1 | NLRC4, PSMC5
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| A Disease-associated Mutant of NLRC4 Shows Enhanced Interaction with SUG1 Leading to Constitutive FADD-dependent Caspase-8 Activation and Cell Death.
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| Raghawan AK, Sripada A, Gopinath G, Pushpanjali P, Kumar Y, Radha V, Swarup G.
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| J Biol Chem 292(4):1218-1230. doi: 10.1074/jbc.M116.763979. Epub 2016 Dec 14.
2017
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2 | NR1I3, PSMC5
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| Proteasomal interaction as a critical activity modulator of the human constitutive androstane receptor.
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| Chen T, Laurenzana EM, Coslo DM, Chen F, Omiecinski CJ.
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| Biochem J 458(1):95-107. doi: 10.1042/BJ20130685.
2014
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3 | PSMC5
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| Role of Sug1, a 19S proteasome ATPase, in the transcription of MHC I and the atypical MHC II molecules, HLA-DM and HLA-DO.
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| Inostroza-Nieves Y, Venkatraman P, Zavala-Ruiz Z.
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| Immunol Lett 147(1-2):67-74. doi: 10.1016/j.imlet.2012.06.005. Epub 2012 Jul 4.
2012
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4 | PLEKHO1, PSMC5, SMURF1
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| CKIP-1 couples Smurf1 ubiquitin ligase with Rpt6 subunit of proteasome to promote substrate degradation.
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| Wang Y, Nie J, Wang Y, Zhang L, Lu K, Xing G, Xie P, He F, Zhang L.
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| EMBO Rep 13(11):1004-11. doi: 10.1038/embor.2012.144. Epub 2012 Oct 2.
2012
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5 | PSMC5, PSMC6
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| C termini of proteasomal ATPases play nonequivalent roles in cellular assembly of mammalian 26 S proteasome.
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| Kim YC, DeMartino GN.
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| J Biol Chem 286(30):26652-66. doi: 10.1074/jbc.M111.246793. Epub 2011 May 31.
2011
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6 | NLRC4, PSMC5
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| Interaction with Sug1 enables Ipaf ubiquitination leading to caspase 8 activation and cell death.
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| Kumar Y, Radha V, Swarup G.
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| Biochem J 427(1):91-104. doi: 10.1042/BJ20091349.
2010
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7 | PSMC5
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| The 19S proteasome positively regulates histone methylation at cytokine inducible genes.
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| Koues OI, Dudley RK, Mehta NT, Greer SF.
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| Biochim Biophys Acta 1789(11-12):691-701. doi: 10.1016/j.bbagrm.2009.07.006. Epub 2009 Aug 3.
2009
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8 | NCOA3, PSMC5
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| SUG-1 plays proteolytic and non-proteolytic roles in the control of retinoic acid target genes via its interaction with SRC-3.
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| Ferry C, Gianni M, Lalevée S, Bruck N, Plassat JL, Raska I Jr, Garattini E, Rochette-Egly C.
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| J Biol Chem 284(12):8127-35. doi: 10.1074/jbc.M808815200. Epub 2009 Jan 13.
2009
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9 | PSMC5
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| The 19S proteasome ATPase Sug1 plays a critical role in regulating MHC class II transcription.
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| Bhat KP, Turner JD, Myers SE, Cape AD, Ting JP, Greer SF.
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| Mol Immunol 45(8):2214-24. doi: 10.1016/j.molimm.2007.12.001. Epub 2008 Jan 22.
2008
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10 | PSMC5
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| Mouse homologue of yeast Prp19 interacts with mouse SUG1, the regulatory subunit of 26S proteasome.
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| Sihn CR, Cho SY, Lee JH, Lee TR, Kim SH.
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| Biochem Biophys Res Commun 356(1):175-80. Epub 2007 Mar 2.
2007
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11 | ATXN3, PSMC5
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| p45, an ATPase subunit of the 19S proteasome, targets the polyglutamine disease protein ataxin-3 to the proteasome.
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| Wang H, Jia N, Fei E, Wang Z, Liu C, Zhang T, Fan J, Wu M, Chen L, Nukina N, Zhou J, Wang G.
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| J Neurochem 101(6):1651-61. Epub 2007 Feb 14.
2007
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12 | MYO18B, PSMC5
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| MYO18B interacts with the proteasomal subunit Sug1 and is degraded by the ubiquitin-proteasome pathway.
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| Inoue T, Kon T, Ajima R, Ohkura R, Tani M, Yokota J, Sutoh K.
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| Biochem Biophys Res Commun 342(3):829-34. Epub 2006 Feb 17.
2006
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13 | PSMC5
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| Involvement of suppressor for Gal 1 in the ubiquitin/proteasome-mediated degradation of estrogen receptors.
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| Masuyama H, Hiramatsu Y.
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| J Biol Chem 279(13):12020-6. Epub 2003 Dec 30.
2004
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14 | PSMC5, SP1
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| Human Sug1/p45 is involved in the proteasome-dependent degradation of Sp1.
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| Su K, Yang X, Roos MD, Paterson AJ, Kudlow JE.
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| Biochem J 348 Pt 2:281-9. 2000
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15 | SMARCD2, PSMC5
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| Evidence for evolutionary conservation of a physical linkage between the human BAF60b, a subunit of SWI/SNF complex, and thyroid hormone receptor interacting protein-1 genes on chromosome 17.
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| Surabhi RM, et al.
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| Genome 42(3):545-9. 1999
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16 | AFG3L1, AFG3L2, NSF, NVL, PBD2, PEX1, PEX6, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMC6, VPS4B, SPAST, VCP
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| AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes.
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| Neuwald AF, Aravind L, Spouge JL, Koonin EV.
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| Genome Res 9(1):27-43 1999
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17 | PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMC6
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| Chromosomal localization and immunological analysis of a family of human 26S proteasomal ATPases.
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| Tanahashi N, Suzuki M, Fujiwara T, Takahashi E, Shimbara N, Chung CH, Tanaka K.
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| Biochem Biophys Res Commun 243(1):229-32. 1998
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18 | PSMC5, TRIP1P
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| Genomic structure and chromosomal location of the human TGFbeta-receptor interacting protein-1 (TRIP-1) gene to 1p34.1.
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| Galli-Stauber C, et al.
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| FEBS Lett 426 : 279-282. 1998
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19 | PSMC3, PSMC3P, PSMC5
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| Localization of genes encoding two human one-domain members of the AAA family : PSMC5 (the thyroid hormone receptor-interacting protein, TRIP1) and PSMC3 (the TAT-binding protein, TBP1).
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| Hoyle J, et al.
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| Hum Genet 99 : 285-288. 1997
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