Citations for
1REL, RELB, TNFSF13B
B-cell survival and development controlled by the coordination of NF-κB family members RelB and cRel.
Almaden JV, Liu YC, Yang E, Otero DC, Birnbaum H, Davis-Turak J, Asagiri M, David M, Goldrath AW, Hoffmann A.
Blood 127(10):1276-86. doi: 10.1182/blood-2014-10-606988. Epub 2016 Jan 14. 2016
2FOXP3, JUNB, REL
JunB and c-Rel cooperatively enhance Foxp3 expression during induced regulatory T cell differentiation.
Son JS, Sahoo A, Chae CS, Hwang JS, Park ZY, Im SH.
Biochem Biophys Res Commun 407(1):141-7. Epub 2011 Mar 1. 2011
3IL2, IL4, IRF4, REL
Interferon regulatory factor-4 activates IL-2 and IL-4 promoters in cooperation with c-Rel.
Shindo H, Yasui K, Yamamoto K, Honma K, Yui K, Kohno T, Ma Y, Chua KJ, Kubo Y, Aihara H, Ito T, Nagayasu T, Matsuyama T, Hayashi H.
Cytokine 56(3):564-72. doi: 10.1016/j.cyto.2011.08.014. Epub 2011 Sep 3. 2011
4CLSPN, IKBKB, IKBKG, REL
IKK and NF-kappaB-mediated regulation of Claspin impacts on ATR checkpoint function.
Kenneth NS, Mudie S, Rocha S.
EMBO J 29(17):2966-78. Epub 2010 Jul 23. 2010
5IL21, REL
Regulation of the IL-21 gene by the NF-kappaB transcription factor c-Rel.
Chen G, Hardy K, Bunting K, Daley S, Ma L, Shannon MF.
J Immunol 185(4):2350-9. Epub 2010 Jul 16. 2010
6REL
c-Rel but not NF-kappaB1 is important for T regulatory cell development.
Deenick EK, Elford AR, Pellegrini M, Hall H, Mak TW, Ohashi PS.
Eur J Immunol 40(3):677-81. 2010
7GATA3, PVT1, REL
A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3).
Enciso-Mora V, Broderick P, Ma Y, Jarrett RF, Hjalgrim H, Hemminki K, van den Berg A, Olver B, Lloyd A, Dobbins SE, Lightfoot T, van Leeuwen FE, Försti A, Diepstra A, Broeks A, Vijayakrishnan J, Shield L, Lake A, Montgomery D, Roman E, Engert A, von Strandmann EP, Reiners KS, Nolte IM, Smedby KE, Adami HO, Russell NS, Glimelius B, Hamilton-Dutoit S, de Bruin M, Ryder LP, Molin D, Sorensen KM, Chang ET, Taylor M, Cooke R, Hofstra R, Westers H, van Wezel T, van Eijk R, Ashworth A, Rostgaard K, Melbye M, Swerdlow AJ, Houlston RS.
Nat Genet 42(12):1126-30. Epub 2010 Oct 31. 2010
8REL
REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
Gregersen PK, Amos CI, Lee AT, Lu Y, Remmers EF, Kastner DL, Seldin MF, Criswell LA, Plenge RM, Holers VM, Mikuls TR, Sokka T, Moreland LW, Bridges SL Jr, Xie G, Begovich AB, Siminovitch KA.
Nat Genet 41(7):820-3. Epub 2009 Jun 7. 2009
9REL
c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells.
Isomura I, Palmer S, Grumont RJ, Bunting K, Hoyne G, Wilkinson N, Banerjee A, Proietto A, Gugasyan R, Wu L, McNally A, Steptoe RJ, Thomas R, Shannon MF, Gerondakis S.
J Exp Med 206(13):3001-14. Epub 2009 Dec 7. Erratum in: J Exp Med.2010 Apr 12;207(4):899. Li, Wu [corrected to Wu, Li]. 2009
10REL, RELA
Divergent roles of RelA and c-Rel in establishing chromosomal loops upon activation of the Igkappa gene.
Liu Z, Ma Z, Terada LS, Garrard WT.
J Immunol 183(6):3819-30. Epub 2009 Aug 26. 2009
11REL
c-Rel, an NF-kappaB family transcription factor, is required for hippocampal long-term synaptic plasticity and memory formation.
Ahn HJ, Hernandez CM, Levenson JM, Lubin FD, Liou HC, Sweatt JD.
Learn Mem 15(7):539-49. Print 2008. 2008
12REL
c-Rel is essential for the development of innate and T cell-induced colitis.
Wang Y, Rickman BH, Poutahidis T, Schlieper K, Jackson EA, Erdman SE, Fox JG, Horwitz BH.
J Immunol 180(12):8118-25. 2008
13RBM39, REL
CAPERalpha is a novel Rel-TAD-interacting factor that inhibits lymphocyte transformation by the potent Rel/NF-kappaB oncoprotein v-Rel.
Dutta J, Fan G, Gélinas C.
J Virol 82(21):10792-802. doi: 10.1128/JVI.00903-08. Epub 2008 Aug 27. 2008
14REL
Gene expression analysis of angioimmunoblastic lymphoma indicates derivation from T follicular helper cells and vascular endothelial growth factor deregulation.
Piccaluga PP, Agostinelli C, Califano A, Carbone A, Fantoni L, Ferrari S, Gazzola A, Gloghini A, Righi S, Rossi M, Tagliafico E, Zinzani PL, Zupo S, Baccarani M, Pileri SA.
Cancer Res 67(22):10703-10. 2007
15CEBPB, CRP, REL
The interaction of C-Rel with C/EBPbeta enhances C/EBPbeta binding to the C-reactive protein gene promoter.
Cha-Molstad H, Young DP, Kushner I, Samols D.
Mol Immunol 44(11):2933-42. Epub 2007 Feb 28. 2007
16IKBKA, REL
Mutation of an IKK phosphorylation site within the transactivation domain of REL in two patients with B-cell lymphoma enhances REL's in vitro transforming activity.
Starczynowski DT, Trautmann H, Pott C, Harder L, Arnold N, Africa JA, Leeman JR, Siebert R, Gilmore TD.
Oncogene 26(19):2685-94. Epub 2006 Oct 30. 2007
17REL
Differential expression patterns of c-REL protein in classic and nodular lymphocyte predominant Hodgkin lymphoma.
Xiao Q, Shen N, Hedvat CV, Moskowitz CH, Sussman LK, Filippa DA, Zelenetz AD, Houldsworth J, Chaganti RS, Teruya-Feldstein J.
Appl Immunohistochem Mol Morphol 12(3):211-5. 2004
18REL, RELA, CALM1
Regulation of c-Rel nuclear localization by binding of Ca2+/calmodulin.
Antonsson A, Hughes K, Edin S, Grundstršm T.
Mol Cell Biol 23(4):1418-27. 2003
19BCL11A, REL
Genomic organization and expression of the rearranged REL proto-oncogene in the human B-cell lymphoma cell line RC-K8.
Kalaitzidis D, Gilmore TD.
Genes Chromosomes Cancer 34(1):129-35. 2002
20JAG1, NFKB1, NFKB2, REL
Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors.
Bash J, et al.
EMBO J 18(10):2803-2811. 1999
21BCL2, BCL8, BRINP1, CDK4, GLI1, MDM2, MYC, REL
Chromosomal and gene amplification in diffuse large B-cell lymphoma.
Rao PH, et al.
Blood 92 : 234-240. 1998
22LGMD2B, MEIS1, MDH1, RAB1A, REL, OTX1, D2S357, D2S2701, D2S337, D2S1745, D2S2090
Homology between human chromosome 2p13.3 and the wobbler critical region on mouse chromosome 11 : comparative high-resolution mapping of STS and EST loci on YAC/BAC contigs.
Resch K, et al.
Mamm Genome 9 : 893-898. 1998
23REL, NFKB1, NFKB2, RELA
Chromosomal localization of genes encoding the transcription factors, c-rel, NF-kappaBp50, NF-kappaBp65, and lyt-10 by fluorescence in situ hybridization.
Mathew S, et al.
Oncogene 8 : 191-193. 1993
24REL
The v-rel oncogene encodes a KB enhancer binding protein that inhibits NF-KB function.
Ballard DW, et al.
Cell 63 : 803-814. 1990
25REL
NF-kB, KBF1, dorsal, and related matters.
Gilmore TD.
Cell 62 : 841-843. 1990
26REL
Comparative genetic mapping of cellular rel sequences in man, mouse and the domestic cat.
Brownell E, et al.
Am J Hum Genet 39 : 194-202. 1986
27REL
Isolation and chromosomal localization of human cellular REL sequences.
Brownell E, et al.
(HGM8) Cytogenet Cell Genet 40 : 591. 1985