| 1 | PDZK1, PTGIR
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| Interaction of the human prostacyclin receptor with the PDZ adapter protein PDZK1: role in endothelial cell migration and angiogenesis.
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| Turner EC, Mulvaney EP, Reid HM, Kinsella BT.
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| Mol Biol Cell 22(15):2664-79. Epub 2011 Jun 8.
2011
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| 2 | PTGIR
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| Identification of a novel endoplasmic reticulum export motif within the eighth α-helical domain (α-H8) of the human prostacyclin receptor.
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| Donnellan PD, Kimbembe CC, Reid HM, Kinsella BT.
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| Biochim Biophys Acta 1808(4):1202-18. Epub 2011 Jan 9.
2011
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| 3 | PDZK1, PTGIR
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| Interaction of the human prostacyclin receptor with the PDZ adapter protein PDZK1: role in endothelial cell migration and angiogenesis.
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| Turner EC, Mulvaney EP, Reid HM, Kinsella BT.
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| Mol Biol Cell. 22(15):2664-79 2011
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| 4 | PTGIR, RAB11A
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| Interaction of the human prostacyclin receptor with Rab11: characterization of a novel Rab11 binding domain within alpha-helix 8 that is regulated by palmitoylation.
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| Reid HM, Mulvaney EP, Turner EC, Kinsella BT.
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| J Biol Chem 285(24):18709-26. Epub 2010 Apr 15. 2010
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| 5 | PTGIR
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| Dominant negative actions of human prostacyclin receptor variant through dimerization: implications for cardiovascular disease.
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| Ibrahim S, Tetruashvily M, Frey AJ, Wilson SJ, Stitham J, Hwa J, Smyth EM.
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| Arterioscler Thromb Vasc Biol 30(9):1802-9. Epub 2010 Jun 3.
2010
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| 6 | PTGIR
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| Prostacyclin receptor suppresses cardiac fibrosis: role of CREB phosphorylation.
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| Chan EC, Dusting GJ, Guo N, Peshavariya HM, Taylor CJ, Dilley R, Narumiya S, Jiang F.
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| J Mol Cell Cardiol 49(2):176-85. Epub 2010 Apr 18.
2010
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| 7 | PTGIR
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| Prostaglandin I2 promotes recruitment of endothelial progenitor cells and limits vascular remodeling.
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| Kawabe J, Yuhki K, Okada M, Kanno T, Yamauchi A, Tashiro N, Sasaki T, Okumura S, Nakagawa N, Aburakawa Y, Takehara N, Fujino T, Hasebe N, Narumiya S, Ushikubi F.
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| Arterioscler Thromb Vasc Biol 30(3):464-70. Epub 2009 Dec 10.
2010
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| 8 | PTGIR
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| Transcriptional regulation of the human prostacyclin receptor gene is dependent on Sp1, PU.1 and Oct-1 in megakaryocytes and endothelial cells.
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| Turner EC, Kinsella BT.
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| J Mol Biol 386(3):579-97. Epub 2008 Dec 24.
2009
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| 9 | PTGIR
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| Immature and mature species of the human Prostacyclin Receptor are ubiquitinated and targeted to the 26S proteasomal or lysosomal degradation pathways, respectively.
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| Donnellan PD, Kinsella BT.
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| J Mol Signal. 4:7. 2009
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| 10 | PTGIR
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| Recycling of the human prostacyclin receptor is regulated through a direct interaction with Rab11a GTPase.
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| Wikström K, Reid HM, Hill M, English KA, O'Keeffe MB, Kimbembe CC, Kinsella BT.
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| Cell Signal 20(12):2332-46. Epub 2008 Sep 7.
2008
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| 11 | PTGIR
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| Prostacyclin receptor signaling and early embryo development in the mouse.
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| Huang JC, Wun WS, Goldsby JS, Egan K, FitzGerald GA, Wu KK.
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| Hum Reprod 22(11):2851-6. Epub 2007 Sep 28.
2007
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| 12 | PTGIR
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| Arginine (CGC) codon targeting in the human prostacyclin receptor gene (PTGIR) and G-protein coupled receptors (GPCR).
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| Stitham J, Arehart EJ, Gleim S, Douville K, MacKenzie T, Hwa J.
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| Gene 396(1):180-7. Epub 2007 Apr 1.
2007
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| 13 | PDE6D, PTGIR
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| Internalization and recycling of the human prostacyclin receptor is modulated through its isoprenylation-dependent interaction with the delta subunit of cGMP phosphodiesterase 6.
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| Wilson SJ, Smyth EM.
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| J Biol Chem 281(17):11780-6. Epub 2006 Mar 9.
2006
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| 14 | PTGIR
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| Decreased susceptibility to renovascular hypertension in mice lacking the prostaglandin I2 receptor IP.
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| Fujino T, Nakagawa N, Yuhki K, Hara A, Yamada T, Takayama K, Kuriyama S, Hosoki Y, Takahata O, Taniguchi T, Fukuzawa J, Hasebe N, Kikuchi K, Narumiya S, Ushikubi F.
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| J Clin Invest. 114(6):805-12. 2004
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| 15 | PTGIR
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| Prostacyclin enhances the expression of LPS/INF-gamma-induced nitric oxide synthase in human monocytes.
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| Plum J, Huang C, Grabensee B, Schror K, Meyer-Kirchrath J.
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| Nephron 91(3):391-8. 2002
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| 16 | PTGIR
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| Role of prostacyclin in the cardiovascular response to thromboxane A2.
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| Cheng Y, Austin SC, Rocca B, Koller BH, Coffman TM, Grosser T, Lawson JA, FitzGerald GA.
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| Science. 296(5567):539-41. 2002
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| 17 | PTGIR
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| Phosphorylation of the prostacyclin receptor during homologous desensitization. A critical role for protein kinase c.
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| Smyth EM, Li WH, FitzGerald GA.
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| J Biol Chem. 273(36):23258-66. 1998
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| 18 | PTGIR
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| Altered pain perception and inflammatory response in mice lacking prostacyclin receptor.
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| Murata T, Ushikubi F, Matsuoka T, Hirata M, Yamasaki A, Sugimoto Y, Ichikawa A, Aze Y, Tanaka T, Yoshida N, Ueno A, Oh-ishi S, Narumiya S.
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| Nature. 388(6643):678-82. 1997
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| 19 | PTGER1, PTGER2, PTGER3, PTGER4, PTGFR, PTGIR, TBXA2R
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| Chromosomal localization of the human prostanoid receptor gene family.
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| Duncan AMV, et al.
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| Genomics 25 : 740-742. 1995
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| 20 | PTGIR
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| Structural organization and chromosomal assignment of the human prostacyclin receptor gene.
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| Ogawa Y, et al.
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| Genomics 27 : 142-148. 1995
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| 21 | PTGIR
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| Molecular cloning of human prostacyclin receptor cDNA and its gene expression in the cardiovascular system.
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| Nakagawa O, et al.
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| Circulation 90 : 1643-1647. 1994
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| 22 | PTGIR
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| Cloning and expression of a cDNA for the human prostanoid IP receptor.
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| Boie Y, Rushmore TH, Darmon-Goodwin A, Grygorczyk R, Slipetz DM, Metters KM, Abramovitz M.
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| J Biol Chem. 269(16):12173-8. 1994
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