| 1 | ATL, KIF5A, KIF5B, KIF5C, PLP1, REEP1, REEP5, ZFYVE27
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| Protrudin regulates endoplasmic reticulum morphology and function associated with the pathogenesis of hereditary spastic paraplegia.
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| Hashimoto Y, Shirane M, Matsuzaki F, Saita S, Ohnishi T, Nakayama KI.
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| J Biol Chem 289(19):12946-61. doi: 10.1074/jbc.M113.528687. Epub 2014 Mar 25.
2014
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| 2 | REEP1, REEP2, REEP3, REEP4, REEP5, REEP6
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| REEPs are membrane shaping adapter proteins that modulate specific g protein-coupled receptor trafficking by affecting ER cargo capacity.
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| Björk S, Hurt CM, Ho VK, Angelotti T.
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| PLoS One 8(10):e76366. doi: 10.1371/journal.pone.0076366. eCollection 2013. Erratum in: PLoS One. 2013;8(12). doi:10.1371/annotation/6f86 2013
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| 3 | LETMD1, REEP5
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| HCCR-1-interacting molecule deleted in polyposis 1 plays a tumor-suppressor role in colon carcinogenesis.
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| Shin SM, Chung YJ, Oh ST, Jeon HM, Hwang LJ, Namkoong H, Kim HK, Cho GW, Hur SY, Kim TE, Lee YS, Park YG, Ko J, Kim JW.
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| Gastroenterology 130(7):2074-86. 2006
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| 4 | REEP5
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| The murine homolog of TB2/DP1, a gene of the familial adenomatous polyposis (FAP) locus.
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| Prieschl EE, Pendl GG, Harrer NE, Baumruker T.
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| Gene 169(2):215-8. 1996
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| 5 | APC, D5S141, MCC, SRP19, REEP5
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| Identification of FAP locus genes from chromosome 5q21.
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| Kinzler KW, Nilbert MC, Su LK, Vogelstein B, Bryan TM, Levy DB, Smith KJ,Preisinger AC, Hedge P, McKechnie D, et al.
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| Science 253(5020):661-5. 1991
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| 6 | SRP19, APC, REEP5, FAP
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| Identification of deletion mutations and three new genes at the familial polyposis locus.
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| Joslyn G, Carlson M, Thliveris A, Albertsen H, Gelbert L, Samowitz W,Groden J, Stevens J, Spirio L, Robertson M, et al.
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| Cell 66(3):601-13. 1991
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| 7 | APC, FAP, REEP5, SLC25A46
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| Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients.
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| Nishisho I, Nakamura Y, Miyoshi Y, Miki Y, Ando H, Horii A, Koyama K, Utsunomiya J, Baba S, Hedge P.
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| Science 253(5020):665-9. 1991
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