| 1 | REG1A
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| Pancreatic Stone Protein in the Diagnosis of Sepsis in Children Admitted to High-Dependency Care: A Single-Center Prospective Cohort Study.
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| Bottari G, Paionni E, Fegatelli DA, Murciano M, Rosati F, Ferrigno F, Pisani M, Cristaldi S, Musolino A, Borrelli G, Bochicchio C, Romani L, De Luca M, Agosta M, Lancella L, Villani A, Vestri A, Atti MCD, Perno CF, Porzio O, Raponi M, Cecchetti C.
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| Pediatr Crit Care Med. Oct 1;25(10):937-946. doi: 10.1097/PCC.0000000000003565. Epub 2024 Jul 18. 2024
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| 2 | REG1A
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| REG1A protects retinal photoreceptors from blue light damage.
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| Xu ZH, Zhang H, Zhang CJ, Yu SJ, Yuan J, Jin K, Jin ZB.
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| Ann N Y Acad Sci. Sep;1527(1):60-74. doi: 10.1111/nyas.15045. Epub 2023 Aug 2. 2023
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| 3 | REG1A
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| Protective and anti-inflammatory role of REG1A in inflammatory bowel disease induced by JAK/STAT3 signaling axis.
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| Mao H, Jia J, Sheng J, Zhang S, Huang K, Li H, He F.
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| Int Immunopharmacol. Mar;92:107304. doi: 10.1016/j.intimp.2020.107304. Epub 2021 Jan 26. 2021
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| 4 | REG1A
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| Pancreatic stone protein/regenerating protein is a potential biomarker for endoplasmic reticulum stress in beta cells.
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| Stone S, Abreu D, Mahadevan J, Asada R, Kries K, Graf R, Marshall BA, Hershey T, Urano F.
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| Sci Rep. Mar 26;9(1):5199. doi: 10.1038/s41598-019-41604-4. 2019
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| 5 | REG1A
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| Association of Serum PSP/REG Iα with Renal Function in Pregnant Women.
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| Zhu X, Dong B, Reding T, Peng Y, Lin H, Zhi M, Han M, Graf R, Li L.
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| Biomed Res Int. Apr 21;2019:6970890. doi: 10.1155/2019/6970890. 2019
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| 6 | REG1A
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| DNA Methylation-Mediated Silencing of Regenerating Protein 1 Alpha (REG1A) Affects Gastric Cancer Prognosis.
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| Qiu YS, Liao GJ, Jiang NN.
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| Med Sci Monit. Dec 9;23:5834-5843. doi: 10.12659/msm.904706. 2017
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| 7 | REG1A
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| Decreased REG1α expression suppresses growth, invasion and angiogenesis of bladder cancer.
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| Geng J, Fan J, Wang Q, Zhang XP, Kang L, Li QY, Xu YF, Peng B, Zheng JH, Yao XD.
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| Eur J Surg Oncol. Apr;43(4):837-846. doi: 10.1016/j.ejso.2017.01.013. Epub 2017 Feb 2. 2017
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| 8 | CLDN3, CLDN4, REG1A
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| Role of regenerating gene I in claudin expression and barrier function in the small intestine.
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| Kitayama Y, Fukui H, Hara K, Eda H, Kodani M, Yang M, Sun C, Yamagishi H, Tomita T, Oshima T, Watari J, Takasawa S, Miwa H.
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| Transl Res. Jul;173:92-100. doi: 10.1016/j.trsl.2016.03.007. Epub 2016 Mar 19. 2016
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| 9 | REG1A
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| Epigenetic regulation of REG1A and chemosensitivity of cutaneous melanoma.
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| Sato Y, Marzese DM, Ohta K, Huang SK, Sim MS, Chong K, Hoon DS.
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| Epigenetics 8(10):1043-52. doi: 10.4161/epi.25810. Epub 2013 Jul 31.
2013
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| 10 | REG1A
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| Involvement of autoimmunity to REG, a regeneration factor, in patients with primary Sjögren's syndrome.
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| Yoshimoto K, Fujimoto T, Itaya-Hironaka A, Miyaoka T, Sakuramoto-Tsuchida S, Yamauchi A, Takeda M, Kasai T, Nakagawara K, Nonomura A, Takasawa S.
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| Clin Exp Immunol 174(1):1-9. doi: 10.1111/cei.12142.
2013
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| 11 | PSMB1, REG1A, SERPINB2
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| The role of proteasome beta subunits in gastrin-mediated transcription of plasminogen activator inhibitor-2 and regenerating protein1.
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| O'Hara A, Howarth A, Varro A, Dimaline R.
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| PLoS One. ;8(3):e59913. doi: 10.1371/journal.pone.0059913. Epub 2013 Mar 27. 2013
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| 12 | EXTL3, REG1A
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| Regenerating islet-derived 1α (Reg-1α) protein is new neuronal secreted factor that stimulates neurite outgrowth via exostosin Tumor-like 3 (EXTL3) receptor.
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| Acquatella-Tran Van Ba I, Marchal S, François F, Silhol M, Lleres C, Michel B, Benyamin Y, Verdier JM, Trousse F, Marcilhac A.
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| J Biol Chem 287(7):4726-39. doi: 10.1074/jbc.M111.260349. Epub 2011 Dec 9.
2012
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| 13 | REG1A
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| Regenerating gene (REG) 1 alpha promotes pannus progression in patients with rheumatoid arthritis.
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| Fujishiro M, Nozawa K, Kawasaki M, Yamaguchi A, Iwabuchi K, Yanagida M, Suzuki F, Miyazawa K, Fukui H, Kaneko K, Ogawa H, Takamori K, Takasaki Y, Sekigawa I.
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| Mod Rheumatol 22(2):228-37. doi: 10.1007/s10165-011-0564-y. Epub 2011 Dec 28.
2012
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| 14 | REG1A
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| Regenerating gene Iα is a biomarker for diagnosis and monitoring of celiac disease: a preliminary study.
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| Planas R, Pujol-Autonell I, Ruiz E, Montraveta M, Cabre E, Lucas-Martin A, Pujol-Borrell R, Martinez-Caceres E, Vives-Pi M.
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| Transl Res 158(3):140-5. doi: 10.1016/j.trsl.2011.04.004. Epub 2011 May 30.
2011
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| 15 | REG1A
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| Upregulation of REG Ialpha accelerates tumor progression in pancreatic cancer with diabetes.
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| Zhou L, Zhang R, Wang L, Shen S, Okamoto H, Sugawara A, Xia L, Wang X, Noguchi N, Yoshikawa T, Uruno A, Yao W, Yuan Y.
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| Int J Cancer 127(8):1795-803. doi: 10.1002/ijc.25188.
2010
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| 16 | REG1A
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| Circulating Reg1α proteins and autoantibodies to Reg1α proteins as biomarkers of β-cell regeneration and damage in type 1 diabetes.
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| Astorri E, Guglielmi C, Bombardieri M, Alessandri C, Buzzetti R, Maggi D, Valesini G, Pitzalis C, Pozzilli P.
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| Horm Metab Res 42(13):955-60. doi: 10.1055/s-0030-1267206. Epub 2010 Oct 22.
2010
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| 17 | REG1A
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| Expression and localization of regenerating gene I in a rat liver regeneration model.
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| Wang J, Koyota S, Zhou X, Ueno Y, Ma L, Kawagoe M, Koizumi Y, Okamoto H, Sugiyama T.
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| Biochem Biophys Res Commun 380(3):472-7. doi: 10.1016/j.bbrc.2009.01.126. Epub 2009 Jan 27.
2009
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| 18 | REG1A
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| REG Ialpha protein expression in Barrett's esophagus.
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| Chinuki D, Amano Y, Ishihara S, Moriyama N, Ishimura N, Kazumori H, Kadowaki Y, Takasawa S, Okamoto H, Kinoshita Y.
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| J Gastroenterol Hepatol 23(2):296-302.PMID: 18289358 2008
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| 19 | REG1A
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| REG Ialpha protein mediates an anti-apoptotic effect of STAT3 signaling in gastric cancer cells.
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| Sekikawa A, Fukui H, Fujii S, Ichikawa K, Tomita S, Imura J, Chiba T, Fujimori T.
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| Carcinogenesis 29(1):76-83. Epub 2007 Nov 16.
2008
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| 20 | REG1A
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| Activation of regenerating gene Reg in rat and human hearts in response to acute stress.
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| Kiji T, Dohi Y, Takasawa S, Okamoto H, Nonomura A, Taniguchi S.
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| Am J Physiol Heart Circ Physiol 289(1):H277-84. Epub 2005 Mar 18.
2005
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| 21 | REG3G, REG1B, REG1A, REGL, REG3A
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| Molecular cloning, expression and chromosomal localization of a novel human REG family gene, REG III.
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| Nata K, Liu Y, Xu L, Ikeda T, Akiyama T, Noguchi N, Kawaguchi S, Yamauchi A, Takahashi I, Shervani NJ, Onogawa T, Takasawa S, Okamoto H.
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| Gene 340(1):161-70. 2004
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| 22 | CD74, DEFA5, DEFA6, ESD, CXCL1, IGHG3, IGLL2, LCN2, REG3A, PI3, REG1A, S100A9, S100P
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| Ulcerative colitis and Crohn's disease : distinctive gene expression profiles and novel susceptibility candidate genes.
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| Lawrance IC, Fiocchi C, Chakravarti S.
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| Hum Mol Genet 10(5):445-56. 2001
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| 23 | REG1A
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| Human REG I gene is up-regulated in intrahepatic cholangiocarcinoma and its precursor lesions.
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| Harada K, Zen Y, Kanemori Y, Chen TC, Chen MF, Yeh TS, Jan YY, Masuda S, Nimura Y, Takasawa S, Okamoto H, Nakanuma Y.
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| Hepatology 33(5):1036-42. 2001
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| 24 | EXTL3, REG1A
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| Identification of a receptor for reg (regenerating gene) protein, a pancreatic beta-cell regeneration factor.
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| Kobayashi S, Akiyama T, Nata K, Abe M, Tajima M, Shervani NJ, Unno M, Matsuno S, Sasaki H, Takasawa S, Okamoto H.
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| J Biol Chem 275(15):10723-6. 2000
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| 25 | REG1A, REG1B, REGL
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| A limited genomic region contains the human REG and REG-related genes.
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| Bartoli C, et al.
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| Eur J Hum Genet 3 : 344-350. 1995
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| 26 | REG1A, REG1B, REGL
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| Human REG family genes are tandemly ordered in a 95-kilobase region of chromosome 2p12.
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| Miyashita H, et al.
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| FEBS Lett 377 : 429-433. 1995
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| 27 | REG1A
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| Assignment of the human pancreatic regenerating (REG) gene to chromosome2p12.
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| Perfetti R, et al.
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| Genomics 20 : 305-307. 1994
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| 28 | REG1A, REG1B
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| Isolation, structural determination and expression of a novel reg gene, human reg I beta.
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| Moriizumi S, et al.
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| Biochim Biophys Acta 1217 : 199-202. 1994
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| 29 | REG1A
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| Pancreatic beta-cell replication and amelioration of surgical diabetes by Reg protein.
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| Watanabe T, et al.
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| Proc Natl Acad Sci U S A 91 : 3589-3592. 1994
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| 30 | REG1A, REG1B
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| Human regeneration protein/lithostathine genes map to chromosome 2p12.
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| Gharib B, et al.
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| Ann Hum Genet 57 : 9-16. 1993
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| 31 | REG1A
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| Complete nucleotide sequence of the human REG gene and its expression innormal and tumoral tissues : the REG protein, pancreatic stone protein, and pancreatic thread protein are one and the same product of the gene.
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| Watanabe T, et al.
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| J Biol Chem 265 : 7432-7439. 1990
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| 32 | REG1A
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| Enhanced expression of an exocrine pancreatic protein in Alzheimer's disease and the developing human brain.
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| de la Monte SM, Ozturk M, Wands JR.
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| J Clin Invest 86(3):1004-13.
1990
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