| 1 | PRSS3
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| Small molecule inhibitors of mesotrypsin from a structure-based docking screen.
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| Kayode O, Huang Z, Soares AS, Caulfield TR, Dong Z, Bode AM, Radisky ES.
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| PLoS One 12(5):e0176694. doi: 10.1371/journal.pone.0176694. eCollection 2017.
2017
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| 2 | PRSS3, TFPI2
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| PO-44 - Tissue factor pathway inhibitor-2 (TFPI-2) is cleaved by PRSS3: implication for tumor endothelial cells migration.
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| Ghilardi C, Anastasia A, Avigni R, Lupi M, Giavazzi R, Bani MR.
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| Thromb Res 140 Suppl 1:S192-3. doi: 10.1016/S0049-3848(16)30177-3. Epub 2016 Apr 8.
2016
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| 3 | PRSS3
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| Trypsinogen 4 boosts tumor endothelial cells migration through proteolysis of tissue factor pathway inhibitor-2.
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| Ghilardi C, Silini A, Figini S, Anastasia A, Lupi M, Fruscio R, Giavazzi R, Bani MR.
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| Oncotarget 6(29):28389-400. doi: 10.18632/oncotarget.4949.
2015
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| 4 | PRSS3, TFPI2
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| Trypsinogen 4 boosts tumor endothelial cells migration through proteolysis of tissue factor pathway inhibitor-2.
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| Ghilardi C, Silini A, Figini S, Anastasia A, Lupi M, Fruscio R, Giavazzi R, Bani MR.
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| Oncotarget 6(29):28389-400. doi: 10.18632/oncotarget.4949.
2015
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| 5 | PRSS3
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| PRSS3 expression is associated with tumor progression and poor prognosis in epithelial ovarian cancer.
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| Ma R, Ye X, Cheng H, Ma Y, Cui H, Chang X.
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| Gynecol Oncol 137(3):546-52. doi: 10.1016/j.ygyno.2015.02.022. Epub 2015 Feb 28.
2015
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| 6 | CASP14, PRSS3, PSAP
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| Mesotrypsin and caspase-14 participate in prosaposin processing: potential relevance to epidermal permeability barrier formation.
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| Yamamoto-Tanaka M, Motoyama A, Miyai M, Matsunaga Y, Matsuda J, Tsuboi R, Hibino T.
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| J Biol Chem 289(29):20026-38. doi: 10.1074/jbc.M113.543421. Epub 2014 May 28.
2014
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| 7 | PRSS3, TFPI2
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| Mesotrypsin and caspase-14 participate in prosaposin processing: potential relevance to epidermal permeability barrier formation.
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| Yamamoto-Tanaka M, Motoyama A, Miyai M, Matsunaga Y, Matsuda J, Tsuboi R, Hibino T.
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| J Biol Chem 289(29):20026-38. doi: 10.1074/jbc.M113.543421. Epub 2014 May 28.
2014
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| 8 | PRSS3, SPINK5
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| Keratinocyte-specific mesotrypsin contributes to the desquamation process via kallikrein activation and LEKTI degradation.
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| Miyai M, Matsumoto Y, Yamanishi H, Yamamoto-Tanaka M, Tsuboi R, Hibino T.
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| J Invest Dermatol 134(6):1665-1674. doi: 10.1038/jid.2014.3. Epub 2014 Jan 3.
2014
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| 9 | F2RL1, PRSS3
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| Autocrine extra-pancreatic trypsin 3 secretion promotes cell proliferation and survival in esophageal adenocarcinoma.
|
| Han S, Lee CW, Trevino JG, Hughes SJ, Sarosi GA Jr.
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| PLoS One 8(10):e76667. doi: 10.1371/journal.pone.0076667. eCollection 2013.
2013
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| 10 | PRSS3
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| PRSS3/mesotrypsin is a therapeutic target for metastatic prostate cancer.
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| Hockla A, Miller E, Salameh MA, Copland JA, Radisky DC, Radisky ES.
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| Mol Cancer Res 10(12):1555-66. doi: 10.1158/1541-7786.MCR-12-0314.
2012
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| 11 | PRSS3
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| PRSS3 promotes tumour growth and metastasis of human pancreatic cancer.
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| Jiang G, Cao F, Ren G, Gao D, Bhakta V, Zhang Y, Cao H, Dong Z, Zang W, Zhang S, Wong HH, Hiley C, Crnogorac-Jurcevic T, Lemoine NR, Wang Y.
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| Gut 59(11):1535-44. doi: 10.1136/gut.2009.200105.
2010
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| 12 | PRSS3
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| Keratinocytes synthesize enteropeptidase and multiple forms of trypsinogen during terminal differentiation.
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| Nakanishi J, Yamamoto M, Koyama J, Sato J, Hibino T.
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| J Invest Dermatol 130(4):944-52. doi: 10.1038/jid.2009.364. Epub 2009 Nov 19.
2010
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| 13 | PRSS3
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| The amyloid precursor protein/protease nexin 2 Kunitz inhibitor domain is a highly specific substrate of mesotrypsin.
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| Salameh MA, Robinson JL, Navaneetham D, Sinha D, Madden BJ, Walsh PN, Radisky ES.
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| J Biol Chem 285(3):1939-49. doi: 10.1074/jbc.M109.057216. Epub 2009 Nov 17.
2010
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| 14 | PRSS3
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| Trypsinogen IV, serotonin transporter transcript levels and serotonin content are increased in small intestine of irritable bowel syndrome patients.
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| Kerckhoffs AP, Ter Linde JJ, Akkermans LM, Samsom M.
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| Neurogastroenterol Motil 20(8):900-7. doi: 10.1111/j.1365-2982.2008.01100.x. Epub 2008 Mar 7.
2008
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| 15 | PRSS3
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| Regional distribution of human trypsinogen 4 in human brain at mRNA and protein level.
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| Tóth J, Siklódi E, Medveczky P, Gallatz K, Németh P, Szilágyi L, Gráf L, Palkovits M.
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| Neurochem Res 32(9):1423-33. Epub 2007 Apr 4.
2007
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| 16 | PRSS3
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| Human mesotrypsin exhibits restricted S1' subsite specificity with a strong preference for small polar side chains.
|
| Szepessy E, Sahin-Tóth M.
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| FEBS J 273(13):2942-54. Epub 2006 Jun 5.
2006
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| 17 | PRSS3
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| Epigenetic silencing of the PRSS3 putative tumor suppressor gene in non-small cell lung cancer.
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| Marsit CJ, Okpukpara C, Danaee H, Kelsey KT.
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| Mol Carcinog 44(2):146-50.
2005
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| 18 | PRSS3
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| Human mesotrypsin is a unique digestive protease specialized for the degradation of trypsin inhibitors.
|
| Szmola R, Kukor Z, Sahin-Tóth M.
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| J Biol Chem 278(49):48580-9. Epub 2003 Sep 24.
2003
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| 19 | PRSS1, PRSS2, PRSS3, PRSS3P2, TRB@, TRBC2, TRBD1, TRBD2, TRBJ1-1, TRBJ1-2, TRBJ1-3, TRBJ1-4, TRBJ1-5, TRBJ1-6, TRBJ2-1, TRBJ2-2, TRBJ2-2P, TRBJ2-3, TRBJ2-4, TRBJ2-5, TRBJ2-6, TRBJ2-7, TRBJ@, TRBV1, TRBV10-1, TRBV10-2, TRBV10-3, TRBV11-1, TRBV11-2, TRBV11-3, TRBV12-1, TRBV12-2, TRBV12-3, TRBV12-4, TRBV12-5, TRBV13, TRBV14, TRBV15, TRBV16, TRBV17, TRBV18, TRBV19, TRBV2, TRBV20-1, TRBV21-1, TRBV22, TRBV22, TRBV23-1, TRBV24-1, TRBV25-1, TRBV26, TRBV27, TRBV28, TRBV29-1, TRBV3-1, TRBV3-2, TRBV30, TRBV4-1, TRBV4-2, TRBV4-3, TRBV5-1, TRBV5-2, TRBV5-3, TRBV5-4, TRBV5-5, TRBV5-6, TRBV5-7, TRBV5-8, TRBV6-1, TRBV6-2, TRBV6-3, TRBV6-4, TRBV6-5, TRBV6-6, TRBV6-7, TRBV6-8, TRBV6-9, TRBV7-1, TRBV7-2, TRBV7-4, TRBV7-5, TRBV7-6, TRBV7-7, TRBV7-8, TRBV7-9, TRBV8-1, TRBV8-2, TRBV9, TRBV@, TRBVA, TRBVB, TRY7
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| The complete 685-kilobase DNA sequence of the human beta T cell receptor locus.
|
| Rowen L, Koop BF, Hood L.
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| Science 272(5269):1755-62. 1996
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| 20 | PRSS3
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| Cloning of the cDNA encoding human brain trypsinogen and characterization of its product.
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| Wiegand U, Corbach S, Minn A, Kang J, Muller-Hill B.
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| Gene 136 : 167-175. 1993
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| 21 | PRSS3
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| Nucleotide sequence of the human pancreatic trypsinogen III cDNA.
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| Tani T, Kawashima I, Mita K, Takiguchi Y.
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| Nucleic Acids Res 18(6):1631. 1990
|