Citations for
1BRCA1, E2F4, RAD17
Gain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expression.
Valenti F, Ganci F, Fontemaggi G, Sacconi A, Strano S, Blandino G, Di Agostino S.
Oncotarget 6(8):5547-66. 2015
2RAD17, USP20
Ubiquitin-specific peptidase 20 regulates Rad17 stability, checkpoint kinase 1 phosphorylation and DNA repair by homologous recombination.
Shanmugam I, Abbas M, Ayoub F, Mirabal S, Bsaili M, Caulder EK, Weinstock DM, Tomkinson AE, Hromas R, Shaheen M.
J Biol Chem 289(33):22739-48. doi: 10.1074/jbc.M114.550459. Epub 2014 Jun 12. 2014
3RAD17, RAD9A
Heat induction of a novel Rad9 variant from a cryptic translation initiation site reduces mitotic commitment.
Janes S, Schmidt U, Ashour Garrido K, Ney N, Concilio S, Zekri M, Caspari T.
J Cell Sci 125(Pt 19):4487-97. doi: 10.1242/jcs.104075. Epub 2012 Jul 13. 2012
4CHEK1, CLSPN, RAD17
Functional relationship between Claspin and Rad17.
Yoshimura A, Akita M, Hosono Y, Abe T, Kobayashi M, Yamamoto K, Tada S, Seki M, Enomoto T.
Biochem Biophys Res Commun 414(2):298-303. Epub 2011 Sep 14. 2011
5RAD17
Proteolysis of Rad17 by Cdh1/APC regulates checkpoint termination and recovery from genotoxic stress.
Zhang L, Park CH, Wu J, Kim H, Liu W, Fujita T, Balasubramani M, Schreiber EM, Wang XF, Wan Y.
EMBO J 29(10):1726-37. Epub 2010 Apr 27. 2010
6RAD17
Rad17 plays a central role in establishment of the interaction between TopBP1 and the Rad9-Hus1-Rad1 complex at stalled replication forks.
Lee J, Dunphy WG.
Mol Biol Cell 21(6):926-35. Epub 2010 Jan 28. 2010
7ATR, CDC5L, CHEK1, FANCD2, RAD17
Cdc5L interacts with ATR and is required for the S-phase cell-cycle checkpoint.
Zhang N, Kaur R, Akhter S, Legerski RJ.
EMBO Rep 10(9):1029-35. Epub 2009 Jul 24. 2009
8RAD17
The human homolog of fission yeast Rad17 is implicated in tumor growth.
Beretta GL, Gatti L, Cesare MD, Corna E, Tinelli S, Carenini N, Zunino F, Perego P.
Cancer Lett 266(2):194-202. Epub 2008 Apr 18. 2008
9RAD17
Downregulation of RAD17 in head and neck cancer.
Zhao M, Begum S, Ha PK, Westra W, Califano J.
Head Neck 30(1):35-42. 2008
10RAD17
Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress.
Wang X, Zou L, Lu T, Bao S, Hurov KE, Hittelman WN, Elledge SJ, Li L.
Mol Cell 23(3):331-41. 2006
11ATR, RAD1, RAD17
Function of Rad17/Mec3/Ddc1 and its partial complexes in the DNA damage checkpoint.
Majka J, Burgers PM.
DNA Repair (Amst) 4(10):1189-94. 2005
12MCM7, RAD17
Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling.
Tsao CC, Geisen C, Abraham RT.
EMBO J 23(23):4660-9. Epub 2004 Nov 11. 2004
13RAD17
Multiple alternative splicing forms of human RAD17 and their differential response to ionizing radiation.
Chen MS, Higashikubo R, Laszlo A, Roti Roti J.
Gene 277(1-2):145-52. 2001
14RAD17
ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses.
Bao S, Tibbetts RS, Brumbaugh KM, Fang Y, Richardson DA, Ali A, Chen SM, Abraham RT, Wang XF.
Nature 411(6840):969-74. 2001
15RAD17
Human and mouse homologs of the schizosaccharomyces pombe rad17(+) cell cycle checkpoint control gene.
Bluyssen HAR, et al.
Genomics 55(2):219-28. 1999
16RAD17
HRad17, a human homologue of the Schizosaccharomyces pombe checkpoint gene rad17, is overexpressed in colon carcinoma.
Bao S, et al.
Cancer Res 59(9):2023-8. 1999
17RAD17, RAD17P1, RAD17P2
Human and mouse RAD17 genes: identification, localization, genomic structure and histological expression pattern in normal testis and seminoma.
von Deimling F, et al.
Hum Genet 105(1-2):17-27. 1999
18RAD17
hRAD17, a structural homolog of the Schizosaccharomyces pombe RAD17 cell cycle checkpoint gene, stimulates p53 accumulation.
Li L, Peterson CA, Kanter-Smoler G, Wei YF, Ramagli LS, Sunnerhagen P, Siciliano MJ, Legerski RJ.
Oncogene 18(9):1689-99. 1999
19RAD17
Identification of a human homologue of the Schizosaccharomyces pombe rad17+ checkpoint gene.
Parker AE, et al.
J Biol Chem 273 : 18340-18346. 1998
20HUS1, RAD1, RAD17
cDNA cloning and gene mapping of human homologs for Schizosaccharomyces pombe rad17, rad1, and hus1 and cloning of homologs from mouse, Caenorhabditis elegans, and Drosophila melanogaster.
Dean FB, et al.
Genomics 54 : 424-436. 1998
21RAD17
The mammalian Rad24 homologous to yeast Saccharomyces cerevisiae Rad24 and Schizosaccharomyces pombe Rad17 is involved in DNA damage checkpoint.
Bao S, Shen X, Shen K, Liu Y, Wang XF.
Cell Growth Differ 9(12):961-7. 1998
22RAD17
DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe.
al-Khodairy F, Carr AM.
EMBO J 11(4):1343-50. 1992