1 | PROM1, RDX
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| Prominin-1-Radixin axis controls hepatic gluconeogenesis by regulating PKA activity.
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| Lee H, Yu DM, Park JS, Lee H, Kim JS, Kim HL, Koo SH, Lee JS, Lee S, Ko YG.
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| EMBO Rep Nov 5;21(11):e49416. doi: 10.15252/embr.201949416. Epub 2020 Oct 8. 2020
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2 | EZR, MSN, NF2, RDX
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| Two Sides of the Coin: Ezrin/Radixin/Moesin and Merlin Control Membrane Structure and Contact Inhibition.
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| Michie KA, Bermeister A, Robertson NO, Goodchild SC, Curmi PMG.
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| Int J Mol Sci 20(8). pii: E1996. doi: 10.3390/ijms20081996. Review.
2019
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3 | EZR, MSN, RDX
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| Dynamics and function of ERM proteins during cytokinesis in human cells.
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| Hiruma S, Kamasaki T, Otomo K, Nemoto T, Uehara R.
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| FEBS Lett 591(20):3296-3309. doi: 10.1002/1873-3468.12844. Epub 2017 Sep 20.
2017
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4 | PRG2, RDX
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| Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling.
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| Cheng J, Sahani S, Hausrat TJ, Yang JW, Ji H, Schmarowski N, Endle H, Liu X, Li Y, Böttche R, Radyushkin K, Maric HM, Hoerder-Suabedissen A, Molnár Z, Prouvot PH, Trimbuch T, Ninnemann O, Huai J, Fan W, Visentin B, Sabbadini R, Strømgaard K, Stroh A, Luhmann HJ, Kneussel M, Nitsch R, Vogt J.
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| Neuron 92(1):126-142. doi: 10.1016/j.neuron.2016.08.035. Epub 2016 Sep 15.
2016
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5 | GABRA5, RDX
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| Radixin regulates synaptic GABAA receptor density and is essential for reversal learning and short-term memory.
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| Hausrat TJ, Muhia M, Gerrow K, Thomas P, Hirdes W, Tsukita S, Heisler FF, Herich L, Dubroqua S, Breiden P, Feldon J, Schwarz JR, Yee BK, Smart TG, Triller A, Kneussel M.
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| Nat Commun 6:6872. doi: 10.1038/ncomms7872.
2015
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6 | EZR, MSN, RDX
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| Inhibition of cell adhesion by phosphorylated Ezrin/Radixin/Moesin.
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| Tachibana K, Haghparast SM, Miyake J.
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| Cell Adh Migr 9(6):502-12. doi: 10.1080/19336918.2015.1113366.
2015
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7 | EZR, MSN, RDX
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| Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies?
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| Miyaji K, Shahrizaila N, Umapathi T, Chan YC, Hirata K, Yuki N.
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| Hum Immunol 75(11):1089-91. doi: 10.1016/j.humimm.2014.09.010. Epub 2014 Oct 5.
2014
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8 | EZR, MSN, PDGFA, RDX
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| Redundant control of migration and adhesion by ERM proteins in vascular smooth muscle cells.
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| Baeyens N, Latrache I, Yerna X, Noppe G, Horman S, Morel N.
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| Biochem Biophys Res Commun 441(3):579-85. doi: 10.1016/j.bbrc.2013.10.118. Epub 2013 Oct 30.
2013
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9 | RDX
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| Contribution of radixin to P-glycoprotein expression and transport activity in mouse small intestine in vivo.
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| Yano K, Tomono T, Sakai R, Kano T, Morimoto K, Kato Y, Ogihara T.
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| J Pharm Sci 102(8):2875-81. doi: 10.1002/jps.23637. Epub 2013 Jun 10.
2013
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10 | RDX
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| Radixin expression in microglia after cortical stroke lesion.
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| Persson Å, Osman A, Bolouri H, Mallard C, Kuhn HG.
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| Glia 61(5):790-9. doi: 10.1002/glia.22473. Epub 2013 Feb 26.
2013
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11 | EZR, MSN, P2RX7, RDX
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| Ezrin/radixin/moesin are required for the purinergic P2X7 receptor (P2X7R)-dependent processing of the amyloid precursor protein.
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| Darmellah A, Rayah A, Auger R, Cuif MH, Prigent M, Arpin M, Alcover A, Delarasse C, Kanellopoulos JM.
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| J Biol Chem 287(41):34583-95. doi: 10.1074/jbc.M112.400010. Epub 2012 Aug 13.
2012
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12 | EZR, MSN, RAC1, RDX
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| Radixin regulates cell migration and cell-cell adhesion through Rac1.
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| Valderrama F, Thevapala S, Ridley AJ.
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| J Cell Sci 125(Pt 14):3310-9. doi: 10.1242/jcs.094383. Epub 2012 Mar 30.
2012
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13 | EZR, MSN, RAS, RDX
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| Activation of Ras requires the ERM-dependent link of actin to the plasma membrane.
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| Sperka T, Geissler KJ, Merkel U, Scholl I, Rubio I, Herrlich P, Morrison HL.
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| PLoS One 6(11):e27511. doi: 10.1371/journal.pone.0027511. Epub 2011 Nov 21.
2011
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14 | EZR, MSN, RDX
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| Emerging role for ERM proteins in cell adhesion and migration.
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| Arpin M, Chirivino D, Naba A, Zwaenepoel I.
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| Cell Adh Migr 5(2):199-206. Epub 2011 Mar 1. Review.
2011
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15 | EZR, MSN, RDX
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| Expression of ezrin radixin moesin proteins in the adult subventricular zone and the rostral migratory stream.
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| Persson A, Lindwall C, Curtis MA, Kuhn HG.
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| Neuroscience 167(2):312-22. doi: 10.1016/j.neuroscience.2010.01.035. Epub 2010 Jan 28.
2010
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16 | DFNB24, RDX
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| A novel splice site mutation in the RDX gene causes DFNB24 hearing loss in an Iranian family.
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| Shearer AE, Hildebrand MS, Bromhead CJ, Kahrizi K, Webster JA, Azadeh B, Kimberling WJ, Anousheh A, Nazeri A, Stephan D, Najmabadi H, Smith RJ, Bahlo M.
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| Am J Med Genet A 149A(3):555-8. No abstract available.
2009
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17 | RDX, DFNB24
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| Mutations of the RDX gene cause nonsyndromic hearing loss at the DFNB24 locus.
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| Khan SY, Ahmed ZM, Shabbir MI, Kitajiri S, Kalsoom S, Tasneem S, Shayiq S, Ramesh A, Srisailpathy S, Khan SN, Smith RJ, Riazuddin S, Friedman TB, Riazuddin S.
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| Hum Mutat 28(5):417-23. 2007
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18 | CLIC5, RDX
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| The chloride intracellular channel protein CLIC5 is expressed at high levels in hair cell stereocilia and is essential for normal inner ear function.
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| Gagnon LH, Longo-Guess CM, Berryman M, Shin JB, Saylor KW, Yu H, Gillespie PG, Johnson KR.
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| J Neurosci 26(40):10188-98. 2006
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19 | RDX
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| Radixin is a constituent of stereocilia in hair cells.
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| Pataky F, Pironkova R, Hudspeth AJ.
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| Proc Natl Acad Sci U S A 101(8):2601-6. 2004
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20 | ITGB1, MSN, PRKCA, RDX, EZR
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| Ezrin is a downstream effector of trafficking PKC-integrin complexes involved in the control of cell motility.
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| Ng T, Parsons M, Hughes WE, Monypenny J, Zicha D, Gautreau A, Arpin M, Gschmeissner S, Verveer PJ, Bastiaens PI, Parker PJ.
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| EMBO J 20(11):2723-2741. 2001
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21 | MSN, RDX, EZR
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| Ezrin, radixin, and moesin are components of Schwann cell microvilli.
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| Scherer SS, Xu T, Crino P, Arroyo EJ, Gutmann DH.
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| J Neurosci Res 65(2):150-64. 2001
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22 | RDX
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| Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.
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| Hamada K, Shimizu T, Matsui T, Tsukita S, Hakoshima T.
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| EMBO J 19(17):4449-4462. 2000
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23 | MSN, RDX
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| Moesin, the major ERM protein of lymphocytes and platelets, differs from ezrin in its insensitivity to calpain.
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| Shcherbina A, et al.
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| FEBS Lett 443(1):31-6. 1999
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24 | EPB41, EPB41L2, KRIT1, MSN, MYO15A, MYO7A, NF2, PTPN14, PTPN21, PTPN3, RDX, EZR
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| The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membrane.
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| Chishti AH, Kim AC, Marfatia SM, Lutchman M, Hanspal M, Jindal H, Liu SC, Low PS, Rouleau GA, Mohandas N, Chasis JA, Conboy JG, Gascard P, Takakuwa Y, Huang SC, Benz EJ Jr, Bretscher A, Fehon RG, Gusella JF, Ramesh V, Solomon F, Marchesi VT, Tsukita S, Tsukita S, Hoover KB, et al.
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| Trends Biochem Sci 23(8):281-2. Review. No abstract available 1998
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25 | RDX, RDXP1, RDXP2
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| Molecular cloning, cDNA sequence, and chromosomal assignment of the human radixin gene and two dispersed pseudogenes.
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| Wilgenbus KK, et al.
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| Genomics 16 : 199-206. 1993
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26 | EPB41, MSN, NF2, PTPN13, PTPN3, RDX, TLN1, EZR
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| A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites.
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| Sato N, et al.
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| J Cell Sci 103 : 131-143. 1992
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