Citations for
1PTK7, ROCK2
PTK7-Src Signaling at Epithelial Cell Contacts Mediates Spatial Organization of Actomyosin and Planar Cell Polarity.
Andreeva A, Lee J, Lohia M, Wu X, Macara IG, Lu X.
Dev Cell ev Cell. 2014 Apr 2. pii: S1534-5807(14)00101-4. doi: 10.1016/j.devcel.2014.02.008. [Epub ahead of print] 2014
2PTK7
PTK7 protein is decreased in epithelial ovarian carcinomas with poor prognosis.
Wang H, Li G, Yin Y, Wang J, Wang H, Wei W, Guo Q, Ma H, Shi Q, Zhou X, Wang J.
Int J Clin Exp Pathol 7(11):7881-9. eCollection 2014. 2014
3PTK7
Protein-tyrosine pseudokinase 7 (PTK7) directs cancer cell motility and metastasis.
Golubkov VS, Prigozhina NL, Zhang Y, Stoletov K, Lewis JD, Schwartz PE, Hoffman RM, Strongin AY.
J Biol Chem 289(35):24238-49. doi: 10.1074/jbc.M114.574459. Epub 2014 Jul 8. 2014
4LRP6, PTK7
PTK7 modulates Wnt signaling activity via LRP6.
Bin-Nun N, Lichtig H, Malyarova A, Levy M, Elias S, Frank D.
Development 141(2):410-21. doi: 10.1242/dev.095984. Epub 2013 Dec 18. 2014
5PTK7
Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/β-catenin-dependent cell fate decisions during vertebrate development.
Hayes M, Naito M, Daulat A, Angers S, Ciruna B.
Development 140(8):1807-18. doi: 10.1242/dev.090183. Erratum in: Development. 2013 Apr;140(8):1807. 2013
6ADAM17, PTK7
The cytosolic domain of protein-tyrosine kinase 7 (PTK7), generated from sequential cleavage by a disintegrin and metalloprotease 17 (ADAM17) and γ-secretase, enhances cell proliferation and migration in colon cancer cells.
Na HW, Shin WS, Ludwig A, Lee ST.
J Biol Chem 287(30):25001-9. doi: 10.1074/jbc.M112.348904. Epub 2012 Jun 4. 2012
7PTK7
PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium.
Lee J, Andreeva A, Sipe CW, Liu L, Cheng A, Lu X.
Curr Biol 22(11):956-66. doi: 10.1016/j.cub.2012.03.068. Epub 2012 May 3. 2012
8MMP14, PTK7
Insights into ectodomain shedding and processing of protein-tyrosine pseudokinase 7 (PTK7).
Golubkov VS, Strongin AY.
J Biol Chem 287(50):42009-18. doi: 10.1074/jbc.M112.371153. Epub 2012 Oct 24. 2012
9FLT1, PTK7
Flt-1 regulates vascular endothelial cell migration via a protein tyrosine kinase-7-dependent pathway.
Lee HK, Chauhan SK, Kay E, Dana R.
Blood lood. 2011 Apr 1. [Epub ahead of print] 2011
10PTK7
PTK7: A cell polarity receptor with multiple facets.
Lhoumeau AC, Puppo F, Prébet T, Kodjabachian L, Borg JP.
Cell Cycle 10(8). [Epub ahead of print] 2011
11PTK7, RACK1
RACK1 is a novel interaction partner of PTK7 that is required for neural tube closure.
Wehner P, Shnitsar I, Urlaub H, Borchers A.
Development 138(7):1321-7. Epub 2011 Feb 24. 2011
12PTK7
Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling.
Puppo F, Thomé V, Lhoumeau AC, Cibois M, Gangar A, Lembo F, Belotti E, Marchetto S, Lécine P, Prébet T, Sebbagh M, Shin WS, Lee ST, Kodjabachian L, Borg JP.
EMBO Rep 12(1):43-9. Epub 2010 Dec 3. 2011
13PTK7
PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling.
Peradziryi H, Kaplan NA, Podleschny M, Liu X, Wehner P, Borchers A, Tolwinski NS.
EMBO J 30(18):3729-40. doi: 10.1038/emboj.2011.236. 2011
14CASP10, PTK7
Silencing of PTK7 in colon cancer cells: caspase-10-dependent apoptosis via mitochondrial pathway.
Meng L, Sefah K, O'Donoghue MB, Zhu G, Shangguan D, Noorali A, Chen Y, Zhou L, Tan W.
PLoS One 5(11):e14018. 2010
15PLXNA1, PTK7
PlexinA1 interacts with PTK7 and is required for neural crest migration.
Wagner G, Peradziryi H, Wehner P, Borchers A.
Biochem Biophys Res Commun 402(2):402-7. Epub 2010 Oct 12. 2010
16PTK7
The cell polarity PTK7 receptor acts as a modulator of the chemotherapeutic response in acute myeloid leukemia and impairs clinical outcome.
Prebet T, Lhoumeau AC, Arnoulet C, Aulas A, Marchetto S, Audebert S, Puppo F, Chabannon C, Sainty D, Santoni MJ, Sebbagh M, Summerour V, Huon Y, Shin WS, Lee ST, Esterni B, Vey N, Borg JP.
Blood 116(13):2315-23. Epub 2010 Jun 17. 2010
17PTK7
Soluble PTK7 inhibits tube formation, migration, and invasion of endothelial cells and angiogenesis.
Shin WS, Maeng YS, Jung JW, Min JK, Kwon YG, Lee ST.
Biochem Biophys Res Commun 371(4):793-8. Epub 2008 May 8. 2008
18PTK7
PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates.
Lu X, Borchers AG, Jolicoeur C, Rayburn H, Baker JC, Tessier-Lavigne M.
Nature 430(6995):93-8. 2004
19PTK7
Cloning and characterization of the full-length mouse Ptk7 cDNA encoding a defective receptor protein tyrosine kinase.
Jung JW, Shin WS, Song J, Lee ST.
Gene 328:75-84. 2004
20PTK7
Organization of the human PTK7 gene encoding a receptor protein tyrosine kinase-like molecule and alternative splicing of its mRNA.
Jung JW, Ji AR, Lee J, Kim UJ, Lee ST.
Biochim Biophys Acta 1579(2-3):153-63. 2002
21PTK7
Assignment of PTK7 encoding a receptor protein tyrosine kinase-like molecule to human chromosome 6p21.1-->p12.2 by fluorescence in situ hybridization.
Banga SS, Ozer HL, Park SK, Lee ST.
Cytogenet Cell Genet 76(1-2):43-4. 1997
22DDR2, PTK3B, FRK, PTK6, PTK7, MST1R, RYKP
A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes.
Lee ST, et al.
Oncogene 8 : 3403-3410. 1993