1 | CTCFL, PRSS50
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| Transcription factor BORIS (Brother of the Regulator of Imprinted Sites) directly induces expression of a cancer-testis antigen, TSP50, through regulated binding of BORIS to the promoter.
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| Kosaka-Suzuki N, Suzuki T, Pugacheva EM, Vostrov AA, Morse HC 3rd, Loukinov D, Lobanenkov V.
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| J Biol Chem 286(31):27378-88. Epub 2011 Jun 9. 2011
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2 | PRSS50
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| Testes-specific protease 50 (TSP50) promotes cell proliferation through the activation of the nuclear factor κB (NF-κB) signalling pathway.
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| Song ZB, Bao YL, Zhang Y, Mi XG, Wu P, Wu Y, Yu CL, Sun Y, Zheng LH, Huang YX, Liu B, Li YX.
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| Biochem J 436(2):457-67.
2011
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3 | PRSS50
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| Knockdown of TSP50 inhibits cell proliferation and induces apoptosis in P19 cells.
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| Zhou L, Bao YL, Zhang Y, Wu Y, Yu CL, Huang YX, Sun Y, Zheng LH, Li YX.
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| IUBMB Life 62(11):825-32.PMID: 21086474 2010
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4 | FGF2, PRSS50
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| Basic FGF downregulates TSP50 expression via the ERK/Sp1 pathway.
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| Wang M, Bao YL, Wu Y, Yu CL, Meng XY, Huang YX, Sun Y, Zheng LH, Li YX.
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| J Cell Biochem 111(1):75-81.PMID: 20506264 2010
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5 | PRSS50
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| Differential methylation of TSP50 and mTSP50 genes in different types of human tissues and mouse spermatic cells.
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| Huang Y, Wang Y, Wang M, Sun B, Li Y, Bao Y, Tian K, Xu H.
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| Biochem Biophys Res Commun 374(4):658-61. Epub 2008 Jul 26.PMID: 18662669 2008
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6 | PRSS50
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| Identification and characterization of the human testes-specific protease 50 gene promoter.
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| Wang M, Bao YL, Wu Y, Yu CL, Meng X, Xu HP, Li YX.
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| DNA Cell Biol 27(6):307-14.PMID: 18462069 2008
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7 | PRSS50
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| TSP50 encodes a testis-specific protease and is negatively regulated by p53.
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| Xu H, Shan J, Jurukovski V, Yuan L, Li J, Tian K.
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| Cancer Res 67(3):1239-45.PMID: 17283160 2007
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8 | PRSS50
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| Localization and expression of TSP50 protein in human and rodent testes.
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| Xu HP, Yuan L, Shan J, Feng H.
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| Urology 64(4):826-32.PMID: 15491742 2004
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9 | PRSS50
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| TSP50, a possible protease in human testes, is activated in breast cancer epithelial cells.
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| Shan J, Yuan L, Xiao Q, Chiorazzi N, Budman D, Teichberg S, Xu HP.
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| Cancer Res 62(1):290-4. 2002
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10 | PRSS50
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| Isolation of a novel gene, TSP50, by a hypomethylated DNA fragment in human breast cancer.
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| Yuan L, Shan J, De Risi D, Broome J, Lovecchio J, Gal D, Vinciguerra V,Xu HP.
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| Cancer Res 59(13):3215-21. 1999
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