Citations for
1CTCFL, PRSS50
Transcription factor BORIS (Brother of the Regulator of Imprinted Sites) directly induces expression of a cancer-testis antigen, TSP50, through regulated binding of BORIS to the promoter.
Kosaka-Suzuki N, Suzuki T, Pugacheva EM, Vostrov AA, Morse HC 3rd, Loukinov D, Lobanenkov V.
J Biol Chem 286(31):27378-88. Epub 2011 Jun 9. 2011
2PRSS50
Testes-specific protease 50 (TSP50) promotes cell proliferation through the activation of the nuclear factor κB (NF-κB) signalling pathway.
Song ZB, Bao YL, Zhang Y, Mi XG, Wu P, Wu Y, Yu CL, Sun Y, Zheng LH, Huang YX, Liu B, Li YX.
Biochem J 436(2):457-67. 2011
3PRSS50
Knockdown of TSP50 inhibits cell proliferation and induces apoptosis in P19 cells.
Zhou L, Bao YL, Zhang Y, Wu Y, Yu CL, Huang YX, Sun Y, Zheng LH, Li YX.
IUBMB Life 62(11):825-32.PMID: 21086474 2010
4FGF2, PRSS50
Basic FGF downregulates TSP50 expression via the ERK/Sp1 pathway.
Wang M, Bao YL, Wu Y, Yu CL, Meng XY, Huang YX, Sun Y, Zheng LH, Li YX.
J Cell Biochem 111(1):75-81.PMID: 20506264 2010
5PRSS50
Differential methylation of TSP50 and mTSP50 genes in different types of human tissues and mouse spermatic cells.
Huang Y, Wang Y, Wang M, Sun B, Li Y, Bao Y, Tian K, Xu H.
Biochem Biophys Res Commun 374(4):658-61. Epub 2008 Jul 26.PMID: 18662669 2008
6PRSS50
Identification and characterization of the human testes-specific protease 50 gene promoter.
Wang M, Bao YL, Wu Y, Yu CL, Meng X, Xu HP, Li YX.
DNA Cell Biol 27(6):307-14.PMID: 18462069 2008
7PRSS50
TSP50 encodes a testis-specific protease and is negatively regulated by p53.
Xu H, Shan J, Jurukovski V, Yuan L, Li J, Tian K.
Cancer Res 67(3):1239-45.PMID: 17283160 2007
8PRSS50
Localization and expression of TSP50 protein in human and rodent testes.
Xu HP, Yuan L, Shan J, Feng H.
Urology 64(4):826-32.PMID: 15491742 2004
9PRSS50
TSP50, a possible protease in human testes, is activated in breast cancer epithelial cells.
Shan J, Yuan L, Xiao Q, Chiorazzi N, Budman D, Teichberg S, Xu HP.
Cancer Res 62(1):290-4. 2002
10PRSS50
Isolation of a novel gene, TSP50, by a hypomethylated DNA fragment in human breast cancer.
Yuan L, Shan J, De Risi D, Broome J, Lovecchio J, Gal D, Vinciguerra V,Xu HP.
Cancer Res 59(13):3215-21. 1999