Citations for
1MEX3B, RAP1A, RAP1GAP
The RNA-binding protein Mex3b regulates the spatial organization of the Rap1 pathway.
Le Borgne M, Chartier N, Buchet-Poyau K, Destaing O, Faurobert E, Thibert C, Rouault JP, Courchet J, Nègre D, Bouvard D, Albiges-Rizo C, Rousseaux S, Khochbin S, Segretain D, Crépieux P, Guillou F, Durand P, Perrard MH, Billaud M.
Development 141(10):2096-107. doi: 10.1242/dev.108514. 2014
2RAP1GAP, TERF2IP
The small GTPase Rap1 is a novel regulator of RPE cell barrier function.
Wittchen ES, Hartnett ME.
Invest Ophthalmol Vis Sci. 52(10):7455-63. 2011
3RAP1GAP, RET
Rap1GAP interacts with RET and suppresses GDNF-induced neurite outgrowth.
Jiao L, Zhang Y, Hu C, Wang YG, Huang A, He C.
Cell Res ell Res. 2010 Sep 28. [Epub ahead of print]PMID: 20877310 2010
4RAP1GAP
Loss of Rap1GAP in papillary thyroid cancer.
Nellore A, Paziana K, Ma C, Tsygankova OM, Wang Y, Puttaswamy K, Iqbal AU, Franks SR, Lv Y, Troxel AB, Feldman MD, Meinkoth JL, Brose MS.
J Clin Endocrinol Metab 94(3):1026-32. Epub 2008 Dec 9. 2009
5RAP1GAP, MAG
Rap1 is involved in the signal transduction of myelin-associated glycoprotein.
Taniguchi J, Fujitani M, Endo M, Kubo T, Fujitani M, Miller FD, Kaplan DR, Yamashita T.
Cell Death Differ 15(2):408-19. Epub 2007 Nov 30. 2008
6RAP1GAP
Rap1GAP promotes invasion via induction of matrix metalloproteinase 9 secretion, which is associated with poor survival in low N-stage squamous cell carcinoma.
Mitra RS, Goto M, Lee JS, Maldonado D, Taylor JM, Pan Q, Carey TE, Bradford CR, Prince ME, Cordell KG, Kirkwood KL, D'Silva NJ.
Cancer Res 68(10):3959-69.PMID: 18483282 2008
7IQGAP1, RAP1GAP
IQGAP1 binds Rap1 and modulates its activity.
Jeong HW, Li Z, Brown MD, Sacks DB.
J Biol Chem 282(28):20752-62. Epub 2007 May 21. 2007
8RAP1GAP
Downregulation of Rap1GAP contributes to Ras transformation.
Tsygankova OM, Prendergast GV, Puttaswamy K, Wang Y, Feldman MD, Wang H, Brose MS, Meinkoth JL.
Mol Cell Biol 27(19):6647-58. Epub 2007 Jul 23. 2007
9RAP1GAP
Identification of a putative tumor suppressor gene Rap1GAP in pancreatic cancer.
Zhang L, Chenwei L, Mahmood R, van Golen K, Greenson J, Li G, D'Silva NJ, Li X, Burant CF, Logsdon CD, Simeone DM.
Cancer Res 66(2):898-906. 2006
10RAP1GAP
The GTPase-activating protein Rap1GAP uses a catalytic asparagine
Daumke O, Weyand M, Chakrabarti PP, Vetter IR, Wittinghofer A.
Nature. 429(6988):197-201. 2004
11RAP1GAP
Ras and Rap1: two highly related small GTPases with distinct function.
Zwartkruis FJ, Bos JL.
Exp Cell Res 253(1):157-65. Review. 1999
12RAP1GAP
Functional interaction between Galpha(z) and Rap1GAP suggests a novel form of cellular cross-talk.
Meng J, Glick JL, Polakis P, Casey PJ.
J Biol Chem. 274(51):36663-9. 1999
13RAP1GAP
Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i)
Mochizuki N, Ohba Y, Kiyokawa E, Kurata T, Murakami T, Ozaki T, Kitabatake A, Nagashima K, Matsuda M.
Nature. 400(6747):891-4. 1999
14RAP1GAP, SIPA1, SIPA1L1
Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2.
Kurachi H, Wada Y, Tsukamoto N, Maeda M, Kubota H, Hattori M, Iwai K, Minato N.
J Biol Chem 272(44):28081-8. 1997
15RAP1GAP
The RAP1GA1 locus for human Rap1-GTPase activating protein 1 maps to chromosome 1p36.1-p35.
Weiss J, et al.
Cytogenet Cell Genet 66 : 18-21. 1994
16RAP1GAP
Localization of the rap1GAP catalytic domain and sites of phosphorylation by mutational analysis.
Rubinfeld B, Crosier WJ, Albert I, Conroy L, Clark R, McCormick F, Polakis P.
Mol Cell Biol. 12(10):4634-42 1992