1 | MAP3K5, RC3H2
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| Roquin-2 promotes ubiquitin-mediated degradation of ASK1 to regulate stress responses.
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| Maruyama T, Araki T, Kawarazaki Y, Naguro I, Heynen S, Aza-Blanc P, Ronai Z, Matsuzawa A, Ichijo H.
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| Sci Signal 7(309):ra8. doi: 10.1126/scisignal.2004822.
2014
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2 | RC3H1, RC3H2
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| Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation.
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| Vogel KU, Edelmann SL, Jeltsch KM, Bertossi A, Heger K, Heinz GA, Zöller J, Warth SC, Hoefig KP, Lohs C, Neff F, Kremmer E, Schick J, Repsilber D, Geerlof A, Blum H, Wurst W, Heikenwälder M, Schmidt-Supprian M, Heissmeyer V.
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| Immunity 38(4):655-68. doi: 10.1016/j.immuni.2012.12.004. Epub 2013 Apr 11.
2013
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3 | RC3H1, RC3H2
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| Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation.
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| Pratama A, Ramiscal RR, Silva DG, Das SK, Athanasopoulos V, Fitch J, Botelho NK, Chang PP, Hu X, Hogan JJ, Maña P, Bernal D, Korner H, Yu D, Goodnow CC, Cook MC, Vinuesa CG.
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| Immunity 38(4):669-80. doi: 10.1016/j.immuni.2013.01.011. Epub 2013 Apr 11.
2013
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4 | RC3H2, OR1K1
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| A human gene coding for a membrane-associated nucleic acid-binding protein.
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| Siess DC, Vedder CT, Merkens LS, Tanaka T, Freed AC, McCoy SL, Heinrich MC, Deffebach ME, Bennett RM, Hefeneider SH.
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| J Biol Chem 275(43):33655-62. 2000
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