| 1 | PTHLH
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| Parathyroid hormone-related protein regulates integrin α6 and β4 levels via transcriptional and post-translational pathways.
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| Bhatia V, Mula RV, Falzon M.
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| Exp Cell Res 319(10):1419-30. doi: 10.1016/j.yexcr.2013.03.003. Epub 2013 Mar 13.
2013
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| 2 | PTHLH
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| PTHrP regulates the modeling of cortical bone surfaces at fibrous insertion sites during growth.
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| Wang M, VanHouten JN, Nasiri AR, Johnson RL, Broadus AE.
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| J Bone Miner Res 28(3):598-607. doi: 10.1002/jbmr.1801.
2013
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| 3 | PTHLH, SUFU
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| Suppressor of fused (Sufu) mediates the effect of parathyroid hormone-like hormone (Pthlh) on chondrocyte differentiation in the growth plate.
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| Hsu SH, Zhang X, Cheng S, Wunder JS, Hui CC, Alman BA.
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| J Biol Chem 287(43):36222-8. doi: 10.1074/jbc.M112.382275. Epub 2012 Aug 28.
2012
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| 4 | PTHLH
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| The multifaceted actions of PTHrP in skeletal metastasis.
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| Soki FN, Park SI, McCauley LK.
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| Future Oncol 8(7):803-17. doi: 10.2217/fon.12.76. Review.
2012
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| 5 | PTHLH
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| Structure-function relationship of the nuclear localization signal sequence of parathyroid hormone-related protein.
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| Ohshima K, Takeda S, Hirose M, Akiyama Y, Iguchi K, Hoshino M, Yamaguchi K, Mochizuki T.
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| Biomed Res 33(3):191-9.
2012
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| 6 | HTR2A, HTR2B, HTR2C, PTHLH, RUNX2
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| Mammary gland serotonin regulates parathyroid hormone-related protein and other bone-related signals.
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| Hernandez LL, Gregerson KA, Horseman ND.
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| Am J Physiol Endocrinol Metab 302(8):E1009-15. doi: 10.1152/ajpendo.00666.2011. Epub 2012 Feb 7.
2012
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| 7 | PTHLH
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| PTHrP induces autocrine/paracrine proliferation of bone tumor cells through inhibition of apoptosis.
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| Mak IW, Cowan RW, Turcotte RE, Singh G, Ghert M.
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| PLoS One 6(5):e19975. doi: 10.1371/journal.pone.0019975. Epub 2011 May 23.
2011
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| 8 | PTHLH
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| Negative regulation of parathyroid hormone-related protein expression by steroid hormones.
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| Kajitani T, Tamamori-Adachi M, Okinaga H, Chikamori M, Iizuka M, Okazaki T.
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| Biochem Biophys Res Commun 407(3):472-8. doi: 10.1016/j.bbrc.2011.03.037. Epub 2011 Mar 21.
2011
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| 9 | PTHLH
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| Parathyroid hormone-like hormone (PTHLH) represses decidualization of human uterine fibroblast cells by an autocrine/paracrine mechanism.
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| Sherafat-Kazemzadeh R, Schroeder JK, Kessler CA, Handwerger S.
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| J Clin Endocrinol Metab 96(2):509-14. doi: 10.1210/jc.2010-1790. Epub 2010 Nov 10.
2011
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| 10 | PTHLH
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| The expression of PTHLH in human gastric mucosa enterochromaffin-like cells.
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| Liu C, Chen J, Guo Y, Yang L, Zhao C, Bai L.
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| Dig Dis Sci 56(4):993-8. doi: 10.1007/s10620-010-1375-2. Epub 2010 Sep 16.
2011
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| 11 | BDE2, PTHLH
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| Deletion and point mutations of PTHLH cause brachydactyly type E.
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| Klopocki E, Hennig BP, Dathe K, Koll R, de Ravel T, Baten E, Blom E, Gillerot Y, Weigel JF, Krüger G, Hiort O, Seemann P, Mundlos S.
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| Am J Hum Genet 86(3):434-9. Epub 2010 Feb 18.PMID: 20170896 2010
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| 12 | DUP12P, ECDMM2, PTHLH
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| Symmetrical enchondromatosis is associated with duplication of 12p11.23 to 12p11.22 including PTHLH.
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| Collinson M, Leonard SJ, Charlton J, Crolla JA, Silve C, Hall CM, Oglivie C, James MA, Smithson SF.
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| Am J Med Genet A 152A(12):3124-8.PMID: 21082660 2010
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| 13 | PTHLH
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| Parathyroid-related protein plays a critical role in bone invasion by oral squamous cell carcinoma.
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| Takayama Y, Mori T, Nomura T, Shibahara T, Sakamoto M.
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| Int J Oncol 36(6):1387-94.
2010
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| 14 | ADAMTS7, GRN, PTHLH
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| ADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factor.
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| Bai XH, Wang DW, Kong L, Zhang Y, Luan Y, Kobayashi T, Kronenberg HM, Yu XP, Liu CJ.
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| Mol Cell Biol 29(15):4201-19. Epub 2009 Jun 1.
2009
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| 15 | ECDMM2, PTHLH
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| Symmetrical enchondromatosis is associated with disruption of PTHLH.
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| Leonars S, Collinson M, Crolla J, Silve C, Hall CM, Smithson S.F.
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| 2009
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| 16 | ADAMTS12, PTHLH
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| Regulation of chondrocyte differentiation by ADAMTS-12 metalloproteinase depends on its enzymatic activity.
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| Bai XH, Wang DW, Luan Y, Yu XP, Liu CJ.
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| Cell Mol Life Sci 66(4):667-80. doi: 10.1007/s00018-008-8633-x.
2009
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| 17 | PTHLH
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| Parathyroid hormone-related protein (107-139) increases human osteoblastic cell survival by activation of vascular endothelial growth factor receptor-2.
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| Alonso V, de Gortázar AR, Ardura JA, Andrade-Zapata I, Alvarez-Arroyo MV, Esbrit P.
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| J Cell Physiol 217(3):717-27.
2008
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| 18 | PTHLH
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| Tumor expressed PTHrP facilitates prostate cancer-induced osteoblastic lesions.
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| Liao J, Li X, Koh AJ, Berry JE, Thudi N, Rosol TJ, Pienta KJ, McCauley LK.
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| Int J Cancer 123(10):2267-78.
2008
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| 19 | PTHLH
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| Oral squamous cell carcinomas stimulate osteoclast differentiation.
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| Deyama Y, Tei K, Yoshimura Y, Izumiyama Y, Takeyama S, Hatta M, Totsuka Y, Suzuki K.
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| Oncol Rep 20(3):663-8.
2008
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| 20 | EFNB2, PTH, PTHLH
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| EphrinB2 regulation by PTH and PTHrP revealed by molecular profiling in differentiating osteoblasts.
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| Allan EH, Häusler KD, Wei T, Gooi JH, Quinn JM, Crimeen-Irwin B, Pompolo S, Sims NA, Gillespie MT, Onyia JE, Martin TJ.
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| J Bone Miner Res 23(8):1170-81.
2008
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| 21 | PTHLH
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| Parathyroid hormone-related protein (PTHrP) inhibits mitochondrial-dependent apoptosis through CK2.
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| Okoumassoun LE, Russo C, Denizeau F, Averill-Bates D, Henderson JE.
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| J Cell Physiol 212(3):591-9.
2007
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| 22 | ITGA6, ITGB4, PTHLH
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| PTH-related protein upregulates integrin alpha6beta4 expression and activates Akt in breast cancer cells.
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| Shen X, Falzon M.
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| Exp Cell Res 312(19):3822-34. Epub 2006 Aug 17. 2006
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| 23 | PTH, PTH1R, PTHLH, SLC9A3R1
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| Mutation of phenylalanine-34 of parathyroid hormone disrupts NHERF1 regulation of PTH type I receptor signaling.
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| Wheeler D, Sneddon WB.
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| Endocrine 30(3):343-52.
2006
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| 24 | PTHLH, ARRB1
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| The COOH-terminus of parathyroid hormone-related protein (PTHrP) interacts with beta-arrestin 1B.
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| Conlan LA, Martin TJ, Gillespie MT.
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| FEBS Lett 527(1-3):71-5. 2002
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| 25 | FGFR3, IHH, PTHLH
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| A Ser(365)-->Cys mutation of fibroblast growth factor receptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia.
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| Chen L, Li C, Qiao W, Xu X, Deng C.
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| Hum Mol Genet 10(5):457-65. 2001
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| 26 | ATN1, VWF, PTHLH
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| Precise chromosomal locations of the genes for dentatorubral-pallidoluysian atrophy (DRPLA), von Willebrand factor (F8vWF) and parathyroid hormone-like hormone (PTHLH) in human chromosome 12p by deletion mapping.
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| Kuwano A, et al.
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| Hum Genet 97 : 95-98. 1996
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| 27 | PTHLH
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| Overexpression of parathyroid hormone-related protein in the pancreatic islets of transgenic mice causes islet hyperplasia, hyperinsulinemia, and hypoglycemia.
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| Vasavada RC, et al.
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| J Biol Chem 271 : 1200-1208. 1996
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| 28 | PTHLH
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| Molecular characterization of an intragenic minisatellite (VNTR) polymorphism in the human parathyroid hormone-related peptide gene in chromosome region 12p12.1-p11.2.
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| Pausova Z, et al.
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| Genomics 17 : 243-244. 1993
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| 29 | PTHLH
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| Human parathyroid hormone-like peptide gene: HindIII and TaqI RFLPs.
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| Hendy GN, et al.
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| Nucleic Acids Res 18 : 5327. 1990
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| 30 | PTHLH
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| Isolation and characterization of the human parathyroid hormone-like peptide gene.
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| Mangin M, Ikeda K, Dreyer BE, Broadus AE.
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| Proc Natl Acad Sci U S A 86(7):2408-12.
1989
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| 31 | PTHLH
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| Identification of a cDNA encoding a parathyroid hormone-like peptide from a human tumor associated with humoral hypercalcemia of malignancy.
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| Mangin M, et al.
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| Proc Natl Acad Sci U S A 85 : 597-601. 1988
|