| 1 | AGRN, PRSS12
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| Genes encoding agrin (AGRN) and neurotrypsin (PRSS12) are associated with muscle mass, strength and plasma C-terminal agrin fragment concentration.
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| Pratt J, Whitton L, Ryan A, Juliusdottir T, Dolan J, Conroy J, Narici M, De Vito G, Boreham C.
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| Geroscience Jan 7. doi: 10.1007/s11357-022-00721-1. Epub ahead of print. 2023
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| 2 | ITM2A, PRSS12
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| Mental retardation-related protease, motopsin (prss12), binds to the BRICHOS domain of the integral membrane protein 2a
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| Mitsui S, Osako Y, Yuri K.
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| Cell Biol Int. Jan;38(1):117-23. doi: 10.1002/cbin.10164. Epub 2013 Sep 24 2014
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| 3 | PRSS12, SEZ6
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| A mental retardation gene, motopsin/prss12, modulates cell morphology by interaction with seizure-related gene 6.
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| Mitsui S, Hidaka C, Furihata M, Osako Y, Yuri K.
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| Biochem Biophys Res Commun 436(4):638-44. doi: 10.1016/j.bbrc.2013.04.112. Epub 2013 Jun 11.
2013
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| 4 | PRSS12
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| Presenilins regulate neurotrypsin gene expression and neurotrypsin-dependent agrin cleavage via cyclic AMP response element-binding protein (CREB) modulation.
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| Almenar-Queralt A, Kim SN, Benner C, Herrera CM, Kang DE, Garcia-Bassets I, Goldstein LS.
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| J Biol Chem. Dec 6;288(49):35222-36. doi: 10.1074/jbc.M113.513705. Epub 2013 Oct 21. 2013
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| 5 | PRSS12
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| A mental retardation gene, motopsin/neurotrypsin/prss12, modulates hippocampal function and social interaction.
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| Mitsui S, Osako Y, Yokoi F, Dang MT, Yuri K, Li Y, Yamaguchi N.
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| Eur J Neurosci 30(12):2368-78. doi: 10.1111/j.1460-9568.2009.07029.x. Epub 2009 Dec 10.
2009
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| 6 | PRSS12, TMPRSS5
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| Mosaic serine proteases in the mammalian central nervous system.
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| Mitsui S, Watanabe Y, Yamaguchi T, Yamaguchi N.
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| Front Biosci 13:1991-2000. Review.
2008
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| 7 | PRSS12
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| NMR solution structure of the neurotrypsin Kringle domain.
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| Ozhogina OA, Grishaev A, Bominaar EL, Patthy L, Trexler M, Llinás M.
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| Biochemistry 47(47):12290-8. doi: 10.1021/bi800555z.
2008
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| 8 | PRSS12
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| Neurotrypsin cleaves agrin locally at the synapse.
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| Stephan A, Mateos JM, Kozlov SV, Cinelli P, Kistler AD, Hettwer S, Rülicke T, Streit P, Kunz B, Sonderegger P.
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| FASEB J 22(6):1861-73. doi: 10.1096/fj.07-100008. Epub 2008 Jan 29.
2008
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| 9 | MRAR2, PRSS12
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| Enzymatic properties and localization of motopsin (PRSS12), a protease whose absence causes mental retardation.
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| Mitsui S, Yamaguchi N, Osako Y, Yuri K.
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| Brain Res 1136(1):1-12. Epub 2007 Jan 16.
2007
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| 10 | PRSS12
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| The expression of a motoneuron-specific serine protease, motopsin (PRSS12), after facial nerve axotomy in mice.
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| Numajiri T, Mitsui S, Hisa Y, Ishida T, Nishino K, Yamaguchi N.
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| J Plast Reconstr Aesthet Surg 59(4):393-7.
2006
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| 11 | FENIB, MRAR2, PRSS12, SERPINI1
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| Extracellular proteases and their inhibitors ingenetic diseases of the central nervous system.
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| Molinari F, Meskanaite V, Munnich A, Sonderegger P, Colleaux L.
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| Hum Mol Genet 12 Suppl 2:R195-200. Epub 2003 Aug 12. 2003
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| 12 | MRAR2, PRSS12
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| Truncating neurotrypsin mutation in autosomal recessive nonsyndromic mental retardation.
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| Molinari F, Rio M, Meskenaite V, Encha-Razavi F, Augé J, Bacq D, Briault S, Vekemans M, Munnich A, Attié-Bitach T, Sonderegger P, Colleaux L.
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| Science 298(5599):1779-81.
2002
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| 13 | PRSS12
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| Assignment1 of the gene encoding the neuronal multidomain serine protease neurotrypsin (PRSS12) to human chromosome band 4q25-->q26 by in situ hybridization.
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| Kozlov SV, et al.
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| Cytogenet Cell Genet 84(1-2):107-8. No abstract available 1999
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| 14 | PRSS12
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| Cloning and sequencing of the cDNA encoding human neurotrypsin.
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| Proba K, et al.
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| Biochim Biophys Acta 1396(2):143-7. 1998
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| 15 | PRSS12
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| Neurotrypsin, a novel multidomain serine protease expressed in the nervous system.
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| Gschwend TP, et al.
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| Mol Cell Neurosci 9(3):207-19. 1997
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