| 1 | DEL5Q31.3, PURA
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| Mutations in PURA Cause Profound Neonatal Hypotonia, Seizures, and Encephalopathy in 5q31.3 Microdeletion Syndrome.
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| Lalani SR, Zhang J, Schaaf CP, Brown CW, Magoulas P, Tsai AC, El-Gharbawy A, Wierenga KJ, Bartholomew D, Fong CT, Barbaro-Dieber T, Kukolich MK, Burrage LC, Austin E, Keller K, Pastore M, Fernandez F, Lotze T, Wilfong A, Purcarin G, Zhu W, Craigen WJ, McGuire M, Jain M, Cooney E, Azamian M, Bainbridge MN, Muzny DM, Boerwinkle E, Person RE, Niu Z, Eng CM, Lupski JR, Gibbs RA, Beaudet AL, Yang Y, Wang MC, Xia F.
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| Am J Hum Genet 95(5):579-83. doi: 10.1016/j.ajhg.2014.09.014. Epub 2014 Oct 16.
2014
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| 2 | MRD30, PURA
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| Whole exome sequencing in family trios reveals de novo mutations in PURA as a cause of severe neurodevelopmental delay and learning disability.
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| Hunt D, Leventer RJ, Simons C, Taft R, Swoboda KJ, Gawne-Cain M; DDD study, Magee AC, Turnpenny PD, Baralle D.
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| J Med Genet 51(12):806-13. doi: 10.1136/jmedgenet-2014-102798. Epub 2014 Oct 23.
2014
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| 3 | PURA
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| The pur protein family: genetic and structural features in development and disease.
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| Johnson EM, Daniel DC, Gordon J.
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| J Cell Physiol 228(5):930-7. doi: 10.1002/jcp.24237. Review.
2013
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| 4 | DEL5Q31.3, NRG2, PURA
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| Clinical phenotype and candidate genes for the 5q31.3 microdeletion syndrome.
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| Hosoki K, Ohta T, Natsume J, Imai S, Okumura A, Matsui T, Harada N, Bacino CA, Scaglia F, Jones JY, Niikawa N, Saitoh S.
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| Am J Med Genet A 158A(8):1891-6. doi: 10.1002/ajmg.a.35439. Epub 2012 Jun 18.
2012
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| 5 | PURA
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| Lack of Pur-alpha alters postnatal brain development and causes megalencephaly.
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| Hokkanen S, Feldmann HM, Ding H, Jung CK, Bojarski L, Renner-Müller I, Schüller U, Kretzschmar H, Wolf E, Herms J.
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| Hum Mol Genet 21(3):473-84. doi: 10.1093/hmg/ddr476. Epub 2011 Oct 18.
2012
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| 6 | PURA
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| Drosophila Pur-α binds to trinucleotide-repeat containing cellular RNAs and translocates to the early oocyte.
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| Aumiller V, Graebsch A, Kremmer E, Niessing D, Förstemann K.
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| RNA Biol 9(5):633-43. doi: 10.4161/rna.19760. Epub 2012 May 1.
2012
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| 7 | PURA, PURB
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| Isolation and characterization of the core single-stranded DNA-binding domain of purine-rich element binding protein B (Purβ).
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| Rumora AE, Steere AN, Ramsey JE, Knapp AM, Ballif BA, Kelm RJ Jr.
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| Biochem Biophys Res Commun 400(3):340-5. Epub 2010 Aug 20.
2010
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| 8 | PURA
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| Regulation of PURA gene transcription by three promoters generating distinctly spliced 5-prime leaders: a novel means of fine control over tissue specificity and viral signals.
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| Wortman MJ, Hanson LK, Martínez-Sobrido L, Campbell AE, Nance JA, García-Sastre A, Johnson EM.
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| BMC Mol Biol 11:81. doi: 10.1186/1471-2199-11-81.
2010
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| 9 | PURA
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| Role of Purα in the cellular response to ultraviolet-C radiation.
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| Kaminski R, Cheeseboro L, Amini S, Johnson EM, White MK, Khalili K, Darbinyan A.
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| Cell Cycle 9(20):4164-73. Epub 2010 Oct 27.
2010
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| 10 | PURA, PURB
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| Mechanism of strand-specific smooth muscle alpha-actin enhancer interaction by purine-rich element binding protein B (Purbeta).
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| Ramsey JE, Kelm RJ Jr.
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| Biochemistry 48(27):6348-60.
2009
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| 11 | PURA
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| Purine-rich element binding protein (PUR) alpha induces endoplasmic reticulum stress response, and cell differentiation pathways in prostate cancer cells.
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| Inoue T, Maeno A, Talbot C Jr, Zeng Y, Yeater DB, Leman ES, Kulkarni P, Ogawa O, Getzenberg RH.
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| Prostate 69(8):861-73. doi: 10.1002/pros.20936.
2009
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| 12 | PURA
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| Negative regulation of AbetaPP gene expression by pur-alpha.
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| Darbinian N, Cui J, Basile A, Del Valle L, Otte J, Miklossy J, Sawaya BE, Amini S, Khalili K, Gordon J.
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| J Alzheimers Dis 15(1):71-82.
2008
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| 13 | PURA
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| The potential role of purine-rich element binding protein (PUR) alpha as a novel treatment target for hormone-refractory prostate cancer.
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| Inoue T, Leman ES, Yeater DB, Getzenberg RH.
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| Prostate 68(10):1048-56.
2008
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| 14 | PURA, PURB
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| Serum response factor neutralizes Pur alpha- and Pur beta-mediated repression of the fetal vascular smooth muscle alpha-actin gene in stressed adult cardiomyocytes.
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| Zhang A, David JJ, Subramanian SV, Liu X, Fuerst MD, Zhao X, Leier CV, Orosz CG, Kelm RJ Jr, Strauch AR.
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| Am J Physiol Cell Physiol 294(3):C702-14. Epub 2008 Jan 9.
2008
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| 15 | PURA, PURB
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| Puralpha and Purbeta collaborate with Sp3 to negatively regulate beta-myosin heavy chain gene expression during skeletal muscle inactivity.
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| Ji J, Tsika GL, Rindt H, Schreiber KL, McCarthy JJ, Kelm RJ Jr, Tsika R.
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| Mol Cell Biol 27(4):1531-43. Epub 2006 Dec 4.
2007
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| 16 | PURA, PURB
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| Nucleoprotein interactions governing cell type-dependent repression of the mouse smooth muscle alpha-actin promoter by single-stranded DNA-binding proteins Pur alpha and Pur beta.
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| Knapp AM, Ramsey JE, Wang SX, Godburn KE, Strauch AR, Kelm RJ Jr.
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| J Biol Chem 281(12):7907-18. Epub 2006 Jan 25.
2006
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| 17 | CDK2, PURA
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| Functional interaction of Puralpha with the Cdk2 moiety of cyclin A/Cdk2.
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| Liu H, Barr SM, Chu C, Kohtz DS, Kinoshita Y, Johnson EM.
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| Biochem Biophys Res Commun 328(4):851-7.
2005
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| 18 | E2F1, PURA
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| Interaction between the pura and E2F-1 transcription factors.
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| Darbinian N, White MK, Gallia GL, Amini S, Rappaport J, Khalili K.
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| Anticancer Res 24(5A):2585-94.
2004
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| 19 | PURA
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| Puralpha is essential for postnatal brain development and developmentally coupled cellular proliferation as revealed by genetic inactivation in the mouse.
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| Khalili K, Del Valle L, Muralidharan V, Gault WJ, Darbinian N, Otte J, Meier E, Johnson EM, Daniel DC, Kinoshita Y, Amini S, Gordon J.
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| Mol Cell Biol 23(19):6857-75.
2003
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| 20 | PURA, PURB
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| Single-stranded DNA-binding proteins PURalpha and PURbeta bind to a purine-rich negative regulatory element of the alpha-myosin heavy chain gene and control transcriptional and translational regulation of the gene expression. Implications in the repression of alpha-myosin heavy chain during heart failure.
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| Gupta M, Sueblinvong V, Raman J, Jeevanandam V, Gupta MP.
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| J Biol Chem 278(45):44935-48. Epub 2003 Aug 21.
2003
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| 21 | PURA
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| Identification of mRNA/protein (mRNP) complexes containing Puralpha, mStaufen, fragile X protein, and myosin Va and their association with rough endoplasmic reticulum equipped with a kinesin motor.
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| Ohashi S, Koike K, Omori A, Ichinose S, Ohara S, Kobayashi S, Sato TA, Anzai K.
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| J Biol Chem 277(40):37804-10. Epub 2002 Jul 29. 2002
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| 22 | PURA
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| Localization of PURA, the gene encoding the sequence-specific single-stranded-DNA-binding protein Puralpha, to chromosome band 5q31.
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| Ma ZW, et al.
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| Cytogenet Cell Genet 71 : 64-67. 1995
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| 23 | PURA
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| The HeLa pur factor binds single-stranded DNA at a specific element conserved in gene flanking regions and origins of DNA replication.
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| Bergemann AD, et al.
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| Mol Cell Biol 12 : 1257-1265. 1992
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