| 1 | RHOA, TET2
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| Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis.
|
| Zang S, Li J, Yang H, Zeng H, Han W, Zhang J, Lee M, Moczygemba M, Isgandarova S, Yang Y, Zhou Y, Rao A, You MJ, Sun D, Huang Y.
|
| J Clin Invest 127(8):2998-3012. doi: 10.1172/JCI92026. Epub 2017 Jul 10.
2017
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| 2 | PKHD1, RHOA, SMURF1, SMURF2
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| NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology
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| Kaimori JY, Lin CC, Outeda P, Garcia-Gonzalez MA, Menezes LF, Hartung EA, Li A, Wu G, Fujita H, Sato Y, Nakanuma Y, Yamamoto S, Ichimaru N, Takahara S, Isaka Y, Watnick T, Onuchic LF, Guay-Woodford LM, Germino GG
|
| Sci Rep. Aug 10;7(1):7733. doi: 10.1038/s41598-017-08284-4. 2017
|
| 3 | FMN1, RHOA
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| RhoA regulates actin network dynamics during apical surface emergence in multiciliated epithelial cells.
|
| Sedzinski J, Hannezo E, Tu F, Biro M, Wallingford JB.
|
| J Cell Sci. Jan 15;130(2):420-428. doi: 10.1242/jcs.194704. Erratum in: J Cell Sci. 2017 Mar 1;130(5):1017. 2017
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| 4 | ARHGEF40, KRT18, KRT8, RHOA
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| Interplay between Solo and keratin filaments is crucial for mechanical force-induced stress fiber reinforcement.
|
| Fujiwara S, Ohashi K, Mashiko T, Kondo H, Mizuno K.
|
| Mol Biol Cell 27(6):954-66. doi: 10.1091/mbc.E15-06-0417. Epub 2016 Jan 28.
2016
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| 5 | ARHGEF2, CGN, RHOA
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| Role of Cingulin in Agonist-induced Vascular Endothelial Permeability.
|
| Tian Y, Gawlak G, Tian X, Shah AS, Sarich N, Citi S, Birukova AA.
|
| J Biol Chem 291(45):23681-23692. Epub 2016 Sep 2.
2016
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| 6 | MYLPF, RHOA
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| RhoA-mediated MLC2 regulates actin dynamics for cytokinesis in meiosis.
|
| Duan X, Liu J, Zhu CC, Wang QC, Cui XS, Kim NH, Xiong B, Sun SC.
|
| Cell Cycle. 15(3):471-7. doi: 10.1080/15384101.2015.1128590. Epub 2015 Dec 23 2016
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| 7 | ADGRG1, GNA12, GNA13, RHOA
|
| The adhesion GPCR Gpr56 regulates oligodendrocyte development via interactions with Gα12/13 and RhoA.
|
| Ackerman SD, Garcia C, Piao X, Gutmann DH, Monk KR.
|
| Nat Commun 6:6122. doi: 10.1038/ncomms7122. 2015
|
| 8 | PTK2, PXN, RACGAP1, RHOA
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| RacGAP1-driven focal adhesion formation promotes melanoma transendothelial migration through mediating adherens junction disassembly.
|
| Zhang P, Bai H, Fu C, Chen F, Zeng P, Wu C, Ye Q, Dong C, Song Y, Song E.
|
| Biochem Biophys Res Commun 459(1):1-9. doi: 10.1016/j.bbrc.2014.11.088.
2015
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| 9 | DLC1, RHOA, TNS1
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| Tensin1 positively regulates RhoA activity through its interaction with DLC1.
|
| Shih YP, Sun P, Wang A, Lo SH.
|
| Biochim Biophys Acta 1853(12):3258-65. doi: 10.1016/j.bbamcr.2015.09.028. Epub 2015 Sep 28.
2015
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| 10 | ADD1, RHOA
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| Adducin is required for desmosomal cohesion in keratinocytes.
|
| Rötzer V, Breit A, Waschke J, Spindler V.
|
| J Biol Chem 289(21):14925-40. doi: 10.1074/jbc.M113.527127. Epub 2014 Apr 7.
2014
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| 11 | GEM, GEMIP, RHOA
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| Gem GTPase acts upstream Gmip/RhoA to regulate cortical actin remodeling and spindle positioning during early mitosis.
|
| Andrieu G, Quaranta M, Leprince C, Cuvillier O, Hatzoglou A.
|
| Carcinogenesis 35(11):2503-11. doi: 10.1093/carcin/bgu185. Epub 2014 Aug 30.
2014
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| 12 | CDC42, RHOA, STARD13
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| StarD13 is a tumor suppressor in breast cancer that regulates cell motility and invasion.
|
| Hanna S, Khalil B, Nasrallah A, Saykali BA, Sobh R, Nasser S, El-Sibai M.
|
| Int J Oncol 44(5):1499-511. doi: 10.3892/ijo.2014.2330. Epub 2014 Mar 7.
2014
|
| 13 | RAC1, RHOA, TRIO
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| Identification of a mitotic Rac-GEF, Trio, that counteracts MgcRacGAP function during cytokinesis.
|
| Cannet A, Schmidt S, Delaval B, Debant A.
|
| Mol Biol Cell 25(25):4063-71. doi: 10.1091/mbc.E14-06-1153. Epub 2014 Oct 29.
2014
|
| 14 | BIRC2, RHOA, XIAP
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| A novel role for inhibitor of apoptosis (IAP) proteins as regulators of endothelial barrier function by mediating RhoA activation.
|
| Hornburger MC, Mayer BA, Leonhardt S, Willer EA, Zahler S, Beyerle A, Rajalingam K, Vollmar AM, Fürst R.
|
| FASEB J 28(4):1938-46. doi: 10.1096/fj.13-235754. Epub 2013 Dec 26. 2014
|
| 15 | CGN, CGNL1, RHOA
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| MgcRacGAP interacts with cingulin and paracingulin to regulate Rac1 activation and development of the tight junction barrier during epithelial junction assembly.
|
| Guillemot L, Guerrera D, Spadaro D, Tapia R, Jond L, Citi S.
|
| Mol Biol Cell 25(13):1995-2005. doi: 10.1091/mbc.E13-11-0680. Epub 2014 May 7.
2014
|
| 16 | RHOA, RHOB, RHOC
|
| RhoA, RhoB and RhoC have different roles in cancer cell migration.
|
| Ridley AJ.
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| J Microsc 251(3):242-9. doi: 10.1111/jmi.12025. Epub 2013 Mar 12.
2013
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| 17 | FN1, NFATC1, RHOA
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| Nuclear factor of activated T cells mediates RhoA-induced fibronectin upregulation in glomerular podocytes.
|
| Zhu L, Qi XY, Aoudjit L, Mouawad F, Baldwin C, Nattel S, Takano T.
|
| Am J Physiol Renal Physiol 304(7):F849-62. doi: 10.1152/ajprenal.00495.2012. Epub 2013 Feb 6.
2013
|
| 18 | DIAPH1, PLECKHG5, RHOA
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| The Rho guanine nucleotide exchange factor Syx regulates the balance of dia and ROCK activities to promote polarized-cancer-cell migration.
|
| Dachsel JC, Ngok SP, Lewis-Tuffin LJ, Kourtidis A, Geyer R, Johnston L, Feathers R, Anastasiadis PZ.
|
| Mol Cell Biol 33(24):4909-18. doi: 10.1128/MCB.00565-13. Epub 2013 Oct 14.
2013
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| 19 | ARHGAP21, RHOA, RHOC
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| ARHGAP21 is a RhoGAP for RhoA and RhoC with a role in proliferation and migration of prostate adenocarcinoma cells.
|
| Lazarini M, Traina F, Machado-Neto JA, Barcellos KS, Moreira YB, Brandão MM, Verjovski-Almeida S, Ridley AJ, Saad ST.
|
| Biochim Biophys Acta 1832(2):365-74. doi: 10.1016/j.bbadis.2012.11.010. Epub 2012 Nov 28.
2013
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| 20 | RHOA, SLC3A2
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| CD98hc (SLC3A2) regulation of skin homeostasis wanes with age.
|
| Boulter E, Estrach S, Errante A, Pons C, Cailleteau L, Tissot F, Meneguzzi G, Féral CC.
|
| J Exp Med 210(1):173-90. doi: 10.1084/jem.20121651. Epub 2013 Jan 7.
2013
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| 21 | ARHGEF18, RHOA, ROCK2
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| ArhGEF18 regulates RhoA-Rock2 signaling to maintain neuro-epithelial apico-basal polarity and proliferation.
|
| Herder C, Swiercz JM, Müller C, Peravali R, Quiring R, Offermanns S, Wittbrodt J, Loosli F.
|
| Development 140(13):2787-97. doi: 10.1242/dev.096487.
2013
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| 22 | ARHGEF18, RHOA, ROCK2
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| ArhGEF18 regulated Rho signaling in vertebrate retina development.
|
| Loosli F.
|
| Small GTPases 4(4):242-6. doi: 10.4161/sgtp.27061. Review.
2013
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| 23 | CES1, RHOA
|
| Control of RhoA methylation by carboxylesterase I.
|
| Cushman I, Cushman SM, Potter PM, Casey PJ.
|
| J Biol Chem 288(26):19177-83. doi: 10.1074/jbc.M113.467407. Epub 2013 May 8.
2013
|
| 24 | FOXO1, RHOA, RIPOR2
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| Fam65b is a new transcriptional target of FOXO1 that regulates RhoA signaling for T lymphocyte migration
|
| Rougerie P, Largeteau Q, Megrelis L, Carrette F, Lejeune T, Toffali L, Rossi B, Zeghouf M, Cherfils J, Constantin G, Laudanna C, Bismuth G, Mangeney M, Delon J
|
| J Immunol. Jan 15;190(2):748-55. doi: 10.4049/jimmunol.1201174. Epub 2012 Dec 14. 2013
|
| 25 | INPPL1, RHOA
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| The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration.
|
| Kato K, Yazawa T, Taki K, Mori K, Wang S, Nishioka T, Hamaguchi T, Itoh T, Takenawa T, Kataoka C, Matsuura Y, Amano M, Murohara T, Kaibuchi K.
|
| Mol Biol Cell 23(13):2593-604. doi: 10.1091/mbc.E11-11-0958. Epub 2012 May 16.
2012
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| 26 | ARHGEF3, RHOA, RHOB
|
| Structure of the Rho-specific guanine nucleotide-exchange factor Xpln.
|
| Murayama K, Kato-Murayama M, Akasaka R, Terada T, Yokoyama S, Shirouzu M.
|
| Acta Crystallogr Sect F Struct Biol Cryst Commun 68(Pt 12):1455-9. doi: 10.1107/S1744309112045265. Epub 2012 Nov 19.
2012
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| 27 | PLD1, RHOA
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| PLD1 Negatively Regulates Dendritic Branching.
|
| Zhu YB, Kang K, Zhang Y, Qi C, Li G, Yin DM, Wang Y.
|
| J Neurosci 32(23):7960-9. doi: 10.1523/JNEUROSCI.5378-11.2012.
2012
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| 28 | PRKD1, PRKD2, PRKD3, RHOA, RTKN
|
| Protein kinase D regulates RhoA activity via rhotekin phosphorylation.
|
| Pusapati GV, Eiseler T, Rykx A, Vandoninck S, Derua R, Waelkens E, Van Lint J, von Wichert G, Seufferlein T.
|
| J Biol Chem 287(12):9473-83. doi: 10.1074/jbc.M112.339564. Epub 2012 Jan 6.
2012
|
| 29 | FYN, RHOA, SLIT2
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| Slit2 regulates the dispersal of oligodendrocyte precursor cells via Fyn/RhoA signaling.
|
| Liu X, Lu Y, Zhang Y, Li Y, Zhou J, Yuan Y, Gao X, Su Z, He C.
|
| J Biol Chem 287(21):17503-16. doi: 10.1074/jbc.M111.317610. Epub 2012 Mar 20.
2012
|
| 30 | F11R, RHOA, ROCK1
|
| Relocalization of junctional adhesion molecule A during inflammatory stimulation of brain endothelial cells.
|
| Stamatovic SM, Sladojevic N, Keep RF, Andjelkovic AV.
|
| Mol Cell Biol 32(17):3414-27. doi: 10.1128/MCB.06678-11. Epub 2012 Jun 25.
2012
|
| 31 | AGAP1, AGAP2, RHOA
|
| GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.
|
| Luo R, Akpan IO, Hayashi R, Sramko M, Barr V, Shiba Y, Randazzo PA.
|
| J Biol Chem 287(21):17176-85. doi: 10.1074/jbc.M111.334458. Epub 2012 Mar 27.
2012
|
| 32 | GMIP, RHOA, SYTL1
|
| Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Gem-interacting protein.
|
| Johnson JL, Monfregola J, Napolitano G, Kiosses WB, Catz SD.
|
| Mol Biol Cell 23(10):1902-16. doi: 10.1091/mbc.E11-12-1001. Epub 2012 Mar 21.
2012
|
| 33 | CDC42, OPHN1, RAC1, RHOA
|
| The GRAF family member oligophrenin1 is a RhoGAP with BAR domain and regulates Rho GTPases in platelets.
|
| Elvers M, Beck S, Fotinos A, Ziegler M, Gawaz M.
|
| Cardiovasc Res 94(3):526-36. doi: 10.1093/cvr/cvs079. Epub 2012 Feb 1.
2012
|
| 34 | RHOA, SYNCRIP
|
| Negative regulation of RhoA translation and signaling by hnRNP-Q1 affects cellular morphogenesis.
|
| Xing L, Yao X, Williams KR, Bassell GJ.
|
| Mol Biol Cell 23(8):1500-9. doi: 10.1091/mbc.E11-10-0867. Epub 2012 Feb 22.
2012
|
| 35 | RHOA
|
| RHOA is a modulator of the cholesterol-lowering effects of statin.
|
| Medina MW, Theusch E, Naidoo D, Bauzon F, Stevens K, Mangravite LM, Kuang YL, Krauss RM.
|
| PLoS Genet 8(11):e1003058. doi: 10.1371/journal.pgen.1003058. Epub 2012 Nov 15. Erratum in: PLoS Genet. 2013 Feb;9(2). doi: 10.1371/annotat 2012
|
| 36 | CDH1, RHOA, SMURF1
|
| The E3 ligase Cdh1-anaphase promoting complex operates upstream of the E3 ligase Smurf1 in the control of axon growth.
|
| Kannan M, Lee SJ, Schwedhelm-Domeyer N, Stegmüller J.
|
| Development 139(19):3600-12. doi: 10.1242/dev.081786.
2012
|
| 37 | IQGAP1, RHOA, RHOB, RHOC
|
| Rho isoform-specific interaction with IQGAP1 promotes breast cancer cell proliferation and migration.
|
| Casteel DE, Turner S, Schwappacher R, Rangaswami H, Su-Yuo J, Zhuang S, Boss GR, Pilz RB.
|
| J Biol Chem 287(45):38367-78. doi: 10.1074/jbc.M112.377499. Epub 2012 Sep 19.
2012
|
| 38 | RHOA
|
| The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool.
|
| Herzog D, Loetscher P, van Hengel J, Knüsel S, Brakebusch C, Taylor V, Suter U, Relvas JB.
|
| J Neurosci. 31(13):5120-30. 2011
|
| 39 | RHOA, SMURF1
|
| Binding of RhoA by the C2 domain of E3 ligase Smurf1 is essential for Smurf1-regulated RhoA ubiquitination and cell protrusive activity.
|
| Tian M, Bai C, Lin Q, Lin H, Liu M, Ding F, Wang HR.
|
| FEBS Lett 585(14):2199-204. Epub 2011 Jun 23.
2011
|
| 40 | ARGAP18, RHOA
|
| ARHGAP18, a GTPase-activating protein for RhoA, controls cell shape, spreading, and motility.
|
| Maeda M, Hasegawa H, Hyodo T, Ito S, Asano E, Yuang H, Funasaka K, Shimokata K, Hasegawa Y, Hamaguchi M, Senga T.
|
| Mol Biol Cell 22(20):3840-52. doi: 10.1091/mbc.E11-04-0364. Epub 2011 Aug 24.
2011
|
| 41 | ARHGEF3, RHOA
|
| Silencing of RhoA nucleotide exchange factor, ARHGEF3, reveals its unexpected role in iron uptake.
|
| Serbanovic-Canic J, Cvejic A, Soranzo N, Stemple DL, Ouwehand WH, Freson K.
|
| Blood 118(18):4967-76. doi: 10.1182/blood-2011-02-337295. Epub 2011 Jun 28.
2011
|
| 42 | CIT, RHOA
|
| Sticky/Citron kinase maintains proper RhoA localization at the cleavage site during cytokinesis.
|
| Bassi ZI, Verbrugghe KJ, Capalbo L, Gregory S, Montembault E, Glover DM, D'Avino PP.
|
| J Cell Biol 195(4):595-603. doi: 10.1083/jcb.201105136.
2011
|
| 43 | RHOA, RHOC, ROCK2
|
| RhoA and RhoC are both required for the ROCK II-dependent promotion of centrosome duplication.
|
| Kanai M, Crowe MS, Zheng Y, Vande Woude GF, Fukasawa K.
|
| Oncogene 29(45):6040-50. doi: 10.1038/onc.2010.328. Epub 2010 Aug 9.
2010
|
| 44 | RHOA, RHOB, RHOC
|
| Rho isoforms have distinct and specific functions in the process of epithelial to mesenchymal transition in renal proximal tubular cells.
|
| Hutchison N, Hendry BM, Sharpe CC.
|
| Cell Signal 21(10):1522-31. Epub 2009 May 27.PMID: 19477269 2009
|
| 45 | MYH9, PLEKHG6, RHOA, RHOC
|
| Myosin-interacting guanine exchange factor (MyoGEF) regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC.
|
| Wu D, Asiedu M, Wei Q.
|
| Oncogene 28(22):2219-30.PMID: 19421144 2009
|
| 46 | CDH1, RAC1, RHOA, RHOB
|
| Rac1 and Rho contribute to the migratory and invasive phenotype associated with somatic E-cadherin mutation.
|
| Deplazes J, Fuchs M, Rauser S, Genth H, Lengyel E, Busch R, Luber B.
|
| Hum Mol Genet 18(19):3632-44. Epub 2009 Jul 7.PMID: 19584084 2009
|
| 47 | ARHGEF10, KIF3B, RHOA
|
| Regulation of mitotic spindle formation by the RhoA guanine nucleotide exchange factor ARHGEF10.
|
| Aoki T, Ueda S, Kataoka T, Satoh T.
|
| BMC Cell Biol 10:56.PMID: 19635168 2009
|
| 48 | DIAPH1, RHOA
|
| RhoA effector mDia1 is required for PI 3-kinase-dependent actin remodeling and spreading by thrombin in platelets.
|
| Gao G, Chen L, Dong B, Gu H, Dong H, Pan Y, Gao Y, Chen X.
|
| Biochem Biophys Res Commun 385(3):439-44. Epub 2009 May 24.
2009
|
| 49 | CYTH1, RHOA
|
| Cytohesin-1 controls the activation of RhoA and modulates integrin-dependent adhesion and migration of dendritic cells.
|
| Quast T, Tappertzhofen B, Schild C, Grell J, Czeloth N, Förster R, Alon R, Fraemohs L, Dreck K, Weber C, Lämmermann T, Sixt M, Kolanus W.
|
| Blood 113(23):5801-10. Epub 2009 Apr 3.
2009
|
| 50 | ARHGDIA, RHOA, RHOB
|
| RhoA-GDP regulates RhoB protein stability. Potential involvement of RhoGDIalpha.
|
| Ho TT, Merajver SD, Lapière CM, Nusgens BV, Deroanne CF.
|
| J Biol Chem 283(31):21588-98. Epub 2008 Jun 4.
2008
|
| 51 | PLEKHG6, PLK1, RHOA
|
| Phosphorylation of MyoGEF on Thr-574 by Plk1 promotes MyoGEF localization to the central spindle.
|
| Asiedu M, Wu D, Matsumura F, Wei Q.
|
| J Biol Chem 283(42):28392-400. Epub 2008 Aug 11.PMID: 18694934 2008
|
| 52 | CGNL1, RAC1, RHOA
|
| Paracingulin regulates the activity of Rac1 and RhoA GTPases by recruiting Tiam1 and GEF-H1 to epithelial junctions.
|
| Guillemot L, Paschoud S, Jond L, Foglia A, Citi S.
|
| Mol Biol Cell 19(10):4442-53. Epub 2008 Jul 23.
2008
|
| 53 | DIAPH1, MEMO1, RHOA
|
| Memo-RhoA-mDia1 signaling controls microtubules, the actin network, and adhesion site formation in migrating cells.
|
| Zaoui K, Honoré S, Isnardon D, Braguer D, Badache A.
|
| J Cell Biol 183(3):401-8. Epub 2008 Oct 27.
2008
|
| 54 | ANLN, RHOA
|
| Anillin is a scaffold protein that links RhoA, actin, and myosin during cytokinesis.
|
| Piekny AJ, Glotzer M.
|
| Curr Biol 18(1):30-6. Epub 2007 Dec 27.
2008
|
| 55 | CIT, RHOA, TTC3
|
| The Down syndrome critical region protein TTC3 inhibits neuronal differentiation via RhoA and Citron kinase.
|
| Berto G, Camera P, Fusco C, Imarisio S, Ambrogio C, Chiarle R, Silengo L, Di Cunto F.
|
| J Cell Sci 120(Pt 11):1859-67. Epub 2007 May 8.
2007
|
| 56 | RHOA
|
| Activation of ROCK by RhoA is regulated by cell adhesion, shape, and cytoskeletal tension.
|
| Bhadriraju K, Yang M, Alom Ruiz S, Pirone D, Tan J, Chen CS.
|
| Exp Cell Res 313(16):3616-23. Epub 2007 Jul 10.
2007
|
| 57 | ECT2, PKP4, RHOA
|
| Beyond regulation of cell adhesion: local control of RhoA at the cleavage furrow by the p0071 catenin.
|
| Keil R, Wolf A, Hüttelmaier S, Hatzfeld M.
|
| Cell Cycle 6(2):122-7. Epub 2007 Jan 19. Review.
2007
|
| 58 | ECT2, RHOA
|
| Centralspindlin regulates ECT2 and RhoA accumulation at the equatorial cortex during cytokinesis.
|
| Nishimura Y, Yonemura S.
|
| J Cell Sci 119(Pt 1):104-14. Epub 2005 Dec 13. 2006
|
| 59 | NEDD9, RHOA
|
| Deregulation of HEF1 impairs M-phase progression by disrupting the RhoA activation cycle.
|
| Dadke D, Jarnik M, Pugacheva EN, Singh MK, Golemis EA.
|
| Mol Biol Cell 17(3):1204-17. Epub 2006 Jan 4. 2006
|
| 60 | MYHG, PLEKHG6, RHOA
|
| A novel guanine nucleotide exchange factor MyoGEF is required for cytokinesis.
|
| Wu D, Asiedu M, Adelstein RS, Wei Q.
|
| Cell Cycle 5(11):1234-9. Epub 2006 Jun 1.PMID: 16721066 2006
|
| 61 | ARF1, ARPC2, ARPC3, RHOA, ARHGAP21
|
| Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics.
|
| Dubois T, Paleotti O, Mironov AA, Fraisier V, Stradal TE, De Matteis MA, Franco M, Chavrier P.
|
| Nat Cell Biol 7(4):353-64. Epub 2005 Mar 27. 2005
|
| 62 | ECT2, RHOA
|
| An ECT2-centralspindlin complex regulates the localization and function of RhoA.
|
| YŸce O, Piekny A, Glotzer M.
|
| J Cell Biol 170(4):571-82. 2005
|
| 63 | CDC42, RHOA
|
| DEF6, a novel PH-DH-like domain protein, is an upstream activator of the Rho GTPases Rac1, Cdc42, and RhoA.
|
| Mavrakis KJ, McKinlay KJ, Jones P, Sablitzky F.
|
| Exp Cell Res. 294(2):335-44. 2004
|
| 64 | CDC42, RHOA
|
| Protein profile of tax-associated complexes.
|
| Wu K, Bottazzi ME, de la Fuente C, Deng L, Gitlin SD, Maddukuri A, Dadgar S, Li H, Vertes A, Pumfery A, Kashanchi F.
|
| J Biol Chem. 279(1):495-508. 2004
|
| 65 | RHOA, RHOC
|
| Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma.
|
| Horiuchi A, Imai T, Wang C, Ohira S, Feng Y, Nikaido T, Konishi I.
|
| Lab Invest 83(6):861-70. 2003
|
| 66 | MPRIP, RHOA
|
| Myosin phosphatase-Rho interacting protein. A new member of the myosin phosphatase complex that directly binds RhoA.
|
| Surks HK, Richards CT, Mendelsohn ME.
|
| J Biol Chem 278(51):51484-93. Epub 2003 Sep 23. 2003
|
| 67 | RAC1, RAP1GDS1, RHOA
|
| Novel mechanism of the co-regulation of nuclear transport of SmgGDS and Rac1.
|
| Lanning CC, Ruiz-Velasco R, Williams CL.
|
| J Biol Chem 278(14):12495-506. Epub 2003 Jan 27.PMID: 12551911 2003
|
| 68 | RHOA
|
| RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability.
|
| Mehta D, Ahmmed GU, Paria BC, Holinstat M, Voyno-Yasenetskaya T, Tiruppathi C, Minshall RD, Malik AB.
|
| J Biol Chem. 278(35):33492-500. 2003
|
| 69 | RHOA
|
| Protective role of HSP72 against Clostridium difficile toxin A-induced intestinal epithelial cell dysfunction.
|
| Liu TS, Musch MW, Sugi K, Walsh-Reitz MM, Ropeleski MJ, Hendrickson BA, Pothoulakis C, Lamont JT, Chang EB.
|
| Am J Physiol Cell Physiol. 284(4):C1073-82 2003
|
| 70 | RHOA, RHPN1, RHPN2
|
| The RhoA-binding protein, rhophilin-2, regulates actin cytoskeleton organization.
|
| Peck JW, Oberst M, Bouker KB, Bowden E, Burbelo PD.
|
| J Biol Chem 277(46):43924-32. Epub 2002 Sep 06. 2002
|
| 71 | RHOA, CRMP1, DPYSL2
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| p80 ROKalpha binding protein is a novel splice variant of CRMP-1 which associates with CRMP-2 and modulates RhoA-induced neuronal morphology.
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| Leung T, Ng Y, Cheong A, Ng CH, Tan I, Hall C, Lim L.
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| FEBS Lett 532(3):445-9. 2002
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| 72 | ARHGEF3, RHOA
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| XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC.
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| Arthur WT, Ellerbroek SM, Der CJ, Burridge K, Wennerberg K.
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| J Biol Chem 277(45):42964-72. Epub 2002 Sep 06. 2002
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| 73 | RHOA, RAC1, RTN4
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| Nogo-A and myelin-associated glycoprotein mediate neurite growth inhibition by antagonistic regulation of RhoA and Rac1.
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| Niederost B, Oertle T, Fritsche J, McKinney RA, Bandtlow CE.
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| J Neurosci 22(23):10368-76. 2002
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| 74 | KRAS, RAC1, RAP1GDS1, RHOA
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| SmgGDS displays differential binding and exchange activity towards different Ras isoforms.
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| Vikis HG, Stewart S, Guan KL.
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| Oncogene 21(15):2425-32.PMID: 11948427 2002
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| 75 | RHOA
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| Leukotriene D4 induces association of active RhoA with phospholipase C-gamma1 in intestinal epithelial cells.
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| Thodeti CK, Massoumi R, Bindslev L, Sjölander A.
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| Biochem J. 365(Pt 1):157-63. 2002
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| 76 | RHOA
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| Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA.
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| Reuther GW, Lambert QT, Booden MA, Wennerberg K, Becknell B, Marcucci G, Sondek J, Caligiuri MA, Der CJ.
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| J Biol Chem. 276(29):27145-51. 2001
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| 77 | RHOA
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| Determination of interaction sites of phospholipase D1 for RhoA.
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| Cai S, Exton JH.
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| Biochem J. 355(Pt 3):779-85. 2001
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| 78 | RHOA
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| Role of transglutaminase II in retinoic acid-induced activation of RhoA-associated kinase-2.
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| Singh US, Kunar MT, Kao YL, Baker KM.
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| EMBO J. 20(10):2413-23. 2001
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| 79 | RHOA, RHOB, RHOC, RHOG
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| Motility and invasion are differentially modulated by Rho family GTPases.
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| Banyard J, Anand-Apte B, Symons M, Zetter BR.
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| Oncogene 19(4):580-91. 2000
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| 80 | RHOA, RHOB, RHOC, RHOG
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| Rho family proteins in cell adhesion and cell migration.
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| Evers EE, Zondag GC, Malliri A, Price LS, ten Klooster JP, van der Kammen RA, Collard JG.
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| Eur J Cancer 36(10):1269-74. Review. 2000
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| 81 | RHOA
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| The trio guanine nucleotide exchange factor is a RhoA target. Binding of RhoA to the trio immunoglobulin-like domain.
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| Medley QG, Serra-Pagès C, Iannotti E, Seipel K, Tang M, O'Brien SP, Streuli M.
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| J Biol Chem. 275(46):36116-23. 2000
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| 82 | RHOA, RHOB, RHOC, RHOG
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| Rho-like GTPases: their role in epithelial cell-cell adhesion and invasion.
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| Sander EE, Collard JG.
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| Eur J Cancer 35(14):1905-11. Review. 1999
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| 83 | RHOA
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| Diacylglycerol kinase theta binds to and is negatively regulated by active RhoA.
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| Houssa B, de Widt J, Kranenburg O, Moolenaar WH, van Blitterswijk WJ.
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| J Biol Chem. 274(11):6820-2. 1999
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| 84 | RHOA, TIAM1
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| Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling.
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| Stam JC, Michiels F, van der Kammen RA, Moolenaar WH, Collard JG.
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| EMBO J 17(14):4066-74. 1998
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| 85 | CDC42, RHOA
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| Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7.
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| Alberts AS, Bouquin N, Johnston LH, Treisman R.
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| J Biol Chem. 273(15):8616-22. 1998
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| 86 | RHOA
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| Localization of RhoA GTPase to endothelial caveolae-enriched membrane domains.
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| Gingras D, Gauthier F, Lamy S, Desrosiers RR, Béliveau R.
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| Biochem Biophys Res Commun. 247(3):888-93. 1998
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| 87 | RHOA
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| Multiple interactions of PRK1 with RhoA. Functional assignment of the Hr1 repeat motif.
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| Flynn P, Mellor H, Palmer R, Panayotou G, Parker PJ.
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| J Biol Chem. 273(5):2698-705. 1998
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| 88 | RHOA, GPX1
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| Assignment of the ARHA and GPX1 genes to human chromosome bands 3p21.3 by in situ hybridization and with somatic cell hybrids.
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| Kiss C, Li J, Szeles A, Gizatullin RZ, Kashuba VI, Lushnikova T, Protopopov AI, Kelve M, Kiss H, Kholodnyuk ID, Imreh S, Klein G, Zabarovsky ER.
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| Cytogenet Cell Genet 79 : 228-230. 1997
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| 89 | RHOA
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| Structural determinants required for the interaction between Rho GTPase and the GTPase-activating domain of p190.
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| Li R, Zhang B, Zheng Y.
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| J Biol Chem. 272(52):32830-5. 1997
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| 90 | RHOA
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| Identification of a novel, putative Rho-specific GDP/GTP exchange factor and a RhoA-binding protein: control of neuronal morphology.
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| Gebbink MF, Kranenburg O, Poland M, van Horck FP, Houssa B, Moolenaar WH.
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| J Cell Biol. 137(7):1603-13. 1997
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| 91 | RHOA, RTKN
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| Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain.
|
| Reid T, Furuyashiki T, Ishizaki T, Watanabe G, Watanabe N, Fujisawa K, Morii N, Madaule P, Narumiya S.
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| J Biol Chem. 271(23):13556-60. 1996
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| 92 | RHOA, RHOB, RHOC, RHOD, RHOG, RAC1, RAC2, RAC3
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| Activation of the small GTP-binding proteins rho and rac by growth factor receptors.
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| Nobes CD, Hawkins P, Stephens L, Hall A.
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| J Cell Sci 108 ( Pt 1):225-33. 1995
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| 93 | RHOA, RHOB, RHOC, RHOD, RHOG
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| The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors.
|
| Ridley AJ, Hall A.
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| Cell 70(3):389-99. 1992
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| 94 | RHOA, RHOB, RHOC
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| Chromosome localization of human ARH genes, a ras-related gene family.
|
| Cannizzaro LA, et al.
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| Genomics 6 : 197-203. 1990
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