1 | BRCA1, E2F4, RAD17
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| Gain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expression.
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| Valenti F, Ganci F, Fontemaggi G, Sacconi A, Strano S, Blandino G, Di Agostino S.
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| Oncotarget 6(8):5547-66.
2015
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2 | RAD17, USP20
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| Ubiquitin-specific peptidase 20 regulates Rad17 stability, checkpoint kinase 1 phosphorylation and DNA repair by homologous recombination.
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| Shanmugam I, Abbas M, Ayoub F, Mirabal S, Bsaili M, Caulder EK, Weinstock DM, Tomkinson AE, Hromas R, Shaheen M.
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| J Biol Chem 289(33):22739-48. doi: 10.1074/jbc.M114.550459. Epub 2014 Jun 12.
2014
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3 | RAD17, RAD9A
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| Heat induction of a novel Rad9 variant from a cryptic translation initiation site reduces mitotic commitment.
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| Janes S, Schmidt U, Ashour Garrido K, Ney N, Concilio S, Zekri M, Caspari T.
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| J Cell Sci 125(Pt 19):4487-97. doi: 10.1242/jcs.104075. Epub 2012 Jul 13.
2012
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4 | CHEK1, CLSPN, RAD17
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| Functional relationship between Claspin and Rad17.
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| Yoshimura A, Akita M, Hosono Y, Abe T, Kobayashi M, Yamamoto K, Tada S, Seki M, Enomoto T.
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| Biochem Biophys Res Commun 414(2):298-303. Epub 2011 Sep 14.
2011
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5 | RAD17
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| Proteolysis of Rad17 by Cdh1/APC regulates checkpoint termination and recovery from genotoxic stress.
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| Zhang L, Park CH, Wu J, Kim H, Liu W, Fujita T, Balasubramani M, Schreiber EM, Wang XF, Wan Y.
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| EMBO J 29(10):1726-37. Epub 2010 Apr 27.
2010
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6 | RAD17
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| Rad17 plays a central role in establishment of the interaction between TopBP1 and the Rad9-Hus1-Rad1 complex at stalled replication forks.
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| Lee J, Dunphy WG.
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| Mol Biol Cell 21(6):926-35. Epub 2010 Jan 28.
2010
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7 | ATR, CDC5L, CHEK1, FANCD2, RAD17
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| Cdc5L interacts with ATR and is required for the S-phase cell-cycle checkpoint.
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| Zhang N, Kaur R, Akhter S, Legerski RJ.
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| EMBO Rep 10(9):1029-35. Epub 2009 Jul 24.
2009
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8 | RAD17
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| The human homolog of fission yeast Rad17 is implicated in tumor growth.
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| Beretta GL, Gatti L, Cesare MD, Corna E, Tinelli S, Carenini N, Zunino F, Perego P.
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| Cancer Lett 266(2):194-202. Epub 2008 Apr 18.
2008
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9 | RAD17
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| Downregulation of RAD17 in head and neck cancer.
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| Zhao M, Begum S, Ha PK, Westra W, Califano J.
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| Head Neck 30(1):35-42.
2008
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10 | RAD17
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| Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress.
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| Wang X, Zou L, Lu T, Bao S, Hurov KE, Hittelman WN, Elledge SJ, Li L.
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| Mol Cell 23(3):331-41.
2006
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11 | ATR, RAD1, RAD17
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| Function of Rad17/Mec3/Ddc1 and its partial complexes in the DNA damage checkpoint.
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| Majka J, Burgers PM.
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| DNA Repair (Amst) 4(10):1189-94.
2005
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12 | MCM7, RAD17
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| Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling.
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| Tsao CC, Geisen C, Abraham RT.
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| EMBO J 23(23):4660-9. Epub 2004 Nov 11.
2004
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13 | RAD17
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| Multiple alternative splicing forms of human RAD17 and their differential response to ionizing radiation.
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| Chen MS, Higashikubo R, Laszlo A, Roti Roti J.
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| Gene 277(1-2):145-52. 2001
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14 | RAD17
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| ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses.
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| Bao S, Tibbetts RS, Brumbaugh KM, Fang Y, Richardson DA, Ali A, Chen SM, Abraham RT, Wang XF.
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| Nature 411(6840):969-74. 2001
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15 | RAD17
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| Human and mouse homologs of the schizosaccharomyces pombe rad17(+) cell cycle checkpoint control gene.
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| Bluyssen HAR, et al.
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| Genomics 55(2):219-28. 1999
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16 | RAD17
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| HRad17, a human homologue of the Schizosaccharomyces pombe checkpoint gene rad17, is overexpressed in colon carcinoma.
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| Bao S, et al.
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| Cancer Res 59(9):2023-8. 1999
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17 | RAD17, RAD17P1, RAD17P2
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| Human and mouse RAD17 genes: identification, localization, genomic structure and histological expression pattern in normal testis and seminoma.
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| von Deimling F, et al.
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| Hum Genet 105(1-2):17-27. 1999
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18 | RAD17
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| hRAD17, a structural homolog of the Schizosaccharomyces pombe RAD17 cell cycle checkpoint gene, stimulates p53 accumulation.
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| Li L, Peterson CA, Kanter-Smoler G, Wei YF, Ramagli LS, Sunnerhagen P, Siciliano MJ, Legerski RJ.
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| Oncogene 18(9):1689-99. 1999
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19 | RAD17
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| Identification of a human homologue of the Schizosaccharomyces pombe rad17+ checkpoint gene.
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| Parker AE, et al.
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| J Biol Chem 273 : 18340-18346. 1998
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20 | HUS1, RAD1, RAD17
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| cDNA cloning and gene mapping of human homologs for Schizosaccharomyces pombe rad17, rad1, and hus1 and cloning of homologs from mouse, Caenorhabditis elegans, and Drosophila melanogaster.
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| Dean FB, et al.
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| Genomics 54 : 424-436. 1998
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21 | RAD17
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| The mammalian Rad24 homologous to yeast Saccharomyces cerevisiae Rad24 and Schizosaccharomyces pombe Rad17 is involved in DNA damage checkpoint.
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| Bao S, Shen X, Shen K, Liu Y, Wang XF.
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| Cell Growth Differ 9(12):961-7. 1998
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22 | RAD17
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| DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe.
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| al-Khodairy F, Carr AM.
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| EMBO J 11(4):1343-50. 1992
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