| 1 | PTGS2, PTH, TNFSF11
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| Prostaglandin-mediated inhibition of PTH-stimulated β-catenin signaling in osteoblasts by bone marrow macrophages.
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| Estus TL, Choudhary S, Pilbeam CC.
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| Bone 85:123-30. doi: 10.1016/j.bone.2016.01.023.
2016
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| 2 | PTH
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| T cells, osteoblasts, and osteocytes: interacting lineages key for the bone anabolic and catabolic activities of parathyroid hormone.
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| Pacifici R.
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| Ann N Y Acad Sci 1364:11-24. doi: 10.1111/nyas.12969. Review.
2016
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| 3 | KHSRP, PTH, SLC34A1
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| Identification of an RNA-binding protein that is phosphorylated by PTH and potentially mediates PTH-induced destabilization of Npt2a mRNA.
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| Murray RD, Merchant ML, Hardin E, Clark B, Khundmiri SJ, Lederer ED.
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| Am J Physiol Cell Physiol 310(3):C205-15. doi: 10.1152/ajpcell.00192.2015. Epub 2015 Nov 25.
2016
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| 4 | CASR, PTH
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| Localization and function of the renal calcium-sensing receptor.
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| Riccardi D, Valenti G.
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| Nat Rev Nephrol. Jul;12(7):414-25. doi: 10.1038/nrneph.2016.59. Epub 2016 May 9 2016
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| 5 | PTH
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| Association between promoter region genetic variants of PTH SNPs and serum 25(OH)-vitamin D level.
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| Al-Daghri NM, Al-Attas OS, Krishnaswamy S, Yakout SM, Mohammed AK, Alenad AM, Chrousos GP, Alokail MS.
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| Int J Clin Exp Pathol 8(7):8463-71.
2015
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| 6 | PTH
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| Structural characterization of amyloid fibrils from the human parathyroid hormone.
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| Gopalswamy M, Kumar A, Adler J, Baumann M, Henze M, Kumar ST, Fändrich M, Scheidt HA, Huster D, Balbach J.
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| Biochim Biophys Acta 1854(4):249-57. doi: 10.1016/j.bbapap.2014.12.020.
2015
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| 7 | PTH
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| Plasma parathyroid hormone is associated with vascular dementia and cerebral hyperintensities in two community-based cohorts.
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| Hagström E, Kilander L, Nylander R, Larsson EM, Michaëlsson K, Melhus H, Ahlström H, Johansson L, Lind L, Arnlöv J.
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| J Clin Endocrinol Metab 99(11):4181-9. doi: 10.1210/jc.2014-1736.
2014
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| 8 | FGF23, NR4A2, PTH
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| Parathyroid hormone activates the orphan nuclear receptor Nurr1 to induce FGF23 transcription.
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| Meir T, Durlacher K, Pan Z, Amir G, Richards WG, Silver J, Naveh-Many T.
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| Kidney Int 86(6):1106-15. doi: 10.1038/ki.2014.215.
2014
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| 9 | PTH
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| Parathyroid hormone receptor signaling induces bone resorption in the adult skeleton by directly regulating the RANKL gene in osteocytes.
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| Ben-awadh AN, Delgado-Calle J, Tu X, Kuhlenschmidt K, Allen MR, Plotkin LI, Bellido T.
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| Endocrinology 155(8):2797-809. doi: 10.1210/en.2014-1046.
2014
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| 10 | PTH
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| The association of serum parathyroid hormone and severity of coronary artery diseases.
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| Shekarkhar S, Foroughi M, Moatamedi M, Gachkar L.
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| Coron Artery Dis 25(4):339-42. doi: 10.1097/MCA.0000000000000089.
2014
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| 11 | LRP6, PTH
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| Disruption of LRP6 in osteoblasts blunts the bone anabolic activity of PTH.
|
| Li C, Xing Q, Yu B, Xie H, Wang W, Shi C, Crane JL, Cao X, Wan M.
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| J Bone Miner Res 28(10):2094-108. doi: 10.1002/jbmr.1962.
2013
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| 12 | PTH
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| Parathyroid hormone (PTH) decreases sodium-phosphate cotransporter type IIa (NpT2a) mRNA stability.
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| Murray RD, Holthouser K, Clark BJ, Salyer SA, Barati MT, Khundmiri SJ, Lederer ED.
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| Am J Physiol Renal Physiol 304(8):F1076-85. doi: 10.1152/ajprenal.00632.2012.
2013
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| 13 | MEF2C, POSTN, PTH, SOST
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| Regulation of beta catenin signaling and parathyroid hormone anabolic effects in bone by the matricellular protein periostin.
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| Bonnet N, Conway SJ, Ferrari SL.
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| Proc Natl Acad Sci U S A 109(37):15048-53. doi: 10.1073/pnas.1203085109.
2012
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| 14 | PTH
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| Usefulness of parathyroid hormone as a predictor of heart failure with preserved ejection fraction.
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| Altay H, Zorlu A, Bilgi M, Erol T, Yilmaz MB.
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| Biomarkers 17(5):447-54. doi: 10.3109/1354750X.2012.685182.
2012
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| 15 | PTH
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| Decreased PTH levels accompanied by low bone formation are associated with vertebral fractures in postmenopausal women with type 2 diabetes.
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| Yamamoto M, Yamaguchi T, Nawata K, Yamauchi M, Sugimoto T.
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| J Clin Endocrinol Metab 97(4):1277-84. doi: 10.1210/jc.2011-2537.
2012
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| 16 | PRG4, PTH
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| Proteoglycan 4: a dynamic regulator of skeletogenesis and parathyroid hormone skeletal anabolism.
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| Novince CM, Michalski MN, Koh AJ, Sinder BP, Entezami P, Eber MR, Pettway GJ, Rosol TJ, Wronski TJ, Kozloff KM, McCauley LK.
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| J Bone Miner Res 27(1):11-25. doi: 10.1002/jbmr.508.
2012
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| 17 | ELF4, MAB21L1, PTH
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| PTH regulates myleoid ELF-1-like factor (MEF)-induced MAB-21-like-1 (MAB21L1) expression through the JNK1 pathway.
|
| Kim BG, Park YJ, Libermann TA, Cho JY.
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| J Cell Biochem 112(8):2051-61. doi: 10.1002/jcb.23124.
2011
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| 18 | ATF4, FGF2, PTH
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| The impaired bone anabolic effect of PTH in the absence of endogenous FGF2 is partially due to reduced ATF4 expression.
|
| Fei Y, Xiao L, Hurley MM.
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| Biochem Biophys Res Commun 412(1):160-4. Epub 2011 Jul 22.
2011
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| 19 | GNAQ, PTH
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| G alpha(q) signal in osteoblasts is inhibitory to the osteoanabolic action of parathyroid hormone.
|
| Ogata N, Shinoda Y, Wettschureck N, Offermanns S, Takeda S, Nakamura K, Segre GV, Chung UI, Kawaguchi H.
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| J Biol Chem 286(15):13733-40. doi: 10.1074/jbc.M110.200196. Epub 2011 Feb 23.
2011
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| 20 | PRG4, PTH
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| Proteoglycan 4, a novel immunomodulatory factor, regulates parathyroid hormone actions on hematopoietic cells.
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| Novince CM, Koh AJ, Michalski MN, Marchesan JT, Wang J, Jung Y, Berry JE, Eber MR, Rosol TJ, Taichman RS, McCauley LK.
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| Am J Pathol 179(5):2431-42. doi: 10.1016/j.ajpath.2011.07.032.
2011
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| 21 | PTH
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| Dual role of parathyroid hormone in endothelial progenitor cells and marrow stromal mesenchymal stem cells.
|
| Di Bernardo G, Galderisi U, Fiorito C, Squillaro T, Cito L, Cipollaro M, Giordano A, Napoli C.
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| J Cell Physiol 222(2):474-80.PMID: 19918796 2010
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| 22 | IL21R, PTH
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| IL21R and PTH may underlie variation of femoral neck bone mineral density as revealed by a genome-wide association study.
|
| Guo Y, Zhang LS, Yang TL, Tian Q, Xiong DH, Pei YF, Deng HW.
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| J Bone Miner Res 25(5):1042-8.
2010
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| 23 | MMP13, PTH, RUNX2
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| Identification and characterization of Runx2 phosphorylation sites involved in matrix metalloproteinase-13 promoter activation.
|
| Selvamurugan N, Shimizu E, Lee M, Liu T, Li H, Partridge NC.
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| FEBS Lett 583(7):1141-6. Epub 2009 Mar 3.
2009
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| 24 | PTH
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| Human PTH gene regulation in vivo using transgenic mice.
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| Lavi-Moshayoff V, Silver J, Naveh-Many T.
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| Am J Physiol Renal Physiol 297(3):F713-9. Epub 2009 Jul 1.PMID: 19570881 2009
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| 25 | PTH
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| Parathyroid hormone suppresses insulin signaling in adipocytes.
|
| Chang E, Donkin SS, Teegarden D.
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| Mol Cell Endocrinol 307(1-2):77-82. Epub 2009 Apr 9.PMID: 19524129 2009
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| 26 | IL18, PTH
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| Interleukin-18 is regulated by parathyroid hormone and is required for its bone anabolic actions.
|
| Raggatt LJ, Qin L, Tamasi J, Jefcoat SC Jr, Shimizu E, Selvamurugan N, Liew FY, Bevelock L, Feyen JH, Partridge NC.
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| J Biol Chem 283(11):6790-8. Epub 2007 Dec 28. 2008
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| 27 | EFNB2, PTH, PTHLH
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| EphrinB2 regulation by PTH and PTHrP revealed by molecular profiling in differentiating osteoblasts.
|
| Allan EH, Häusler KD, Wei T, Gooi JH, Quinn JM, Crimeen-Irwin B, Pompolo S, Sims NA, Gillespie MT, Onyia JE, Martin TJ.
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| J Bone Miner Res 23(8):1170-81.
2008
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| 28 | ANKH,BGLAP,PTH
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| Contribution of the putative genetic factors and ANKH gene polymorphisms to variation of circulating calciotropic molecules, PTH and BGP.
|
| Vistoropsky Y, Keter M, Malkin I, Trofimov S, Kobyliansky E, Livshits G.
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| Hum Mol Genet 16(10):1233-40. Epub 2007 Apr 2. 2007
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| 29 | PTH
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| Signal sequence mutation in autosomal dominant form of hypoparathyroidism induces apoptosis that is corrected by a chemical chaperone.
|
| Datta R, Waheed A, Shah GN, Sly WS.
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| Proc Natl Acad Sci U S A 104(50):19989-94. Epub 2007 Dec 3. 2007
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| 30 | MEF2A, MEF2B, MEF2C, PTH, SOST
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| Control of the SOST bone enhancer by PTH using MEF2 transcription factors.
|
| Leupin O, Kramer I, Collette NM, Loots GG, Natt F, Kneissel M, Keller H.
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| J Bone Miner Res 22(12):1957-67.PMID: 17696759 2007
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| 31 | PTH, PTH1R, PTHLH, SLC9A3R1
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| Mutation of phenylalanine-34 of parathyroid hormone disrupts NHERF1 regulation of PTH type I receptor signaling.
|
| Wheeler D, Sneddon WB.
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| Endocrine 30(3):343-52.
2006
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| 32 | PTH, SOST
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| SOST is a target gene for PTH in bone.
|
| Keller H, Kneissel M.
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| Bone 37(2):148-58. 2005
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| 33 | PTH, CASR, HYPOCA
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| A novel mutation in the calcium-sensing receptor responsible for autosomal dominant hypocalcemia in a family with two uncommon parathyroid hormone polymorphisms.
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| Alvarez-Hernandez D, Santamaria I, Rodriguez-Garcia M, Iglesias P, Delgado-Lillo R, Cannata-Andia JB.
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| J Mol Endocrinol 31(2):255-62. 2003
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| 34 | PTH
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| Parathyroid hormone stimulates receptor activator of NFkappa B ligand and inhibits osteoprotegerin expression via protein kinase A activation of cAMP-response element-binding protein.
|
| Fu Q, Jilka RL, Manolagas SC, O'Brien CA.
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| J Biol Chem 277(50):48868-75. 2002
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| 35 | PTH
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| A novel mutation of the signal peptide of the preproparathyroid hormone gene associated with autosomal recessive familial isolated hypoparathyroidism.
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| Sunthornthepvarakul T, Churesigaew S, Ngowngarmratana S.
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| J Clin Endocrinol Metab 84(10):3792-6. 1999
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| 36 | MYOD1, PTH, INS
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| An ordered Notl fragment map of human chromosome band 11p15.
|
| Higgins MJ, et al.
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| Genomics 23 : 211-222. 1994
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| 37 | PTH
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| Characterization of two novel polymorphisms at the human parathyroid hormone gene locus.
|
| Mullersman JE, et al.
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| Hum Genet 88 : 589-592. 1992
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| 38 | PTH
|
| A donor splice site mutation in the parathyroid hormone gene is associated with autosomal recessive hypoparathyroidism.
|
| Parkinson DB, et al.
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| Nat Genet 1 : 149-152. 1992
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| 39 | PTH
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| Analysis of the preproPTH gene by denaturing gradient gel electrophoresis in familial isolated hpoparathyroidism.
|
| Miric A, et al.
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| J Clin Endocrinol Metab 74 : 509-516. 1992
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| 40 | PTH
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| Ectopic transcription of the parathyroid hormone gene in lymphocytes, lymphoblastoid cells and tumour tissue.
|
| Handt O, Reis A, Schmidtke J.
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| J Endocrinol 135(2):249-56.PMID: 1474331 1992
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| 41 | PTH
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| DraII and XmnI polymorphisms at the human parathyroid hormone locus.
|
| Shields JJ, et al.
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| Nucleic Acids Res 19 : 4312. 1991
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| 42 | PTH
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| Regional mapping of the parathyroid hormone gene (PTH) by cytogenetic and molecular studies.
|
| Tonoki H, et al.
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| Cytogenet Cell Genet 56 : 103-104. 1991
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| 43 | PTH
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| Mutation of the signal peptide-encoding region of the preproparathyroid hormone gene in familial isolated hypoparathyroidism.
|
| Arnold A, et al.
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| J Clin Invest 86 : 1084-1087. 1990
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| 44 | HBG2, PTH
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| Single-sperm typing : determination of genetic distance between the Ggamma-globin and parathyroid hormone loci by using the polymerase chain reaction and allele-specific oligomers.
|
| Cui X, et al.
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| Proc Natl Acad Sci U S A 86 : 9389-9393. 1989
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| 45 | PTH
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| Exclusion of close linkage between the parathyroid hormone gene and a mutant gene locus causing idiopathic hypoparathyroidism.
|
| Schmidtke J, et al.
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| J Med Genet 23 : 217-219. 1986
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| 46 | CALCA, PTH
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| Parathyroid hormone and calcitonin are tightly linked and have been placed on the genetic map of chromosome 11p.
|
| Holm T, et al.
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| (HGM8) Cytogenet Cell Genet 40 : 653-654. 1985
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| 47 | HB-NA@, PTH, INS, LDHA
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| Mapping parathyroid hormone, beta-globin, insulin, and LDH-A genes within the human chromosome 11 short arm by spot blotting sorted chromosomes.
|
| Lebo RV, et al.
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| Hum Genet 69 : 316-320. 1985
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| 48 | INS, PTH
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| Chromosome mapping of genes on the short arm of human chromosome 11: parathyroid hormone gene is at 11p15 together with the genes for insulin, c-Harvey-ras 1, and beta-hemoglobin.
|
| Zabel BU, et al.
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| Cytogenet Cell Genet 39 : 200-205. 1985
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| 49 | HB-NA@, HBB, HBBP1, HBD, HBE1, HBG1, HBG2, HRAS, INS, MODY10, PTH
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| Germ-line chromosomal localization of genes in chromosome 11p linkage: parathyroid hormone, beta-globin, c-H-ras-1, and insulin.
|
| Chaganti RSK, et al.
|
| Somat Cell Mol Genet 11 : 197-202. 1985
|
| 50 | PTH
|
| Parathyroid hormone gene is on the short arm of human chromosome 11.
|
| Naylor SL, et al.
|
| (HGM7) Cytogenet Cell Genet 37 : 551-552. 1984
|
| 51 | PTH
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| Assignment of the human parathyroid hormone gene to chromosome 11.
|
| Mayer H, et al.
|
| Hum Genet 64 : 283-285. 1983
|