| 1 | RAD51, TOPORS
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| TOPORS-mediated RAD51 SUMOylation facilitates homologous recombination repair.
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| Nucleic Acids Res. Feb 22;50(3):1501-1516. doi: 10.1093/nar/gkac009. 2022
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| 2 | ATRX, BRD9, RAD51
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| The bromodomain containing protein BRD-9 orchestrates RAD51-RAD54 complex formation and regulates homologous recombination-mediated repair.
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| Zhou Q, Huang J, Zhang C, Zhao F, Kim W, Tu X, Zhang Y, Nowsheen S, Zhu Q, Deng M, Chen Y, Qin B, Luo K, Liu B, Lou Z, Mutter RW, Yuan J.
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| Nat Commun. May 26;11(1):2639. doi: 10.1038/s41467-020-16443-x 2020
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| 3 | BRME1, HSF2BP, RAD51
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| MEIOK21: a new component of meiotic recombination bridges required for spermatogenesis
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| Shang Y, Huang T, Liu H, Liu Y, Liang H, Yu X, Li M, Zhai B, Yang X, Wei Y, Wang G, Chen Z, Wang S, Zhang L
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| Nucleic Acids Res. Jul 9;48(12):6624-6639. doi: 10.1093/nar/gkaa406. 2020
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| 4 | ATRIP, ETAA1, RAD51, RPA1, TP53
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| Replication protein A: a multifunctional protein with roles in DNA replication, repair and beyond. 2020 PMID:
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| Dueva R, Iliakis G.
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| NAR Cancer. Sep 25;2(3):zcaa022. doi: 10.1093/narcan/zcaa022. 2020
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| 5 | E2F7, RAD51
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| An E2F7-dependent transcriptional program modulates DNA damage repair and genomic stability
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| Mitxelena J, Apraiz A, Vallejo-Rodríguez J, García-Santisteban I, Fullaondo A, Alvarez-Fernández M, Malumbres M, Zubiaga AM
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| Nucleic Acids Res. May 18;46(9):4546-4559. doi: 10.1093/nar/gky218. Erratum in: Nucleic Acids Res. 2019 Aug 22;47(14):7716-7717 2018
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| 6 | EME1, MUS81, RAD51, RECQL5
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| RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis.
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| Di Marco S, Hasanova Z, Kanagaraj R, Chappidi N, Altmannova V, Menon S, Sedlackova H, Langhoff J, Surendranath K, Hühn D, Bhowmick R, Marini V, Ferrari S, Hickson ID, Krejci L, Janscak P.
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| Mol Cell 66(5):658-671.e8. doi: 10.1016/j.molcel.2017.05.006.
2017
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| 7 | NEK8, RAD51
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| NEK8 regulates DNA damage-induced RAD51 foci formation and replication fork protection.
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| Abeyta A, Castella M, Jacquemont C, Taniguchi T.
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| Cell Cycle 16(4):335-347. doi: 10.1080/15384101.2016.1259038. Epub 2016 Nov 28.
2017
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| 8 | DMC1, RAD51, SYCP3
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| SYCP3 regulates strand invasion activities of RAD51 and DMC1.
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| Kobayashi W, Hosoya N, Machida S, Miyagawa K, Kurumizaka H.
|
| Genes Cells 22(9):799-809. doi: 10.1111/gtc.12513. Epub 2017 Jul 26.
2017
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| 9 | BARD1, BRCA1, RAD51
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| BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing.
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| Zhao W, Steinfeld JB, Liang F, Chen X, Maranon DG, Jian Ma C, Kwon Y, Rao T, Wang W, Sheng C, Song X, Deng Y, Jimenez-Sainz J, Lu L, Jensen RB, Xiong Y, Kupfer GM, Wiese C, Greene EC, Sung P.
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| Nature. Oct 19;550(7676):360-365. doi: 10.1038/nature24060. Epub 2017 Oct 4. 2017
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| 10 | BRCA1, FANCR, FANCS, FANCT, FANCU, FANCV, MAD2L2, RAD51, RAD51B, RAD51C, RAD51D, REV3L, UBE2T, XRCC2
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| Recent discoveries in the molecular pathogenesis of the inherited bone marrow failure syndrome Fanconi anemia.
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| Mamrak NE, Shimamura A, Howlett NG.
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| Blood Rev lood Rev. 2016 Oct 13. pii: S0268-960X(16)30054-6. doi: 10.1016/j.blre.2016.10.002. Review.
2016
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| 11 | LIG4, RAD51, XRCC4
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| Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans.
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| Li Z, Zhang W, Chen Y, Guo W, Zhang J, Tang H, Xu Z, Zhang H, Tao Y, Wang F, Jiang Y, Sun FL, Mao Z.
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| Cell Death Differ 23(11):1765-1777. doi: 10.1038/cdd.2016.65.
2016
|
| 12 | RAD51
|
| RAD51 regulates CHK1 stability via autophagy to promote cell growth in esophageal squamous carcinoma cells.
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| Zhu X, Pan Q, Huang N, Wu J, Zhen N, Sun F, Li Z, Yang Q.
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| Tumour Biol umour Biol. 2016 Oct 14.
2016
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| 13 | PLK1, RAD51, TOPBP1
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| TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity.
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| Moudry P, Watanabe K, Wolanin KM, Bartkova J, Wassing IE, Watanabe S, Strauss R, Troelsgaard Pedersen R, Oestergaard VH, Lisby M, Andújar-Sánchez M, Maya-Mendoza A, Esashi F, Lukas J, Bartek J.
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| J Cell Biol 212(3):281-8. doi: 10.1083/jcb.201507042.
2016
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| 14 | DMC1, RAD51
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| Chromatin architecture may dictate the target site for DMC1, but not for RAD51, during homologous pairing.
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| Kobayashi W, Takaku M, Machida S, Tachiwana H, Maehara K, Ohkawa Y, Kurumizaka H.
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| Sci Rep 6:24228. doi: 10.1038/srep24228.
2016
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| 15 | BRCA2, DMC1, RAD51
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| BRCA2 regulates DMC1-mediated recombination through the BRC repeats.
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| Martinez JS, von Nicolai C, Kim T, Ehlén Å, Mazin AV, Kowalczykowski SC, Carreira A.
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| Proc Natl Acad Sci U S A 113(13):3515-20. doi: 10.1073/pnas.1601691113.
2016
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| 16 | MMS22L, RAD51, TONSL
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| The MMS22L-TONSL heterodimer directly promotes RAD51-dependent recombination upon replication stress.
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| Piwko W, Mlejnkova LJ, Mutreja K, Ranjha L, Stafa D, Smirnov A, Brodersen MM, Zellweger R, Sturzenegger A, Janscak P, Lopes M, Peter M, Cejka P.
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| EMBO J 35(23):2584-2601. Epub 2016 Oct 26.
2016
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| 17 | NEK1, RAD51
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| Nek1 Regulates Rad54 to Orchestrate Homologous Recombination and Replication Fork Stability.
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| Spies J, Waizenegger A, Barton O, Sürder M, Wright WD, Heyer WD, Löbrich M.
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| Mol Cell. Jun 16;62(6):903-917. doi: 10.1016/j.molcel.2016.04.032. Epub 2016 Jun 2. 2016
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| 18 | CSE1L, RAD51
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| hCAS/CSE1L regulates RAD51 distribution and focus formation for homologous recombinational repair.
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| Okimoto S, Sun J, Fukuto A, Horikoshi Y, Matsuda S, Matsuda T, Ikura M, Ikura T, Machida S, Kurumizaka H, Miyamoto Y, Oka M, Yoneda Y, Kiuchi Y, Tashiro S.
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| Genes Cells 20(9):681-94. doi: 10.1111/gtc.12262.
2015
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| 19 | DMC1, RAD51
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| Functional Relationship of ATP Hydrolysis, Presynaptic Filament Stability, and Homologous DNA Pairing Activity of the Human Meiotic Recombinase DMC1.
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| Chang HY, Liao CY, Su GC, Lin SW, Wang HW, Chi P.
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| J Biol Chem 290(32):19863-73. doi: 10.1074/jbc.M115.666289.
2015
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| 20 | MMVC2, RAD51
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| Congenital mirror movements: phenotypes associated with DCC and RAD51 mutations.
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| Franz EA, Chiaroni-Clarke R, Woodrow S, Glendining KA, Jasoni CL, Robertson SP, Gardner RJ, Markie D.
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| J Neurol Sci 351(1-2):140-5. doi: 10.1016/j.jns.2015.03.006.
2015
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| 21 | ATM, RAD51
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| Involvement of ATM in homologous recombination after end resection and RAD51 nucleofilament formation.
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| Bakr A, Oing C, Köcher S, Borgmann K, Dornreiter I, Petersen C, Dikomey E, Mansour WY.
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| Nucleic Acids Res 43(6):3154-66. doi: 10.1093/nar/gkv160.
2015
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| 22 | FBXO18, RAD51
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| FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51.
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| Chu WK, Payne MJ, Beli P, Hanada K, Choudhary C, Hickson ID.
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| Nat Commun 6:5931. doi: 10.1038/ncomms6931.
2015
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| 23 | RAD51
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| Tumor-associated mutations in a conserved structural motif alter physical and biochemical properties of human RAD51 recombinase.
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| Chen J, Morrical MD, Donigan KA, Weidhaas JB, Sweasy JB, Averill AM, Tomczak JA, Morrical SW.
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| Nucleic Acids Res 43(2):1098-111. doi: 10.1093/nar/gku1337.
2015
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| 24 | DMC1, RAD51
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| Small Rad51 and Dmc1 Complexes Often Co-occupy Both Ends of a Meiotic DNA Double Strand Break.
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| Brown MS, Grubb J, Zhang A, Rust MJ, Bishop DK.
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| PLoS Genet 11(12):e1005653. doi: 10.1371/journal.pgen.1005653.
2015
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| 25 | MND1, PSMC3IP, RAD51
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| Crystal structure of Hop2-Mnd1 and mechanistic insights into its role in meiotic recombination.
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| Kang HA, Shin HC, Kalantzi AS, Toseland CP, Kim HM, Gruber S, Peraro MD, Oh BH.
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| Nucleic Acids Res 43(7):3841-56. doi: 10.1093/nar/gkv172.
2015
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| 26 | RAD51
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| Rad51 regulates cell cycle progression by preserving G2/M transition in mouse embryonic stem cells.
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| Yoon SW, Kim DK, Kim KP, Park KS.
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| Stem Cells Dev 23(22):2700-11. doi: 10.1089/scd.2014.0129.
2014
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| 27 | MND1, PSMC3IP, RAD51
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| HOP2-MND1 modulates RAD51 binding to nucleotides and DNA.
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| Bugreev DV, Huang F, Mazina OM, Pezza RJ, Voloshin ON, Camerini-Otero RD, Mazin AV.
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| Nat Commun 5:4198. doi: 10.1038/ncomms5198.
2014
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| 28 | MMVC2, RAD51
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| Congenital mirror movements: mutational analysis of RAD51 and DCC in 26 cases.
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| Méneret A, Depienne C, Riant F, Trouillard O, Bouteiller D, Cincotta M, Bitoun P, Wickert J, Lagroua I, Westenberger A, Borgheresi A, Doummar D, Romano M, Rossi S, Defebvre L, De Meirleir L, Espay AJ, Fiori S, Klebe S, Quélin C, Rudnik-Schöneborn S, Plessis G, Dale RC, Sklower Brooks S, Dziezyc K, Pollak P, Golmard JL, Vidailhet M, Brice A, Roze E.
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| Neurology 82(22):1999-2002. doi: 10.1212/WNL.0000000000000477.
2014
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| 29 | RAD51
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| Regulation of Rad51 promoter.
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| Hine CM, Li H, Xie L, Mao Z, Seluanov A, Gorbunova V.
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| Cell Cycle 13(13):2038-45. doi: 10.4161/cc.29016.
2014
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| 30 | AGO2, RAD51
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| Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombination.
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| Gao M, Wei W, Li MM, Wu YS, Ba Z, Jin KX, Li MM, Liao YQ, Adhikari S, Chong Z, Zhang T, Guo CX, Tang TS, Zhu BT, Xu XZ, Mailand N, Yang YG, Qi Y, Rendtlew Danielsen JM.
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| Cell Res 24(5):532-41. doi: 10.1038/cr.2014.36. 2014
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| 31 | DMC1, RAD51
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| Down-regulation of Rad51 activity during meiosis in yeast prevents competition with Dmc1 for repair of double-strand breaks.
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| Liu Y, Gaines WA, Callender T, Busygina V, Oke A, Sung P, Fung JC, Hollingsworth NM.
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| PLoS Genet 10(1):e1004005. doi: 10.1371/journal.pgen.1004005.
2014
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| 32 | MND1, PSMC3IP, RAD51
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| Interchromosomal homology searches drive directional ALT telomere movement and synapsis.
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| Cho NW, Dilley RL, Lampson MA, Greenberg RA.
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| Cell 159(1):108-21. doi: 10.1016/j.cell.2014.08.030.
2014
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| 33 | BRCA2, RAD51
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| Structure and mechanism of action of the BRCA2 breast cancer tumor suppressor.
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| Shahid T, Soroka J, Kong EH, Malivert L, McIlwraith MJ, Pape T, West SC, Zhang X.
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| Nat Struct Mol Biol 21(11):962-8. doi: 10.1038/nsmb.2899.
2014
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| 34 | BRCA2, PLK1, RAD51
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| BRCA2 coordinates the activities of cell-cycle kinases to promote genome stability.
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| Yata K, Bleuyard JY, Nakato R, Ralf C, Katou Y, Schwab RA, Niedzwiedz W, Shirahige K, Esashi F.
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| Cell Rep 7(5):1547-59. doi: 10.1016/j.celrep.2014.04.023.
2014
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| 35 | RAD51, RAD52
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| RAD52 inactivation is synthetically lethal with deficiencies in BRCA1 and PALB2 in addition to BRCA2 through RAD51-mediated homologous recombination.
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| Lok BH, Carley AC, Tchang B, Powell SN.
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| Oncogene 32(30):3552-8. doi: 10.1038/onc.2012.391. Epub 2012 Sep 10.
2013
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| 36 | FANCD2, HELQ, RAD51
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| HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis.
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| Adelman CA, Lolo RL, Birkbak NJ, Murina O, Matsuzaki K, Horejsi Z, Parmar K, Borel V, Skehel JM, Stamp G, D'Andrea A, Sartori AA, Swanton C, Boulton SJ.
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| Nature 502(7471):381-4. doi: 10.1038/nature12565. Epub 2013 Sep 4.
2013
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| 37 | FBXO18, RAD51
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| FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells.
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| Simandlova J, Zagelbaum J, Payne MJ, Chu WK, Shevelev I, Hanada K, Chatterjee S, Reid DA, Liu Y, Janscak P, Rothenberg E, Hickson ID.
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| J Biol Chem 288(47):34168-80. doi: 10.1074/jbc.M113.484493. Epub 2013 Oct 9.
2013
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| 38 | MCM8, MCM9, RAD51
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| The MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination.
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| Park J, Long DT, Lee KY, Abbas T, Shibata E, Negishi M, Luo Y, Schimenti JC, Gambus A, Walter JC, Dutta A.
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| Mol Cell Biol 33(8):1632-44. doi: 10.1128/MCB.01503-12. Epub 2013 Feb 11.
2013
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| 39 | BLM, RAD51, SPIDR
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| Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair.
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| Wan L, Han J, Liu T, Dong S, Xie F, Chen H, Huang J.
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| Proc Natl Acad Sci U S A 110(26):10646-51. doi: 10.1073/pnas.1220921110. Epub 2013 Mar 18.
2013
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| 40 | DMC1, RAD51
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| Meiotic crossover control by concerted action of Rad51-Dmc1 in homolog template bias and robust homeostatic regulation.
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| Lao JP, Cloud V, Huang CC, Grubb J, Thacker D, Lee CY, Dresser ME, Hunter N, Bishop DK.
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| PLoS Genet 9(12):e1003978. doi: 10.1371/journal.pgen.1003978.
2013
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| 41 | BRCA2, RAD51
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| Endogenous levels of Rad51 and Brca2 are required for homologous recombination and regulated by homeostatic re-balancing.
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| Magwood AC, Malysewich MJ, Cealic I, Mundia MM, Knapp J, Baker MD.
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| DNA Repair (Amst) 12(12):1122-33. doi: 10.1016/j.dnarep.2013.10.006.
2013
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| 42 | ATRX, RAD51
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| Analysis of the activities of RAD54, a SWI2/SNF2 protein, using a specific small-molecule inhibitor
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| Deakyne JS, Huang F, Negri J, Tolliday N, Cocklin S, Mazin AV.
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| J Biol Chem. Nov 1;288(44):31567-80. doi: 10.1074/jbc.M113.502195. Epub 2013 Sep 16. 2013
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| 43 | MMVC2, RAD51
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| RAD51 Haploinsufficiency Causes Congenital Mirror Movements in Humans.
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| Depienne C, Bouteiller D, Méneret A, Billot S, Groppa S, Klebe S, Charbonnier-Beaupel F, Corvol JC, Saraiva JP, Brueggemann N, Bhatia K, Cincotta M, Brochard V, Flamand-Roze C, Carpentier W, Meunier S, Marie Y, Gaussen M, Stevanin G, Wehrle R, Vidailhet M, Klein C, Dusart I, Brice A, Roze E.
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| Am J Hum Genet 90(2):301-7. Epub 2012 Feb 2.
2012
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| 44 | RAD51
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| RAD51 protein ATP cap regulates nucleoprotein filament stability.
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| Amunugama R, He Y, Willcox S, Forties RA, Shim KS, Bundschuh R, Luo Y, Griffith J, Fishel R.
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| J Biol Chem 287(12):8724-36. doi: 10.1074/jbc.M111.239426. Epub 2012 Jan 24.
2012
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| 45 | PLK1, RAD51
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| Plk1 and CK2 act in concert to regulate Rad51 during DNA double strand break repair.
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| Yata K, Lloyd J, Maslen S, Bleuyard JY, Skehel M, Smerdon SJ, Esashi F.
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| Mol Cell 45(3):371-83. doi: 10.1016/j.molcel.2011.12.028.
2012
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| 46 | EP400, RAD51
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| The chromatin remodeler p400 ATPase facilitates Rad51-mediated repair of DNA double-strand breaks.
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| Courilleau C, Chailleux C, Jauneau A, Grimal F, Briois S, Boutet-Robinet E, Boudsocq F, Trouche D, Canitrot Y.
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2012
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| 47 | RAD51
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| RAD51 mutants cause replication defects and chromosomal instability.
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| Kim TM, Ko JH, Hu L, Kim SA, Bishop AJ, Vijg J, Montagna C, Hasty P.
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| Mol Cell Biol 32(18):3663-80. doi: 10.1128/MCB.00406-12. Epub 2012 Jul 9.
2012
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| 48 | DMC1, RAD51
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| Rad51 is an accessory factor for Dmc1-mediated joint molecule formation during meiosis.
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| Cloud V, Chan YL, Grubb J, Budke B, Bishop DK.
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| Science 337(6099):1222-5. doi: 10.1126/science.1219379.
2012
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| 49 | RAD51, SFR1, SWI5
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| The role of the human SWI5-MEI5 complex in homologous recombination repair.
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| Yuan J, Chen J.
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| J Biol Chem 286(11):9888-93. Epub 2011 Jan 20.
2011
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| 50 | RAD51
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| Cooperation of RAD51 and RAD54 in regression of a model replication fork.
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| Bugreev DV, Rossi MJ, Mazin AV.
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2011
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| 51 | RAD51, XRCC1, XRCC2
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| Homologous recombination proteins are associated with centrosomes and are required for mitotic stability.
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| 52 | BRCA2, MRE11A, RAD51
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| Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.
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| Schlacher K, Christ N, Siaud N, Egashira A, Wu H, Jasin M.
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| Cell 145(4):529-42. Erratum in: Cell. 2011 Jun 10;145(6):993.
2011
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| 53 | BRCA2, RAD51
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| Valine 1532 of human BRC repeat 4 plays an important role in the interaction between BRCA2 and RAD51.
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| Ochiai K, Yoshikawa Y, Yoshimatsu K, Oonuma T, Tomioka Y, Takeda E, Arikawa J, Mominoki K, Omi T, Hashizume K, Morimatsu M.
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2011
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| 54 | BRCA2, RAD51
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| Two classes of BRC repeats in BRCA2 promote RAD51 nucleoprotein filament function by distinct mechanisms.
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2011
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| 55 | FANCD2, FANCI, RAD51
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| Mechanism of RAD51-dependent DNA interstrand cross-link repair.
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| Science 333(6038):84-7.
2011
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| 56 | RAD51
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| Regulation of Rad51 function by phosphorylation.
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| EMBO Rep 12(8):833-9. doi: 10.1038/embor.2011.127.
2011
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| 57 | CDK1, RAD51, RBBP8
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| Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair.
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2011
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| 58 | RAD51
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| Overexpression of RAD51 suppresses recombination defects: a possible mechanism to reverse genomic instability.
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2010
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| 59 | RAD51, SFPQ
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| The splicing-factor related protein SFPQ/PSF interacts with RAD51D and is necessary for homology-directed repair and sister chromatid cohesion.
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| 60 | RAD51, RAD51C, XRCC3
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| Discovery of a novel function for human Rad51: maintenance of the mitochondrial genome.
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| 61 | GEMIN2, RAD51
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| GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination.
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| 62 | ATM, ATR, RAD51, WRN
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| ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery.
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| 63 | BRCA2, RAD51
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| Purified human BRCA2 stimulates RAD51-mediated recombination.
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2010
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| 64 | BRCA2, PALB2, PARP1, RAD51
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| Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination.
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2010
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| 65 | PALB2, RAD51, RAD51AP1
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| Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.
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2010
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| 66 | BRCA2, RAD51
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| BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping.
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2010
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| 67 | RAD51
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| Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis.
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2010
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| 68 | RAD51, XRCC2
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| The importance of XRCC2 in RAD51-related DNA damage repair.
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2010
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| 69 | BRCA2, RAD51
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| The BRC Repeats of BRCA2 Modulate the DNA-Binding Selectivity of RAD51
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