Citations for
1PTPRN, RESP18
Biochemical, biophysical, and functional properties of ICA512/IA-2 RESP18 homology domain.
Sosa L, Torkko JM, Primo ME, Llovera RE, Toledo PL, Rios AS, Flecha FL, Trabucchi A, Valdez SN, Poskus E, Solimena M, Ermácora MR.
Biochim Biophys Acta 1864(5):511-22. doi: 10.1016/j.bbapap.2016.01.013. Epub 2016 Feb 1. 2016
2PTPRN
The minimal promoter region of the dense-core vesicle protein IA-2: transcriptional regulation by CREB.
Cai T, Hirai H, Xu H, Notkins AL.
Acta Diabetol 52(3):573-80. doi: 10.1007/s00592-014-0689-5. Epub 2014 Dec 21. 2015
3PTPRN
The dense core vesicle protein IA-2, but not IA-2β, is required for active avoidance learning.
Carmona GN, Nishimura T, Schindler CW, Panlilio LV, Notkins AL.
Neuroscience 269:35-42. doi: 10.1016/j.neuroscience.2014.03.023. Epub 2014 Mar 21. 2014
4PTPRN, PTPRN2
Immunohistochemical analysis of IA-2 family of protein tyrosine phosphatases in rat gastrointestinal endocrine cells.
Gomi H, Kubota-Murata C, Yasui T, Tsukise A, Torii S.
J Histochem Cytochem 61(2):156-68. doi: 10.1369/0022155412466872. Epub 2012 Oct 18. 2013
5PTPRN
Protein-protein interactions in crystals of the human receptor-type protein tyrosine phosphatase ICA512 ectodomain.
Primo ME, Jakoncic J, Noguera ME, Risso VA, Sosa L, Sica MP, Solimena M, Poskus E, Ermácora MR.
PLoS One 6(9):e24191. doi: 10.1371/journal.pone.0024191. Epub 2011 Sep 15. 2011
6PTPRN, PTPRN2
The neurosecretory vesicle protein phogrin functions as a phosphatidylinositol phosphatase to regulate insulin secretion.
Caromile LA, Oganesian A, Coats SA, Seifert RA, Bowen-Pope DF.
J Biol Chem 285(14):10487-96. Epub 2010 Jan 22. 2010
7PTPRN, PTPRN2
The insulin secretory granule as a signaling hub.
Suckale J, Solimena M.
Trends Endocrinol Metab rends Endocrinol Metab. 2010 Jul 5. [Epub ahead of print]PMID: 20609596 2010
8PTPRN2, PTPRn
Deletion of the secretory vesicle proteins IA-2 and IA-2beta disrupts circadian rhythms of cardiovascular and physical activity.
Kim SM, Power A, Brown TM, Constance CM, Coon SL, Nishimura T, Hirai H, Cai T, Eisner C, Weaver DR, Piggins HD, Klein DC, Schnermann J, Notkins AL.
FASEB J 23(9):3226-32. doi: 10.1096/fj.09-132019. Epub 2009 May 11. 2009
9IRS2, PTPRN, PTPRN2
Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growth.
Torii S, Saito N, Kawano A, Hou N, Ueki K, Kulkarni RN, Takeuchi T.
Diabetes 58(3):682-92. doi: 10.2337/db08-0970. Epub 2008 Dec 10. 2009
10PTPRN
ICA512 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATs.
Mziaut H, Kersting S, Knoch KP, Fan WH, Trajkovski M, Erdmann K, Bergert H, Ehehalt F, Saeger HD, Solimena M.
Proc Natl Acad Sci U S A 105(2):674-9. Epub 2008 Jan 4. 2008
11PTPRN, SNTB2
Regulation of insulin granule turnover in pancreatic beta-cells by cleaved ICA512.
Trajkovski M, Mziaut H, Schubert S, Kalaidzidis Y, Altkrüger A, Solimena M.
J Biol Chem 283(48):33719-29. doi: 10.1074/jbc.M804928200. Epub 2008 Sep 29. 2008
12PTPRN, RESP18
RESP18, a homolog of the luminal domain IA-2, is found in dense core vesicles in pancreatic islet cells and is induced by high glucose.
Zhang G, Hirai H, Cai T, Miura J, Yu P, Huang H, Schiller MR, Swaim WD, Leapman RD, Notkins AL.
J Endocrinol 195(2):313-21.PMID: 17951542 2007
13AGPAT6, AGTPBP1, AJUBA, BATF2, BEND2, CCDC107, CELF2, CSTF2, ECM1, EFEMP1, FAM127A, ITGB4, KIF17, LTBP4, NELF, NETS, NPHP1, PCDRS, PEG3, PELI2, PTPRN, PTPRN2, RAD54L2, RBFOX1, RBFOX2, RBPMS, RHOXF1, SCAMP1, SPINK5, TAF9, THAP1, TTC19, UBE2E3, UCHL3, WDYHV1, ZFPM2, ZNF488
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
Lim J, Hao T, Shaw C, Patel AJ, Szabo G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabasi AL, Vidal M, Zoghbi HY.
Cell 125(4):801-14. 2006
14PTPRN
Genomic structure of mouse IA-2: comparison with its human homologue.
Saeki K, Xie J, Notkins AL.
Diabetologia 43(11):1429-34. 2000
15PTPRN, PTPRN2
Localization of the genes encoding the type I diabetes autoantigens, protein-tyrosine phosphatases IA2 and IAR.
Morahan G, Huang D, Yu WP, Cui L, DeAizpurua H, Pallen CJ.
Mamm Genome 9 : 593-594. 1998
16PTPRN
Genomic structure and promoter sequence of the insulin-dependent diabetes mellitus autoantigen, IA-2 (PTPRN).
Xie J, et al.
Genomics 54 : 338-343. 1998
17PTPRN, PTPRN2
Mapping to chromosomes 1 and 12 of mouse homologs of human protein tyrosine phosphatase, receptor-type, related genes encoding pancreatic beta cell autoantigens.
Leiter EH, Tsumura H, Serreze DV, Chapman HD, Rabin DU, Lan MS, Notkins AL.
Mamm Genome 8(12):949-50. 1997
18PTPRN
Assignment of the human gene for receptor-type protein tyrosine phosphatase IA-2 (PTPRN) to chromosome region 2q35-q36.1 and identification of an intragenic genetic marker.
van den Maagdenberg AMJM, et al.
Cytogenet Cell Genet 73 : 145-148. 1996
19PTPRN
Assignment of the IA-2 gene encoding an autoantigen in IDDM to chromosome 2q35.
Lan MS, et al.
Diabetologia 39 : 1001-1003. 1996
20PTPRN
Cloning and characterization of islet cell antigen-related protein-tyrosine phosphatase (PTP), a novel receptor-like PTP and autoantigen in insulin-dependent diabetes.
Cui L, Yu WP, DeAizpurua HJ, Schmidli RS, Pallen CJ.
J Biol Chem 271 : 24817-24823. 1996
21PTPRN
Molecular cloning and identification of a receptor-type protein tyrosine phosphatase, IA-2, from human insulinoma.
Lan MS, et al.
DNA Cell Biol 13 : 505-514. 1994