| 1 | ACE, AGT, AGTR1, REN, RTD1, RTD2, RTD3, RTD4
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| Spectrum of mutations in the renin-angiotensin system genes in autosomal recessive renal tubular dysgenesis.
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| Gribouval O, Moriničre V, Pawtowski A, Arrondel C, Sallinen SL, Saloranta C, Clericuzio C, Viot G, Tantau J, Blesson S, Cloarec S, Machet MC, Chitayat D, Thauvin C, Laurent N, Sampson JR, Bernstein JA, Clemenson A, Prieur F, Daniel L, Levy-Mozziconacci A, Lachlan K, Alessandri JL, Cartault F, Rivičre JP, Picard N, Baumann C, Delezoide AL, Belar Ortega M, Chassaing N, Labrune P, Yu S, Firth H, Wellesley D, Bitzan M, Alfares A, Braverman N, Krogh L, Tolmie J, Gaspar H, Doray B, Majore S, Bonneau D, Triau S, Loirat C, David A, Bartholdi D, Peleg A, Brackman D, Stone R, DeBerardinis R, Corvol P, Michaud A, Antignac C, Gubler MC.
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| Hum Mutat 33(2):316-26. doi: 10.1002/humu.21661. Epub 2011 Dec 22. Review.
2012
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| 2 | REN, RTD4
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| Loss-of-function point mutations associated with renal tubular dysgenesis provide insights about renin function and cellular trafficking.
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| Michaud A, Bur D, Gribouval O, Muller L, Iturrioz X, Clemessy M, Gasc JM, Gubler MC, Corvol P.
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| Hum Mol Genet 20(2):301-11. Epub 2010 Oct 29.
2011
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| 3 | REN, UAKD2
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| Dominant renin gene mutations associated with early-onset hyperuricemia, anemia, and chronic kidney failure.
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| Zivná M, Hůlková H, Matignon M, Hodanová K, Vylet'al P, Kalbácová M, Baresová V, Sikora J, Blazková H, Zivný J, Ivánek R, Stránecký V, Sovová J, Claes K, Lerut E, Fryns JP, Hart PS, Hart TC, Adams JN, Pawtowski A, Clemessy M, Gasc JM, Gübler MC, Antignac C, Elleder M, Kapp K, Grimbert P, Bleyer AJ, Kmoch S.
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| Am J Hum Genet 85(2):204-13. Epub 2009 Aug 6.
2009
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| 4 | REN
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| Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide.
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| Feldt S, Batenburg WW, Mazak I, Maschke U, Wellner M, Kvakan H, Dechend R, Fiebeler A, Burckle C, Contrepas A, Jan Danser AH, Bader M, Nguyen G, Luft FC, Muller DN.
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| Hypertension 51(3):682-8. Epub 2008 Jan 22. 2008
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| 5 | RTD1, AGT, AGTR1, ACE, RTD2, REN, RTD4, RTD3
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| Inherited renal tubular dysgenesis: the first patients surviving the neonatal period.
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| Zingg-Schenk A, Bacchetta J, Corvol P, Michaud A, Stallmach T, Cochat P, Gribouval O, Gubler MC, Neuhaus TJ.
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| Eur J Pediatr [Epub ahead of print] 2007
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| 6 | REN
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| Functional characterization of polymorphisms in the kidney enhancer of the human renin gene.
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| Itani HA, Liu X, Pratt JH, Sigmund CD.
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| Endocrinology 148(3):1424-30. Epub 2006 Dec 7.
2007
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| 7 | REN
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| Renin enhancer is critical for control of renin gene expression and cardiovascular function.
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| Adams DJ, Head GA, Markus MA, Lovicu FJ, van der Weyden L, Kšntgen F, Arends MJ, Thiru S, Mayorov DN, Morris BJ.
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| J Biol Chem 281(42):31753-61. Epub 2006 Aug 8. Erratum in: J Biol Chem. 2006 Dec 29;281(52):40527. 2006
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| 8 | RTD1, AGT, AGTR1, ACE, RTD2, REN, RTD4, RTD3
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| Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis.
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| Gribouval O, Gonzales M, Neuhaus T, Aziza J, Bieth E, Laurent N, Bouton JM, Feuillet F, Makni S, Ben Amar H, Laube G, Delezoide AL, Bouvier R, Dijoud F, Ollagnon-Roman E, Roume J, Joubert M, Antignac C, Gubler MC.
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| Nat Genet 37(9):964-8. Epub 2005 Aug 14. 2005
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| 9 | REN, NR2F6
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| Identification of a nuclear orphan receptor (Ear2) as a negative regulator of renin gene transcription.
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| Liu X, Huang X, Sigmund CD.
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| Circ Res 92(9):1033-40. Epub 2003 Apr 10. 2003
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| 10 | REN, ELAVL1, PCBP1, HADHB
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| HADHB, HuR, and CP1 bind to the distal 3'-untranslated region of human renin mRNA and differentially modulate renin expression.
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| Adams DJ, Beveridge DJ, van der Weyden L, Mangs H, Leedman PJ, Morris BJ.
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| J Biol Chem 278(45):44894-903. Epub 2003 Aug 21. 2003
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| 11 | REN
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| A mutant renin gene in familial elevation of prorenin.
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| Villard E, et al.
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| J Biol Chem 269 : 30307-30312. 1994
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| 12 | FABP2, AR, TH, REN, HPRT1
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| Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groups.
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| Edwards A, et al.
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| Genomics 12 : 241-253. 1992
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| 13 | CTSE, REN
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| Physical ordering for CTSE and REN on chromosome 1 using two-color fluorescent in situ hybridization.
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| Inazawa J, et al.
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| (HGM11) Cytogenet Cell Genet 58 : 1856. 1991
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| 14 | F13B, REN, SPTA1
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| The B subunit of coagulation factor XIII is linked to renin and the Duffy blood group to alpha-spectrin on human chromosome 1.
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| Griffiths LR, Board PG, Zwi MB, Morris BJ, McLeod JG, Nicholson GA.
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| Hum Hered 39 : 107-109. 1989
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| 15 | REN
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| HinfI RFLP at the human renin (REN) gene locus.
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| Masharani U.
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| Nucleic Acids Res 17 : 467. 1989
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| 16 | REN
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| Regional mapping of the human renin gene to 1q32 by in situ hybridization.
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| Cohen-Haguenauer O, et al.
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| Ann Genet 32 : 16-20. 1989
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| 17 | REN
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| Human renin gene assigned to chromosome band 1q42 by in situ hybridization.
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| Nakai H, et al.
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| Cytogenet Cell Genet 47 : 90-91. 1988
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| 18 | REN, PTPRC, LAMC1, APOA2, SPTA1
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| Establishment of a molecular genetic map of distal mouse chromosome 1: further definition of a conserved linkage group syntenic with human chromosome 1q.
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| Seldin MF, Morse HC, LeBoeuf RC, Steinberg AD.
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| Genomics 2(1):48-56. 1988
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| 19 | REN
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| MboI RFLP at the human renin (ren) gene locus.
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| Masharani U, et al.
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| Nucleic Acids Res 16 : 2357. 1988
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| 20 | REN
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| Linkage of Van der Woude syndrome to markers on chromosome 1q and exclusion of laminin B2 as a candidate gene.
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| Murray JC, et al.
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| Am J Hum Genet 43 : A153. 1988
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| 21 | REN
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| Two Eco T14I RFLPs at the human renin (REN) gene locus.
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| Masharani U, et al.
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| Nucleic Acids Res 16 : 6253. 1988
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| 22 | REN
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| Chromosome localization of the human renin gene (REN) by in situ hybridization.
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| McGill JR, et al.
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| Cytogenet Cell Genet 45 : 55-57. 1987
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| 23 | REN
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| Confirmation of the chromosomal assignment of the renin gene to human chromosome 1 and regional assignment using in situ hybridization.
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| Cohen-Haguenauer O, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 597. 1987
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| 24 | REN
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| Human renin (REN) gene locus : BgIII, RsaI and TaqI RFLPs.
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| Frossard PM, et al.
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| Nucleic Acids Res 14 : 6778. 1986
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| 25 | REN
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| Two RFLPs at the human renin (ren) gene locus.
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| Frossard PM, et al.
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| Nucleic Acids Res 14 : 4380. 1986
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| 26 | REN
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| Human renin gene is located on chromosome 1.
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| Naylor SL, et al.
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| (HGM7) Cytogenet Cell Genet 37 : 549-550. 1984
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| 27 | REN
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| Human renin gene is on chromosome 1.
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| Chirgwin JM, et al.
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| Somat Cell Mol Genet 10 : 415-421. 1984
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