| 1 | CDLS4, RAD21
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| Novel mosaic variants in two patients with Cornelia de Lange syndrome.
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| Pozojevic J, Parenti I, Graul-Neumann L, Ruiz Gil S, Watrin E, Wendt KS, Werner R, Strom TM, Gillessen-Kaesbach G, Kaiser FJ.
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| Eur J Med Genet ur J Med Genet. 2017 Nov 15. pii: S1769-7212(17)30498-6. doi: 10.1016/j.ejmg.2017.11.004. [Epub ahead of print]
2017
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| 2 | RAD21
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| Deregulation of KSHV latency conformation by ER-stress and caspase-dependent RAD21-cleavage.
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| De Leo A, Chen HS, Hu CA, Lieberman PM.
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| PLoS Pathog 13(8):e1006596. doi: 10.1371/journal.ppat.1006596. eCollection 2017 Aug.
2017
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| 3 | RAD21, TP53
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| Mutant p53 stimulates cell invasion through an interaction with Rad21 in human ovarian cancer cells.
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| Ahn JH, Kim TJ, Lee JH, Choi JH.
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| Sci Rep 7(1):9076. doi: 10.1038/s41598-017-08880-4.
2017
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| 4 | CDLS, CDLS2, CDLS4, CDLS5, CDLSX, HDAC8, NIPBL, RAD21, SMC1A, SMC3
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| Impairment of Retinoic Acid Signaling in Cornelia de Lange Syndrome Fibroblasts.
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| Fazio G, Bettini LR, Rigamonti S, Meta D, Biondi A, Cazzaniga G, Selicorni A, Massa V.
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| Birth Defects Res 109(16):1268-1276. doi: 10.1002/bdr2.1070. Epub 2017 Jul 28.
2017
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| 5 | RAD21, SMC1A, SMC3, STAG1, STAG2
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| Two-step ATP-driven opening of cohesin head.
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| Marcos-Alcalde Í, Mendieta-Moreno JI, Puisac B, Gil-Rodríguez MC, Hernández-Marcos M, Soler-Polo D, Ramos FJ, Ortega J, Pié J, Mendieta J, Gómez-Puertas P.
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| Sci Rep 7(1):3266. doi: 10.1038/s41598-017-03118-9.
2017
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| 6 | CDLS4, RAD21
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| A novel RAD21 variant associated with intrafamilial phenotypic variation in Cornelia de Lange syndrome - review of the literature.
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| Boyle MI, Jespersgaard C, Nazaryan L, Bisgaard AM, Tümer Z.
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| Clin Genet 91(4):647-649. doi: 10.1111/cge.12863. Epub 2016 Nov 24.
2017
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| 7 | CTCF, RAD21
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| Different distribution of histone modifications in genes with unidirectional and bidirectional transcription and a role of CTCF and cohesin in directing transcription.
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| Bornelöv S, Komorowski J, Wadelius C.
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| BMC Genomics 16:300. doi: 10.1186/s12864-015-1485-5.
2015
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| 8 | RAD21
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| Mutations in RAD21 disrupt regulation of APOB in patients with chronic intestinal pseudo-obstruction.
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| Bonora E, Bianco F, Cordeddu L, Bamshad M, Francescatto L, Dowless D, Stanghellini V, Cogliandro RF, Lindberg G, Mungan Z, Cefle K, Ozcelik T, Palanduz S, Ozturk S, Gedikbasi A, Gori A, Pippucci T, Graziano C, Volta U, Caio G, Barbara G, D'Amato M, Seri M, Katsanis N, Romeo G, De Giorgio R.
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| Gastroenterology 148(4):771-782.e11. doi: 10.1053/j.gastro.2014.12.034. Epub 2015 Jan 6.
2015
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| 9 | RAD21, SMC3, WAPL
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| Characterization of a DNA exit gate in the human cohesin ring.
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| Huis in 't Veld PJ, Herzog F, Ladurner R, Davidson IF, Piric S, Kreidl E, Bhaskara V, Aebersold R, Peters JM.
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| Science 346(6212):968-72. doi: 10.1126/science.1256904.
2014
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| 10 | CDLS4, RAD21
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| Two novel RAD21 mutations in patients with mild Cornelia de Lange syndrome-like presentation and report of the first familial case.
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| Minor A, Shinawi M, Hogue JS, Vineyard M, Hamlin DR, Tan C, Donato K, Wysinger L, Botes S, Das S, Del Gaudio D.
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| Gene 537(2):279-84. doi: 10.1016/j.gene.2013.12.045. Epub 2013 Dec 27.
2014
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| 11 | RAD21, SMC1A, SMC3, STAG2
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| Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
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| Kon A, Shih LY, Minamino M, Sanada M, Shiraishi Y, Nagata Y, Yoshida K, Okuno Y, Bando M, Nakato R, Ishikawa S, Sato-Otsubo A, Nagae G, Nishimoto A, Haferlach C, Nowak D, Sato Y, Alpermann T, Nagasaki M, Shimamura T, Tanaka H, Chiba K, Yamamoto R, Yamaguchi T, Otsu M, Obara N, Sakata-Yanagimoto M, Nakamaki T, Ishiyama K, Nolte F, Hofmann WK, Miyawaki S, Chiba S, Mori H, Nakauchi H, Koeffler HP, Aburatani H, Haferlach T, Shirahige K, Miyano S, Ogawa S.
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| Nat Genet 45(10):1232-7. doi: 10.1038/ng.2731. Epub 2013 Aug 18.
2013
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| 12 | RAD21, SMC1A, SMC3
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| Knocking down SMC1A inhibits growth and leads to G2/M arrest in human glioma cells.
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| Ma Z, Lin M, Li K, Fu Y, Liu X, Yang D, Zhao Y, Zheng J, Sun B.
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| Int J Clin Exp Pathol 6(5):862-9. Print 2013.
2013
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| 13 | RAD21, STAG1, STAG2
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| Characterization of the interaction between the cohesin subunits Rad21 and SA1/2.
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| Zhang N, Jiang Y, Mao Q, Demeler B, Tao YJ, Pati D.
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| PLoS One 8(7):e69458. doi: 10.1371/journal.pone.0069458. Print 2013. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/69ab23f6-7d9 2013
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| 14 | CDLS4, RAD21
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| RAD21 Mutations Cause a Human Cohesinopathy.
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| Deardorff MA, Wilde JJ, Albrecht M, Dickinson E, Tennstedt S, Braunholz D, Mönnich M, Yan Y, Xu W, Gil-Rodríguez MC, Clark D, Hakonarson H, Halbach S, Michelis LD, Rampuria A, Rossier E, Spranger S, Van Maldergem L, Lynch SA, Gillessen-Kaesbach G, Lüdecke HJ, Ramsay RG, McKay MJ, Krantz ID, Xu H, Horsfield JA, Kaiser FJ.
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| Am J Hum Genet 90(6):1014-27. Epub 2012 May 24.
2012
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| 15 | NSMCE2, RAD21, SMC3, WAPL
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| Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl.
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| Wu N, Kong X, Ji Z, Zeng W, Potts PR, Yokomori K, Yu H.
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| Genes Dev 26(13):1473-85. doi: 10.1101/gad.193615.112.
2012
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| 16 | RAD21, RAD21L1
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| A new meiosis-specific cohesin complex implicated in the cohesin code for homologous pairing.
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| Ishiguro K, Kim J, Fujiyama-Nakamura S, Kato S, Watanabe Y.
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| EMBO Rep 12(3):267-75. Epub 2011 Jan 28.
2011
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| 17 | RAD21, RAD21L1
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| Identification and molecular characterization of the mammalian α-kleisin RAD21L.
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| Gutiérrez-Caballero C, Herrán Y, Sánchez-Martín M, Suja JA, Barbero JL, Llano E, Pendás AM.
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| Cell Cycle 10(9):1477-87. Epub 2011 May 1. 2011
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| 18 | CAPN1, RAD21
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| Calpain-1 cleaves Rad21 to promote sister chromatid separation.
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| Panigrahi AK, Zhang N, Mao Q, Pati D.
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| Mol Cell Biol 31(21):4335-47. doi: 10.1128/MCB.06075-11. Epub 2011 Aug 29. 2011
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| 19 | RAD21, SMC1A, SMC3, STAG1
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| Cohesin: a regulator of genome integrity and gene expression.
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| Feeney KM, Wasson CW, Parish JL.
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| Biochem J 428(2):147-61. Review.PMID: 20462401 2010
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| 20 | RAD21
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| Cut1/separase-dependent roles of multiple phosphorylation of fission yeast cohesion subunit Rad21 in post-replicative damage repair and mitosis.
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| Adachi Y, Kokubu A, Ebe M, Nagao K, Yanagida M.
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| Cell Cycle 7(6):765-76. Epub 2007 Dec 29.PMID: 18239448 2008
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| 21 | RAD21
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| Correlation of invasion and metastasis of cancer cells, and expression of the RAD21 gene in oral squamous cell carcinoma.
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| Yamamoto G, Irie T, Aida T, Nagoshi Y, Tsuchiya R, Tachikawa T.
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| Virchows Arch 448(4):435-41. Epub 2006 Jan 14.PMID: 16416296 2006
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| 22 | RAD21, WASHC5
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| RAD21 and KIAA0196 at 8q24 are amplified and overexpressed in prostate cancer.
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| Porkka KP, Tammela TL, Vessella RL, Visakorpi T.
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| Genes Chromosomes Cancer 39(1):1-10. 2004
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| 23 | RAD21, SMARCA5
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| A chromatin remodelling complex that loads cohesin onto human chromosomes.
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| Hakimi MA, Bochar DA, Schmiesing JA, Dong Y, Barak OG, Speicher DW, Yokomori K, Shiekhattar R.
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| Nature 418(6901):994-8. 2002
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| 24 | RAD21
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| Cohesin defects lead to premature sister chromatid separation, kinetochore dysfunction, and spindle-assembly checkpoint activation.
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| Hoque MT, Ishikawa F.
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| J Biol Chem 277(44):42306-14. 2002
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| 25 | RAD21
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| Caspase proteolysis of the cohesin component RAD21 promotes apoptosis.
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| Chen F, Kamradt M, Mulcahy M, Byun Y, Xu H, McKay MJ, Cryns VL.
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| J Biol Chem 277(19):16775-81. 2002
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| 26 | RAD21
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| Linking sister chromatid cohesion and apoptosis: role of Rad21.
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| Pati D, Zhang N, Plon SE.
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| Mol Cell Biol 22(23):8267-77. 2002
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| 27 | RAD21
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| Human rad21 gene, hHR21(SP), is downregulated by hypoxia in human tumor cells.
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| Sook Kim M, Hyen Baek J, Bae MK, Kim KW.
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| Biochem Biophys Res Commun 281(5):1106-12. 2001
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| 28 | RAD21
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| Cohesin cleavage by separase required for anaphase and cytokinesis in human cells.
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| Hauf S, Waizenegger IC, Peters JM.
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| Science 293(5533):1320-3. 2001
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| 29 | RAD21
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| Human chromatid cohesin component hRad21 is phosphorylated in M phase and associated with metaphase centromeres.
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| Hoque MT, Ishikawa F.
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| J Biol Chem 276(7):5059-67. Epub 2000 Nov 9.PMID: 11073952 2001
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| 30 | RAD21
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| Sequence conservation of the rad21 Schizosaccharomyces pombe DNA double-strand break repair gene in human and mouse.
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| McKay MJ, et al.
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| Genomics 36 : 305-315. 1996
|