Citations for
1AAMDC, RAB7A, RABGAP1L
. The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer
Golden E, Rashwan R, Woodward EA, Sgro A, Wang E, Sorolla A, Waryah C, Tie WJ, Cuyàs E, Ratajska M, Kardaś I, Kozlowski P, Johnstone EKM, See HB, Duffy C, Parry J, Lagerborg KA, Czapiewski P, Menendez JA, Gorczyński A, Wasag B, Pfleger KDG, Curtis C, Lee BK, Kim J, Cursons J, Pavlos NJ, Biernat W, Jain M, Woo AJ, Redfern A, Blancafort P
Nat Commun. Mar 26;12(1):1920. doi: 10.1038/s41467-021-22101-7. 2021
2NDFIP1, NTRK02, RAB7A
Ubiquitin Regulation of Trk Receptor Trafficking and Degradation.
Murray SS, Wong AW, Yang J, Li Y, Putz U, Tan SS, Howitt J.
Mol Neurobiol ol Neurobiol. 2018 Jun 18. doi: 10.1007/s12035-018-1179-5. [Epub ahead of print] 2018
3RAB7A, TBC1D5
Inhibition of TBC1D5 activates Rab7a and can enhance the function of the retromer cargo-selective complex
Seaman MNJ, Mukadam AS, Breusegem SY.
J Cell Sci. Jun 21;131(12):jcs217398. doi: 10.1242/jcs.217398 2018
4ERBB2, NUMB, NUMBL, RAB7A
Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation.
Hirai M, Arita Y, McGlade CJ, Lee KF, Chen J, Evans SM.
J Clin Invest 127(2):569-582. doi: 10.1172/JCI91081. Epub 2017 Jan 9. 2017
5ARL8B, PLEKHM1, RAB7A
The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes.
Marwaha R, Arya SB, Jagga D, Kaur H, Tuli A, Sharma M.
J Cell Biol 216(4):1051-1070. doi: 10.1083/jcb.201607085. Epub 2017 Mar 21. 2017
6RAB7A, TBC1D15, TBC1D17
Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy.
Yamano K, Fogel AI, Wang C, van der Bliek AM, Youle RJ.
Elife 3:e01612. doi: 10.7554/eLife.01612. 2014
7RAB35, RAB7A
The role of the hypervariable C-terminal domain in Rab GTPases membrane targeting.
Li F, Yi L, Zhao L, Itzen A, Goody RS, Wu YW.
Proc Natl Acad Sci U S A 111(7):2572-7. doi: 10.1073/pnas.1313655111. Epub 2014 Feb 3. 2014
8CMT2B, RAB7A
Rab7 mutants associated with Charcot-Marie-Tooth disease cause delayed growth factor receptor transport and altered endosomal and nuclear signaling.
BasuRay S, Mukherjee S, Romero EG, Seaman MN, Wandinger-Ness A.
J Biol Chem 288(2):1135-49. doi: 10.1074/jbc.M112.417766. Epub 2012 Nov 27. 2013
9RAB7A, TSG101
RAB7 and TSG101 are required for the constitutive recycling of unliganded EGFRs via distinct mechanisms.
Rush JS, Ceresa BP.
Mol Cell Endocrinol 381(1-2):188-97. doi: 10.1016/j.mce.2013.07.029. Epub 2013 Aug 7. 2013
10PLEKHF1, PLEKHF2, RAB7A
Lysosomal targeting of phafin1 mediated by Rab7 induces autophagosome formation.
Lin WJ, Yang CY, Li LL, Yi YH, Chen KW, Lin YC, Liu CC, Lin CH.
Biochem Biophys Res Commun 417(1):35-42. doi: 10.1016/j.bbrc.2011.11.043. Epub 2011 Nov 15. 2012
11ATP6AP1, RAB7A
V-ATPase subunit ATP6AP1 (Ac45) regulates osteoclast differentiation, extracellular acidification, lysosomal trafficking, and protease exocytosis in osteoclast-mediated bone resorption.
Yang DQ, Feng S, Chen W, Zhao H, Paulson C, Li YP.
J Bone Miner Res 27(8):1695-707. doi: 10.1002/jbmr.1623. 2012
12RAB7A, STX7
Syntaxin7 is required for lytic granule release from cytotoxic T lymphocytes.
Pattu V, Qu B, Marshall M, Becherer U, Junker C, Matti U, Schwarz EC, Krause E, Hoth M, Rettig J.
Traffic 12(7):890-901. doi: 10.1111/j.1600-0854.2011.01193.x. Epub 2011 Apr 21. 2011
13RAB7A, SFTPA1
Pulmonary surfactant protein A enhances endolysosomal trafficking in alveolar macrophages through regulation of Rab7.
Sender V, Moulakakis C, Stamme C.
J Immunol 186(4):2397-411. doi: 10.4049/jimmunol.1002446. Epub 2011 Jan 19. 2011
14CMT2B, RAB7A
Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation.
McCray BA, Skordalakes E, Taylor JP.
Hum Mol Genet 19(6):1033-47. Epub 2009 Dec 22.PMID: 20028791 2010
15RAB7A, RUBCN, UVRAG
Rubicon controls endosome maturation as a Rab7 effector.
Sun Q, Westphal W, Wong KN, Tan I, Zhong Q.
Proc Natl Acad Sci U S A 107(45):19338-43. Epub 2010 Oct 25. 2010
16FYCO1, MAP1LC3A, RAB7A
FYCO1: Linking autophagosomes to microtubule plus end-directing molecular motors.
Pankiv S, Johansen T.
Autophagy 6(4). [Epub ahead of print] 2010
17KDR, RAB5A, RAB7A
Rab GTPase regulation of VEGFR2 trafficking and signaling in endothelial cells.
Jopling HM, Odell AF, Hooper NM, Zachary IC, Walker JH, Ponnambalam S.
Arterioscler Thromb Vasc Biol 29(7):1119-24. Epub 2009 Apr 16. 2009
18RAB7A
Rab7: roles in membrane trafficking and disease.
Zhang M, Chen L, Wang S, Wang T.
Biosci Rep 29(3):193-209. Review. 2009
19RAB7A, RILP
Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning.
Rocha N, Kuijl C, van der Kant R, Janssen L, Houben D, Janssen H, Zwart W, Neefjes J.
J Cell Biol 185(7):1209-25. 2009
20RAB7A, CMT2B
Characterization of the Rab7K157N mutant protein associated with Charcot-Marie-Tooth type 2B.
De Luca A, Progida C, Spinosa MR, Alifano P, Bucci C.
Biochem Biophys Res Commun 372(2):283-7. Epub 2008 May 21. 2008
21CMT2B, RAB7A
Functional characterization of Rab7 mutant proteins associated with Charcot-Marie-Tooth type 2B disease.
Spinosa MR, Progida C, De Luca A, Colucci AM, Alifano P, Bucci C.
J Neurosci 28(7):1640-8. 2008
22PMEL, RAB7A
Rab7 regulates maturation of melanosomal matrix protein gp100/Pmel17/Silv.
Kawakami A, Sakane F, Imai S, Yasuda S, Kai M, Kanoh H, Jin HY, Hirosaki K, Yamashita T, Fisher DE, Jimbow K.
J Invest Dermatol 128(1):143-50. Epub 2007 Jul 12. 2008
23RAB7A, RILP, SNF8, VPS36
RILP is required for the proper morphology and function of late endosomes.
Progida C, Malerød L, Stuffers S, Brech A, Bucci C, Stenmark H.
J Cell Sci 120(Pt 21):3729-37. 2007
24RAB7A, RILP
Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrin.
Johansson M, Rocha N, Zwart W, Jordens I, Janssen L, Kuijl C, Olkkonen VM, Neefjes J.
J Cell Biol 176(4):459-71. Epub 2007 Feb 5. 2007
25CMT2B, RAB7A
Charcot-Marie-Tooth disease due to a de novo mutation of the RAB7 gene.
Meggouh F, Bienfait HM, Weterman MA, de Visser M, Baas F.
Neurology 67(8):1476-8. 2006
26RAB7A, RILP, SNF8
RILP interacts with the VPS22 component of the ESCRT-II complex.
Progida C, Spinosa MR, De Luca A, Bucci C.
Biochem Biophys Res Commun 347(4):1074-9. Epub 2006 Jul 12. 2006
27ATP7B, RAB7A, NPC1
The Wilson disease protein ATP7B resides in the late endosomes with Rab7 and the Niemann-Pick C1 protein.
Harada M, Kawaguchi T, Kumemura H, Terada K, Ninomiya H, Taniguchi E, Hanada S, Baba S, Maeyama M, Koga H, Ueno T, Furuta K, Suganuma T, Sugiyama T, Sata M.
Am J Pathol 166(2):499-510. 2005
28OSBPL1A, RAB7A
The oxysterol-binding protein homologue ORP1L interacts with Rab7 and alters functional properties of late endocytic compartments.
Johansson M, Lehto M, Tanhuanpaa K, Cover TL, Olkkonen VM.
Mol Biol Cell 16(12):5480-92. Epub 2005 Sep 21. 2005
29CMT2B, RAB7A
A novel RAB7 mutation associated with ulcero-mutilating neuropathy.
Houlden H, King RH, Muddle JR, Warner TT, Reilly MM, Orrell RW, Ginsberg L.
Ann Neurol 56(4):586-90. 2004
30CMT2B, RAB7A
Mutations in the small GTP-ase late endosomal protein RAB7 cause Charcot-Marie-Tooth type 2B neuropathy
Verhoeven K, De Jonghe P, Coen K, Verpoorten N, Auer-Grumbach M, Kwon JM, FitzPatrick D, Schmedding E, De Vriendt E, Jacobs A, Van Gerwen V, Wagner K, Hartung HP, Timmerman V.
Am J Hum Genet 72(3):722-7. 2003
31RAB15, RAB25, RAB34, RAB39A, RAB5A, RAB7A
Rab39, a novel Golgi-associated Rab GTPase from human dendritic cells involved in cellular endocytosis.
Chen T, Han Y, Yang M, Zhang W, Li N, Wan T, Guo J, Cao X.
Biochem Biophys Res Commun 303(4):1114-20. 2003
32RAB7A, ZNF364
Rabring7, a novel Rab7 target protein with a RING finger motif.
Mizuno K, Kitamura A, Sasaki T.
Mol Biol Cell 14(9):3741-52. Epub 2003 Jul 11. 2003
33RAB7A
Rab7 gene is up-regulated by cholesterol-rich diet in the liver and artery.
Kim JY, Jang MK, Lee SS, Choi MS, Bok SH, Oh GT, Park YB.
Biochem Biophys Res Commun 293(1):375-82. 2002
34RAB7A, RILP
Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes.
Cantalupo G, Alifano P, Roberti V, Bruni CB, Bucci C.
EMBO J 20(4):683-93. 2001
35RAB7A
Genetic mapping of the mouse Rab7 gene and pseudogene and of the human RAB7 homolog.
Chiariello M, et al.
Mamm Genome 9 : 448-452. 1998
36RAB1A, RAB4A, RAB5B, RAB7A, RAB8A, RAB13
Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects.
Bao S, et al.
Horm Metab Res 30(11):656-62. 1998
37USP7, RAB7A, TFRC
NotI linking/jumping clones of human chromosome 3 : mapping of the TFRC, RAB7 and HAUSP genes to regions rearranged in leukemia and deleted in solid tumors.
Kashuba VI, Gizatullin RZ, Protopopov AI, Allikmets R, Korolev S, Li J, Boldog F, Tory K, Zabarovska V, Marcsek Z, Sumegi J, Klein G, Zabarovsky ER, Kisselev L.
FEBS Lett 419(2-3):181-5. 1997
38RAB7A, RAB9P1, RAB9A
Cloning and mapping of human Rab7 and Rab9 cDNA sequences and identification of a Rab9 pseudogene.
Davies JP, Cotter PD, Ioannou YA.
Genomics 41(1):131-4. 1997