| 1 | PTCH1, PTCH2, SMO
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| Patched1 and Patched2 inhibit Smoothened non-cell autonomously.
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| Roberts B, Casillas C, Alfaro AC, Jägers C, Roelink H.
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| Elife 5. pii: e17634. doi: 10.7554/eLife.17634.
2016
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| 2 | PTCH1, PTCH2, SMO
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| Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development.
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| Zhulyn O, Nieuwenhuis E, Liu YC, Angers S, Hui CC.
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| Dev Biol 397(2):191-202. doi: 10.1016/j.ydbio.2014.10.023. Epub 2014 Nov 13.
2015
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| 3 | PTCH1, PTCH2
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| Patched 1 and patched 2 redundancy has a key role in regulating epidermal differentiation.
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| Adolphe C, Nieuwenhuis E, Villani R, Li ZJ, Kaur P, Hui CC, Wainwright BJ.
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| J Invest Dermatol 134(7):1981-90. doi: 10.1038/jid.2014.63. Epub 2014 Feb 3.
2014
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| 4 | HHIP, PTCH1, PTCH2
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| Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning.
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| Holtz AM, Peterson KA, Nishi Y, Morin S, Song JY, Charron F, McMahon AP, Allen BL.
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| Development 140(16):3423-34. doi: 10.1242/dev.095083.
2013
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| 5 | BCNS, PTCH2
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| Frameshift mutation in the PTCH2 gene can cause nevoid basal cell carcinoma syndrome.
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| Fujii K, Ohashi H, Suzuki M, Hatsuse H, Shiohama T, Uchikawa H, Miyashita T.
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| Fam Cancer 12(4):611-4. doi: 10.1007/s10689-013-9623-1.
2013
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| 6 | PTCH2
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| Ectopic proliferation contributes to retinal dysplasia in the juvenile zebrafish patched2 mutant eye.
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| Bibliowicz J, Gross JM.
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| Invest Ophthalmol Vis Sci 52(12):8868-77. doi: 10.1167/iovs.11-8033.
2011
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| 7 | PTCH2
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| A susceptibility locus on 1p32-1p34 for congenital macrostomia in a Chinese family and identification of a novel PTCH2 mutation.
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| Fan Z, Du J, Liu H, Zhang H, Dlugosz AA, Wang CY, Fan M, Shen Y, Wang S.
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| Am J Med Genet A 149A(3):521-4. No abstract available.
2009
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| 8 | BCNS, PTCH2
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| A missense mutation in PTCH2 underlies dominantly inherited NBCCS in a Chinese family.
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| Fan Z, Li J, Du J, Zhang H, Shen Y, Wang CY, Wang S.
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| J Med Genet 45(5):303-8. doi: 10.1136/jmg.2007.055343. Epub 2008 Feb 19.
2008
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| 9 | AADACL3, AADACL4, ADCK3, AGBL1, AGBL4, ANKRD13C, ANKRD45, ATP13A2, B3GALT2, B3GALT4, B3GALT6, B4GALT2, B4GALT3, B4GALT4, B4GALT5, B4GALT6, BLZF1, BSDC1, C1orf100, C1orf101, C1orf103, C1orf104, C1orf110, C1orf115, C1orf120, C1orf122, C1orf123, C1orf126, C1orf130, C1orf31, C1orf35, C1orf49, C1orf51, C1orf53, C1orf54, C1orf65, C1orf74, C1orf95, C1orf97, CCDC76, CCDC76, CCT3, COL16A1, DDX59, DENND2D, DNALI1, DPM3, FAM131C, FAM167B, FAM176B, FAM76A, FAM78B, FHAD1, FMO4, GJC2, GLUL, GNPAT, GPR157, GPR161, GPR89A, GPR89B, GPR89C, HMGN2, HSPB7, IBA57, ITGB3BP, KIAA1107, KLHL20, MAN1A2, MAP1LC3C, METTL11B, MLK4, MRTO4, NFYC, OR2M3, OR2M7, OR2T12, OR2T33, OR2T34, OR4F16, PEX10, PLA2G2D, PRAMEF12, PRAMEF13, PRAMEF14, PRAMEF15, PRAMEF16, PRAMEF17, PRAMEF18, PRAMEF19, PRAMEF20, PRAMEF21, PTCH2, RC3H1, RGS18, RIMKLA, SEP15, SLC35D1, SMYD2, SRARP, STX6, TBX15, TRIM62, TTLL7, VASH2, WLS, ZBTB18, ZMYM1, ZNF436, ZNF642
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| The DNA sequence and biological annotation of human chromosome 1.
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| Gregory SG, Barlow KF, McLay KE, Kaul R, Swarbreck D, Dunham A, Scott CE, Howe KL, Woodfine K, Spencer CC, Jones MC, Gillson C, Searle S, Zhou Y, Kokocinski F, McDonald L, Evans R, Phillips K, Atkinson A, Cooper R, Jones C, Hall RE, Andrews TD, Lloyd C, Ainscough R, Almeida JP, Ambrose KD, Anderson F, Andrew RW, Ashwell RI, Aubin K, Babbage AK, Bagguley CL, Bailey J, Beasley H, Bethel G, Bird CP, Bray-Allen S, Brown JY, Brown AJ, Buckley D, Burton J, Bye J, Carder C, Chapman JC, Clark SY, Clarke G, Clee C, Cobley V, Collier RE, Corby N, Coville GJ, Davies J, Deadman R, Dunn M, Earthrowl M, Ellington AG, Errington H, Frankish A, Frankland J, French L, Garner P, Garnett J, Gay L, Ghori MR, Gibson R, Gilby LM, Gillett W, Glithero RJ, Grafham DV, Griffiths C, Griffiths-Jones S, Grocock R, Hammond S, Harrison ES, Hart E, Haugen E, Heath PD, Holmes S, Holt K, Howden PJ, Hunt AR, Hunt SE, Hunter G, Isherwood J, James R, Johnson C, Johnson D, Joy A, Kay M, Kershaw JK, Kibukawa M, Kimberley AM, King A, Knights AJ, Lad H, Laird G, Lawlor S, Leongamornlert DA, Lloyd DM, Loveland J, Lovell J, Lush MJ, Lyne R, Martin S, Mashreghi-Mohammadi M, Matthews L, Matthews NS, McLaren S, Milne S, Mistry S, Moore MJ, Nickerson T, O'Dell CN, Oliver K, Palmeiri A, Palmer SA, Parker A, Patel D, Pearce AV, Peck AI, Pelan S, Phelps K, Phillimore BJ, Plumb R, Rajan J, Raymond C, Rouse G, Saenphimmachak C, Sehra HK, Sheridan E, Shownkeen R, Sims S, Skuce CD, Smith M, Steward C, Subramanian S, Sycamore N, Tracey A, Tromans A, Van Helmond Z, Wall M, Wallis JM, White S, Whitehead SL, Wilkinson JE, Willey DL, Williams H, Wilming L, Wray PW, Wu Z, Coulson A, Vaudin M, Sulston JE, Durbin R, Hubbard T, Wooster R, Dunham I, Carter NP, McVean G, Ross MT, Harrow J, Olson MV, Beck S, Rogers J, Bentley DR, Banerjee R, Bryant SP, Burford DC, Burrill WD, Clegg SM, Dhami P, Dovey O, Faulkner LM, Gribble SM, Langford CF, Pandian RD, Porter KM, Prigmore E.
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| Nature 441(7091):315-21. 2006
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| 10 | PTCH2
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| Mice with a targeted mutation of patched2 are viable but develop alopecia and epidermal hyperplasia.
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| Nieuwenhuis E, Motoyama J, Barnfield PC, Yoshikawa Y, Zhang X, Mo R, Crackower MA, Hui CC.
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| Mol Cell Biol 26(17):6609-22.
2006
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| 11 | PTCH2
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| Distinct roles of PTCH2 splice variants in Hedgehog signalling.
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| Rahnama F, ToftgŒrd R, Zaphiropoulos PG.
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| Biochem J 378(Pt 2):325-34. 2004
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| 12 | DHCR7, HMGCR, NPC1, PTCH1, PTCH2, SCAP
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| The sterol-sensing domain: multiple families, a unique role?
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| Kuwabara PE, Labouesse M.
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| Trends Genet 18(4):193-201. 2002
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| 13 | PTCH2
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| Patched 2, located in 1p32-34, is not mutated in high stage neuroblastoma tumors.
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| Jogi A, Abel F, Sjoberg RM, Toftgard R, Zaphiropoulos PG, Pahlman S, Martinsson T, Axelson H.
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| Int J Oncol 16(5):943-9. 2000
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| 14 | PTCH2
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| Isolation and characterization of human Patched 2 (PTCH2), a putative tumour suppressor gene in basal cell carcinoma and medulloblastoma on chromosome 1p32.
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| Smyth I, et al.
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| Hum Mol Genet 8 : 291-297. 1999
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| 15 | PTCH2
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| PTCH2, a novel human patched gene, undergoing alternative splicing and up-regulated in basal cell carcinomas.
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| Zaphiropoulos PG, et al.
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| Cancer Res 59(4):787-92. 1999
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| 16 | PTCH2, SHH
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| Characterization of two patched receptors for the vertebrate hedgehog protein family.
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| Carpenter D, Stone DM, Brush J, Ryan A, Armanini M, Frantz G, Rosenthal A, de Sauvage FJ.
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| Proc Natl Acad Sci U S A 95 : 13630-13634. 1998
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| 17 | PTCH2
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| Overlapping and non-overlapping Ptch2 expression with Shh during mouse embryogenesis.
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| Motoyama J, et al.
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| Mech Dev 78 : 81-84. 1998
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| 18 | NBCCS2, PTCH2
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| Fan Z, Li J, Du J, Zhang H, Shen Y, Wang CY, Wang S.
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