| 1 | RAP2A, RAPGEF2, STK26
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| The PDZ domain of the guanine nucleotide exchange factor PDZGEF directs binding to phosphatidic acid during brush border formation.
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| Consonni SV, Brouwer PM, van Slobbe ES, Bos JL.
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| PLoS One 9(5):e98253. doi: 10.1371/journal.pone.0098253. eCollection 2014.
2014
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| 2 | RAP2A, RAP2C
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| Mechanisms of isoform specific Rap2 signaling during enterocytic brush border formation.
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| Bruurs LJ, Bos JL.
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| PLoS One 9(9):e106687. doi: 10.1371/journal.pone.0106687. eCollection 2014.
2014
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| 3 | RAP1A, RAP2A
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| Rap1 and Rap2 antagonistically control endothelial barrier resistance.
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| Pannekoek WJ, Linnemann JR, Brouwer PM, Bos JL, Rehmann H.
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| PLoS One 8(2):e57903. doi: 10.1371/journal.pone.0057903. Epub 2013 Feb 28.
2013
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| 4 | RAP2A, TNIK
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| Role of the Rap2/TNIK kinase pathway in regulation of LRP6 stability for Wnt signaling.
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| Park DS, Seo JH, Hong M, Choi SC.
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| Biochem Biophys Res Commun 436(2):338-43. doi: 10.1016/j.bbrc.2013.05.104. Epub 2013 Jun 4.
2013
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| 5 | RAP2A
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| Rap2A links intestinal cell polarity to brush border formation.
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| Gloerich M, ten Klooster JP, Vliem MJ, Koorman T, Zwartkruis FJ, Clevers H, Bos JL.
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| Nat Cell Biol 14(8):793-801. doi: 10.1038/ncb2537. Epub 2012 Jul 15.
2012
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| 6 | NEDD4, RAP2A, TNIK
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| Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development.
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| Kawabe H, Neeb A, Dimova K, Young SM Jr, Takeda M, Katsurabayashi S, Mitkovski M, Malakhova OA, Zhang DE, Umikawa M, Kariya K, Goebbels S, Nave KA, Rosenmund C, Jahn O, Rhee J, Brose N.
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| Neuron 65(3):358-72. doi: 10.1016/j.neuron.2010.01.007.
2010
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| 7 | RAP2A, RAP2B, RAP2C, TNIK
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| Rap2 function requires palmitoylation and recycling endosome localization.
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| Uechi Y, Bayarjargal M, Umikawa M, Oshiro M, Takei K, Yamashiro Y, Asato T, Endo S, Misaki R, Taguchi T, Kariya K.
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| Biochem Biophys Res Commun 378(4):732-7. Epub 2008 Dec 4.
2009
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| 8 | MINK1, RAP2A, TANC1, TNIK
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| MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC1.
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| Nonaka H, Takei K, Umikawa M, Oshiro M, Kuninaka K, Bayarjargal M, Asato T, Yamashiro Y, Uechi Y, Endo S, Suzuki T, Kariya K.
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| Biochem Biophys Res Commun 377(2):573-8. Epub 2008 Oct 18.
2008
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| 9 | RAP2A, RAP1GAP
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| Rap2, but not Rap1 GTPase is expressed in human red blood cells and is involved in vesiculation.
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| Greco F, Ciana A, Pietra D, Balduini C, Minetti G, Torti M.
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| Biochim Biophys Acta 1763(3):330-5. Epub 2006 Feb 28. 2006
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| 10 | RAP1A, RAP2A
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| Nitric oxide produced in response to engagement of beta2 integrins on human neutrophils activates the monomeric GTPases Rap1 and Rap2 and promotes adhesion.
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| Jenei V, Deevi RK, Adams CA, Axelsson L, Hirst DG, Andersson T, Dib K.
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| J Biol Chem 281(46):35008-20. Epub 2006 Sep 8.
2006
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| 11 | CALM1, CDK5R1, CFHR1, FGF13, GABRB3, HBB, MAP1B, MAP2, MAP2K4, RAB6A, RAP2A, SCN2B, SORT1, SYN2, VAMP1, YWHAZ, ZBTB18
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| Gene regulation and DNA damage in the ageing human brain.
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| Lu T, Pan Y, Kao SY, Li C, Kohane I, Chan J, Yankner BA.
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| Nature 429(6994):883-91. Epub 2004 Jun 09. 2004
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| 12 | MAP4K4, RAP2A
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| Mitogen-activated protein kinase kinase kinase kinase 4 as a putative effector of Rap2 to activate the c-Jun N-terminal kinase.
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| Machida N, Umikawa M, Takei K, Sakima N, Myagmar BE, Taira K, Uezato H, Ogawa Y, Kariya K.
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| J Biol Chem 279(16):15711-4. Epub 2004 Feb 13.
2004
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| 13 | RAP1A, RAP2A
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| Rap2 as a slowly responding molecular switch in the Rap1 signaling cascade.
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| Ohba Y, Mochizuki N, Matsuo K, Yamashita S, Nakaya M, Hashimoto Y, Hamaguchi M, Kurata T, Nagashima K, Matsuda M.
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| Mol Cell Biol 20(16):6074-83. 2000
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| 14 | RAP2A
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| Differential expression and mutation of the ras family genes in human breast cancer.
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| Miyakis S, Sourvinos G, Spandidos DA.
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| Biochem Biophys Res Commun 251 : 609-612. 1998
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| 15 | RAP1A, RAP1B, RAP2A
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| Chromosome mapping of the human RAS-related RAP1A, RAP1B, RAP2 genes to chromosomes 1p12-p13, 12q14, and 13q34, respectively.
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| Rousseau-Merck MF, et al.
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| Cytogenet Cell Genet 53 : 2-4. 1990
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| 16 | RAB3A, RAB3B, RALA, RAP1A, RAP1B, RAP2A
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| Chromosome mapping of the human RAS related RAB3A and RAB3B genes to chromosomes 19p13.2 and 1p31-p32, respectively.
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| Rousseau-Merck MF, et al.
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| (HGM10) Cytogenet Cell Genet 51 : 1070. 1989
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| 17 | RAP1A, RAP1B, RAP2A
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| Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the effector region.
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| Pizon V, et al.
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| Oncogene 3 : 201-204. 1988
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