Citations for
1RC3H1, RC3H2
Roquin2 suppresses breast cancer progression by inhibiting tumor angiogenesis via selectively destabilizing proangiogenic factors mRNA
Zhou M, Lu W, Li B, Yuan X, Liu M, Han J, Liu X, Li A.
Int J Biol Sci. Jul 13;17(11):2884-2898. doi: 10.7150/ijbs.59891 2021
2NUFIP2, RC3H1, RC3H2
Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA.
Rehage N, Davydova E, Conrad C, Behrens G, Maiser A, Stehklein JE, Brenner S, Klein J, Jeridi A, Hoffmann A, Lee E, Dianzani U, Willemsen R, Feederle R, Reiche K, Hackermüller J, Leonhardt H, Sharma S, Niessing D, Heissmeyer V.
Nat Commun. Jan 19;9(1):299. doi: 10.1038/s41467-017-02582-1. 2018
3RC3H1, RC3H2
New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities of Roquins.
Zhang Q, Fan L, Hou F, Dong A, Wang YX, Tong Y.
Sci Rep. Oct 22;5:15660. doi: 10.1038/srep15660. 2015
4RC3H2
Structure of human Roquin-2 and its complex with constitutive-decay element RNA
Sakurai S, Ohto U, Shimizu T.
. Acta Crystallogr F Struct Biol Commun. Aug;71(Pt 8):1048-54. doi: 10.1107/S2053230X15011887. Epub 2015 Jul 29. 2015
5MAP3K5, RC3H2
Roquin-2 promotes ubiquitin-mediated degradation of ASK1 to regulate stress responses.
Maruyama T, Araki T, Kawarazaki Y, Naguro I, Heynen S, Aza-Blanc P, Ronai Z, Matsuzawa A, Ichijo H.
Sci Signal 7(309):ra8. doi: 10.1126/scisignal.2004822. 2014
6RC3H1, RC3H2
Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation.
Vogel KU, Edelmann SL, Jeltsch KM, Bertossi A, Heger K, Heinz GA, Zöller J, Warth SC, Hoefig KP, Lohs C, Neff F, Kremmer E, Schick J, Repsilber D, Geerlof A, Blum H, Wurst W, Heikenwälder M, Schmidt-Supprian M, Heissmeyer V.
Immunity 38(4):655-68. doi: 10.1016/j.immuni.2012.12.004. Epub 2013 Apr 11. 2013
7RC3H1, RC3H2
Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation.
Pratama A, Ramiscal RR, Silva DG, Das SK, Athanasopoulos V, Fitch J, Botelho NK, Chang PP, Hu X, Hogan JJ, Maña P, Bernal D, Korner H, Yu D, Goodnow CC, Cook MC, Vinuesa CG.
Immunity 38(4):669-80. doi: 10.1016/j.immuni.2013.01.011. Epub 2013 Apr 11. 2013
8RC3H2, OR1K1
A human gene coding for a membrane-associated nucleic acid-binding protein.
Siess DC, Vedder CT, Merkens LS, Tanaka T, Freed AC, McCoy SL, Heinrich MC, Deffebach ME, Bennett RM, Hefeneider SH.
J Biol Chem 275(43):33655-62. 2000