1 | P2RY12, RABGEF1, RASA3
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| RASA3 is a critical inhibitor of RAP1-dependent platelet activation.
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| Stefanini L, Paul DS, Robledo RF, Chan ER, Getz TM, Campbell RA, Kechele DO, Casari C, Piatt R, Caron KM, Mackman N, Weyrich AS, Parrott MC, Boulaftali Y, Adams MD, Peters LL, Bergmeier W.
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| J Clin Invest Clin Invest. 2015 Feb 23. pii: 77993. doi: 10.1172/JCI77993. [Epub ahead of print]
2015
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2 | RASA3
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| The Ras/Rap GTPase activating protein RASA3: From gene structure to in vivo functions.
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| Schurmans S, Polizzi S, Scoumanne A, Sayyed S, Molina-Ortiz P.
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| Adv Biol Regul 57:153-61. doi: 10.1016/j.jbior.2014.09.006. Epub 2014 Sep 28.
2015
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3 | RABGEF1, RASA3
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| Rasa3 controls megakaryocyte Rap1 activation, integrin signaling and differentiation into proplatelet.
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| Molina-Ortiz P, Polizzi S, Ramery E, Gayral S, Delierneux C, Oury C, Iwashita S, Schurmans S.
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| PLoS Genet 10(6):e1004420. doi: 10.1371/journal.pgen.1004420. eCollection 2014 Jun.
2014
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4 | RASA3
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| The scat mouse model highlights RASA3, a GTPase activating protein, as a key regulator of vertebrate erythropoiesis and megakaryopoiesis.
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| Peters LL, Paw BH, Blanc L.
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| Small GTPases 4(1):47-50. doi: 10.4161/sgtp.23013. Epub 2012 Dec 6.
2013
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5 | RABGEF1, RASA3
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| Critical function for the Ras-GTPase activating protein RASA3 in vertebrate erythropoiesis and megakaryopoiesis.
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| Blanc L, Ciciotte SL, Gwynn B, Hildick-Smith GJ, Pierce EL, Soltis KA, Cooney JD, Paw BH, Peters LL.
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| Proc Natl Acad Sci U S A 109(30):12099-104. doi: 10.1073/pnas.1204948109. Epub 2012 Jul 6.
2012
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6 | GNAI1, GNAIQ, RASA3
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| GAP1(IP4BP)/RASA3 mediates Galphai-induced inhibition of mitogen-activated protein kinase.
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| Nafisi H, Banihashemi B, Daigle M, Albert PR.
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| J Biol Chem 283(51):35908-17. doi: 10.1074/jbc.M803622200. Epub 2008 Oct 24.
2008
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7 | RASA3
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| Analyzing the role of the putative inositol 1,3,4,5-tetrakisphosphate receptor GAP1IP4BP in intracellular Ca2+ homeostasis.
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| Walker SA, Kupzig S, Lockyer PJ, Bilu S, Zharhary D, Cullen PJ.
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| J Biol Chem 277(50):48779-85. Epub 2002 Sep 27.
2002
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8 | ITPR3, RASA3
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| Distinct localization and function of (1,4,5)IP(3) receptor subtypes and the (1,3,4,5)IP(4) receptor GAP1(IP4BP) in highly purified human platelet membranes.
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| El-Daher SS, Patel Y, Siddiqua A, Hassock S, Edmunds S, Maddison B, PatelG, Goulding D, Lupu F, Wojcikiewicz RJ, Authi KS.
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| Blood 95(11):3412-22. Erratum in: Blood 2000 Sep 1;96(5):1684. 2000
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9 | RASA3
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| Distinct subcellular localisations of the putative inositol 1,3,4,5-tetrakisphosphate receptors GAP1IP4BP and GAP1m result from the GAP1IP4BP PH domain directing plasma membrane targeting.
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| Lockyer PJ, Bottomley JR, Reynolds JS, McNulty TJ, Venkateswarlu K,Potter BV, Dempsey CE, Cullen PJ.
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| Curr Biol 7(12):1007-10. 1997
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10 | RASA3
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| Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP1 family.
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| Cullen PJ, Hsuan JJ, Truong O, Letcher AJ, Jackson TR, Dawson AP, IrvineRF.
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| Nature 376(6540):527-30. 1995
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