Citations for
1CCND2, CDC25B, PTBP1, PTBP2, RBL1
Polypyrimidine tract-binding proteins are essential for B cell development.
Monzón-Casanova E, Matheson LS, Tabbada K, Zarnack K, Smith CW, Turner M.
Elife 9. pii: e53557. doi: 10.7554/eLife.53557. 2020
2PTBP2
Axonogenesis Is Coordinated by Neuron-Specific Alternative Splicing Programming and Splicing Regulator PTBP2.
Zhang M, Ergin V, Lin L, Stork C, Chen L, Zheng S.
Neuron 101(4):690-706.e10. doi: 10.1016/j.neuron.2019.01.022. Epub 2019 Feb 4. 2019
3PTBP2
PTBP2 exon 10 inclusion is associated with the progression of CML and it is BCR-ABL1 dependent.
Nandagopalan SR, Agatheeswaran S, Vadlamudi Y, Biswas S, Biswas G, Pattnayak NC, Chakraborty S.
Int J Biochem Cell Biol 109:69-75. doi: 10.1016/j.biocel.2019.01.018. Epub 2019 Feb 3. 2019
4PTBP1, PTBP2, PTBP3
PTB/nPTB: master regulators of neuronal fate in mammals.
Hu J, Qian H, Xue Y, Fu XD.
Biophys Rep 4(4):204-214. doi: 10.1007/s41048-018-0066-y. Epub 2018 Aug 28. 2018
5PTBP2
Association between RNA-binding protein Ptbp2 and germ cell injury in an experimentally-induced unilateral cryptorchidism murine model.
Dou X, Gao J, Gao P, Tang D, Peng D, Mao J, Huang Z, Chen P, Chen H, Ke S, Liang C, Zhang X.
PLoS One 12(10):e0186654. doi: 10.1371/journal.pone.0186654. eCollection 2017. 2017
6PTBP2
Ptbp2 Controls an Alternative Splicing Network Required for Cell Communication during Spermatogenesis.
Hannigan MM, Zagore LL, Licatalosi DD.
Cell Rep 19(12):2598-2612. doi: 10.1016/j.celrep.2017.05.089. 2017
7PTBP1, PTBP2
PTBP1 and PTBP2 Serve Both Specific and Redundant Functions in Neuronal Pre-mRNA Splicing.
Vuong JK, Lin CH, Zhang M, Chen L, Black DL, Zheng S.
Cell Rep 17(10):2766-2775. doi: 10.1016/j.celrep.2016.11.034. 2016
8PTBP1, PTBP2
PTBP1 and PTBP2 Repress Nonconserved Cryptic Exons.
Ling JP, Chhabra R, Merran JD, Schaughency PM, Wheelan SJ, Corden JL, Wong PC.
Cell Rep 17(1):104-113. doi: 10.1016/j.celrep.2016.08.071. 2016
9PTBP1, PTBP2, PTBP3
Human polypyrimidine tract-binding protein interacts with mitochondrial tRNA(Thr) in the cytosol.
Marnef A, Jády BE, Kiss T.
Nucleic Acids Res 44(3):1342-53. doi: 10.1093/nar/gkv1355. Epub 2015 Dec 10. 2016
10PTBP2
RNA Binding Protein Ptbp2 Is Essential for Male Germ Cell Development.
Zagore LL, Grabinski SE, Sweet TJ, Hannigan MM, Sramkoski RM, Li Q, Licatalosi DD.
Mol Cell Biol 35(23):4030-42. doi: 10.1128/MCB.00676-15. Epub 2015 Sep 21. 2015
11PTBP2
The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation.
Li Q, Zheng S, Han A, Lin CH, Stoilov P, Fu XD, Black DL.
Elife 3:e01201. doi: 10.7554/eLife.01201. Epub 2014 Jan 21. Erratum in: Elife. 2017 Oct 09;6:. 2014
12PTBP1, PTBP2
Characterization of a novel posttranslational modification in polypyrimidine tract-binding proteins by SUMO1.
Han W, Wang L, Yin B, Peng X.
BMB Rep 47(4):233-8. 2014
13PTBP1, PTBP2
Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain.
Licatalosi DD, Yano M, Fak JJ, Mele A, Grabinski SE, Zhang C, Darnell RB.
Genes Dev 26(14):1626-42. doi: 10.1101/gad.191338.112. 2012
14DLG4, PTBP1, PTBP2
PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2.
Zheng S, Gray EE, Chawla G, Porse BT, O'Dell TJ, Black DL.
Nat Neurosci 15(3):381-8, S1. doi: 10.1038/nn.3026. 2012
15AICDA, PTBP2
The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNA.
Nowak U, Matthews AJ, Zheng S, Chaudhuri J.
Nat Immunol 12(2):160-6. Epub 2010 Dec 26. 2011
16CELF1, PTBP1, PTBP2, TPM2
CELF and PTB proteins modulate the inclusion of the β-tropomyosin exon 6B during myogenic differentiation.
Sureau A, Saulière J, Expert-Bezançon A, Marie J.
Exp Cell Res 317(1):94-106. Epub 2010 Sep 25. 2011
17PTBP2
Polypyrimidine tract-binding protein 2 binds to selective, intronic messenger RNA and microRNA targets in the mouse testis.
Xu M, Hecht NB.
Biol Reprod 84(3):435-9. Epub 2010 Oct 27. 2011
18HBB, HNRNPH1, PTBP1, PTBP2
A physical and functional link between splicing factors promotes pre-mRNA 3' end processing.
Millevoi S, Decorsière A, Loulergue C, Iacovoni J, Bernat S, Antoniou M, Vagner S.
Nucleic Acids Res 37(14):4672-83. Epub 2009 Jun 8. 2009
19PTBP2, TP53
Polypyrimidine tract binding protein regulates IRES-mediated translation of p53 isoforms.
Grover R, Ray PS, Das S.
Cell Cycle 7(14):2189-98. Epub 2008 May 11. 2008
20PGK2, PTBP2
Polypyrimidine tract binding protein 2 stabilizes phosphoglycerate kinase 2 mRNA in murine male germ cells by binding to its 3'UTR.
Xu M, Hecht NB.
Biol Reprod 76(6):1025-33. Epub 2007 Feb 28. 2007
21PTBP2
Identification and analysis of the human neural polypyrimidine tract binding protein (nPTB) gene promoter region.
Romanelli MG, Lorenzi P, Morandi C.
Gene 15;356:11-8. 2005
22PTBP2
Evolutionary conservation of a 2-kb intronic sequence flanking a tissue-specific alternative exon in the PTBP2 gene.
Rahman L, Bliskovski V, Kaye FJ, Zajac-Kaye M.
Genomics 83(1):76-84. 2004
23PTBP1, PTBP2
Alternative Splicing of Brain-Specific PTB Defines a Tissue-Specific Isoform Pattern That Predicts Distinct Functional Roles.
Rahman L, Bliskovski V, Reinhold W, Zajac-Kaye M.
Genomics 80(3):245. 2002
24PTBP2
Molecular cloning and characterization of human PTB-like protein: a possible retinal autoantigen of cancer-associated retinopathy.
Tateiwa H, Gotoh N, Ichikawa M, Kikuchi T, Yoshimura N.
J Neuroimmunol 120(1-2):161-9. 2001
25PTBP2
Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein.
Markovtsov V, Nikolic JM, Goldman JA, Turck CW, Chou MY, Black DL.
Mol Cell Biol 20(20):7463-79. 2000