Citations for
1MAZ, MYB, RB1
MAZ induces MYB expression during the exit from quiescence via the E2F site in the MYB promoter.
Álvaro-Blanco J, Urso K, Chiodo Y, Martín-Cortázar C, Kourani O, Arco PG, Rodríguez-Martínez M, Calonge E, Alcamí J, Redondo JM, Iglesias T, Campanero MR.
Nucleic Acids Res 45(17):9960-9975. doi: 10.1093/nar/gkx641. 2017
2LMNA, RB1, SENP1
SENP1-modulated sumoylation regulates retinoblastoma protein (RB) and Lamin A/C interaction and stabilization.
Sharma P, Kuehn MR.
Oncogene 35(50):6429-6438. doi: 10.1038/onc.2016.177. Epub 2016 Jun 6. 2016
3KDM6B, RB1
JMJD3 promotes SAHF formation in senescent WI38 cells by triggering an interplay between demethylation and phosphorylation of RB protein.
Zhao L, Zhang Y, Gao Y, Geng P, Lu Y, Liu X, Yao R, Hou P, Liu D, Lu J, Huang B.
Cell Death Differ ell Death Differ. 2015 Feb 20. doi: 10.1038/cdd.2015.6. [Epub ahead of print] 2015
4KDM5A, RB1
Increased mitochondrial function downstream from KDM5A histone demethylase rescues differentiation in pRB-deficient cells.
Váraljai R, Islam AB, Beshiri ML, Rehman J, Lopez-Bigas N, Benevolenskaya EV.
Genes Dev 29(17):1817-34. doi: 10.1101/gad.264036.115. Epub 2015 Aug 27. 2015
5DNMT1, RB1
RB maintains quiescence and prevents premature senescence through upregulation of DNMT1 in mesenchymal stromal cells.
Lin SP, Chiu FY, Wang Y, Yen ML, Kao SY, Hung SC.
Stem Cell Reports 3(6):975-86. doi: 10.1016/j.stemcr.2014.10.002. Epub 2014 Nov 6. 2014
6CDKN1B, CDKN2B, RB1, SMAD2
Smad2 overexpression reduces the proliferation of the junctional epithelium.
Alotaibi MK, Kitase Y, Shuler CF.
J Dent Res 93(9):898-903. doi: 10.1177/0022034514543016. Epub 2014 Jul 14. 2014
7RB, RB1
Fine mapping of whole RB1 gene deletions in retinoblastoma patients confirms PCDH8 as a candidate gene for psychomotor delay.
Castéra L, Dehainault C, Michaux D, Lumbroso-Le Rouic L, Aerts I, Doz F, Pelet A, Couturier J, Stoppa-Lyonnet D, Gauthier-Villars M, Houdayer C.
Eur J Hum Genet 21(4):460-4. doi: 10.1038/ejhg.2012.186. Epub 2012 Aug 22. 2013
8RB1, RBL1
Loss of pRB and p107 disrupts cartilage development and promotes enchondroma formation.
Landman AS, Danielian PS, Lees JA.
Oncogene 32(40):4798-805. doi: 10.1038/onc.2012.496. Epub 2012 Nov 12. 2013
9CIC, RB1
Capicua regulates proliferation and survival of RB-deficient cells in Drosophila.
Krivy K, Bradley-Gill MR, Moon NS.
Biol Open 2(2):183-90. doi: 10.1242/bio.20123277. Epub 2012 Nov 23. 2013
10NOL7, RB1
The RB tumor suppressor positively regulates transcription of the anti-angiogenic protein NOL7.
Mankame TP, Lingen MW.
Neoplasia 14(12):1213-22. 2012
11RB1, SMYD2
RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation.
Cho HS, Hayami S, Toyokawa G, Maejima K, Yamane Y, Suzuki T, Dohmae N, Kogure M, Kang D, Neal DE, Ponder BA, Yamaue H, Nakamura Y, Hamamoto R.
Neoplasia 14(6):476-86. 2012
12RB1
Retinal horizontal cells lacking Rb1 sustain persistent DNA damage and survive as polyploid giant cells.
Donovan SL, Corbo JC.
Mol Biol Cell 23(22):4362-72. doi: 10.1091/mbc.E12-04-0293. Epub 2012 Sep 26. 2012
13PDX1, RB1
RB regulates pancreas development by stabilizing Pdx1.
Kim YC, Kim SY, Mellado-Gil JM, Yadav H, Neidermyer W, Kamaraju AK, Rane SG.
EMBO J 30(8):1563-76. Epub 2011 Mar 11. 2011
14RB1, RBP2
Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1.
Lin W, Cao J, Liu J, Beshiri ML, Fujiwara Y, Francis J, Cherniack AD, Geisen C, Blair LP, Zou MR, Shen X, Kawamori D, Liu Z, Grisanzio C, Watanabe H, Minamishima YA, Zhang Q, Kulkarni RN, Signoretti S, Rodig SJ, Bronson RT, Orkin SH, Tuck DP, Benevolenskaya EV, Meyerson M, Kaelin WG Jr, Yan Q.
Proc Natl Acad Sci U S A 108(33):13379-86. Epub 2011 Jul 25. 2011
15RB1, RBP1, SAP30
Cyclin-dependent kinase-mediated phosphorylation of RBP1 and pRb promotes their dissociation to mediate release of the SAP30ˇmSin3ˇHDAC transcriptional repressor complex.
Suryadinata R, Sadowski M, Steel R, Sarcevic B.
J Biol Chem 286(7):5108-18. Epub 2010 Dec 9. 2011
16DEL13Q14, RB, RB1
Genotype-phenotype correlations in patients with retinoblastoma and interstitial 13q deletions.
Mitter D, Ullmann R, Muradyan A, Klein-Hitpass L, Kanber D, Ounap K, Kaulisch M, Lohmann D.
Eur J Hum Genet 19(9):947-58. doi: 10.1038/ejhg.2011.58. Epub 2011 Apr 20. 2011
17RB1, RBL1, RBL2
Critical role of the Rb family in myoblast survival and fusion.
Ciavarra G, Ho AT, Cobrinik D, Zacksenhaus E.
PLoS One 6(3):e17682. doi: 10.1371/journal.pone.0017682. 2011
18E2F4, RB1, RBL1, RBL2
Regulation of RB transcription in vivo by RB family members.
Burkhart DL, Ngai LK, Roake CM, Viatour P, Thangavel C, Ho VM, Knudsen ES, Sage J.
Mol Cell Biol 30(7):1729-45. Epub 2010 Jan 25. 2010
19CDK5, CDK5R1, RB1
p35 is required for CDK5 activation in cellular senescence.
Mao D, Hinds PW.
J Biol Chem 285(19):14671-80. Epub 2010 Feb 24.PMID: 20181942 2010
20KDM6A, RB1, RBL2
The tumor suppressor Rb and its related Rbl2 genes are regulated by Utx histone demethylase.
Terashima M, Ishimura A, Yoshida M, Suzuki Y, Sugano S, Suzuki T.
Biochem Biophys Res Commun 399(2):238-44. Epub 2010 Jul 30.PMID: 20650264 2010
21RB1
An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein.
Hirschi A, Cecchini M, Steinhardt RC, Schamber MR, Dick FA, Rubin SM.
Nat Struct Mol Biol 17(9):1051-7. Epub 2010 Aug 8.PMID: 20694007 2010
22RB1
Rb regulates fate choice and lineage commitment in vivo.
Calo E, Quintero-Estades JA, Danielian PS, Nedelcu S, Berman SD, Lees JA.
Nature 466(7310):1110-4. Epub 2010 Aug 4.PMID: 20686481 2010
23RB1
E2F-1 binding affinity for pRb is not the only determinant of the E2F-1 activity.
Sahin F, Sladek TL.
Int J Biol Sci 6(4):382-95.PMID: 20616879 2010
24RB1
Mitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressive.
Coschi CH, Martens AL, Ritchie K, Francis SM, Chakrabarti S, Berube NG, Dick FA.
Genes Dev 24(13):1351-63. Epub 2010 Jun 15.PMID: 20551166 2010
25RB1
Loss of pRB causes centromere dysfunction and chromosomal instability.
Manning AL, Longworth MS, Dyson NJ.
Genes Dev 24(13):1364-76. Epub 2010 Jun 15.PMID: 20551165 2010
26RB1
Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling.
van Harn T, Foijer F, van Vugt M, Banerjee R, Yang F, Oostra A, Joenje H, te Riele H.
Genes Dev. 24(13):1377-88 2010
27CTBP1, E2F1, RB1, RBBP8, TRIM28, ZNF350
RBˇE2F1 complex mediates DNA damage responses through transcriptional regulation of ZBRK1.
Liao CC, Tsai CY, Chang WC, Lee WH, Wang JM.
J Biol Chem 285(43):33134-43. Epub 2010 Aug 16. 2010
28L3MBTL1, RB1, SMYD2
Methylation of the retinoblastoma tumor suppressor by SMYD2.
Saddic LA, West LE, Aslanian A, Yates JR 3rd, Rubin SM, Gozani O, Sage J.
J Biol Chem 285(48):37733-40. Epub 2010 Sep 24. 2010
29E2F4, RB1
pRB and E2F4 play distinct cell-intrinsic roles in fetal erythropoiesis.
Zhang J, Lee EY, Liu Y, Berman SD, Lodish HF, Lees JA.
Cell Cycle 9(2):371-6. Epub 2010 Jan 29. 2010
30RB1, RBL1, RBL2
Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects.
Berman SD, West JC, Danielian PS, Caron AM, Stone JR, Lees JA.
Proc Natl Acad Sci U S A 106(35):14932-6. Epub 2009 Aug 19.PMID: 19706423 2009
31RB1, RB1CC1
RB1CC1 activates the promoter and expression of RB1 in human cancer.
Ikebuchi K, Chano T, Ochi Y, Tameno H, Shimada T, Hisa Y, Okabe H.
Int J Cancer 125(4):861-7.PMID: 19437535 2009
32RB1
Aurora B kinase regulates the postmitotic endoreduplication checkpoint via phosphorylation of the retinoblastoma protein at serine 780.
Nair JS, Ho AL, Tse AN, Coward J, Cheema H, Ambrosini G, Keen N, Schwartz GK.
Mol Biol Cell. 20(8):2218-28. 2009
33RB, RB1
Loss of RB1 induces non-proliferative retinoma: increasing genomic instability correlates with progression to retinoblastoma.
Dimaras H, Khetan V, Halliday W, Orlic M, Prigoda NL, Piovesan B, Marrano P, Corson TW, Eagle RC Jr, Squire JA, Gallie BL.
Hum Mol Genet 17(10):1363-72. Epub 2008 Jan 22. 2008
34APC, BRCA1, BRCA2, CDH1, CDKN2A, MLH1, MSH2, MSH6, PMS2, PRSS1, PTEN, RB1, SPINK1, STK11, TP53
Inherited susceptibility to common cancers.
Foulkes WD.
N Engl J Med 359(20):2143-53. No abstract available. 2008
35RB1, ZBTB7A
Proto-oncogene FBI-1 (Pokemon/ZBTB7A) represses transcription of the tumor suppressor Rb gene via binding competition with Sp1 and recruitment of co-repressors.
Jeon BN, Yoo JY, Choi WI, Lee CE, Yoon HG, Hur MW.
J Biol Chem 283(48):33199-210. Epub 2008 Sep 18. 2008
36RB, RB1
Retinoblastoma: what is new in 2007-2008.
Schefler AC, Abramson DH.
Curr Opin Ophthalmol 19(6):526-34. Review. 2008
37RB1, ZBTB16
Retinoblastoma protein and the leukemia-associated PLZF transcription factor interact to repress target gene promoters.
Petrie K, Guidez F, Zhu J, Howell L, Owen G, Chew YP, Parks S, Waxman S, Licht J, Mittnacht S, Zelent A.
Oncogene 27(39):5260-6. Epub 2008 May 26. 2008
38RB1, RB
Genotype-phenotype correlations in hereditary familial retinoblastoma.
Taylor M, Dehainault C, Desjardins L, Doz F, Levy C, Sastre X, Couturier J, Stoppa-Lyonnet D, Houdayer C, Gauthier-Villars M.
Hum Mutat 28(3):284-93. 2007
39RB1
A deep intronic mutation in the RB1 gene leads to intronic sequence exonisation.
Dehainault C, Michaux D, Pages-Berhouet S, Caux-Moncoutier V, Doz F, Desjardins L, Couturier J, Parent P, Stoppa-Lyonnet D, Gauthier-Villars M, Houdayer C.
Eur J Hum Genet 15(4):473-7. Epub 2007 Feb 14. 2007
40RB1
Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit.
Binné UK, Classon MK, Dick FA, Wei W, Rape M, Kaelin WG Jr, Näär AM, Dyson NJ.
Nat Cell Biol. 9(2):225-32. 2007
41RB1
ATM regulates ionizing radiation-induced disruption of HDAC1:PP1:Rb complexes.
Guo C, Mi J, Brautigan DL, Larner JM.
Cell Signal. 19(3):504-10. 2007
42RB1
Common variants in RB1 gene and risk of invasive ovarian cancer.
Song H, Ramus SJ, Shadforth D, Quaye L, Kjaer SK, Dicioccio RA, Dunning AM, Hogdall E, Hogdall C, Whittemore AS, McGuire V, Lesueur F, Easton DF, Jacobs IJ, Ponder BA, Gayther SA, Pharoah PD.
Cancer Res 66(20):10220-6. 2006
43MDM4, RB1, TP53
Inactivation of the p53 pathway in retinoblastoma.
Laurie NA, Donovan SL, Shih CS, Zhang J, Mills N, Fuller C, Teunisse A, Lam S, Ramos Y, Mohan A, Johnson D, Wilson M, Rodriguez-Galindo C, Quarto M, Francoz S, Mendrysa SM, Guy RK, Marine JC, Jochemsen AG, Dyer MA.
Nature 444(7115):61-6. 2006
44CDKN1A, CDKN1B, CDKN2A, RB1
Age differences in cyclin-dependent kinase inhibitor expression and rb hyperphosphorylation in human corneal endothelial cells.
Enomoto K, Mimura T, Harris DL, Joyce NC.
Invest Ophthalmol Vis Sci 47(10):4330-40. 2006
45RB1
RB, the conductor that orchestrates life, death and differentiation.
Khidr L, Chen PL.
Oncogene 25(38):5210-9. Review. 2006
46RB1, BCR, ABL1
Rb plays a role in survival of Abl-dependent human tumor cells as a downstream effector of Abl tyrosine kinase.
Nagano K, Itagaki C, Izumi T, Nunomura K, Soda Y, Tani K, Takahashi N, Takenawa T, Isobe T.
Oncogene 25(4):493-502. 2006
47DGKZ, RB1, RBL1, RBL2
The retinoblastoma family proteins bind to and activate diacylglycerol kinase zeta.
Los AP, Vinke FP, de Widt J, Topham MK, van Blitterswijk WJ, Divecha N.
J Biol Chem 281(2):858-66. Epub 2005 Nov 14.PMID: 16286473 2006
48RB1
p205, a potential tumor suppressor, inhibits cell proliferation via multiple pathways of cell cycle regulation.
Asefa B, Dermott JM, Kaldis P, Stefanisko K, Garfinkel DJ, Keller JR.
FEBS Lett. 580(5):1205-14. 2006
49RB1
HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity.
Fedele M, Visone R, De Martino I, Troncone G, Palmieri D, Battista S, Ciarmiello A, Pallante P, Arra C, Melillo RM, Helin K, Croce CM, Fusco A.
Cancer Cell. 9(6):459-71. 2006
50RB1
Essential role of retinoblastoma protein in mammalian hair cell development and hearing.
Sage C, Huang M, Vollrath MA, Brown MC, Hinds PW, Corey DP, Vetter DE, Chen ZY.
Proc Natl Acad Sci U S A. 103(19):7345-50. 2006
51RB1
Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein.
Sage C, Huang M, Karimi K, Gutierrez G, Vollrath MA, Zhang DS, Garcia-Anoveros J, Hinds PW, Corwin JT, Corey DP, Chen ZY.
Science 307(5712):1114-8. Epub 2005 Jan 13. 2005
52RB1
Binding of pRB to the PHD protein RBP2 promotes cellular differentiation.
Benevolenskaya EV, Murray HL, Branton P, Young RA, Kaelin WG Jr.
Mol Cell. 18(6):623-35. 2005
53RB1
Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression.
Carreira S, Goodall J, Aksan I, La Rocca SA, Galibert MD, Denat L, Larue L, Goding CR.
Nature. 433(7027):764-9. 2005
54HIF1A, RB1
Retinoblastoma susceptibility gene product pRB activates hypoxia-inducible factor-1 (HIF-1).
Budde A, Schneiderhan-Marra N, Petersen G, Brüne B.
Oncogene. 24(10):1802-8. 2005
55RB1
Viral oncoproteins E1A and E7 and cellular LxCxE proteins repress SUMO modification of the retinoblastoma tumor suppressor.
Ledl A, Schmidt D, Müller S.
Oncogene. 24(23):3810-8. 2005
56RB1
Retinoblastoma-binding protein 2-homolog 1: a retinoblastoma-binding protein downregulated in malignant melanomas.
Roesch A, Becker B, Meyer S, Wild P, Hafner C, Landthaler M, Vogt T.
Mod Pathol. 18(9):1249-57. 2005
57RB1
Selective ablation of retinoblastoma protein function by the RET finger protein.
Krützfeldt M, Ellis M, Weekes DB, Bull JJ, Eilers M, Vivanco MD, Sellers WR, Mittnacht S.
Mol Cell. 18(2):213-24. 2005
58RB1, SMARCA4, CDKN1A
BRG1 controls the activity of the retinoblastoma protein via regulation of p21CIP1/WAF1/SDI.
Kang H, Cui K, Zhao K.
Mol Cell Biol 24(3):1188-99. 2004
59LIN9, RB1
Inhibition of oncogenic transformation by mammalian Lin-9, a pRB-associated protein.
Gagrica S, Hauser S, Kolfschoten I, Osterloh L, Agami R, Gaubatz S.
EMBO J 23(23):4627-38. Epub 2004 Nov 11. 2004
60CEBPE, RB1, SGD
C/EBPepsilon interacts with retinoblastoma and E2F1 during granulopoiesis.
Gery S, Gombart AF, Fung YK, Koeffler HP.
Blood 103(3):828-35. Epub 2003 Aug 28. 2004
61RB, DEL13Q14, RB1
Retinoblastoma: revisiting the model prototype of inherited cancer.
Lohmann DR, Gallie BL.
Am J Med Genet C Semin Med Genet 129(1):23-8. Review. 2004
62RB1
An Rb-Skp2-p27 pathway mediates acute cell cycle inhibition by Rb and is retained in a partial-penetrance Rb mutant.
Ji P, Jiang H, Rekhtman K, Bloom J, Ichetovkin M, Pagano M, Zhu L.
Mol Cell. 16(1):47-58. 2004
63RB1
Acetylation regulates the differentiation-specific functions of the retinoblastoma protein.
Nguyen DX, Baglia LA, Huang SM, Baker CM, McCance DJ.
EMBO J. 23(7):1609-18. 2004
64RB1
Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma.
Thomas DM, Johnson SA, Sims NA, Trivett MK, Slavin JL, Rubin BP, Waring P, McArthur GA, Walkley CR, Holloway AJ, Diyagama D, Grim JE, Clurman BE, Bowtell DD, Lee JS, Gutierrez GM, Piscopo DM, Carty SA, Hinds PW.
J Cell Biol. 167(5):925-34. 2004
65RB1
Interactions between activating signal cointegrator-2 and the tumor suppressor retinoblastoma in androgen receptor transactivation.
Goo YH, Na SY, Zhang H, Xu J, Hong S, Cheong J, Lee SK, Lee JW.
J Biol Chem. 279(8):7131-5 2004
66RB1
Interaction of FIE, a polycomb protein, with pRb: a possible mechanism regulating endosperm development.
Mosquna A, Katz A, Shochat S, Grafi G, Ohad N.
Mol Genet Genomics. 271(6):651-7. 2004
67RACK1, RB1
Function of p73, not of p53, is inhibited by the physical interaction with RACK1 and its inhibitory effect is counteracted by pRB.
Ozaki T, Watanabe K, Nakagawa T, Miyazaki K, Takahashi M, Nakagawara A.
Oncogene. 22(21):3231-42. 2003
68RB1
Inhibition of retinoblastoma protein degradation by interaction with the serpin plasminogen activator inhibitor 2 via a novel consensus motif.
Darnell GA, Antalis TM, Johnstone RW, Stringer BW, Ogbourne SM, Harrich D, Suhrbier A.
Mol Cell Biol. 23(18):6520-32. 2003
69RB1
Functional interactions between the estrogen receptor coactivator PELP1/MNAR and retinoblastoma protein.
Balasenthil S, Vadlamudi RK.
J Biol Chem. 278(24):22119-27. 2003
70RB1
The retinoblastoma protein interacts with Bag-1 in human colonic adenoma and carcinoma derived cell lines.
Arhel NJ, Packham G, Townsend PA, Collard TJ, H-Zadeh AM, Sharp A, Cutress RI, Malik K, Hague A, Paraskeva C, Williams AC.
Int J Cancer. 106(3):364-71. 2003
71RB1
Tumor suppressor pRB functions as a co-repressor of the CCAAT displacement protein (CDP/cut) to regulate cell cycle controlled histone H4 transcription.
Gupta S, Luong MX, Bleuming SA, Miele A, Luong M, Young D, Knudsen ES, Van Wijnen AJ, Stein JL, Stein GS.
J Cell Physiol. 196(3):541-56. 2003
72RB1
Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system.
MacPherson D, Sage J, Crowley D, Trumpp A, Bronson RT, Jacks T.
Mol Cell Biol. 23(3):1044-53. 2003
73CDKN2A, DLC1, EXT1, MLH1, PTEN, RB1, TP53, TP73
Molecular pathogenesis of human hepatocellular carcinoma.
Thorgeirsson SS, Grisham JW.
Nat Genet 31(4):339-46. 2002
74BCL2, CDKN2A, MYC, RB1, TSG3B
Cytogenetics and molecular genetics of lung cancer.
Mitsuuchi Y, Testa JR.
Am J Med Genet 115(3):183-8. 2002
75LMNA, RB1, TMPO
Lamin A/C binding protein LAP2alpha is required for nuclear anchorage of retinoblastoma protein.
Markiewicz E, Dechat T, Foisner R, Quinlan RA, Hutchison CJ.
Mol Biol Cell 13(12):4401-13. 2002
76DNMT1, RB1
The retinoblastoma gene product interacts with maintenance human DNA (cytosine-5) methyltransferase and modulates its activity.
Pradhan S, Kim GD.
EMBO J. 21(4):779-88. 2002
77RB1
Interaction of the retinoblastoma gene product, RB, with cyclophilin A negatively affects cyclosporin-inhibited NFAT signaling.
Cui Y, Mirkia K, Florence Fu YH, Zhu L, Yokoyama KK, Chiu R.
J Cell Biochem. 86(4):630-41. 2002
78RB1
Physical interaction between pRb and cdk9/cyclinT2 complex.
Simone C, Bagella L, Bellan C, Giordano A.
Oncogene. 21(26):4158-65. 2002
79RB1
Pax-2 interacts with RB and reverses its repression on the promoter of Rig-1, a Robo member.
Yuan SS, Yeh YT, Lee EY.
Biochem Biophys Res Commun. 296(4):1019-25. 2002
80RB1
MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation.
Pardo PS, Leung JK, Lucchesi JC, Pereira-Smith OM.
J Biol Chem. 277(52):50860-6. 2002
81RB1
Characterization of protein kinase C beta isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularization.
Suzuma K, Takahara N, Suzuma I, Isshiki K, Ueki K, Leitges M, Aiello LP, King GL.
Proc Natl Acad Sci U S A. 99(2):721-6. 2002
82RB1
Skip interacts with the retinoblastoma tumor suppressor and inhibits its transcriptional repression activity.
Prathapam T, Kühne C, Banks L.
Nucleic Acids Res. 30(23):5261-8. 2002
83RB,RB1
Spectrum of germline RB1 gene mutations in Spanish retinoblastoma patients: Phenotypic and molecular epidemiological implications.
Alonso J, Garcia-Miguel P, Abelairas J, Mendiola M, Sarret E, Vendrell MT, Navajas A, Pestana A.
Hum Mutat 17(5):412-22. 2001
84E2F1,RB,RB1
The Rb/E2F pathway and cancer.
Nevins JR.
Hum Mol Genet 10(7):699-703. Review. 2001
85BCL2, CCNA1, CCNB1, CCND1, CDKN1A, CDKN2A, MKI67, RB1
Immunohistochemical expression of p53, p21/waf1, rb, p16, cyclin D1, p27, Ki67, cyclin A, cyclin B1, bcl2, bax and bak proteins and apoptotic index in normal thymus.
Kanavaros P, Stefanaki K, Rontogianni D, Papalazarou D, Sgantzos M, Arvanitis D, Vamvouka C, Gorgoulis V, Siatitsas I, Agnantis NJ, Bai M.
Histol Histopathol 16(4):1005-12. 2001
86RB1
Retinoblastoma protein interacts with ATF2 and JNK/p38 in stimulating the transforming growth factor-beta2 promoter.
Li H, Wicks WD.
Arch Biochem Biophys. 394(1):1-12. 2001
87RB1
Sequential two-step cleavage of the retinoblastoma protein by caspase-3/-7 during etoposide-induced apoptosis.
Fattman CL, Delach SM, Dou QP, Johnson DE.
Oncogene. 20(23):2918-26. 2001
88RB1
Maximal aryl hydrocarbon receptor activity depends on an interaction with the retinoblastoma protein.
Elferink CJ, Ge NL, Levine A.
Mol Pharmacol. 59(4):664-73. 2001
89RB1
Cutting edge: differential signaling requirements for activation of assembled cyclin D3-cdk4 complexes in B-1 and B-2 lymphocyte subsets.
Tanguay DA, Colarusso TP, Doughty C, Pavlovic-Ewers S, Rothstein TL, Chiles TC.
J Immunol. 166(7):4273-7. 2001
90RB1
Ebp1, an ErbB-3 binding protein, interacts with Rb and affects Rb transcriptional regulation.
Xia X, Cheng A, Lessor T, Zhang Y, Hamburger AW.
J Cell Physiol. 187(2):209-17. 2001
91RB1
Rb targets histone H3 methylation and HP1 to promoters.
Nielsen SJ, Schneider R, Bauer UM, Bannister AJ, Morrison A, O'Carroll D, Firestein R, Cleary M, Jenuwein T, Herrera RE, Kouzarides T.
Nature. 412(6846):561-5. 2001
92RB1
The de-ubiquitinating enzyme Unp interacts with the retinoblastoma protein.
DeSalle LM, Latres E, Lin D, Graner E, Montagnoli A, Baker RT, Pagano M, Loda M.
Oncogene. 20(39):5538-42. 2001
93RB1
The RB1 gene is the target of chromosome 13 deletions in malignant fibrous histiocytoma.
Chibon F, Mairal A, Freneaux P, Terrier P, Coindre JM, Sastre X, Aurias A.
Cancer Res 60(22):6339-45. 2000
94RB1
Loss of heterozygosity at 13q14 correlates with RB1 gene underexpression in human breast cancer.
Bieche I, Lidereau R.
Mol Carcinog 29(3):151-8. 2000
95CDKN2A, RB1
Frequent alterations in the expression of tumor suppressor genes p16INK4A and pRb in esophageal squamous cell carcinoma in the Indian population.
Ralhan R, Mathew R, Arora S, Bahl R, Shukla NK, Mathur M.
J Cancer Res Clin Oncol 126(11):655-60. 2000
96RB1, RBAK
Cloning and characterization of a novel Kruppel-associated box family transcriptional repressor that interacts with the retinoblastoma gene product, RB.
Skapek SX, Jansen D, Wei TF, McDermott T, Huang W, Olson EN, Lee EY.
J Biol Chem 275(10):7212-23. 2000
97RB1
Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb.
Fanciulli M, Bruno T, Di Padova M, De Angelis R, Iezzi S, Iacobini C, Floridi A, Passananti C.
FASEB J. 14(7):904-12. 2000
98RB1
Cyclin D1 suppresses retinoblastoma protein-mediated inhibition of TAFII250 kinase activity.
Siegert JL, Rushton JJ, Sellers WR, Kaelin WG Jr, Robbins PD.
Oncogene. 19(50):5703-11. 2000
99RB1
The retinoblastoma tumor suppressor protein targets distinct general transcription factors to regulate RNA polymerase III gene expression.
Hirsch HA, Gu L, Henry RW.
Mol Cell Biol. 20(24):9182-91. 2000
100RB1
pRB binds to and modulates the transrepressing activity of the E1A-regulated transcription factor p120E4F.
Fajas L, Paul C, Zugasti O, Le Cam L, Polanowska J, Fabbrizio E, Medema R, Vignais ML, Sardet C.
Proc Natl Acad Sci U S A. 97(14):7738-43. 2000
101RB1
A novel Rb- and p300-binding protein inhibits transactivation by MyoD.
MacLellan WR, Xiao G, Abdellatif M, Schneider MD.
Mol Cell Biol. 20(23):8903-15. 2000
102RB1
Nuclear colocalization and complex formation of insulin with retinoblastoma protein in HepG2 human hepatoma cells.
Radulescu RT, Doklea ED, Kehe K, Mückter H.
J Endocrinol. 166(2):R1-4. 2000
103RB1
Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas.
Higashitsuji H, Itoh K, Nagao T, Dawson S, Nonoguchi K, Kido T, Mayer RJ, Arii S, Fujita J.
Nat Med. 6(1):96-9. 2000
104RB1
Rb and p130 regulate RNA polymerase I transcription: Rb disrupts the interaction between UBF and SL-1.
Hannan KM, Hannan RD, Smith SD, Jefferson LS, Lun M, Rothblum LI.
Oncogene. 19(43):4988-99. 2000
105RB,RB1,TSG13A
Mitotic recombination map of 13cen-13q14 derived from an investigation of loss of heterozygosity in retinoblastomas.
Hagstrom SA, et al.
Proc Natl Acad Sci U S A 96(6):2952-2957. 1999
106RB1, CDKN2A
Level of retinoblastoma protein expression correlates with p16 (MTS-1/INK4A/CDKN2) status in bladder cancer.
Benedict WF, et al.
Oncogene 18(5):1197-203. 1999
107CCND1, RB1
Expression of PRAD1/cyclin D1, retinoblastoma gene products, and Ki67 in parathyroid hyperplasia caused by chronic renal failure versus primary adenoma.
Tominaga Y, et al.
Kidney Int 55(4):1375-83. 1999
108RB1, TSG13B
Chromosome 13q deletion mapping in pituitary tumors: infrequent loss of the retinoblastoma susceptibility gene (RB1) locus despite loss of RB1 protein product in somatotrophinomas.
Simpson DJ, et al.
Cancer Res 59(7):1562-6. 1999
109TOP2A, RB1
Functional interaction between human topoisomerase IIalpha and retinoblastoma protein.
Bhat UG, et al.
Proc Natl Acad Sci U S A 96(14):7859-64. 1999
110DEL13Q14,RB,RB1
Dysmorphic phenotype and neurological impairment in 22 retinoblastoma patients with constitutional cytogenetic 13q deletion.
Baud O, et al.
Clin Genet 55(6):478-82. 1999
111E2F1, PHB, RB1
Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function.
Wang S, Nath N, Adlam M, Chellappan S.
Oncogene 18(23):3501-10. 1999
112BRCA1, RB1
BRCA1-associated growth arrest is RB-dependent.
Aprelikova ON, et al.
Proc Natl Acad Sci U S A 96(21):11866-71 1999
113RB,RB1
RB1 gene mutations in retinoblastoma.
Lohmann DR.
Hum Mutat 14(4):283-288 1999
114RB,RB1
Temperature-Sensitive RB Mutations Linked to Incomplete Penetrance of Familial Retinoblastoma in 12 Families.
Otterson GA, et al.
Am J Hum Genet 65(4):1040-1046 1999
115ARID3B, RB1
Bdp, a new member of a family of DNA-binding proteins, associates with the retinoblastoma gene product.
Numata S, Claudio PP, Dean C, Giordano A, Croce CM.
Cancer Res 59(15):3741-7. 1999
116RB1
The partial homeodomain of the transcription factor Pax-5 (BSAP) is an interaction motif for the retinoblastoma and TATA-binding proteins.
Eberhard D, Busslinger M.
Cancer Res. 59(7 Suppl):1716s-1724s 1999
117JUN, RB1
Recruitment of the retinoblastoma protein to c-Jun enhances transcription activity mediated through the AP-1 binding site.
Nishitani J, Nishinaka T, Cheng CH, Rong W, Yokoyama KK, Chiu R.
J Biol Chem. 274(9):5454-61. 1999
118RB1
Direct interaction of p21 cyclin-dependent kinase inhibitor with the retinoblastoma tumor suppressor protein.
Nakanishi M, Kaneko Y, Matsushime H, Ikeda K.
Biochem Biophys Res Commun. 263(1):35-40. 1999
119RB1
Functions of cyclin A1 in the cell cycle and its interactions with transcription factor E2F-1 and the Rb family of proteins.
Yang R, Müller C, Huynh V, Fung YK, Yee AS, Koeffler HP.
Mol Cell Biol. 19(3):2400-7. 1999
120PAX3, PAX6, RB1
Pax-6 interactions with TATA-box-binding protein and retinoblastoma protein.
Cvekl A, Kashanchi F, Brady JN, Piatigorsky J.
Invest Ophthalmol Vis Sci. 40(7):1343-50. 1999
121RB1
Rb interacts with histone deacetylase to repress transcription.
Luo RX, Postigo AA, Dean DC.
Cell 92(4):463-73. 1998
122RB,RB1
Frequency of somatic and germ-line mosaicism in retinoblastoma : implications for genetic counseling.
Sippel KC, et al.
Am J Hum Genet 62 : 610-619. 1998
123RB,RB1
A novel missense mutation in patients from a retinoblastoma pedigree showing only mild expression of the tumor phenotype.
Cowell JK, et al.
Oncogene 16 : 3211-3213. 1998
124RB1, RBBP8
Molecular cloning and characterization of a novel retinoblastoma-binding protein.
Fusco C, et al.
Genomics 51 : 351-358. 1998
125HDAC1, RB1
Retinoblastoma protein recruits histone deacetylase to repress transcription.
Brehm A, et al.
Nature 391 : 597-601. 1998
126APC, BRCA1, DPP4, MLH1, MSH2, MSH6, NF1, PMS2, RB1, TP53, VHL, WT1, FAP
Tumour suppressor gene mutations in humans and mice : parallels and contrasts.
Hooper ML.
EMBO J 17(23):6783-9. 1998
127RB,RB1
Evidence of somatic and germinal mosaicism in pseudo-low-penetrant hereditary retinoblastoma, by constitutional and single-sperm mutation analysis.
Munier FL, et al.
Am J Hum Genet 63 : 1903-1908. 1998
128AHR, RB1
A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle.
Ge NL, Elferink CJ.
J Biol Chem 273(35):22708-13. 1998
129RB1, TGFB1, RBBP9
A retinoblastoma-binding protein that affects cell-cycle control and confers transforming ability.
Woitach JT, Zhang M, Niu CH, Thorgeirsson SS.
Nat Genet 19(4):371-4. 1998
130RB1
Retinoblastoma, a tumor suppressor, is a coactivator for the androgen receptor in human prostate cancer DU145 cells.
Yeh S, Miyamoto H, Nishimura K, Kang H, Ludlow J, Hsiao P, Wang C, Su C, Chang C.
Biochem Biophys Res Commun. 248(2):361-7. 1998
131RB1
Raf-1 physically interacts with Rb and regulates its function: a link between mitogenic signaling and cell cycle regulation.
Wang S, Ghosh RN, Chellappan SP.
Mol Cell Biol. 18(12):7487-98. 1998
132RB1
Negative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7.
Sterner JM, Dew-Knight S, Musahl C, Kornbluth S, Horowitz JM.
Mol Cell Biol. 18(5):2748-57. 1998
133RB,RB1
Constitutively methylated CpG dinucleotides as mutation hot spots in the retinoblastoma gene (RB1).
Mancini D, Singh S, Ainsworth P, Rodenhiser D.
Am J Hum Genet 61(1):80-7. 1997
134RB,RB1
Constitutional RB1-gene mutations in patients with isolated unilateral retinoblastoma.
Lohmann DR, Gerick M, Brandt B, Oelschlager U, Lorenz B, Passarge E, Horsthemke B.
Am J Hum Genet 61(2):282-94. 1997
135BCLL1,RB,RB1,TSG13B
Cytogenetic, fluorescence in situ hybridisation, and clinical evaluation of translocations with concomitant deletion at 13q14 in chronic lymphocytic leukaemia.
Gardiner AC, Corcoran MM, Oscier DG.
Genes Chromosomes Cancer 20(1):73-81. 1997
136RB,RB1
A splicing mutation in RB1 in low penetrance retinoblastoma.
Schubert EL, Strong LC, Hansen MF.
Hum Genet 100(5-6):557-63. 1997
137RB,RB1
Deletion of RB exons 24 and 25 causes low-penetrance retinoblastoma.
Bremner R, Du DC, Connolly-Wilson MJ, Bridge P, Ahmad KF, Mostachfi H, Rushlow D, Dunn JM, Gallie BL.
Am J Hum Genet 61(3):556-70. 1997
138RB,RB1
Incomplete penetrance of familial retinoblastoma linked to germ-line mutations that result in partial loss of RB function.
Otterson GA, et al.
Proc Natl Acad Sci U S A 94 : 12036-12040. 1997
139AMLT5, RB1, TRIP11
A thyroid hormone receptor coactivator negatively regulated by the retinoblastoma protein.
Chang KH, et al.
Proc Natl Acad Sci U S A 94(17):9040-5 1997
140RB1
RNA polymerase III transcription repressed by Rb through its interactions with TFIIIB and TFIIIC2.
Chu WM, Wang Z, Roeder RG, Schmid CW.
J Biol Chem. 272(23):14755-61. 1997
141RB1
Identification of domains within the human cytomegalovirus major immediate-early 86-kilodalton protein and the retinoblastoma protein required for physical and functional interaction with each other.
Fortunato EA, Sommer MH, Yoder K, Spector DH.
J Virol. 71(11):8176-85. 1997
142RB1
The HMG-box transcription factor HBP1 is targeted by the pocket proteins and E1A.
Lavender P, Vandel L, Bannister AJ, Kouzarides T.
Oncogene. 14(22):2721-8. 1997
143RB1
Phosphorylated retinoblastoma protein stimulates DNA polymerase alpha.
Takemura M, Kitagawa T, Izuta S, Wasa J, Takai A, Akiyama T, Yoshida S.
Oncogene. 15(20):2483-92. 1997
144RB1
PACT: cloning and characterization of a cellular p53 binding protein that interacts with Rb.
Simons A, Melamed-Bessudo C, Wolkowicz R, Sperling J, Sperling R, Eisenbach L, Rotter V.
Oncogene. 14(2):145-55. 1997
145RB1
Interaction of BCR-ABL with the retinoblastoma protein in Philadelphia chromosome-positive cell lines.
Miyamura T, Nishimura J, Yufu Y, Nawata H.
Int J Hematol. 65(2):115-21. 1997
146RB1
Rb interacts with TAF(II)250/TFIID through multiple domains.
Shao Z, Siegert JL, Ruppert S, Robbins PD.
Oncogene. 15(4):385-92. 1997
147RB,RB1
A novel mutation in the promotor region in a family with a mild form of retinoblastoma indicates the location of a new regulatory domain for the RB1 gene.
Cowell JK, et al.
Oncogene 12 : 431-436. 1996
148RB,RB1
The spectrum of RB1 germ-line mutations in hereditary retinoblastoma.
Lohmann DR, et al.
Am J Hum Genet 58 : 940-949. 1996
149RB1, TSG13A
Allelic loss of the retinoblastoma tumor suppressor gene : a marker for aggressive parathyroid tumors ?
Dotzenrath C, et al.
J Clin Endocrinol Metab 81 : 3194-3196. 1996
150BRCA2, RB1, TSG13A, TSG13D
Two distinct commonly deleted regions on chromosome 13q suggest involvement of BRCA2 and retinoblastoma genes in sporadic breast carcinomas.
Tsukamoto K, et al.
Cancer 78 : 1929-1934. 1996
151LPAR6, RB1
Intron 17 of the human retinoblastoma susceptibility gene encodes an actively transcribed G protein-coupled receptor gene.
Herzog H, Darby K, Hort YJ, Shine J.
Genome Res 6(9):858-61. 1996
152RB1
Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6.
Chen PL, Riley DJ, Chen-Kiang S, Lee WH.
Proc Natl Acad Sci U S A. 93(1):465-9. 1996
153RB1
E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry.
Moberg K, Starz MA, Lees JA.
Mol Cell Biol. 16(4):1436-49. 1996
154RB1
A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock.
Chen CF, Chen Y, Dai K, Chen PL, Riley DJ, Lee WH.
Mol Cell Biol. 16(9):4691-9. 1996
155D13S25, RB1, TSG13B
Heterogeneity of deletions involving RB-1 and the D13S25 locus in B-cellchronic lymphocytic leukemia revealed by fluorescence in situ hybridization.
Stilgenbauer S, et al.
Cancer Res 55 : 3475-3477. 1995
156RB,RB1
Molecular analysis and predictive testing in retinoblastoma.
Lohmann DR, et al.
Ophthalmic Genet 16 : 135-142. 1995
157PRDM2, RB1
The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein.
Buyse IM, Shao G, Huang S.
Proc Natl Acad Sci U S A 92 : 4467-4471. 1995
158RB,RB1
Spectrum of germline mutations in the RB1 gene : a study of 232 patients with hereditary and non hereditary retinoblastoma.
Blanquet V, et al.
Hum Mol Genet 4 : 383-388. 1995
159RB1
Sequence variability of a prolonged tetranucleotide repeat.
Liu Y, et al.
Hum Mol Genet 4 : 727-729. 1995
160CDKN2A, RB1, CCND1
Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16.
Lukas J, et al.
Nature 375 : 503-506. 1995
161FRK, RB1
The nuclear tyrosine kinase Rak associates with the retinoblastoma protein pRb.
Craven RJ, Cance WG, Liu ET.
Cancer Res 55(18):3969-72. 1995
162RB1
Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast.
Qian YW, Lee EY.
J Biol Chem. 270(43):25507-13. 1995
163RB1
70-kDa heat shock cognate protein interacts directly with the N-terminal region of the retinoblastoma gene product pRb. Identification of a novel region of pRb-mediating protein interaction.
Inoue A, Torigoe T, Sogahata K, Kamiguchi K, Takahashi S, Sawada Y, Saijo M, Taya Y, Ishii S, Sato N, Kikuchi K.
J Biol Chem. 270(38):22571-6. 1995
164RB1
The retinoblastoma susceptibility gene product regulates Myc-mediated transcription.
Adnane J, Robbins PD.
Oncogene. 10(2):381-7. 1995
165RB1
Association of human Pur alpha with the retinoblastoma protein, Rb, regulates binding to the single-stranded DNA Pur alpha recognition element.
Johnson EM, Chen PL, Krachmarov CP, Barr SM, Kanovsky M, Ma ZW, Lee WH.
J Biol Chem. 270(41):24352-60. 1995
166RB1
The retinoblastoma-susceptibility gene product binds directly to the human TATA-binding protein-associated factor TAFII250.
Shao Z, Ruppert S, Robbins PD.
Proc Natl Acad Sci U S A. 92(8):3115-9. 1995
167RB,RB1
Partial inactivation of the RB product in a family with incomplete penetrance of familial retinoblastoma and benign retinal tumors.
Kratzke RA, et al.
Oncogene 9 : 1321-1326. 1994
168RB,RB1
Isolation and characterisation of a panel of cosmids which allows unequivocal identification of chromosome deletions involving the RB1 gene using fluorescence in situ hybridisation.
Cowell JK, et al.
J Med Genet 31 : 334-337. 1994
169RB,RB1
Detection of mutations of the RBI gene in retinoblastoma patients by using exon-by-exon PCR-SSCP analysis.
Shimizu T, et al.
Am J Hum Genet 54 : 793-800. 1994
170RB,RB1
Unbiased transmission of mutant alleles at the human retinoblastoma locus.
Seminara SB, et al.
Hum Genet 93 : 629-634. 1994
171RB,RB1
Three novel germline mutations in exons 8 and 18 of the retinoblastoma gene.
Blanquet V, et al.
Hum Mol Genet 3 : 1185-1186. 1994
172RB,RB1
Distinct RB1 gene mutations with low penetrance in hereditary retinoblastoma.
Lohmann DR, et al.
Hum Genet 94 : 349-354. 1994
173CDK9, RB1
PITALRE, a nuclear CDC2-related protein kinase that phosphorylates the retinoblastoma protein in vitro.
Grańa X, De Luca A, Sang N, Fu Y, Claudio PP, Rosenblatt J, Morgan DO, Giordano A.
Proc Natl Acad Sci U S A 91 : 3834-3838. 1994
174RB1
Complex formation between lamin A and the retinoblastoma gene product: identification of the domain on lamin A required for its interaction.
Ozaki T, Saijo M, Murakami K, Enomoto H, Taya Y, Sakiyama S.
Oncogene. 9(9):2649-53. 1994
175RB1, SMARCA4
The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest.
Dunaief JL, Strober BE, Guha S, Khavari PA, Alin K, Luban J, Begemann M, Crabtree GR, Goff SP.
Cell. 79(1):119-30. 1994
176RB1
The amino-terminal region of the retinoblastoma gene product binds a novel nuclear matrix protein that co-localizes to centers for RNA processing.
Durfee T, Mancini MA, Jones D, Elledge SJ, Lee WH.
J Cell Biol. 127(3):609-22. 1994
177RB,RB1
Molecular etiology of low-penetrance retinoblastoma in two pedigrees.
Dryja TP, et al.
Am J Hum Genet 52 : 1122-1128. 1993
178RB, RB1
Identification of germline mutations in the RB1 gene by denaturant gradient gel electrophoresis and polymerase chain reaction direct sequencing.
Blanquet V, et al.
Hum Mol Genet 2 : 975-979. 1993
179RB1, TSG13B
Chronic lymphocytic leukemia cells with allelic deletions at 13q14 commonly have one intact RB1 gene : evidence for a role of an adjacent locus.
Liu Y, et al.
Proc Natl Acad Sci U S A 90 : 8697-8701. 1993
180ELF1, RB1
Regulation of the Ets-related transcription factor Elf-1 by binding to the retinoblastoma protein.
Wang CY, Petryniak B, Thompson CB, Kaelin WG, Leiden JM.
Science 260(5112):1330-5 1993
181LPAR6, RB1
Complete genomic sequence of the human retinoblastoma susceptibility gene.
Toguchida J, McGee TL, Paterson JC, Eagle JR, Tucker S, Yandell DW, DryjaTP.
Genomics 17(3):535-43. 1993
182RB1
Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation.
Gu W, Schneider JW, Condorelli G, Kaushal S, Mahdavi V, Nadal-Ginard B.
Cell. 72(3):309-24. 1993
183RB1
The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB.
Hagemeier C, Bannister AJ, Cook A, Kouzarides T.
Proc Natl Acad Sci U S A. 90(4):1580-4. 1993
184RB1
Amplification and characterization of the retinoblastoma gene VNTR by PCR.
Scharf SJ, et al.
Am J Hum Genet 50 : 371-381. 1992
185RB,RB1
A new G to T polymorphism in the retinoblastoma gene RB1 detected by DGGE.
Blanquet V, et al.
Nucleic Acids Res 20 : 1432. 1992
186RB1
Detection of heterozygous mutations in the RB1 gene in retinoblastoma patients using single-strand conformation polymorphism analysis and polymerase chain reaction sequencing.
Hogg A, et al.
Oncogene 7 : 1445-1451. 1992
187RB,RB1
Oncogenic point mutations in exon 20 of the RB1 gene in families showing incomplete penetrance and mild expression of the retinoblastoma phenotype.
Onadim Z, et al.
Proc Natl Acad Sci U S A 89 : 6177-6181. 1992
188DEL13Q14,RB,RB1
Cytogenetic and molecular investigation of a balanced Xq13q translocation in a patient with retinoblastoma.
Stambolian D, et al.
Am J Med Genet 42 : 771-776. 1992
189RB1, TP53, MCC, APC, TSG5A, TSG13A, TSG17A
Loss of heterozygosity affecting the p53, Rb, and mcc/apc tumor suppressor gene loci in dysplastic and cancerous ulcerative colitis.
Greenwald BD, et al.
Cancer Res 52 : 741-745. 1992
190RB1
No alterations in exon 21 of the RB1 gene in sarcomas and carcinomas of the breast, colon, and lung.
Hovig E, et al.
Genes Chromosomes Cancer 5 : 97-103. 1992
191RB,RB1
Detection of small RB1 gene deletions in retinoblastoma by multiplex PCR and high-resolution gel electrophoresis.
Lohmann D, et al.
Hum Genet 89 : 49-53. 1992
192TP53, RB1
Human pancreatic carcinomas and cell lines reveal frequent and multiple alterations in the p53 and Rb-1 tumor-suppressor genes.
Ruggeri B, et al.
Oncogene 7 : 1503-1511. 1992
193RB1
A simple and nonradioactive method for detecting the Rb1.20 DNA polymorphism in the retinoblastoma gene.
Brandt B, et al.
Am J Hum Genet 51 : 1451-1452. 1992
194RB1
Retinoblastoma gene product activates expression of the human TGF-beta 2 gene through transcription factor ATF-2.
Kim SJ, Wagner S, Liu F, O'Reilly MA, Robbins PD, Green MR.
Nature. 358(6384):331-4. 1992
195RB1
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis.
Lee EY, Chang CY, Hu N, Wang YC, Lai CC, Herrup K, Lee WH, Bradley A.
Nature. 359(6393):288-94. 1992
196RB,RB1
Characterization of deletions at the retinoblastoma locus in patients with bilateral retinoblastoma.
Kloss K, et al.
Am J Med Genet 39 : 196-200. 1991
197RB1
Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering.
Templeton DJ, et al.
Proc Natl Acad Sci U S A 88 : 3033-3037. 1991
198RB1
Physical map around the retinoblastoma gene : possible genomic imprinting suggested by NruI digestion.
Blanquet V, et al.
Genomics 10 : 350-355. 1991
199RB1
The retinoblastoma gene functions as a growth and tumor suppressor in human bladder carcinoma cells.
Takahashi R, et al.
Proc Natl Acad Sci U S A 88 : 5257-5261. 1991
200RB1
The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle.
Goodrich DW, et al.
Cell 67 : 293-302. 1991
201RB,RB1
A familial RB1 mutation detected by the HOT technique is homozygous in a second primary neoplasm.
Weir-Thompson E, et al.
Oncogene 6 : 2353-2356. 1991
202RB1
Retinoblastoma cancer suppressor gene product is a substrate of the cell cycle regulator cdc2 kinase.
Lin BTY, et al.
EMBO J 10 : 857-864. 1991
203DEL13Q14,RB,RB1
Molecular detection of constitutional deletions in patients with retinoblastoma.
Blanquet V, Creau-Goldberg N, de Grouchy J, Turleau C.
Am J Med Genet 39(3):355-61. 1991
204RB1
The retinoblastoma protein is phosphorylated on multiple sites by human cdc2.
Lees JA, Buchkovich KJ, Marshak DR, Anderson CW, Harlow E.
EMBO J. 10(13):4279-90. 1991
205RB1
Two distinct and frequently mutated regions of retinoblastoma protein are required for binding to SV40 T antigen.
Huang S, et al.
EMBO J 9 : 1815-1822. 1990
206RB,RB1
Somatic mosaicism in a patient with bilateral retinoblastoma.
Greger V, et al.
Am J Hum Genet 46 : 1187-1193. 1990
207RB1
Altered structure and expression of the human retinoblastoma susceptibility gene in small cell lung cancer.
Hensel CH, et al.
Cancer Res 50 : 3067-3072. 1990
208RB1
PCR detection of the Tth 111 l RFLP at the RB locus.
Vaughn GL, et al.
Nucleic Acids Res 18 : 4965. 1990
209RB1
Detection by electron microscopy of a small subband 13q14.11 deletion in an hereditary retinoblastoma.
Lemieux N, et al.
Cancer Genet Cytogenet 48 : 265-269. 1990
210DEL13Q14,RB,RB1
Constitutional deletions predisposing to retinoblastoma.
Janson M, et al.
Hum Genet 85 : 21-24. 1990
211RB, RB1
Altered expression of the retinoblastoma gene product in human sarcomas.
Cance WG, et al.
N Engl J Med 323 : 1457-1462. 1990
212RB,RB1
Use of the RB1 cDNA as a diagnostic probe in retinoblastoma families.
Goddard AD, et al.
Clin Genet 37 : 117-126. 1990
213RB1
A physical map around the retinoblastoma gene.
Ford GM, et al.
Genomics 6 : 284-292. 1990
214RB1
Detection of the Xbal RFLP within the retinoblastoma locus by PCR.
McGee TL, et al.
Nucleic Acids Res 18 : 207. 1990
215RB1
PCR-based detection of a polymorphic BamHl site in intron 1 of the human retinoblastoma (RB) gene.
Bookstein R, et al.
Nucleic Acids Res 18 : 1666. 1990
216RB1
Retinoblastoma in transgenic mice.
Windle JJ, Albert DM, O'Brien JM, Marcus DM, Disteche CM, Bernards R, Mellon PL.
Nature. 343(6259):665-9. 1990
217RB1
Precise cytogenetic localization of the Rb locus at subband 13q14.11 by ultrastructural detection after immunochemical chromosome banding.
Lemieux N, et al.
Am J Hum Genet 45 : A27. 1989
218RB1
The product of retinoblastoma susceptibility gene has properties of a cell cycle regulatory element.
DeCaprio J, et al.
Cell 58 : 1085-1095. 1989
219RB1
The retinoblastoma protein is phosphorylated during specific phases of the cell cycle.
Buchkovich K, et al.
Cell 58 : 1097-1105. 1989
220RB1
Detection of DNA sequence polymorphisms in the human retinoblastoma gene by direct genomic sequencing.
Yandell DW, et al.
(HGM10) Cytogenet Cell Genet 51 : 1112. 1989
221RB,RB1
First cytogenetic evidence of homozygosity for the retinoblastoma deletion in chromosome 13.
Lemieux N, et al.
Cancer Genet Cytogenet 43 : 73-78. 1989
222RB1
Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product.
Mihara K, et al.
Science 246 : 1300-1303. 1989
223TSG13A, RB1
Human retinoblastoma gene: long-range mapping and analysis of its deletion in a breast cancer cell line.
Bookstein R, et al.
Mol Cell Biol 9 : 1628-1634. 1989
224RB1
Structure of the human retinoblastoma gene.
Hong FD, et al.
Proc Natl Acad Sci U S A 86 : 5502-5506. 1989
225RB1
Short, direct repeats at the breakpoints of deletions of the retinoblastoma gene.
Canning S, et al.
Proc Natl Acad Sci U S A 86 : 5044-5048. 1989
226ESD, RB1
Molecular evidence that the esterase-D gene lies proximal to the retinoblastoma susceptibility locus in chromosome region 13q14.
Mitchell CD, Cowell JK.
Hum Genet 81 : 57-60. 1988
227RB1
Chromosomal reorganization for the expression of recessive mutation of retinoblastoma susceptibility gene in the development of osteosarcoma.
Toguchida J, et al.
Cancer Res 48 : 3939-3943. 1988
228WND, ESD, RB1, D13S37
Partial linkage map of chromosome 13q in the region of the Wilson disease and retinoblastoma genes.
Haines JL, Ozelius L, St George-Hyslop P, Wexler NS, Gusella JF, Conneally PM.
Genet Epidemiol 5 : 375-380. 1988
229RB1
Human retinoblastoma susceptibility gene : genomic organization and analysis of heterozygous intragenic deletion mutants.
Bookstein R, et al.
Proc Natl Acad Sci U S A 85 : 2210-2214. 1988
230RB1
Prediction of the risk of hereditary retinoblastoma, using DNA polymorphisms within the retinoblastoma gene.
Wiggs J, et al.
N Engl J Med 318 : 151-157. 1988
231RB1
Types, rates, origin and expressivity of chromosome mutations involving 13q14 in retinoblastoma patients.
Ejima Y, et al.
Hum Genet 79 : 118-123. 1988
232RB1
A TaqI RFLP identified at the retinoblastoma locus on chromosome 13.
Shiang R, et al.
Nucleic Acids Res 16 : 9069. 1988
233DEL13Q14,RB,RB1
Deletion of chromosome region 13q14 is transmissible and does not always predispose to retinoblastoma.
Cowell JK, et al.
Hum Genet 80 : 43-45. 1988
234D13S25,D13S30,RB,RB1
De novo t(2;13)(p24.3;q14.2) and retinoblastoma. Mapping of two 13q14 probes by in situ hybridization.
Blanquet V, Turleau C, Creau-Goldberg N, Cochet C, de Grouchy J.
Hum Genet 76 : 102-105. 1987
235RB,RB1
Linkage analysis in retinoblastoma-prone families using highly informative RFLPs within the retinoblastoma gene.
Wiggs JL, et al.
(HGM9) Cytogenet Cell Genet 46 : 715. 1987
236RB,RB1,WND
Genetic linkage analysis of hereditary retinoblastoma and Wilson disease with chromosome 13 markers.
Scheffer H, et al.
(HGM9) Cytogenet Cell Genet 46 : 688. 1987
237RB,RB1
Balanced translocation and retinoblastoma. Demonstration of gene disruption by in situ hybridization.
Blanquet V, et al.
(HGM9) Cytogenet Cell Genet 46 : 582. 1987
238D13S22,D13S23,RB,RB1
In situ hybridization of two 13q14 probes, D13S22 and D13S23, to 13q14.1 proximal with respect to the Rb gene.
Blanquet V, et al.
(HGM9) Cytogenet Cell Genet 46 : 583. 1987
239RB,RB1
Human retinoblastoma susceptibility gene : cloning, identification, and sequence.
Lee WH, et al.
Science 235 : 1394-1399. 1987
240ESD, RB1
Re-evaluation of the sublocalization of esterase D and its relation to the retinoblastoma locus by in situ hybridization.
Duncan AMV, et al.
Cytogenet Cell Genet 44 : 153-157. 1987
241RB,RB1
Detection of submicroscopic deletions and a DNA polymorphism at the retinoblastoma locus.
Horsthemke B, et al.
Hum Genet 76 : 257-261. 1987
242RB,RB1
Familial retinoblastoma (mother and son) with 13q14 deletion.
Fukushima Y, et al.
Hum Genet 77 : 104-107. 1987
243DEL13Q14,RB,RB1
Molecular detection and differentiation of deletions in band 13q14 in human retinoblastoma.
Lalande M, et al.
Cancer Genet Cytogenet 23 : 151-157. 1986
244RB,RB1
A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma.
Friend SH, et al.
Nature 323 : 643-646. 1986
245DEL13Q14,RB,RB1
Molecular detection of deletions involving band q14 of chromosome 13 in retinoblastomas.
Dryja TP, et al.
Proc Natl Acad Sci U S A 83 : 7391-7394. 1986
246DEL13Q14,RB,RB1
Cytogenetic forms of retinoblastoma : their incidence in a survey of 66 patients.
Turleau C, et al.
Cancer Genet Cytogenet 16 : 321-334. 1985
247ESD, RB1
Location of the retinoblastoma susceptibility gene(s) and the human esterase D locus.
Ward P, Packman S, Loughman W, Sparkes M, Sparkes R, McMahon A, Gregory T, Ablin A.
J Med Genet 21(2):92-5. 1984
248DEL13Q14,RB,RB1
Retinoblastoma in a boy with a de novo mutation of a 13/18 translocation: The assumption that the retinoblastoma locus is at 13q141, particularly at the distal portion of it.
Motegi T, et al.
Hum Genet 60 : 193-195. 1982
249DEL13Q14, RB, RB1
Familial retinoblastoma and chromosome 13 deletion transmitted via insertional translocation.
Strong LC, et al.
Science 213 : 1501-1503. 1981
250RB, RB1
Etude génétique du rétinoblastome.
Briard-Guillemot ML, et al.
Humangenetik 24 : 271-284. 1974
251DEL13Q14, RB, RB1
Chromosome deletion in a case of retinoblastoma.
Lele KP, et al.
Ann Hum Genet 27 : 171-174. 1963