Citations for
1RAD9A, TLK1
TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint.
Awate S, De Benedetti A.
BMC Mol Biol 17:3. doi: 10.1186/s12867-016-0056-x. 2016
2DNA2, HUS1, RAD1, RAD9A, RAD9B
Lagging strand maturation factor Dna2 is a component of the replication checkpoint initiation machinery.
Kumar S, Burgers PM.
Genes Dev 27(3):313-21. doi: 10.1101/gad.204750.112. Epub 2013 Jan 25. 2013
3CHEK2, RAD9A, SLX4
DNA-repair scaffolds dampen checkpoint signalling by counteracting the adaptor Rad9.
Ohouo PY, Bastos de Oliveira FM, Liu Y, Ma CJ, Smolka MB.
Nature 493(7430):120-4. doi: 10.1038/nature11658. Epub 2012 Nov 18. 2013
4RAD9A
The DNA damage checkpoint protein RAD9A is essential for male meiosis in the mouse.
Vasileva A, Hopkins KM, Wang X, Weisbach MM, Friedman RA, Wolgemuth DJ, Lieberman HB.
J Cell Sci 126(Pt 17):3927-38. doi: 10.1242/jcs.126763. Epub 2013 Jun 20. 2013
5CHEK1, RAD9A, TLK1
Tousled-like kinase-dependent phosphorylation of Rad9 plays a role in cell cycle progression and G2/M checkpoint exit.
Kelly R, Davey SK.
PLoS One 8(12):e85859. doi: 10.1371/journal.pone.0085859. eCollection 2013. 2013
6RAD9A, RAD9B
Rad9B responds to nucleolar stress through ATR and JNK signalling, and delays the G1-S transition.
Pérez-Castro AJ, Freire R.
J Cell Sci 125(Pt 5):1152-64. Epub 2012 Mar 7. 2012
7RAD17, RAD9A
Heat induction of a novel Rad9 variant from a cryptic translation initiation site reduces mitotic commitment.
Janes S, Schmidt U, Ashour Garrido K, Ney N, Concilio S, Zekri M, Caspari T.
J Cell Sci 125(Pt 19):4487-97. doi: 10.1242/jcs.104075. Epub 2012 Jul 13. 2012
8RAD9A
Rad9 protein contributes to prostate tumor progression by promoting cell migration and anoikis resistance.
Broustas CG, Zhu A, Lieberman HB.
J Biol Chem 287(49):41324-33. doi: 10.1074/jbc.M112.402784. Epub 2012 Oct 12. 2012
9RAD9A
Reduced mRNA and protein expression of the genomic caretaker RAD9A in primary fibroblasts of individuals with childhood and independent second cancer.
Weis E, Schoen H, Victor A, Spix C, Ludwig M, Schneider-Raetzke B, Kohlschmidt N, Bartsch O, Gerhold-Ay A, Boehm N, Grus F, Haaf T, Galetzka D.
PLoS One 6(10):e25750. doi: 10.1371/journal.pone.0025750. Epub 2011 Oct 3. 2011
10CLSPN, RAD9A, RAD9B
The Rad9A checkpoint protein is required for nuclear localization of the claspin adaptor protein.
Sierant ML, Archer NE, Davey SK.
Cell Cycle 9(3):548-56. 2010
11RAD9A, TOPBP1
Rad9A is required for G2 decatenation checkpoint and to prevent endoreduplication in response to topoisomerase II inhibition.
Greer Card DA, Sierant ML, Davey S.
J Biol Chem 285(20):15653-61. Epub 2010 Mar 21. 2010
12ASF1A, RAD9A, TLK1
TLK1B promotes repair of DSBs via its interaction with Rad9 and Asf1.
Canfield C, Rains J, De Benedetti A.
BMC Mol Biol 10:110.PMID: 20021694 2009
13MLH1, RAD9A
Rad9 plays an important role in DNA mismatch repair through physical interaction with MLH1.
He W, Zhao Y, Zhang C, An L, Hu Z, Liu Y, Han L, Bi L, Xie Z, Xue P, Yang F, Hang H.
Nucleic Acids Res 36(20):6406-17. Epub 2008 Oct 8. 2008
14BBC3, BCL2L11, HUS1, RAD9A
Loss of Hus1 sensitizes cells to etoposide-induced apoptosis by regulating BH3-only proteins.
Meyerkord CL, Takahashi Y, Araya R, Takada N, Weiss RS, Wang HG.
Oncogene 27(58):7248-59. Epub 2008 Sep 15. 2008
15RAD9A
Rad9 has a functional role in human prostate carcinogenesis.
Zhu A, Zhang CX, Lieberman HB.
Cancer Res 68(5):1267-74.PMID: 18316588 2008
16COPS5, HUS1, RAD1, RAD9A
Jab1 mediates protein degradation of the Rad9-Rad1-Hus1 checkpoint complex.
Huang J, Yuan H, Lu C, Liu X, Cao X, Wan M.
J Mol Biol 371(2):514-27. Epub 2007 Jun 4. 2007
17RAD9A
Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair.
Pandita RK, Sharma GG, Laszlo A, Hopkins KM, Davey S, Chakhparonian M, Gupta A, Wellinger RJ, Zhang J, Powell SN, Roti Roti JL, Lieberman HB, Pandita TK.
Mol Cell Biol 26(5):1850-64. 2006
18HUS1, RAD1, RAD9A
Mechanism of stimulation of human DNA ligase I by the Rad9-rad1-Hus1 checkpoint complex.
Wang W, Lindsey-Boltz LA, Sancar A, Bambara RA.
J Biol Chem 281(30):20865-72. Epub 2006 May 25. 2006
19ATAD5, RAD9A
Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis.
Ishii H, Inageta T, Mimori K, Saito T, Sasaki H, Isobe M, Mori M, Croce CM, Huebner K, Ozawa K, Furukawa Y.
Proc Natl Acad Sci U S A 102(27):9655-60. Epub 2005 Jun 27. 2005
20RAD9A, CDKN1a
Human RAD9 checkpoint control/proapoptotic protein can activate transcription of p21.
Yin Y, Zhu A, Jin YJ, Liu YX, Zhang X, Hopkins KM, Lieberman HB.
Proc Natl Acad Sci U S A 101(24):8864-9. Epub 2004 Jun 07. 2004
21RAD1, HUS1, RAD9A
The human Rad9-Rad1-Hus1 checkpoint complex stimulates flap endonuclease 1.
Wang W, Brandt P, Rossi ML, Lindsey-Boltz L, Podust V, Fanning E, Sancar A, Bambara RA.
Proc Natl Acad Sci U S A 101(48):16762-7. Epub 2004 Nov 19. 2004
22HUS1B, RAD1, RAD9A, RAD9B
Identification and characterization of RAD9B, a paralog of the RAD9 checkpoint gene.
Dufault VM, Oestreich AJ, Vroman BT, Karnitz LM.
Genomics 82(6):644-51. 2003
23RAD9A
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin.
Zou L, Cortez D, Elledge SJ.
Genes Dev 16(2):198-208. 2002
24RAD9A
ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation.
Chen MJ, Lin YT, Lieberman HB, Chen G, Lee EY.
J Biol Chem 276(19):16580-6. Epub 2001 Feb 06. 2001
25RAD9A
Reconstitution and molecular analysis of the hRad9-hHus1-hRad1 (9-1-1) DNA damage responsive checkpoint complex.
Burtelow MA, Roos-Mattjus PM, Rauen M, Babendure JR, Karnitz LM.
J Biol Chem 276(28):25903-9. Epub 2001 May 04. 2001
26HUS1, RAD1, RAD9A
Physical interactions among human checkpoint control proteins HUS1p, RAD1p, and RAD9p, and implications for the regulation of cell cycle progression.
Hang H, Lieberman HB.
Genomics 65(1):24-33. 2000
27RAD9A
Human DNA damage checkpoint protein hRAD9 is a 3' to 5' exonuclease.
Bessho T, Sancar A.
J Biol Chem 275(11):7451-4. 2000
28RAD9A
Retention of the human Rad9 checkpoint complex in extraction-resistant nuclear complexes after DNA damage.
Burtelow MA, Kaufmann SH, Karnitz LM.
J Biol Chem 275(34):26343-8. 2000
29RAD9A
The human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1, and hRad9.
Rauen M, Burtelow MA, Dufault VM, Karnitz LM.
J Biol Chem 275(38):29767-71. 2000
30RAD9A
PCNA interacts with hHus1/hRad9 in response to DNA damage and replication inhibition.
Komatsu K, Wharton W, Hang H, Wu C, Singh S, Lieberman HB, Pledger WJ,Wang HG.
Oncogene 19(46):5291-7. 2000
31HUS1, RAD9A
Human homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complex.
Volkmer E, Karnitz LM.
J Biol Chem 274(2):567-70. 1999
32RAD9A
The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1.
St Onge RP, Udell CM, Casselman R, Davey S.
Mol Biol Cell 10(6):1985-95. 1999
33BRCA1, DNTT, ECT2, MDM4, RAD9A, XPC, XRCC1
From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair.
Callebaut I, et al.
FEBS Lett 400(1):25-30. 1997
34BRCA1, DNTT, ECT2, MDM4, RAD9A, XRCC1
A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins.
Bork P, et al.
FASEB J 11(1):68-76. 1997
35RAD9B, RAD9A
A human homolog of the Schizosaccharomyces pombe rad9+ checkpoint control gene.
Lieberman HB, Hopkins KM, Nass M, Demetrick D, Davey S.
Proc Natl Acad Sci U S A 93(24):13890-5. 1996