1 | MEX3B, RAP1A, RAP1GAP
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| The RNA-binding protein Mex3b regulates the spatial organization of the Rap1 pathway.
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| Le Borgne M, Chartier N, Buchet-Poyau K, Destaing O, Faurobert E, Thibert C, Rouault JP, Courchet J, Nègre D, Bouvard D, Albiges-Rizo C, Rousseaux S, Khochbin S, Segretain D, Crépieux P, Guillou F, Durand P, Perrard MH, Billaud M.
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| Development 141(10):2096-107. doi: 10.1242/dev.108514.
2014
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2 | RAP1GAP, TERF2IP
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| The small GTPase Rap1 is a novel regulator of RPE cell barrier function.
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| Wittchen ES, Hartnett ME.
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| Invest Ophthalmol Vis Sci. 52(10):7455-63. 2011
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3 | RAP1GAP, RET
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| Rap1GAP interacts with RET and suppresses GDNF-induced neurite outgrowth.
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| Jiao L, Zhang Y, Hu C, Wang YG, Huang A, He C.
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| Cell Res ell Res. 2010 Sep 28. [Epub ahead of print]PMID: 20877310 2010
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4 | RAP1GAP
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| Loss of Rap1GAP in papillary thyroid cancer.
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| Nellore A, Paziana K, Ma C, Tsygankova OM, Wang Y, Puttaswamy K, Iqbal AU, Franks SR, Lv Y, Troxel AB, Feldman MD, Meinkoth JL, Brose MS.
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| J Clin Endocrinol Metab 94(3):1026-32. Epub 2008 Dec 9.
2009
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5 | RAP1GAP, MAG
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| Rap1 is involved in the signal transduction of myelin-associated glycoprotein.
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| Taniguchi J, Fujitani M, Endo M, Kubo T, Fujitani M, Miller FD, Kaplan DR, Yamashita T.
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| Cell Death Differ 15(2):408-19. Epub 2007 Nov 30. 2008
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6 | RAP1GAP
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| Rap1GAP promotes invasion via induction of matrix metalloproteinase 9 secretion, which is associated with poor survival in low N-stage squamous cell carcinoma.
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| Mitra RS, Goto M, Lee JS, Maldonado D, Taylor JM, Pan Q, Carey TE, Bradford CR, Prince ME, Cordell KG, Kirkwood KL, D'Silva NJ.
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| Cancer Res 68(10):3959-69.PMID: 18483282 2008
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7 | IQGAP1, RAP1GAP
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| IQGAP1 binds Rap1 and modulates its activity.
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| Jeong HW, Li Z, Brown MD, Sacks DB.
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| J Biol Chem 282(28):20752-62. Epub 2007 May 21. 2007
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8 | RAP1GAP
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| Downregulation of Rap1GAP contributes to Ras transformation.
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| Tsygankova OM, Prendergast GV, Puttaswamy K, Wang Y, Feldman MD, Wang H, Brose MS, Meinkoth JL.
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| Mol Cell Biol 27(19):6647-58. Epub 2007 Jul 23.
2007
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9 | RAP1GAP
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| Identification of a putative tumor suppressor gene Rap1GAP in pancreatic cancer.
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| Zhang L, Chenwei L, Mahmood R, van Golen K, Greenson J, Li G, D'Silva NJ, Li X, Burant CF, Logsdon CD, Simeone DM.
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| Cancer Res 66(2):898-906. 2006
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10 | RAP1GAP
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| The GTPase-activating protein Rap1GAP uses a catalytic asparagine
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| Daumke O, Weyand M, Chakrabarti PP, Vetter IR, Wittinghofer A.
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| Nature. 429(6988):197-201. 2004
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11 | RAP1GAP
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| Ras and Rap1: two highly related small GTPases with distinct function.
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| Zwartkruis FJ, Bos JL.
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| Exp Cell Res 253(1):157-65. Review. 1999
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12 | RAP1GAP
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| Functional interaction between Galpha(z) and Rap1GAP suggests a novel form of cellular cross-talk.
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| Meng J, Glick JL, Polakis P, Casey PJ.
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| J Biol Chem. 274(51):36663-9. 1999
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13 | RAP1GAP
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| Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i)
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| Mochizuki N, Ohba Y, Kiyokawa E, Kurata T, Murakami T, Ozaki T, Kitabatake A, Nagashima K, Matsuda M.
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| Nature. 400(6747):891-4. 1999
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14 | RAP1GAP, SIPA1, SIPA1L1
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| Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2.
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| Kurachi H, Wada Y, Tsukamoto N, Maeda M, Kubota H, Hattori M, Iwai K, Minato N.
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| J Biol Chem 272(44):28081-8. 1997
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15 | RAP1GAP
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| The RAP1GA1 locus for human Rap1-GTPase activating protein 1 maps to chromosome 1p36.1-p35.
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| Weiss J, et al.
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| Cytogenet Cell Genet 66 : 18-21. 1994
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16 | RAP1GAP
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| Localization of the rap1GAP catalytic domain and sites of phosphorylation by mutational analysis.
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| Rubinfeld B, Crosier WJ, Albert I, Conroy L, Clark R, McCormick F, Polakis P.
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| Mol Cell Biol. 12(10):4634-42 1992
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