| 1 | PTPRA, RACK1
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| The interaction of protein-tyrosine phosphatase α (PTPα) and RACK1 protein enables insulin-like growth factor 1 (IGF-1)-stimulated Abl-dependent and -independent tyrosine phosphorylation of PTPα.
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| Khanna RS, Le HT, Wang J, Fung TC, Pallen CJ.
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| J Biol Chem 290(15):9886-95. doi: 10.1074/jbc.M114.624247. 2015
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| 2 | PTPRA
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| RPTPα controls epithelial adherens junctions, linking E-cadherin engagement to c-Src-mediated phosphorylation of cortactin.
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| Truffi M, Dubreuil V, Liang X, Vacaresse N, Nigon F, Han SP, Yap AS, Gomez GA, Sap J.
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| J Cell Sci 127(Pt 11):2420-32. doi: 10.1242/jcs.134379.
2014
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| 3 | GRB2, PTK2, PTPRA
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| Grb2 promotes integrin-induced focal adhesion kinase (FAK) autophosphorylation and directs the phosphorylation of protein tyrosine phosphatase α by the Src-FAK kinase complex.
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| Cheng SY, Sun G, Schlaepfer DD, Pallen CJ.
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| Mol Cell Biol 34(3):348-61. doi: 10.1128/MCB.00825-13.
2014
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| 4 | PTPRA
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| Protein tyrosine phosphatase α mediates profibrotic signaling in lung fibroblasts through TGF-β responsiveness.
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| Aschner Y, Khalifah AP, Briones N, Yamashita C, Dolgonos L, Young SK, Campbell MN, Riches DW, Redente EF, Janssen WJ, Henson PM, Sap J, Vacaresse N, Kapus A, McCulloch CA, Zemans RL, Downey GP.
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| Am J Pathol 184(5):1489-502. doi: 10.1016/j.ajpath.2014.01.016.
2014
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| 5 | PTPRA
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| Abnormal myelination in the spinal cord of PTPα-knockout mice.
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| Ma QH, Xiang T, Yang ZZ, Zhang X, Taylor J, Xiao ZC.
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| Cell Adh Migr 7(4):370-6. doi: 10.4161/cam.25652.
2013
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| 6 | BCAR3, PTPRA
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| Protein tyrosine phosphatase α phosphotyrosyl-789 binds BCAR3 to position Cas for activation at integrin-mediated focal adhesions.
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| Sun G, Cheng SY, Chen M, Lim CJ, Pallen CJ.
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| Mol Cell Biol 32(18):3776-89. doi: 10.1128/MCB.00214-12.
2012
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| 7 | PTPRA
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| Loss of protein-tyrosine phosphatase α (PTPα) increases proliferation and delays maturation of oligodendrocyte progenitor cells.
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| Wang PS, Wang J, Zheng Y, Pallen CJ.
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| J Biol Chem 287(15):12529-40. doi: 10.1074/jbc.M111.312769.
2012
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| 8 | PTPRA
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| Activation of Src and transformation by an RPTPα splice mutant found in human tumours.
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| Huang J, Yao L, Xu R, Wu H, Wang M, White BS, Shalloway D, Zheng X.
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| EMBO J 30(15):3200-11. doi: 10.1038/emboj.2011.212. 2011
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| 9 | PTPRA
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| Serine dephosphorylation of receptor protein tyrosine phosphatase alpha in mitosis induces Src binding and activation.
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| Vacaru AM, den Hertog J.
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| Mol Cell Biol 30(12):2850-61. Epub 2010 Apr 12.
2010
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| 10 | PTPRA
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| Extracellular domain dependence of PTPalpha transforming activity.
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| Tremper-Wells B, Resnick RJ, Zheng X, Holsinger LJ, Shalloway D.
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| Genes Cells 15(7):711-24. doi: 10.1111/j.1365-2443.2010.01410.x.
2010
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| 11 | FYN, PTPRA
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| Protein-tyrosine phosphatase alpha acts as an upstream regulator of Fyn signaling to promote oligodendrocyte differentiation and myelination.
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| Wang PS, Wang J, Xiao ZC, Pallen CJ.
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| J Biol Chem 284(48):33692-702. doi: 10.1074/jbc.M109.061770.
2009
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| 12 | CD63, KCNJ1, PTPRA, SRC
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| Expression of tetraspan protein CD63 activates protein-tyrosine kinase (PTK) and enhances the PTK-induced inhibition of ROMK channels.
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| Lin D, Kamsteeg EJ, Zhang Y, Jin Y, Sterling H, Yue P, Roos M, Duffield A, Spencer J, Caplan M, Wang WH.
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| J Biol Chem 283(12):7674-81. Epub 2008 Jan 22. 2008
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| 13 | PTPRA
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| Activation of c-Src and Fyn kinases by protein-tyrosine phosphatase RPTPalpha is substrate-specific and compatible with lipid raft localization.
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| Vacaresse N, Møller B, Danielsen EM, Okada M, Sap J.
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| J Biol Chem 283(51):35815-24. Epub 2008 Oct 23.
2008
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| 14 | PTPRA
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| RPTPalpha is required for rigidity-dependent inhibition of extension and differentiation of hippocampal neurons.
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| Kostic A, Sap J, Sheetz MP.
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| J Cell Sci 120(Pt 21):3895-904. Epub 2007 Oct 16.
2007
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| 15 | NCAM1, PTPRA
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| RPTPalpha is essential for NCAM-mediated p59fyn activation and neurite elongation.
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| Bodrikov V, Leshchyns'ka I, Sytnyk V, Overvoorde J, den Hertog J, Schachner M.
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| J Cell Biol 168(1):127-39. Epub 2004 Dec 28.
2005
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| 16 | PTPRA
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| Receptor protein tyrosine phosphatase alpha is essential for hippocampal neuronal migration and long-term potentiation.
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| Petrone A, Battaglia F, Wang C, Dusa A, Su J, Zagzag D, Bianchi R, Casaccia-Bonnefil P, Arancio O, Sap J.
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| EMBO J 22(16):4121-31.
2003
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| 17 | PTPRA
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| The human protein-tyrosine phosphatase PTPalpha/LRP gene (PTPA) is assigned to chromosome 20p13.
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| Jirik FR, et al.
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| Cytogenet Cell Genet 60 : 117-118. 1992
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| 18 | PTPRA
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| The gene for receptor-linked protein-tyrosine-phosphatase (PTPA) is assigned to human chromosome 20p12-pter by in situ hybridization (ISH and FISH).
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| Rao VVNG, et al.
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| Genomics 13 : 906-907. 1992
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| 19 | PTPRA
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| Cloning and chromosomal assignment of a widely expressed human receptor-like protein-tyrosine-phosphatase.
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| Jirik FR, et al.
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| FEBS Lett 273 : 239-242. 1990
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| 20 | PTPRA
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| Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatase expressed in brain.
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| Kaplan R, et al.
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| Proc Natl Acad Sci U S A 87 : 7000-7004. 1990
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| 21 | PTPRA, PTPRB, PTPRD, PTPRE, PTPRG, PTPRZ1
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| Structural diversity and evolution of human receptor-like protein tyrosine phosphatases.
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| Krueger NX, et al.
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| Embo J 9 : 3241-3252. 1990
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| 22 | PTPRA
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| 16.
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| Substrate stiffness and the receptor-type tyrosine-protein phosphatase alpha regulate spreading of colon cancer cells through cytoskeletal contractility.
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| Krndija D, Schmid H, Eismann JL, Lother U, Adler G, Oswald F, Seufferlein T, von Wichert G rndija D, Schmid H, Eismann JL, Lother U, Adler G, Oswald F, Seufferlein T, von Wichert G.
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