Citations for
1RAP2A, RAPGEF2, STK26
The PDZ domain of the guanine nucleotide exchange factor PDZGEF directs binding to phosphatidic acid during brush border formation.
Consonni SV, Brouwer PM, van Slobbe ES, Bos JL.
PLoS One 9(5):e98253. doi: 10.1371/journal.pone.0098253. eCollection 2014. 2014
2RAP2A, RAP2C
Mechanisms of isoform specific Rap2 signaling during enterocytic brush border formation.
Bruurs LJ, Bos JL.
PLoS One 9(9):e106687. doi: 10.1371/journal.pone.0106687. eCollection 2014. 2014
3RAP1A, RAP2A
Rap1 and Rap2 antagonistically control endothelial barrier resistance.
Pannekoek WJ, Linnemann JR, Brouwer PM, Bos JL, Rehmann H.
PLoS One 8(2):e57903. doi: 10.1371/journal.pone.0057903. Epub 2013 Feb 28. 2013
4RAP2A, TNIK
Role of the Rap2/TNIK kinase pathway in regulation of LRP6 stability for Wnt signaling.
Park DS, Seo JH, Hong M, Choi SC.
Biochem Biophys Res Commun 436(2):338-43. doi: 10.1016/j.bbrc.2013.05.104. Epub 2013 Jun 4. 2013
5RAP2A
Rap2A links intestinal cell polarity to brush border formation.
Gloerich M, ten Klooster JP, Vliem MJ, Koorman T, Zwartkruis FJ, Clevers H, Bos JL.
Nat Cell Biol 14(8):793-801. doi: 10.1038/ncb2537. Epub 2012 Jul 15. 2012
6NEDD4, RAP2A, TNIK
Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development.
Kawabe H, Neeb A, Dimova K, Young SM Jr, Takeda M, Katsurabayashi S, Mitkovski M, Malakhova OA, Zhang DE, Umikawa M, Kariya K, Goebbels S, Nave KA, Rosenmund C, Jahn O, Rhee J, Brose N.
Neuron 65(3):358-72. doi: 10.1016/j.neuron.2010.01.007. 2010
7RAP2A, RAP2B, RAP2C, TNIK
Rap2 function requires palmitoylation and recycling endosome localization.
Uechi Y, Bayarjargal M, Umikawa M, Oshiro M, Takei K, Yamashiro Y, Asato T, Endo S, Misaki R, Taguchi T, Kariya K.
Biochem Biophys Res Commun 378(4):732-7. Epub 2008 Dec 4. 2009
8MINK1, RAP2A, TANC1, TNIK
MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC1.
Nonaka H, Takei K, Umikawa M, Oshiro M, Kuninaka K, Bayarjargal M, Asato T, Yamashiro Y, Uechi Y, Endo S, Suzuki T, Kariya K.
Biochem Biophys Res Commun 377(2):573-8. Epub 2008 Oct 18. 2008
9RAP2A, RAP1GAP
Rap2, but not Rap1 GTPase is expressed in human red blood cells and is involved in vesiculation.
Greco F, Ciana A, Pietra D, Balduini C, Minetti G, Torti M.
Biochim Biophys Acta 1763(3):330-5. Epub 2006 Feb 28. 2006
10RAP1A, RAP2A
Nitric oxide produced in response to engagement of beta2 integrins on human neutrophils activates the monomeric GTPases Rap1 and Rap2 and promotes adhesion.
Jenei V, Deevi RK, Adams CA, Axelsson L, Hirst DG, Andersson T, Dib K.
J Biol Chem 281(46):35008-20. Epub 2006 Sep 8. 2006
11CALM1, CDK5R1, CFHR1, FGF13, GABRB3, HBB, MAP1B, MAP2, MAP2K4, RAB6A, RAP2A, SCN2B, SORT1, SYN2, VAMP1, YWHAZ, ZBTB18
Gene regulation and DNA damage in the ageing human brain.
Lu T, Pan Y, Kao SY, Li C, Kohane I, Chan J, Yankner BA.
Nature 429(6994):883-91. Epub 2004 Jun 09. 2004
12MAP4K4, RAP2A
Mitogen-activated protein kinase kinase kinase kinase 4 as a putative effector of Rap2 to activate the c-Jun N-terminal kinase.
Machida N, Umikawa M, Takei K, Sakima N, Myagmar BE, Taira K, Uezato H, Ogawa Y, Kariya K.
J Biol Chem 279(16):15711-4. Epub 2004 Feb 13. 2004
13RAP1A, RAP2A
Rap2 as a slowly responding molecular switch in the Rap1 signaling cascade.
Ohba Y, Mochizuki N, Matsuo K, Yamashita S, Nakaya M, Hashimoto Y, Hamaguchi M, Kurata T, Nagashima K, Matsuda M.
Mol Cell Biol 20(16):6074-83. 2000
14RAP2A
Differential expression and mutation of the ras family genes in human breast cancer.
Miyakis S, Sourvinos G, Spandidos DA.
Biochem Biophys Res Commun 251 : 609-612. 1998
15RAP1A, RAP1B, RAP2A
Chromosome mapping of the human RAS-related RAP1A, RAP1B, RAP2 genes to chromosomes 1p12-p13, 12q14, and 13q34, respectively.
Rousseau-Merck MF, et al.
Cytogenet Cell Genet 53 : 2-4. 1990
16RAB3A, RAB3B, RALA, RAP1A, RAP1B, RAP2A
Chromosome mapping of the human RAS related RAB3A and RAB3B genes to chromosomes 19p13.2 and 1p31-p32, respectively.
Rousseau-Merck MF, et al.
(HGM10) Cytogenet Cell Genet 51 : 1070. 1989
17RAP1A, RAP1B, RAP2A
Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the effector region.
Pizon V, et al.
Oncogene 3 : 201-204. 1988