| 1 | PTPRN, RESP18
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| Biochemical, biophysical, and functional properties of ICA512/IA-2 RESP18 homology domain.
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| Sosa L, Torkko JM, Primo ME, Llovera RE, Toledo PL, Rios AS, Flecha FL, Trabucchi A, Valdez SN, Poskus E, Solimena M, Ermácora MR.
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| Biochim Biophys Acta 1864(5):511-22. doi: 10.1016/j.bbapap.2016.01.013. Epub 2016 Feb 1.
2016
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| 2 | PTPRN
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| The minimal promoter region of the dense-core vesicle protein IA-2: transcriptional regulation by CREB.
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| Cai T, Hirai H, Xu H, Notkins AL.
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| Acta Diabetol 52(3):573-80. doi: 10.1007/s00592-014-0689-5. Epub 2014 Dec 21.
2015
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| 3 | PTPRN
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| The dense core vesicle protein IA-2, but not IA-2β, is required for active avoidance learning.
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| Carmona GN, Nishimura T, Schindler CW, Panlilio LV, Notkins AL.
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| Neuroscience 269:35-42. doi: 10.1016/j.neuroscience.2014.03.023. Epub 2014 Mar 21.
2014
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| 4 | PTPRN, PTPRN2
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| Immunohistochemical analysis of IA-2 family of protein tyrosine phosphatases in rat gastrointestinal endocrine cells.
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| Gomi H, Kubota-Murata C, Yasui T, Tsukise A, Torii S.
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| J Histochem Cytochem 61(2):156-68. doi: 10.1369/0022155412466872. Epub 2012 Oct 18.
2013
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| 5 | PTPRN
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| Protein-protein interactions in crystals of the human receptor-type protein tyrosine phosphatase ICA512 ectodomain.
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| Primo ME, Jakoncic J, Noguera ME, Risso VA, Sosa L, Sica MP, Solimena M, Poskus E, Ermácora MR.
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| PLoS One 6(9):e24191. doi: 10.1371/journal.pone.0024191. Epub 2011 Sep 15.
2011
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| 6 | PTPRN, PTPRN2
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| The neurosecretory vesicle protein phogrin functions as a phosphatidylinositol phosphatase to regulate insulin secretion.
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| Caromile LA, Oganesian A, Coats SA, Seifert RA, Bowen-Pope DF.
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| J Biol Chem 285(14):10487-96. Epub 2010 Jan 22. 2010
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| 7 | PTPRN, PTPRN2
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| The insulin secretory granule as a signaling hub.
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| Suckale J, Solimena M.
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| Trends Endocrinol Metab rends Endocrinol Metab. 2010 Jul 5. [Epub ahead of print]PMID: 20609596 2010
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| 8 | PTPRN2, PTPRn
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| Deletion of the secretory vesicle proteins IA-2 and IA-2beta disrupts circadian rhythms of cardiovascular and physical activity.
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| Kim SM, Power A, Brown TM, Constance CM, Coon SL, Nishimura T, Hirai H, Cai T, Eisner C, Weaver DR, Piggins HD, Klein DC, Schnermann J, Notkins AL.
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| FASEB J 23(9):3226-32. doi: 10.1096/fj.09-132019. Epub 2009 May 11.
2009
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| 9 | IRS2, PTPRN, PTPRN2
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| Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growth.
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| Torii S, Saito N, Kawano A, Hou N, Ueki K, Kulkarni RN, Takeuchi T.
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| Diabetes 58(3):682-92. doi: 10.2337/db08-0970. Epub 2008 Dec 10.
2009
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| 10 | PTPRN
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| ICA512 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATs.
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| Mziaut H, Kersting S, Knoch KP, Fan WH, Trajkovski M, Erdmann K, Bergert H, Ehehalt F, Saeger HD, Solimena M.
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| Proc Natl Acad Sci U S A 105(2):674-9. Epub 2008 Jan 4. 2008
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| 11 | PTPRN, SNTB2
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| Regulation of insulin granule turnover in pancreatic beta-cells by cleaved ICA512.
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| Trajkovski M, Mziaut H, Schubert S, Kalaidzidis Y, Altkrüger A, Solimena M.
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| J Biol Chem 283(48):33719-29. doi: 10.1074/jbc.M804928200. Epub 2008 Sep 29.
2008
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| 12 | PTPRN, RESP18
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| RESP18, a homolog of the luminal domain IA-2, is found in dense core vesicles in pancreatic islet cells and is induced by high glucose.
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| Zhang G, Hirai H, Cai T, Miura J, Yu P, Huang H, Schiller MR, Swaim WD, Leapman RD, Notkins AL.
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| J Endocrinol 195(2):313-21.PMID: 17951542 2007
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| 13 | AGPAT6, AGTPBP1, AJUBA, BATF2, BEND2, CCDC107, CELF2, CSTF2, ECM1, EFEMP1, FAM127A, ITGB4, KIF17, LTBP4, NELF, NETS, NPHP1, PCDRS, PEG3, PELI2, PTPRN, PTPRN2, RAD54L2, RBFOX1, RBFOX2, RBPMS, RHOXF1, SCAMP1, SPINK5, TAF9, THAP1, TTC19, UBE2E3, UCHL3, WDYHV1, ZFPM2, ZNF488
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| A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
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| Lim J, Hao T, Shaw C, Patel AJ, Szabo G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabasi AL, Vidal M, Zoghbi HY.
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| Cell 125(4):801-14. 2006
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| 14 | PTPRN
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| Genomic structure of mouse IA-2: comparison with its human homologue.
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| Saeki K, Xie J, Notkins AL.
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| Diabetologia 43(11):1429-34. 2000
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| 15 | PTPRN, PTPRN2
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| Localization of the genes encoding the type I diabetes autoantigens, protein-tyrosine phosphatases IA2 and IAR.
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| Morahan G, Huang D, Yu WP, Cui L, DeAizpurua H, Pallen CJ.
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| Mamm Genome 9 : 593-594. 1998
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| 16 | PTPRN
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| Genomic structure and promoter sequence of the insulin-dependent diabetes mellitus autoantigen, IA-2 (PTPRN).
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| Xie J, et al.
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| Genomics 54 : 338-343. 1998
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| 17 | PTPRN, PTPRN2
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| Mapping to chromosomes 1 and 12 of mouse homologs of human protein tyrosine phosphatase, receptor-type, related genes encoding pancreatic beta cell autoantigens.
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| Leiter EH, Tsumura H, Serreze DV, Chapman HD, Rabin DU, Lan MS, Notkins AL.
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| Mamm Genome 8(12):949-50. 1997
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| 18 | PTPRN
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| Assignment of the human gene for receptor-type protein tyrosine phosphatase IA-2 (PTPRN) to chromosome region 2q35-q36.1 and identification of an intragenic genetic marker.
|
| van den Maagdenberg AMJM, et al.
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| Cytogenet Cell Genet 73 : 145-148. 1996
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| 19 | PTPRN
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| Assignment of the IA-2 gene encoding an autoantigen in IDDM to chromosome 2q35.
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| Lan MS, et al.
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| Diabetologia 39 : 1001-1003. 1996
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| 20 | PTPRN
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| Cloning and characterization of islet cell antigen-related protein-tyrosine phosphatase (PTP), a novel receptor-like PTP and autoantigen in insulin-dependent diabetes.
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| Cui L, Yu WP, DeAizpurua HJ, Schmidli RS, Pallen CJ.
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| J Biol Chem 271 : 24817-24823. 1996
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| 21 | PTPRN
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| Molecular cloning and identification of a receptor-type protein tyrosine phosphatase, IA-2, from human insulinoma.
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| Lan MS, et al.
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| DNA Cell Biol 13 : 505-514. 1994
|