Citations for
1RBFOX1, RBFOX2, RBFOX3
Rbfox family proteins make the homo- and hetero-oligomeric complexes.
Choi S, Kim YE, Kim JW, Cho N, Cheon S, Kim KK.
Biochem Biophys Res Commun 495(1):1022-1027. doi: 10.1016/j.bbrc.2017.11.128. Epub 2017 Nov 21. 2018
2FLNB, QKI, RBFOX1
An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer
Li J, Choi PS, Chaffer CL, Labella K, Hwang JH, Giacomelli AO, Kim JW, Ilic N, Doench JG, Ly SH, Dai C, Hagel K, Hong AL, Gjoerup O, Goel S, Ge JY, Root DE, Zhao JJ, Brooks AN, Weinberg RA, Hahn WC.
Elife. Jul 30;7:e37184. doi: 10.7554/eLife.37184. 2018
3RBFOX1
Heterogeneous contribution of microdeletions in the development of common generalised and focal epilepsies.
Pérez-Palma E, Helbig I, Klein KM, Anttila V, Horn H, Reinthaler EM, Gormley P, Ganna A, Byrnes A, Pernhorst K, Toliat MR, Saarentaus E, Howrigan DP, Hoffman P, Miquel JF, De Ferrari GV, Nürnberg P, Lerche H, Zimprich F, Neubauer BA, Becker AJ, Rosenow F, Perucca E, Zara F, Weber YG, Lal D.
J Med Genet 54(9):598-606. doi: 10.1136/jmedgenet-2016-104495. Epub 2017 Jul 29. 2017
4RBFOX1
Rare variants in fox-1 homolog A (RBFOX1) are associated with lower blood pressure.
He KY, Wang H, Cade BE, Nandakumar P, Giri A, Ware EB, Haessler J, Liang J, Smith JA, Franceschini N, Le TH, Kooperberg C, Edwards TL, Kardia SL, Lin X, Chakravarti A, Redline S, Zhu X.
PLoS Genet 13(3):e1006678. doi: 10.1371/journal.pgen.1006678. eCollection 2017 Mar. 2017
5RBFOX1
Developmental regulation of RNA processing by Rbfox proteins.
Conboy JG.
Wiley Interdiscip Rev RNA 8(2). doi: 10.1002/wrna.1398. Epub 2016 Oct 17. Review. 2017
6PUM1, RBFOX1
Repression of Pumilio Protein Expression by Rbfox1 Promotes Germ Cell Differentiation.
Carreira-Rosario A, Bhargava V, Hillebrand J, Kollipara RK, Ramaswami M, Buszczak M.
Dev Cell 36(5):562-71. doi: 10.1016/j.devcel.2016.02.010. 2016
7RBFOX1
Cytoplasmic Rbfox1 Regulates the Expression of Synaptic and Autism-Related Genes.
Lee JA, Damianov A, Lin CH, Fontes M, Parikshak NN, Anderson ES, Geschwind DH, Black DL, Martin KC.
Neuron 89(1):113-28. doi: 10.1016/j.neuron.2015.11.025. Epub 2015 Dec 10. 2016
8RBFOX1
RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure.
Gao C, Ren S, Lee JH, Qiu J, Chapski DJ, Rau CD, Zhou Y, Abdellatif M, Nakano A, Vondriska TM, Xiao X, Fu XD, Chen JN, Wang Y.
J Clin Invest 126(1):195-206. doi: 10.1172/JCI84015. Epub 2015 Nov 30. 2016
9RBFOX1
Extending the phenotypic spectrum of RBFOX1 deletions: Sporadic focal epilepsy.
Lal D, Pernhorst K, Klein KM, Reif P, Tozzi R, Toliat MR, Winterer G, Neubauer B, Nürnberg P, Rosenow F, Becker F, Lerche H, Kunz WS, Kurki MI, Hoffmann P, Becker AJ, Perucca E, Zara F, Sander T, Weber YG.
Epilepsia 56(9):e129-33. doi: 10.1111/epi.13076. Epub 2015 Jul 15. 2015
10MEF2D, RBFOX1, RBFOX2
Rbfox proteins regulate tissue-specific alternative splicing of Mef2D required for muscle differentiation.
Runfola V, Sebastian S, Dilworth FJ, Gabellini D.
J Cell Sci 128(4):631-7. doi: 10.1242/jcs.161059. Epub 2015 Jan 20. 2015
11RBFOX1
The RNA-binding protein Rbfox1 regulates splicing required for skeletal muscle structure and function.
Pedrotti S, Giudice J, Dagnino-Acosta A, Knoblauch M, Singh RK, Hanna A, Mo Q, Hicks J, Hamilton S, Cooper TA.
Hum Mol Genet 24(8):2360-74. doi: 10.1093/hmg/ddv003. Epub 2015 Jan 9. 2015
12MBNL1, RBFOX1
RBFOX1 cooperates with MBNL1 to control splicing in muscle, including events altered in myotonic dystrophy type 1.
Klinck R, Fourrier A, Thibault P, Toutant J, Durand M, Lapointe E, Caillet-Boudin ML, Sergeant N, Gourdon G, Meola G, Furling D, Puymirat J, Chabot B.
PLoS One 9(9):e107324. doi: 10.1371/journal.pone.0107324. eCollection 2014. 2014
13RBFOX1
Analysis of RBFOX1 gene expression in lymphoblastoid cell lines of Italian discordant autism spectrum disorders sib-pairs.
Prandini P, Zusi C, Malerba G, Itan, Pignatti PF, Trabetti E.
Mol Cell Probes 28(5-6):242-5. doi: 10.1016/j.mcp.2014.05.001. Epub 2014 Jun 3. 2014
14CAPN3, FRG1, RBFOX1
Rbfox1 downregulation and altered calpain 3 splicing by FRG1 in a mouse model of Facioscapulohumeral muscular dystrophy (FSHD).
Pistoni M, Shiue L, Cline MS, Bortolanza S, Neguembor MV, Xynos A, Ares M Jr, Gabellini D.
PLoS Genet 9(1):e1003186. doi: 10.1371/journal.pgen.1003186. Epub 2013 Jan 3. 2013
15RBFOX1, RBFOX3
RBFOX1 and RBFOX3 mutations in rolandic epilepsy.
Lal D, Reinthaler EM, Altmüller J, Toliat MR, Thiele H, Nürnberg P, Lerche H, Hahn A, Møller RS, Muhle H, Sander T, Zimprich F, Neubauer BA.
PLoS One 8(9):e73323. doi: 10.1371/journal.pone.0073323. eCollection 2013. 2013
16RBFOX1
Orchestration of neurodevelopmental programs by RBFOX1: implications for autism spectrum disorder.
Bill BR, Lowe JK, Dybuncio CT, Fogel BL.
Int Rev Neurobiol 113:251-67. doi: 10.1016/B978-0-12-418700-9.00008-3. Review. 2013
17RBFOX1, RBFOX2
The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function.
Gehman LT, Meera P, Stoilov P, Shiue L, O'Brien JE, Meisler MH, Ares M Jr, Otis TS, Black DL.
Genes Dev 26(5):445-60. doi: 10.1101/gad.182477.111. Epub 2012 Feb 22. 2012
18HNRNPH1, RALY, RBFOX1, RBFOX2, TFG
Mechanisms of activation and repression by the alternative splicing factors RBFOX1/2.
Sun S, Zhang Z, Fregoso O, Krainer AR.
RNA 18(2):274-83. doi: 10.1261/rna.030486.111. Epub 2011 Dec 19. 2012
19RBFOX1, WNK3
Protein kinase WNK3 regulates the neuronal splicing factor Fox-1.
Lee AY, Chen W, Stippec S, Self J, Yang F, Ding X, Chen S, Juang YC, Cobb MH.
Proc Natl Acad Sci U S A 109(42):16841-6. doi: 10.1073/pnas.1215406109. Epub 2012 Oct 1. 2012
20RBFOX1
RBFOX1 regulates both splicing and transcriptional networks in human neuronal development.
Fogel BL, Wexler E, Wahnich A, Friedrich T, Vijayendran C, Gao F, Parikshak N, Konopka G, Geschwind DH.
Hum Mol Genet 21(19):4171-86. doi: 10.1093/hmg/dds240. Epub 2012 Jun 23. 2012
21RBFOX1, RBFOX2, RBFOX3
The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain.
Gehman LT, Stoilov P, Maguire J, Damianov A, Lin CH, Shiue L, Ares M Jr, Mody I, Black DL.
Nat Genet 43(7):706-11. doi: 10.1038/ng.841. 2011
22RBFOX1
An inducible change in Fox-1/A2BP1 splicing modulates the alternative splicing of downstream neuronal target exons.
Lee JA, Tang ZZ, Black DL.
Genes Dev 23(19):2284-93. Epub 2009 Sep 17.PMID: 19762510 2009
23RBFOX1, RBFOX2
Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2.
Zhang C, Zhang Z, Castle J, Sun S, Johnson J, Krainer AR, Zhang MQ.
Genes Dev 22(18):2550-63. doi: 10.1101/gad.1703108. Erratum in: Genes Dev. 2008 Oct 15;22(20):2902. 2008
24RBFOX1, RBFOX2
Repression of prespliceosome complex formation at two distinct steps by Fox-1/Fox-2 proteins.
Zhou HL, Lou H.
Mol Cell Biol 28(17):5507-16. doi: 10.1128/MCB.00530-08. Epub 2008 Jun 23. 2008
25RBFOX1, RBFOX2
Role for Fox-1/Fox-2 in mediating the neuronal pathway of calcitonin/calcitonin gene-related peptide alternative RNA processing.
Zhou HL, Baraniak AP, Lou H.
Mol Cell Biol 27(3):830-41. Epub 2006 Nov 13. 2007
26AGMO, FHIT, RBFOX1, SLC4A10
Strong association of de novo copy number mutations with autism.
Sebat J, Lakshmi B, Malhotra D, Troge J, Lese-Martin C, Walsh T, Yamrom B, Yoon S, Krasnitz A, Kendall J, Leotta A, Pai D, Zhang R, Lee YH, Hicks J, Spence SJ, Lee AT, Puura K, Lehtimaki T, Ledbetter D, Gregersen PK, Bregman J, Sutcliffe JS, Jobanputra V, Chung W, Warburton D, King MC, Skuse D, Geschwind DH, Gilliam TC, Ye K, Wigler M.
Science 316(5823):445-9. Epub 2007 Mar 15. 2007
27AUTS17, RBFOX1
Cytogenetic and molecular characterization of A2BP1/FOX1 as a candidate gene for autism.
Martin CL, Duvall JA, Ilkin Y, Simon JS, Arreaza MG, Wilkes K, Alvarez-Retuerto A, Whichello A, Powell CM, Rao K, Cook E, Geschwind DH.
Am J Med Genet B Neuropsychiatr Genet 144(7):869-76. 2007
28AGPAT6, AGTPBP1, AJUBA, BATF2, BEND2, CCDC107, CELF2, CSTF2, ECM1, EFEMP1, FAM127A, ITGB4, KIF17, LTBP4, NELF, NETS, NPHP1, PCDRS, PEG3, PELI2, PTPRN, PTPRN2, RAD54L2, RBFOX1, RBFOX2, RBPMS, RHOXF1, SCAMP1, SPINK5, TAF9, THAP1, TTC19, UBE2E3, UCHL3, WDYHV1, ZFPM2, ZNF488
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
Lim J, Hao T, Shaw C, Patel AJ, Szabo G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabasi AL, Vidal M, Zoghbi HY.
Cell 125(4):801-14. 2006
29RBFOX1
Molecular basis of RNA recognition by the human alternative splicing factor Fox-1.
Auweter SD, Fasan R, Reymond L, Underwood JG, Black DL, Pitsch S, Allain FH.
EMBO J 25(1):163-73. Epub 2005 Dec 15. 2006
30RBFOX1, RBFOX2
Fox-2 splicing factor binds to a conserved intron motif to promote inclusion of protein 4.1R alternative exon 16.
Ponthier JL, Schluepen C, Chen W, Lersch RA, Gee SL, Hou VC, Lo AJ, Short SA, Chasis JA, Winkelmann JC, Conboy JG.
J Biol Chem 281(18):12468-74. Epub 2006 Mar 14. 2006
31RBFOX1
Identification and expression of a mouse ortholog of A2BP1.
Kiehl TR, Shibata H, Vo T, Huynh DP, Pulst SM.
Mamm Genome 12(8):595-601. 2001
32RBFOX1
A novel protein with RNA-binding motifs interacts with ataxin-2.
Shibata H, Huynh DP, Pulst SM.
Hum Mol Genet 9(9):1303-13. 2000