Citations for
1PTTG1, RASGRF1
Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells.
Manyes L, Arribas M, Gomez C, Calzada N, Fernandez-Medarde A, Santos E.
BMC Genomics 15:1019. doi: 10.1186/1471-2164-15-1019. 2014
2RASGRF1
Decreased expression of Ras-GRF1 in the brain tissue of the intractable epilepsy patients and experimental rats.
Zhu Q, Wang L, Xiao Z, Xiao F, Luo J, Zhang X, Peng X, Wang X, Sun H.
Brain Res 1493:99-109. doi: 10.1016/j.brainres.2012.11.033. Epub 2012 Nov 27. 2013
3PLCG1, RASGRF1, RASGRF2
Ras-guanine-nucleotide-releasing factors 1 and 2 interact with PLCγ at focal adhesions to enable IL-1-induced Ca(2+) signalling, ERK activation and MMP-3 expression.
Wang Q, Siminovitch KA, Downey GP, McCulloch CA.
Biochem J 449(3):771-82. doi: 10.1042/BJ20121170. 2013
4NTRK1, RASGRF1
Ras guanine nucleotide releasing factor 1 (RasGrf1) enhancement of Trk receptor-mediated neurite outgrowth requires activation of both H-Ras and Rac.
Talebian A, Robinson-Brookes K, MacDonald JI, Meakin SO.
J Mol Neurosci 49(1):38-51. doi: 10.1007/s12031-012-9847-9. Epub 2012 Jun 29. 2013
5RASGRF1
RasGRF1 regulates proliferation and metastatic behavior of human alveolar rhabdomyosarcomas.
Tarnowski M, Schneider G, Amann G, Clark G, Houghton P, Barr FG, Kenner L, Ratajczak MZ, Kucia M.
Int J Oncol 41(3):995-1004. doi: 10.3892/ijo.2012.1536. Epub 2012 Jun 28. 2012
6ARHGAP5, RASGRF1
P190A RhoGAP is required for mammary gland development.
Heckman-Stoddard BM, Vargo-Gogola T, Herrick MP, Visbal AP, Lewis MT, Settleman J, Rosen JM.
Dev Biol 360(1):1-10. doi: 10.1016/j.ydbio.2011.09.006. Epub 2011 Sep 16. 2011
7RASGRF1
Imprinted Rasgrf1 expression in neonatal mice affects olfactory learning and memory.
Drake NM, DeVito LM, Cleland TA, Soloway PD.
Genes Brain Behav 10(4):392-403. doi: 10.1111/j.1601-183X.2011.00678.x. Epub 2011 Feb 10. 2011
8RASGRF1
Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia.
Fasano S, Bezard E, D'Antoni A, Francardo V, Indrigo M, Qin L, Doveró S, Cerovic M, Cenci MA, Brambilla R.
Proc Natl Acad Sci U S A 107(50):21824-9. doi: 10.1073/pnas.1012071107. Epub 2010 Nov 29. 2010
9RASGRF1
Imprint switch mutations at Rasgrf1 support conflict hypothesis of imprinting and define a growth control mechanism upstream of IGF1.
Drake NM, Park YJ, Shirali AS, Cleland TA, Soloway PD.
Mamm Genome 20(9-10):654-63. doi: 10.1007/s00335-009-9192-7. Epub 2009 Jun 10. 2009
10RASGRF1, RASGRF2, RRAS2
Structural and spatial determinants regulating TC21 activation by RasGRF family nucleotide exchange factors.
Calvo F, Crespo P.
Mol Biol Cell 20(20):4289-302. doi: 10.1091/mbc.E09-03-0212. Epub 2009 Aug 19. 2009
11RASGRF1
Antagonism between DNA and H3K27 methylation at the imprinted Rasgrf1 locus.
Lindroth AM, Park YJ, McLean CM, Dokshin GA, Persson JM, Herman H, Pasini D, Miró X, Donohoe ME, Lee JT, Helin K, Soloway PD.
PLoS Genet 4(8):e1000145. doi: 10.1371/journal.pgen.1000145. 2008
12ARHGAP5, RASGRF1
p190A RhoGAP is a glycogen synthase kinase-3-beta substrate required for polarized cell migration.
Jiang W, Betson M, Mulloy R, Foster R, Lévay M, Ligeti E, Settleman J.
J Biol Chem 283(30):20978-88. doi: 10.1074/jbc.M802588200. Epub 2008 May 23. 2008
13RASGRF1, STMN3
SCLIP, a microtubule-destabilizing factor, interacts with RasGRF1 and inhibits its ability to promote Rac activation and neurite outgrowth.
Baldassa S, Gnesutta N, Fascio U, Sturani E, Zippel R.
J Biol Chem 282(4):2333-45. Epub 2006 Nov 29. 2007
14ARHGAP5, RASGRF1
Distinct but overlapping functions for the closely related p190 RhoGAPs in neural development.
Matheson SF, Hu KQ, Brouns MR, Sordella R, VanderHeide JD, Settleman J.
Dev Neurosci 28(6):538-50. 2006
15RASGRF1, CTCF
Rasgrf1 imprinting is regulated by a CTCF-dependent methylation-sensitive enhancer blocker.
Yoon B, Herman H, Hu B, Park YJ, Lindroth A, Bell A, West AG, Chang Y, Stablewski A, Piel JC, Loukinov DI, Lobanenkov VV, Soloway PD.
Mol Cell Biol 25(24):11184-90. 2005
16GNAS, RASGRF1
The imprinted signaling protein XL alpha s is required for postnatal adaptation to feeding.
Plagge A, Gordon E, Dean W, Boiani R, Cinti S, Peters J, Kelsey G.
Nat Genet 36(8):818-26. Epub 2004 Jul 25. 2004
17ARHGAP5, RASGRF1
p190RhoGAP is cell cycle regulated and affects cytokinesis.
Su L, Agati JM, Parsons SJ.
J Cell Biol 163(3):571-82. 2003
18RASGRF1
Structural characterization of Rasgrf1 and a novel linked imprinted locus.
de la Puente A, Hall J, Wu YZ, Leone G, Peters J, Yoon BJ, Soloway P, Plass C.
Gene 291(1-2):287-97. 2002
19RASGRF1
Identification of a human guanine nucleotide-releasing factor (H-GRF55) specific for Ras proteins.
Schweighoffer F, et al.
Oncogene 8 : 1477-1485. 1993