Citations for
1PRPF8, SLU7
Dynamic protein-RNA interactions in mediating splicing catalysis.
Chung CS, Tseng CK, Lai YH, Wang HF, Newman AJ, Cheng SC.
Nucleic Acids Res 47(2):899-910. doi: 10.1093/nar/gky1089. 2019
2PRPF8, SNRNP200
Variability in clinical phenotypes of PRPF8-linked autosomal dominant retinitis pigmentosa correlates with differential PRPF8/SNRNP200 interactions.
Escher P, Passarin O, Munier FL, Tran VH, Vaclavik V.
Ophthalmic Genet 39(1):80-86. doi: 10.1080/13816810.2017.1393825. Epub 2017 Oct 31. 2018
3EFTUD2, PRPF8, SNRNP200
Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.
Malinová A, Cvačková Z, Matějů D, Hořejší Z, Abéza C, Vandermoere F, Bertrand E, Staněk D, Verheggen C.
J Cell Biol 216(6):1579-1596. doi: 10.1083/jcb.201701165. Epub 2017 May 17. 2017
4PRPF18, PRPF8, SLU7
Structure of a spliceosome remodelled for exon ligation.
Fica SM, Oubridge C, Galej WP, Wilkinson ME, Bai XC, Newman AJ, Nagai K.
Nature 542(7641):377-380. doi: 10.1038/nature21078. Epub 2017 Jan 11. 2017
5CWC22, PRPF8, RBM22, SLU7
An Atomic Structure of the Human Spliceosome.
Zhang X, Yan C, Hang J, Finci LI, Lei J, Shi Y.
Cell 169(5):918-929.e14. doi: 10.1016/j.cell.2017.04.033. Epub 2017 May 11. 2017
6PRPF3, PRPF31, PRPF8, RP11, RP13, RP18
Mutations in pre-mRNA processing factors 3, 8, and 31 cause dysfunction of the retinal pigment epithelium.
Farkas MH, Lew DS, Sousa ME, Bujakowska K, Chatagnon J, Bhattacharya SS, Pierce EA, Nandrot EF.
Am J Pathol 184(10):2641-52. doi: 10.1016/j.ajpath.2014.06.026. 2014
7PRPF8, SNRNP200
Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8.
Mozaffari-Jovin S, Wandersleben T, Santos KF, Will CL, Lührmann R, Wahl MC.
Science 341(6141):80-4. doi: 10.1126/science.1237515. Epub 2013 May 23. 2013
8DHX16, DHX38, GPKOW, PRPF8, PRPF8, SLU7
Dynamic protein-protein interaction wiring of the human spliceosome.
Hegele A, Kamburov A, Grossmann A, Sourlis C, Wowro S, Weimann M, Will CL, Pena V, Lührmann R, Stelzl U.
Mol Cell 45(4):567-80. doi: 10.1016/j.molcel.2011.12.034. 2012
9PRPF3, PRPF31, PRPF8, RP11, RP13, RP18
PRPF mutations are associated with generalized defects in spliceosome formation and pre-mRNA splicing in patients with retinitis pigmentosa.
Tanackovic G, Ransijn A, Thibault P, Abou Elela S, Klinck R, Berson EL, Chabot B, Rivolta C.
Hum Mol Genet 20(11):2116-30. Epub 2011 Mar 5. 2011
10PRPF3, PRPF31, PRPF8
Temporal and tissue specific regulation of RP-associated splicing factor genes PRPF3, PRPF31 and PRPC8--implications in the pathogenesis of RP.
Cao H, Wu J, Lam S, Duan R, Newnham C, Molday RS, Graziotto JJ, Pierce EA, Hu J.
PLoS One 6(1):e15860. 2011
11PRPF8, RP13
Prognosis for splicing factor PRPF8 retinitis pigmentosa, novel mutations and correlation between human and yeast phenotypes.
Towns KV, Kipioti A, Long V, McKibbin M, Maubaret C, Vaclavik V, Ehsani P, Springell K, Kamal M, Ramesar RS, Mackey DA, Moore AT, Mukhopadhyay R, Webster AR, Black GC, O'Sullivan J, Bhattacharya SS, Pierce EA, Beggs JD, Inglehearn CF.
Hum Mutat 31(5):E1361-76. 2010
12RP9, RP11, RP13, RP18, PRPF3, PRPF8, PRPF31
Transcriptional expression of cis-acting and trans-acting splicing mutations cause autosomal dominant retinitis pigmentosa.
Gamundi MJ, Hernan I, Muntanyola M, Maseras M, L—pez-Romero P, Alvarez R, Dopazo A, Borrego S, Carballo M.
Hum Mutat 29(6):869-78. 2008
13PRPF8
Structural elucidation of a PRP8 core domain from the heart of the spliceosome.
Ritchie DB, Schellenberg MJ, Gesner EM, Raithatha SA, Stuart DT, Macmillan AM.
Nat Struct Mol Biol 15(11):1199-205. Epub 2008 Oct 2. 2008
14PRPF8
Structure and function of an RNase H domain at the heart of the spliceosome.
Pena V, Rozov A, Fabrizio P, Lührmann R, Wahl MC.
EMBO J 27(21):2929-40. Epub 2008 Oct 9. 2008
15PRPF8
Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa.
Pena V, Liu S, Bujnicki JM, Luhrmann R, Wahl MC.
Mol Cell 25(4):615-24. 2007
16PRPF8, RP13
prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeast.
Boon KL, Grainger RJ, Ehsani P, Barrass JD, Auchynnikava T, Inglehearn CF, Beggs JD.
Nat Struct Mol Biol 14(11):1077-1083. Epub 2007 Oct 14. 2007
17PRPF8
Clinical phenotype of an Italian family with a new mutation in the PRPF8 gene.
Testa F, Ziviello C, Rinaldi M, Rossi S, Di Iorio V, Interlandi E, Ciccodicola A, Banfi S, Simonelli F.
Eur J Ophthalmol 16(5):779-81. 2006
18PRPF8
ARP2 a novel protein involved in apoptosis of LNCaP cells shares a high degree homology with splicing factor Prp8.
Tapia-Vieyra JV, Arellano RO, Mas-Oliva J.
Mol Cell Biochem 269(1-2):189-201. 2005
19PRPF3,PRPF31,PRPF8
Mutations in the pre-mRNA splicing-factor genes PRPF3, PRPF8, and PRPF31 in Spanish families with autosomal dominant retinitis pigmentosa.
Martinez-Gimeno M, Gamundi MJ, Hernan I, Maseras M, Milla E, Ayuso C, Garcia-Sandoval B, Beneyto M, Vilela C, Baiget M, Antinolo G, Carballo M.
Invest Ophthalmol Vis Sci 44(5):2171-7. 2003
20PRPF8, RP13
Clinical characterization, linkage analysis, and PRPC8 mutation analysis of a family with autosomal dominant retinitis pigmentosa type 13 (RP13).
van Lith-Verhoeven JJ, van der Velde-Visser SD, Sohocki MM, Deutman AF, Brink HM, Cremers FP, Hoyng CB.
Ophthalmic Genet 23(1):1-12. 2002
21PRPF8
Mutations in the pre-mRNA splicing factor gene PRPC8 in autosomal dominant retinitis pigmentosa (RP13).
McKie AB, McHale JC, Keen TJ, Tarttelin EE, Goliath R, van Lith-Verhoeven JJ, Greenberg J, Ramesar RS, Hoyng CB, Cremers FP, Mackey DA, Bhattacharya SS, Bird AC, Markham AF, Inglehearn CF.
Hum Mol Genet 10(15):1555-62. 2001
22PRPF3,PRPF8,PRPF31
Mapping of the human HPRP3 and HPRP4 genes encoding U4/U6-associated splicing factors to chromosomes 1q21.1 and 9q31-q33.
Heng HH, Wang A, Hu J.
Genomics 48(2):273-5. No abstract available. 1998
23PRPF8, SNRNP40
The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein.
Achsel T, Ahrens K, Brahms H, Teigelkamp S, Luhrmann R.
Mol Cell Biol 18(11):6756-66. 1998
24PRPF3,PRPF8,PRPF31
Identification and characterization of human genes encoding Hprp3p and Hprp4p, interacting components of the spliceosome.
Wang A, Forman-Kay J, Luo Y, Luo M, Chow YH, Plumb J, Friesen JD, Tsui LC, Heng HH, Woolford JL Jr, Hu J.
Hum Mol Genet 6(12):2117-26. 1997