Citations for
1GPR158, RGS11, RGS6, RGS7, RGS9
Regulator of G-protein Signaling 7 (RGS7) can exist in a homo-oligomeric form that is regulated by Gαo and R7-binding protein.
Tayou J, Wang Q, Jang GF, Pronin AN, Orlandi C, Martemyanov KA, Crabb JW, Slepak VZ.
J Biol Chem Biol Chem. 2016 Feb 19. pii: jbc.M115.694075. [Epub ahead of print] 2016
2RGS7
Regulator of G-Protein Signaling 7 Regulates Reward Behavior by Controlling Opioid Signaling in the Striatum.
Sutton LP, Ostrovskaya O, Dao M, Xie K, Orlandi C, Smith R, Wee S, Martemyanov KA.
Biol Psychiatry iol Psychiatry. 2015 Aug 14. pii: S0006-3223(15)00653-8. doi: 10.1016/j.biopsych.2015.07.026. [Epub ahead of print] 2015
3GPR158, RGS7
Orphan Receptor GPR158 Is an Allosteric Modulator of RGS7 Catalytic Activity with an Essential Role in Dictating Its Expression and Localization in the Brain.
Orlandi C, Xie K, Masuho I, Fajardo-Serrano A, Lujan R, Martemyanov KA.
J Biol Chem 290(22):13622-39. doi: 10.1074/jbc.M115.645374. Epub 2015 Mar 19. 2015
4RGS7, RGS7BP
RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling.
Ostrovskaya O, Xie K, Masuho I, Fajardo-Serrano A, Lujan R, Wickman K, Martemyanov KA.
Elife 3:e02053. doi: 10.7554/eLife.02053. 2014
5DRD2, GNB5, RGS7
G protein beta 5 is targeted to D2-dopamine receptor-containing biochemical compartments and blocks dopamine-dependent receptor internalization.
Octeau JC, Schrader JM, Masuho I, Sharma M, Aiudi C, Chen CK, Kovoor A, Celver J.
PLoS One 9(8):e105791. doi: 10.1371/journal.pone.0105791. eCollection 2014. 2014
6GPR179, GRM6, RGS11, RGS7, TRPM1
GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells.
Ray TA, Heath KM, Hasan N, Noel JM, Samuels IS, Martemyanov KA, Peachey NS, McCall MA, Gregg RG.
J Neurosci 34(18):6334-43. doi: 10.1523/JNEUROSCI.4044-13.2014. 2014
7GPR179, GRM6, RGS11, RGS7, TRPM1
GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells.
Ray TA, Heath KM, Hasan N, Noel JM, Samuels IS, Martemyanov KA, Peachey NS, McCall MA, Gregg RG.
J Neurosci 34(18):6334-43. doi: 10.1523/JNEUROSCI.4044-13.2014. 2014
8GRM6, RGS11, RGS7
Regulators of G protein signaling RGS7 and RGS11 determine the onset of the light response in ON bipolar neurons.
Cao Y, Pahlberg J, Sarria I, Kamasawa N, Sampath AP, Martemyanov KA.
Proc Natl Acad Sci U S A 109(20):7905-10. doi: 10.1073/pnas.1202332109. Epub 2012 Apr 30. 2012
9RGS11, RGS7
Subcellular localization of regulator of G protein signaling RGS7 complex in neurons and transfected cells.
Liapis E, Sandiford S, Wang Q, Gaidosh G, Motti D, Levay K, Slepak VZ.
J Neurochem 122(3):568-81. doi: 10.1111/j.1471-4159.2012.07811.x. Epub 2012 Jun 22. 2012
10GNB5, RGS7
Defective retinal depolarizing bipolar cells in regulators of G protein signaling (RGS) 7 and 11 double null mice.
Shim H, Wang CT, Chen YL, Chau VQ, Fu KG, Yang J, McQuiston AR, Fisher RA, Chen CK.
J Biol Chem 287(18):14873-9. doi: 10.1074/jbc.M112.345751. Epub 2012 Feb 27. 2012
11GNB5, RGS7
Expression of the Gβ5/R7-RGS protein complex in pituitary and pancreatic islet cells.
Nini L, Zhang JH, Pandey M, Panicker LM, Simonds WF.
Endocrine 42(1):214-7. doi: 10.1007/s12020-012-9611-5. Epub 2012 Feb 10. No abstract available. 2012
12GNB5, RGS7
Gβ5-RGS complexes are gatekeepers of hyperactivity involved in control of multiple neurotransmitter systems.
Xie K, Ge S, Collins VE, Haynes CL, Renner KJ, Meisel RL, Lujan R, Martemyanov KA.
Psychopharmacology (Berl) 219(3):823-34. doi: 10.1007/s00213-011-2409-y. Epub 2011 Jul 16. 2012
13GNB5, RGS7
Gbeta5 recruits R7 RGS proteins to GIRK channels to regulate the timing of neuronal inhibitory signaling.
Xie K, Allen KL, Kourrich S, Colón-Saez J, Thomas MJ, Wickman K, Martemyanov KA.
Nat Neurosci 13(6):661-3. doi: 10.1038/nn.2549. Epub 2010 May 9. 2010
14GNB5, RGS7, RGS7BP
Nuclear localization of the G protein beta 5/R7-regulator of G protein signaling protein complex is dependent on R7 binding protein.
Panicker LM, Zhang JH, Posokhova E, Gastinger MJ, Martemyanov KA, Simonds WF.
J Neurochem 113(5):1101-12. doi: 10.1111/j.1471-4159.2010.06616.x. Epub 2010 Jan 22. 2010
15RGS11, RGS6, RGS7, RGS9
The R7 RGS protein family: multi-subunit regulators of neuronal G protein signaling.
Anderson GR, Posokhova E, Martemyanov KA.
Cell Biochem Biophys 54(1-3):33-46. Epub 2009 Jun 12. Review. 2009
16GNB5, PDCL, RGS7
Role of molecular chaperones in G protein beta5/regulator of G protein signaling dimer assembly and G protein betagamma dimer specificity.
Howlett AC, Gray AJ, Hunter JM, Willardson BM.
J Biol Chem 284(24):16386-99. doi: 10.1074/jbc.M900800200. Epub 2009 Apr 17. 2009
17GNB5, RGS7, RGS7BP
Changes in striatal signaling induce remodeling of RGS complexes containing Gbeta5 and R7BP subunits.
Anderson GR, Lujan R, Martemyanov KA.
Mol Cell Biol 29(11):3033-44. doi: 10.1128/MCB.01449-08. Epub 2009 Mar 30. 2009
18GNB5, RGS11, RGS7
Two R7 regulator of G-protein signaling proteins shape retinal bipolar cell signaling.
Mojumder DK, Qian Y, Wensel TG.
J Neurosci 29(24):7753-65. doi: 10.1523/JNEUROSCI.1794-09.2009. 2009
19GNB5, RGS7, RGS7BP
Postnatal induction and localization of R7BP, a membrane-anchoring protein for regulator of G protein signaling 7 family-Gbeta5 complexes in brain.
Grabowska D, Jayaraman M, Kaltenbronn KM, Sandiford SL, Wang Q, Jenkins S, Slepak VZ, Smith Y, Blumer KJ.
Neuroscience 151(4):969-82. doi: 10.1016/j.neuroscience.2007.11.045. Epub 2007 Dec 8. 2008
20GNB5, RGS7, RGS7BP
R7BP augments the function of RGS7*Gbeta5 complexes by a plasma membrane-targeting mechanism.
Drenan RM, Doupnik CA, Jayaraman M, Buchwalter AL, Kaltenbronn KM, Huettner JE, Linder ME, Blumer KJ.
J Biol Chem 281(38):28222-31. Epub 2006 Jul 25. 2006
21RGS1, RGS11, RGS12, RGS13, RGS17, RGS18, RGS4, RGS7, RGS8, RGS9
Selective expression of regulators of G-protein signaling (RGS) in the human central nervous system.
Larminie C, Murdock P, Walhin JP, Duckworth M, Blumer KJ, Scheideler MA, Garnier M.
Brain Res Mol Brain Res 122(1):24-34. 2004
22RGS10, RGS13, RGS18, RGS19, RGS4, RGS7
Evolution of the regulators of G-protein signaling multigene family in mouse and human.
Sierra DA, Gilbert DJ, Householder D, Grishin NV, Yu K, Ukidwe P, Barker SA, He W, Wensel TG, Otero G, Brown G, Copeland NG, Jenkins NA, Wilkie TM.
Genomics 79(2):177-85. 2002
23GNB5, RGS7
Nuclear localization of G protein beta 5 and regulator of G protein signaling 7 in neurons and brain.
Zhang JH, Barr VA, Mo Y, Rojkova AM, Liu S, Simonds WF.
J Biol Chem 276(13):10284-9. 2001