular phenotype and postnatal death.
Ruisu K, Kask K, Meier R, Saare M, Raid R, Veraksitš A, Karis A, Tõnissoo T, Pooga M.
PLoS One 8(8):e74031. doi: 10.1371/journal.pone.0074031. eCollection 2013. 2013
3RIC8A
Ric-8A, a guanine nucleotide exchange factor for heterotrimeric G proteins, is critical for cranial neural crest cell migration.
Fuentealba J, Toro-Tapia G, Arriagada C, Riquelme L, Beyer A, Henriquez JP, Caprile T, Mayor R, Marcellini S, Hinrichs MV, Olate J, Torrejón M.
Dev Biol 378(2):74-82. doi: 10.1016/j.ydbio.2013.04.005. Epub 2013 Apr 12. 2013
4RIC8A, RIC8B
Ric-8 regulation of heterotrimeric G proteins.
Tall GG.
J Recept Signal Transduct Res 33(3):139-43. doi: 10.3109/10799893.2013.763828. Epub 2013 Feb 6. Review. 2013
5NCAM1, RIC8A
NCAM180 regulates Ric8A membrane localization and potentiates β-adrenergic response.
Amoureux MC, Nicolas S, Rougon G.
PLoS One 7(2):e32216. doi: 10.1371/journal.pone.0032216. Epub 2012 Feb 22. 2012
6RGS14, RIC8A
Activation of the Regulator of G Protein Signaling 14-Gαi1-GDP Signaling Complex Is Regulated by Resistance to Inhibitors of Cholinesterase-8A.
Vellano CP, Shu FJ, Ramineni S, Yates CK, Tall GG, Hepler JR.
Biochemistry 50(5):752-62. Epub 2011 Jan 11.PMID: 21158412 2011
7RIC8A, RIC8B
Ric-8 proteins are molecular chaperones that direct nascent G protein α subunit membrane association.
Gabay M, Pinter ME, Wright FA, Chan P, Murphy AJ, Valenzuela DM, Yancopoulos GD, Tall GG.
Sci Signal 4(200):ra79. doi: 10.1126/scisignal.2002223. 2011
8RIC8A, RIC8B
Ric-8B is a GTP-dependent G protein alphas guanine nucleotide exchange factor.
Chan P, Gabay M, Wright FA, Tall GG.
J Biol Chem 286(22):19932-42. doi: 10.1074/jbc.M110.163675. Epub 2011 Apr 5. 2011
9RIC8A
Ric-8A and Gi alpha recruit LGN, NuMA, and dynein to the cell cortex to help orient the mitotic spindle.
Woodard GE, Huang NN, Cho H, Miki T, Tall GG, Kehrl JH.
Mol Cell Biol 30(14):3519-30. Epub 2010 May 17.PMID: 20479129 2010
10RIC8A
Ric-8A catalyzes guanine nucleotide exchange on G alphai1 bound to the GPR/GoLoco exchange inhibitor AGS3.
Thomas CJ, Tall GG, Adhikari A, Sprang SR.
J Biol Chem 283(34):23150-60. Epub 2008 Jun 9.PMID: 18541531 2008
11ADCY5, RIC8A
Regulation of type V adenylate cyclase by Ric8a, a guanine nucleotide exchange factor.
Wang SC, Lai HL, Chiu YT, Ou R, Huang CL, Chern Y.
Biochem J 406(3):383-8.PMID: 17593019 2007
12RIC8A
Ric-8 controls Drosophila neural progenitor asymmetric division by regulating heterotrimeric G proteins.
Wang H, Ng KH, Qian H, Siderovski DP, Chia W, Yu F.
Nat Cell Biol 7(11):1091-8.PMID: 16228012 2005
13RIC8A
Drosophila Ric-8 is essential for plasma-membrane localization of heterotrimeric G proteins.
Hampoelz B, Hoeller O, Bowman SK, Dunican D, Knoblich JA.
Nat Cell Biol 7(11):1099-105.PMID: 16228011 2005
14RIC8A
Human brain synembryn interacts with Gsalpha and Gqalpha and is translocated to the plasma membrane in response to isoproterenol and carbachol.
Klattenhoff C, Montecino M, Soto X, Guzman L, Romo X, De Los Angeles Garcia M, Mellstrom B, Naranjo JR, Hinrichs MV, Olate J.
J Cell Physiol 195(2):151-7. 2003
15CHAMP1, CYP2E1, DIP2C, DOC2B, FOXD4, FRG1, GAS8, RIC8A, SDHA, TRIM7, ZMYND11
Telomere length and the expression of natural telomeric genes in human fibroblasts.
Ning Y, Xu JF, Li Y, Chavez L, Riethman HC, Lansdorp PM, Weng NP.
Hum Mol Genet 12(11):1329-36. 2003
16RIC8A
Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor.
Tall GG, Krumins AM, Gilman AG.
J Biol Chem 278(10):8356-62. Epub 2002 Dec 30.PMID: 12509430 2003
17RIC8A, RIC8B
Human brain synembryn interacts with Gsalpha and Gqalpha and is translocated to the plasma membrane in response to isoproterenol and carbachol.
Klattenhoff C, Montecino M, Soto X, Guzmán L, Romo X, García MA, Mellstrom B, Naranjo JR, Hinrichs MV, Olate J.
J Cell Physiol 195(2):151-7. 2003