| 1 | PTF1A
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| Misexpression of ptf1a in cortical pyramidal cells in vivo promotes an inhibitory peptidergic identity.
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| Russ JB, Borromeo MD, Kollipara RK, Bommareddy PK, Johnson JE, Kaltschmidt JA.
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| J Neurosci 35(15):6028-37. doi: 10.1523/JNEUROSCI.3821-14.2015.
2015
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| 2 | FOXN4, PTF1A, RORB
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| Tfap2a and 2b act downstream of Ptf1a to promote amacrine cell differentiation during retinogenesis.
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| Jin K, Jiang H, Xiao D, Zou M, Zhu J, Xiang M.
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| Mol Brain 8:28. doi: 10.1186/s13041-015-0118-x.
2015
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| 3 | PTF1A, TRIP12
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| The E3 ubiquitin ligase thyroid hormone receptor-interacting protein 12 targets pancreas transcription factor 1a for proteasomal degradation.
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| Hanoun N, Fritsch S, Gayet O, Gigoux V, Cordelier P, Dusetti N, Torrisani J, Dufresne M.
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| J Biol Chem 289(51):35593-604. doi: 10.1074/jbc.M114.620104. Epub 2014 Oct 29.
2014
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| 4 | MKNK1, PTF1A
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| Mnk1 is a novel acinar cell-specific kinase required for exocrine pancreatic secretion and response to pancreatitis in mice.
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| Cendrowski J, Sánchez-Arévalo Lobo VJ, Sendler M, Salas A, Kühn JP, Molero X, Fukunaga R, Mayerle J, Lerch MM, Real FX.
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| Gut ut. 2014 Jul 18. pii: gutjnl-2013-306068. doi: 10.1136/gutjnl-2013-306068. [Epub ahead of print]
2014
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| 5 | ATOH1, PTF1A
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| Specification of spatial identities of cerebellar neuron progenitors by ptf1a and atoh1 for proper production of GABAergic and glutamatergic neurons.
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| Yamada M, Seto Y, Taya S, Owa T, Inoue YU, Inoue T, Kawaguchi Y, Nabeshima Y, Hoshino M.
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| J Neurosci 34(14):4786-800. doi: 10.1523/JNEUROSCI.2722-13.2014.
2014
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| 6 | ASCL1, PTF1A
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| Ascl1 as a novel player in the Ptf1a transcriptional network for GABAergic cell specification in the retina.
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| Mazurier N, Parain K, Parlier D, Pretto S, Hamdache J, Vernier P, Locker M, Bellefroid E, Perron M.
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| PLoS One 9(3):e92113. doi: 10.1371/journal.pone.0092113. eCollection 2014.
2014
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| 7 | IDPC, PTF1A
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| Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis.
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| Weedon MN, Cebola I, Patch AM, Flanagan SE, De Franco E, Caswell R, Rodríguez-Seguí SA, Shaw-Smith C, Cho CH, Lango Allen H, Houghton JA, Roth CL, Chen R, Hussain K, Marsh P, Vallier L, Murray A; International Pancreatic Agenesis Consortium, Ellard S, Ferrer J, Hattersley AT.
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| Nat Genet 46(1):61-4. doi: 10.1038/ng.2826. Epub 2013 Nov 10.
2014
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| 8 | PTF1A
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| Ectopic expression of Ptf1a induces spinal defects, urogenital defects, and anorectal malformations in Danforth's short tail mice.
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| Semba K, Araki K, Matsumoto K, Suda H, Ando T, Sei A, Mizuta H, Takagi K, Nakahara M, Muta M, Yamada G, Nakagata N, Iida A, Ikegawa S, Nakamura Y, Araki M, Abe K, Yamamura K.
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| PLoS Genet 9(2):e1003204. doi: 10.1371/journal.pgen.1003204. Epub 2013 Feb 21.
2013
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| 9 | CTNNBIP1, PTF1A
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| ICAT is a novel Ptf1a interactor that regulates pancreatic acinar differentiation and displays altered expression in tumours.
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| Campos ML, Sánchez-Arévalo Lobo VJ, Rodolosse A, Gottardi CJ, Mafficini A, Beghelli S, Scardoni M, Bassi C, Scarpa A, Real FX.
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| Biochem J 451(3):395-405. doi: 10.1042/BJ20120873. Erratum in: Biochem J. 2013 Jul 1;453(1):154.
2013
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| 10 | FOXN4, PTF1A, RORB
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| An isoform of retinoid-related orphan receptor β directs differentiation of retinal amacrine and horizontal interneurons.
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| Liu H, Kim SY, Fu Y, Wu X, Ng L, Swaroop A, Forrest D.
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| Nat Commun 4:1813. doi: 10.1038/ncomms2793.
2013
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| 11 | DLL1, HES1, PTF1A
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| Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism.
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| Ahnfelt-Rřnne J, Jřrgensen MC, Klinck R, Jensen JN, Füchtbauer EM, Deering T, MacDonald RJ, Wright CV, Madsen OD, Serup P.
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| Development 139(1):33-45. doi: 10.1242/dev.071761. Epub 2011 Nov 17.
2012
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| 12 | NKX6-1, NKX6-2, PTF1A
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| Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors.
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| Schaffer AE, Freude KK, Nelson SB, Sander M.
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| Dev Cell 18(6):1022-9. doi: 10.1016/j.devcel.2010.05.015.
2010
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| 13 | KIRREL2, NPHS1, PTF1A
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| Ptf1a directly controls expression of immunoglobulin superfamily molecules Nephrin and Neph3 in the developing central nervous system.
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| Nishida K, Hoshino M, Kawaguchi Y, Murakami F.
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| J Biol Chem 285(1):373-80. doi: 10.1074/jbc.M109.060657. Epub 2009 Nov 2.
2010
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| 14 | IDPC, PTF1A
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| A Turkish newborn infant with cerebellar agenesis/neonatal diabetes mellitus and PTF1A mutation.
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| Tutak E, Satar M, Yapicioğlu H, Altintaş A, Narli N, Hergüner O, Bayram Y.
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| Genet Couns 20(2):147-52.
2009
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| 15 | PTF1A
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| Origin of climbing fiber neurons and their developmental dependence on Ptf1a.
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| Yamada M, Terao M, Terashima T, Fujiyama T, Kawaguchi Y, Nabeshima Y, Hoshino M.
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| J Neurosci 27(41):10924-34. 2007
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| 16 | PTF1A, RBPJL
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| PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L.
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| Beres TM, Masui T, Swift GH, Shi L, Henke RM, MacDonald RJ.
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| Mol Cell Biol 26(1):117-30. 2006
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| 17 | PTF1A, IDPC
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| Mutations in PTF1A cause pancreatic and cerebellar agenesis.
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| Sellick GS, Barker KT, Stolte-Dijkstra I, Fleischmann C, Coleman RJ, Garrett C, Gloyn AL, Edghill EL, Hattersley AT, Wellauer PK, Goodwin G, Houlston RS.
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| Nat Genet 36(12):1301-5. Epub 2004 Dec. 2004
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| 18 | IDPC, PTF1A
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| Mutations in PTF1A cause pancreatic and cerebellar agenesis.
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| Sellick GS, Barker KT, Stolte-Dijkstra I, Fleischmann C, Coleman RJ, Garrett C, Gloyn AL, Edghill EL, Hattersley AT, Wellauer PK, Goodwin G, Houlston RS.
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| Nat Genet 36(12):1301-5. Epub 2004 Nov 14.
2004
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| 19 | IDPC, PTF1A
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| Mutations in PTF1A cause pancreatic and cerebellar agenesis.
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| Sellick GS, Barker KT, Stolte-Dijkstra I, Fleischmann C, Coleman RJ, Garrett C, Gloyn AL, Edghill EL, Hattersley AT, Wellauer PK, Goodwin G, Houlston RS.
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| Nat Genet 36(12):1301-5. Epub 2004 Nov 14.
2004
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| 20 | IDPC, PTF1A
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| A novel gene for neonatal diabetes maps to chromosome 10p12.1-p13.
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| Sellick GS, Garrett C, Houlston RS.
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| Diabetes 52(10):2636-8. 2003
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| 21 | PTF1A
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| Constitutive expression of the gene for the cell-specific p48 DNA-binding subunit of pancreas transcription factor 1 in cultured cells is under control of binding sites for transcription factors Sp1 and alphaCbf.
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| Knofler M, Krapp A, Hagenbuchle O, Wellauer PK.
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| J Biol Chem 271(36):21993-2002. 1996
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