1 | ADAM17, FRMD8, RHBDF1, RHBDF2
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| FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.
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| Künzel U, Grieve AG, Meng Y, Sieber B, Cowley SA, Freeman M.
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| Elife 7. pii: e35012. doi: 10.7554/eLife.35012.
2018
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2 | ADAM17, FRMD8, RHBDF1, RHBDF2
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| iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.
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| Oikonomidi I, Burbridge E, Cavadas M, Sullivan G, Collis B, Naegele H, Clancy D, Brezinova J, Hu T, Bileck A, Gerner C, Bolado A, von Kriegsheim A, Martin SJ, Steinberg F, Strisovsky K, Adrain C.
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| Elife 7. pii: e35032. doi: 10.7554/eLife.35032.
2018
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3 | RHBDF1, RHBDF2, TOC
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| RHBDF2 Mutations Are Associated with Tylosis, a Familial Esophageal Cancer Syndrome.
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| Blaydon DC, Etheridge SL, Risk JM, Hennies HC, Gay LJ, Carroll R, Plagnol V, McRonald FE, Stevens HP, Spurr NK, Bishop DT, Ellis A, Jankowski J, Field JK, Leigh IM, South AP, Kelsell DP.
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| Am J Hum Genet 90(2):340-6. Epub 2012 Jan 19.
2012
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4 | RHBDF1
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| Human rhomboid family-1 gene RHBDF1 participates in GPCR-mediated transactivation of EGFR growth signals in head and neck squamous cancer cells.
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| Zou H, Thomas SM, Yan ZW, Grandis JR, Vogt A, Li LY.
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| FASEB J 23(2):425-32. Epub 2008 Oct 2.
2009
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5 | RHBDF1
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| Human rhomboid family-1 gene silencing causes apoptosis or autophagy to epithelial cancer cells and inhibits xenograft tumor growth.
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| Yan Z, Zou H, Tian F, Grandis JR, Mixson AJ, Lu PY, Li LY.
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| Mol Cancer Ther 7(6):1355-64. Epub 2008 Jun 4.
2008
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6 | RHBDF1
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| Characterization of a human rhomboid homolog, p100hRho/RHBDF1, which interacts with TGF-alpha family ligands.
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| Nakagawa T, Guichard A, Castro CP, Xiao Y, Rizen M, Zhang HZ, Hu D, Bang A, Helms J, Bier E, Derynck R.
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| Dev Dyn 233(4):1315-31.
2005
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7 | RHBDF1, ATHAL, LCR-HBA@
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| Homology of a 130-kb region enclosing the alpha-globin gene cluster, the alpha-locus controlling region, and two non-globin genes in human and mouse.
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| Kielman MF, Smits R, Devi TS, Fodde R, Bernini LF.
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| Mamm Genome 4(6):314-23. 1993
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